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Research Output 1978 2019

2000
69 Citations (Scopus)

Lipoproteins and their subfractions in psoriatic arthritis: identification of an atherogenic profile with active joint disease

Jones, S. M., Harris, C. P., Lloyd, J., Stirling, C. A., Reckless, J. P. & McHugh, N. J., Nov 2000, In : Annals of the Rheumatic Diseases. 59, 11, p. 904-909 6 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Joint Diseases
HDL Cholesterol
Lipoproteins
Lipids
14 Citations (Scopus)

MHC class II associations with autoantibody and T cell immune responses to the scleroderma autoantigen topoisomerase I

Rands, A. L., Whyte, J., Cox, B., Hall, N. D. & McHugh, N. J., Dec 2000, In : Journal of Autoimmunity. 15, 4, p. 451-458 8 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Systemic Scleroderma
Autoantibodies
T-Lymphocytes
Alleles
1999
65 Citations (Scopus)

Clinical and serological associations with anti-RNA polymerase antibodies in systemic sclerosis

Harvey, G. R., Butts, S., Rands, A. L., Patel, Y. & McHugh, N. J., Aug 1999, In : Clinical And Experimental Immunology. 117, 2, p. 395-402 8 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Type I DNA Topoisomerase
DNA-Directed RNA Polymerases
Antibodies
Skin
5 Citations (Scopus)

Minocycline-induced lupus and autoimmune phenomena

McHugh, N. J., 1 Aug 1999, In : Lupus. 8, 417, p. 417-418 2 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Serologic abnormalities in systemic sclerosis

Harvey, G. R. & McHugh, N. J., Nov 1999, In : Current Opinion in Rheumatology. 11, 6, p. 495-502 8 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Autoantibodies
Lymphocytes
Antigens
RNA Polymerase III
1997
7 Citations (Scopus)

Bilateral hip replacements in a man with cystic fibrosis and episodic arthritis

Jones, S. M., McKay, K. M. & McHugh, N. J., 1997, In : British Journal of Rheumatology. 36, 2, p. 298-299 2 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Characterization of antinucleolar antibody reactivity in patients with systemic sclerosis and their relatives

Harvey, G., Black, C., Maddison, P. & McHugh, N., Mar 1997, In : Journal of Rheumatology. 24, 3, p. 477-484 8 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Antibody Specificity
Antibodies
Spouses
Cross-Sectional Studies
31 Citations (Scopus)

Expression of the cutaneous lymphocyte antigen and its counter-receptor E-selectin in the skin and joints of patients with psoriatic arthritis

Jones, S. M., Dixey, J., Hall, N. D. & McHugh, N. J., 7 Jul 1997, In : British Journal of Rheumatology. 36, 7, p. 748-757 10 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
E-Selectin
Joints
Lymphocytes
Antigens
1996
20 Citations (Scopus)
Type I DNA Topoisomerase
RNA Polymerase II
Systemic Scleroderma
DNA-Directed RNA Polymerases
Antibodies
131 Citations (Scopus)

Quantitative nailfold capillaroscopy findings in a population with connective tissue disease and in normal healthy controls

Kabasakal, Y., Elvins, D. M., Ring, E. F. & McHugh, N. J., Sep 1996, In : Annals of the Rheumatic Diseases. 55, 8, p. 507-512 6 p.

Research output: Contribution to journalArticle

Microscopic Angioscopy
Connective Tissue Diseases
Tissue
Systemic Scleroderma
Population
30 Citations (Scopus)

VCAM-1 expression on endothelium in lesions from cutaneous lupus erythematosus is increased compared with systemic and localized scleroderma

Jones, S. M., Mathew, C. M., Dixey, J., Lovell, C. R. & McHugh, N. J., Nov 1996, In : British Journal of Dermatology. 135, 5, p. 678-686 9 p.

Research output: Contribution to journalArticle

Cutaneous Lupus Erythematosus
Localized Scleroderma
Vascular Cell Adhesion Molecule-1
Systemic Scleroderma
Endothelium
1995

Atypical antineutrophil cytoplasmic antibodies in patients with ankylosing spondylitis

Koh, W. H., Dunphy, J., Dixey, J., Calin, A., McHugh, N. J. & Maddison, P. J., 7 Jul 1995, In : British Journal of Rheumatology. 34, 7, p. 695-696 2 p.

Research output: Contribution to journalArticle

Characterisation of anticytoplasmic antibodies and their clinical associations

Koh, W. H., Dunphy, J., Whyte, J., Dixey, J. & McHugh, N. J., 1995, In : Annals of the Rheumatic Diseases. 54, 4, p. 269-273 5 p.

Research output: Contribution to journalArticle

Antibodies
Speckle
Staining and Labeling
Immunoblotting
Fluorescent Antibody Technique

Detection of anti-topoisomerase I antibodies using a full length human topoisomerase I recombinant protein purified from a baculovirus expression system

Whyte, J., Earnshaw, W. C., Champoux, J. J., Parker, L. H., Stewart, L., Hall, N. D. & McHugh, N. J., May 1995, In : Clinical And Experimental Immunology. 100, 2, p. 214-218 5 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Baculoviridae
Recombinant Proteins
Antibodies
Systemic Scleroderma

Frequency of autoantibodies to a major epitope on the carboxyl terminal fragment of CENP-B in patients with autoimmune disease

Whyte, J., Soriano, E., Earnshaw, W. C. & McHugh, N. J., 5 May 1995, In : British Journal of Rheumatology. 34, 5, p. 407-412 6 p.

Research output: Contribution to journalArticle

Centromere
Autoantibodies
Autoimmune Diseases
Epitopes
Anti-Idiotypic Antibodies

Proton magnetic resonance spectroscopy of systemic lupus erythematosus involving the central nervous system

Davie, C. A., Feinstein, A., Kartsounis, L. D., Barker, G. J., McHugh, N. J., Walport, M. J., Ron, M. A., Moseley, I. F., McDonald, W. I. & Miller, D. H., 1 Aug 1995, In : The Journal of Comparative Neurology. 242, 8, p. 522-528 7 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Central Nervous System
Psychiatry
Magnetic Resonance Imaging
Creatine

Segregation of autoantibodies with disease in monozygotic twin pairs discordant for systemic sclerosis. Three further cases

McHugh, N. J., Harvey, G. R., Whyte, J. & Dorsey, J. K., Dec 1995, In : Arthritis & Rheumatism. 38, 12, p. 1845-1850 6 p.

Research output: Contribution to journalArticle

Diseases in Twins
Monozygotic Twins
Systemic Scleroderma
Autoantibodies
Major Histocompatibility Complex
1994

Anti-centromere antibodies (ACA) in systemic sclerosis patients and their relatives: a serological and HLA study

McHugh, N. J., Whyte, J., Artlett, C., Briggs, D. C., Stephens, C. O., Olsen, N. J., Gusseva, N. G., Maddison, P. J., Black, C. M. & Welsh, K., May 1994, In : Clinical And Experimental Immunology. 96, 2, p. 267-274 8 p.

Research output: Contribution to journalArticle

Centromere
Systemic Scleroderma
Anti-Idiotypic Antibodies
HLA-DRB1 Chains
Siblings

Anti-topoisomerase I antibodies in silica-associated systemic sclerosis. A model for autoimmunity

McHugh, N. J., Whyte, J., Harvey, G. & Haustein, U. F., Aug 1994, In : Arthritis & Rheumatism. 37, 8, p. 1198-1205 8 p.

Research output: Contribution to journalArticle

Type I DNA Topoisomerase
Systemic Scleroderma
Autoimmunity
Silicon Dioxide
Antibodies

Familial scleroderma--evidence for environmental versus genetic trigger

Stephens, C. O., Briggs, D. C., Whyte, J., Artlett, C. M., Scherbakov, A. B., Olsen, N., Gusseva, N. G., McHugh, N. J., Maddison, P. J. & Welsh, K. I., 12 Dec 1994, In : British Journal of Rheumatology. 33, 12, p. 1131-5 5 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Autoantibodies
Alleles
Immunogenetics
Histocompatibility Testing

Frequency and clinical associations of anti-chromo antibodies in connective tissue disease

Soriano, E., Whyte, J. & McHugh, N. J., 1994, In : Annals of the Rheumatic Diseases. 53, 10, p. 666-670 5 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Centromere
Anti-Idiotypic Antibodies
Tissue
Antibodies

HLA-DQB1 associations with anti-topoisomerase-1 antibodies in patients with systemic sclerosis and their first degree relatives

Whyte, J., Artlett, C., Harvey, G., Stephens, C. O., Welsh, K., Black, C., Maddison, P. J. & McHugh, N. J., Aug 1994, In : Journal of Autoimmunity. 7, 4, p. 509-520 12 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Antibodies
HLA-DRB1 Chains
Alleles
K562 Cells

Lupus-like syndrome associated with the use of minocycline

Quilty, B. & McHugh, N., Dec 1994, In : British Journal of Rheumatology. 33, 12, p. 1197-1198 2 p.

Research output: Contribution to journalArticle

Psoriatic arthritis: outcome of disease subsets and relationship of joint disease to nail and skin disease

Jones, S. M., Armas, J. B., Cohen, M. G., Lovell, C. R., Evison, G. & McHugh, N. J., 1994, In : British Journal of Rheumatology. 33, 9, p. 834-839 6 p.

Research output: Contribution to journalArticle

Nail Diseases
Psoriatic Arthritis
Joint Diseases
Skin Diseases
Arthritis

Subgroups in psoriatic arthritis

Jones, S. M. & McHugh, N. J., 8 Aug 1994, In : British Journal of Rheumatology. 33, 8, p. 789

Research output: Contribution to journalArticle

Systemic sclerosis: HLA antigens, autoantibodies and the brain

McHugh, N. J., 1994, In : British Journal of Rheumatology. 33, 4, p. 305-306 2 p.

Research output: Contribution to journalArticle

The association of primary biliary cirrhosis and systemic sclerosis is not accounted for by cross reactivity between mitochondrial and centromere antigens

Whyte, J., Hough, D., Maddison, P. J. & McHugh, N. J., Jun 1994, In : Journal of Autoimmunity. 7, 3, p. 413-424 12 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Centromere
Systemic Scleroderma
Antigens
Antibodies

The cervical spine in psoriatic arthritis: a clinical and radiological study

Jenkinson, T., Armas, J., Evison, G., Cohen, M., Lovell, C. & McHugh, N. J., 1994, In : British Journal of Rheumatology. 33, 3, p. 255-259 5 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Spine
Spondylitis
Ankylosis
Nails
1993

Anticardiolipin antibodies in ischaemic heart disease

Edwards, T., Thomas, R. D. & McHugh, N. J., 16 Oct 1993, In : Lancet. 342, 8877, p. 989

Research output: Contribution to journalArticle

A prospective study of pregnancy outcome in women screened at a routine antenatal clinic for anticardiolipin antibodies

Stuart, R. A., Kornman, L. H. & McHugh, N. J., Jul 1993, In : British Journal of Obstetrics and Gynaecology. 100, 6, p. 599-600 2 p.

Research output: Contribution to journalArticle

Combined corticosteroid and aspirin treatment for the high risk lupus pregnancy

Stuart, R. A., Quinn, M. J. & McHugh, N. J., Jun 1993, In : British Journal of Obstetrics and Gynaecology. 100, 6, p. 601-602 2 p.

Research output: Contribution to journalArticle

Connective tissue disease and autoantibodies in the kindreds of 63 patients with systemic sclerosis

Maddison, P. J., Stephens, C., Briggs, D., Welsh, K. I., Harvey, G., Whyte, J., McHugh, N. & Black, C. M., Mar 1993, In : Medicine. 72, 2, p. 103-112 10 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Systemic Scleroderma
Autoantibodies
HLA-DR5 Antigen
HLA-DR3 Antigen

Elevated anticardiolipin antibodies in a patient with vibration-white-finger, valvular heart disease and psoriatic arthritis

McHugh, N. J., Elvins, D. M. & Ring, E. F., Mar 1993, In : Clinical Rheumatology. 12, 1, p. 70-73 4 p.

Research output: Contribution to journalArticle

Anticardiolipin Antibodies
Heart Valve Diseases
Psoriatic Arthritis
Vibration
Fingers
1992

Atypical Behçet's disease with peripheral erosive arthropathy and pyoderma gangrenosum

Armas, J. B., Davies, J., Davis, M., Lovell, C. & McHugh, N., 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 177-180 4 p.

Research output: Contribution to journalArticle

Pyoderma Gangrenosum
Behcet Syndrome
Joint Diseases
Inflammatory Bowel Diseases
Ulcer

Spontaneous neutrophil activation in patients with primary Raynaud's phenomenon and systemic sclerosis

Stevens, T. R., Hall, N. D., McHugh, N. J. & Maddison, P. J., 12 Dec 1992, In : Rheumatology. 31, 12, p. 856

Research output: Contribution to journalArticle

1991

HLA class II restriction of autoantibody production in patients with systemic lupus erythematosus

Stephens, H. A., McHugh, N. J., Maddison, P. J., Isenberg, D. A., Welsh, K. I. & Panayi, G. S., 1991, In : Immunogenetics. 33, 4, p. 276-80 5 p.

Research output: Contribution to journalArticle

Lupus anticoagulant: clinical significance in anticardiolipin positive patients with systemic lupus erythematosus

McHugh, N. J., Moye, D. A., James, I. E., Sampson, M. & Maddison, P. J., 1991, In : Annals of the Rheumatic Diseases. 50, 8, p. 548-52 5 p.

Research output: Contribution to journalArticle

Lupus Coagulation Inhibitor
Anticardiolipin Antibodies
Systemic Lupus Erythematosus
Immunoglobulin G
Phosphatidylethanolamines
1990

Anticardiolipin and antineutrophil antibodies in giant cell arteritis

McHugh, N. J., James, I. E. & Plant, G. T., 1990, In : Journal of Rheumatology. 17, 7, p. 916-922 7 p.

Research output: Contribution to journalArticle

Anticardiolipin Antibodies
Giant Cell Arteritis
Antineutrophil Cytoplasmic Antibodies
Immunoglobulin G
Polymyalgia Rheumatica

Arthropathy of hands and feet in systemic lupus erythematosus

Reilly, P. A., Evison, G., McHugh, N. J. & Maddison, P. J., Jun 1990, In : Journal of Rheumatology. 17, 6, p. 777-784 8 p.

Research output: Contribution to journalArticle

Joint Diseases
Systemic Lupus Erythematosus
Foot
Hand
Hand Deformities

Autoantibodies to mitochondrial and centromere antigens in primary biliary cirrhosis and systemic sclerosis

McHugh, N. J., James, I. E., Fairburn, K. & Maddison, P. J., 1990, In : Clinical And Experimental Immunology. 81, 2, p. 244-9 6 p.

Research output: Contribution to journalArticle

Biliary Liver Cirrhosis
Centromere
Systemic Scleroderma
Autoantibodies
Antigens

Clinical significance of antibodies to a 68 kDa U1RNP polypeptide in connective tissue disease

McHugh, N., James, I. & Maddison, P., 1990, In : Journal of Rheumatology. 17, 10, p. 1320-1328 9 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Systemic Lupus Erythematosus
Mixed Connective Tissue Disease
Peptides
Antibodies

Pregnancy loss, menopause, and the onset of rheumatoid arthritis

McHugh, N. J., 1990, In : Annals of the Rheumatic Diseases. 49, 10, p. 817-818 2 p.

Research output: Contribution to journalArticle

1989

HLA-DR antigens and anticardiolipin antibodies in patients with systemic lupus erythematosus

McHugh, N. J. & Maddison, P. J., 1989, In : Arthritis & Rheumatism. 32, 12, p. 1623-1624 2 p.

Research output: Contribution to journalArticle

Pregnancy outcome and autoantibodies in connective tissue disease

McHugh, N. J., Reilly, P. A. & McHugh, L. A., Jan 1989, In : The Journal of Rheumatology. 16, 1, p. 42-6 5 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Pregnancy Outcome
Autoantibodies
Systemic Lupus Erythematosus
Systemic Scleroderma

Reflex sympathetic dystrophy associated with squamous cell carcinoma of the lung

Prowse, M., Higgs, C. M., Forrester-Wood, C. & McHugh, N., Apr 1989, In : Annals of the Rheumatic Diseases. 48, 4, p. 339-341 3 p.

Research output: Contribution to journalArticle

Reflex Sympathetic Dystrophy
Tumors
Squamous Cell Carcinoma
Paraneoplastic Syndromes
Lung

The effect of pregnancy on the onset of psoriatic arthritis

McHugh, N. J. & Laurent, M. R., 1989, In : British Journal of Rheumatology. 28, 1, p. 50-2 3 p.

Research output: Contribution to journalArticle

Psoriatic Arthritis
Arthritis
Pregnancy
Psoriasis
Hormones
1988

Anticardiolipin antibodies, livedo reticularis, and major cerebrovascular and renal disease in systemic lupus erythematosus

McHugh, N. J., Maymo, J., Skinner, R. P., James, I. & Maddison, P. J., Feb 1988, In : Annals of the Rheumatic Diseases. 47, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

Livedo Reticularis
Cerebrovascular Disorders
Anticardiolipin Antibodies
Systemic Lupus Erythematosus
Immunoglobulin G

Development and assessment of a computerized index of clinical disease activity in systemic lupus erythematosus

Symmons, D. P. M., Coppock, J. S., Bacon, P. A., Bresnihan, B., Isenberg, D. A., Maddison, P., McHugh, N., Snaith, M. L. & Zoma, A. S., Nov 1988, In : The Quarterly Journal of Medicine. 69, 258, p. 927-937 11 p.

Research output: Contribution to journalArticle

Systemic Lupus Erythematosus
Ireland
Multicenter Studies
Databases
Physicians

Differential isotype recognition of two centromere associated polypeptides by immunoblotting in connective tissue disease

McHugh, N. J., James, I. E. & Maddison, P. J., Jun 1988, In : Clinical And Experimental Immunology. 72, 3, p. 457-64 8 p.

Research output: Contribution to journalArticle

Connective Tissue Diseases
Centromere
Immunoblotting
Peptides
Serum

Infusion of iloprost, a prostacyclin analogue, for treatment of Raynaud's phenomenon in systemic sclerosis

McHugh, N. J., Csuka, M., Watson, H., Belcher, G., Amadi, A., Ring, E. F., Black, C. M. & Maddison, P. J., 1988, In : Annals of the Rheumatic Diseases. 47, 1, p. 43-47 5 p.

Research output: Contribution to journalArticle

Iloprost
Raynaud Disease
Systemic Scleroderma
Epoprostenol
Placebos