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Research Output

2009

Myositis-specific autoantibodies: their clinical and pathogenic significance in disease expression

Gunawardena, H., Betteridge, Z. E. & McHugh, N. J., 2009, In : Rheumatology. 48, 6, p. 607-612 6 p.

Research output: Contribution to journalArticle

198 Citations (Scopus)

Numerical scoring for the Classic BILAG index

Cresswell, L., Yee, C. S., Farewell, V., Rahman, A., Teh, L. S., Griffiths, B., Bruce, I. N., Ahmad, Y., Prabu, A., Akil, M., McHugh, N. J., Toescu, V., D'Cruz, D., Khamashta, M. A., Maddison, P., Isenberg, D. A. & Gordon, C., 2009, In : Rheumatology. 48, 12, p. 1548-1552 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Pathogenic mechanisms of disease in myositis: autoantigens as clues

Betteridge, Z. E., Gunawardena, H. & McHugh, N. J., 2009, In : Current Opinion in Rheumatology. 21, 6, p. 604-9 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

The BILAG-2004 index is sensitive to change for assessment of SLE disease activity

Yee, C. S., Farewell, V., Isenberg, D. A., Griffiths, B., Teh, L. S., Bruce, I. N., Ahmad, Y., Rahman, A., Prabu, A., Akil, M., McHugh, N. J., Edwards, C., D'Cruz, D., Khamashta, M. A., Maddison, P. & Gordon, C., 2009, In : Rheumatology. 48, 6, p. 691-695 5 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

Traditional schemes for treatment of psoriatic arthritis

McHugh, N. J., 2009, In : Journal of Rheumatology. 83, Suppl, p. 49-51 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Treatment recommendations for psoriatic arthritis

Ritchlin, C. T., Kavanaugh, A., Gladman, D. D., Mease, P. J., Helliwell, P., Boehncke, W-H., de Vlam, K., Fiorentino, D., FitzGerald, O., Gottlieb, A. B., McHugh, N. J., Nash, P., Qureshi, A. A., Soriano, E. R. & Taylor, W. J., Sep 2009, In : Annals of the Rheumatic Diseases. 68, 9, p. 1387-1394 8 p.

Research output: Contribution to journalArticle

371 Citations (Scopus)
2008

Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus.

Chan, M. T., Owen, P., Dunphy, J., Cox, B., Carmichael, C., Korendowych, E. & McHugh, N. J., 2008, In : Journal of Rheumatology. 35, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

BILAG-2004 index captures systemic lupus erythematosus disease activity better than SLEDAI-2000

Yee, C. S., Isenberg, D. A., Prabu, A., Sokoll, K., Teh, L. S., Rahman, A., Bruce, I. N., Griffiths, B., Akil, M., McHugh, N. J., D'Cruz, D., Khamashta, M. A., Maddison, P., Zoma, A. & Gordon, C., 2008, In : Annals of the Rheumatic Diseases. 67, 6, p. 873-876 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Clinical associations of autoantibodies to a p155/140 kDa doublet protein in juvenile dermatomyositis

Gunawardena, H., Wedderburn, L. R., North, J., Betteridge, Z., Dunphy, J., Chinoy, H., Davidson, J. E., Cooper, R. G., McHugh, N. J. & Juvenile Dermatomy Res Grp, U. K., Mar 2008, In : Rheumatology. 47, 3, p. 324-328 5 p.

Research output: Contribution to journalArticle

157 Citations (Scopus)

Drug use and toxicity in psoriatic disease: Focus on methotrexate

Taylor, W. J., Korendowych, E., Nash, P., Helliwell, P. S., Choy, E., Krueger, G. G., Soriano, E. R., McHugh, N. J. & Rosen, C. F., Jul 2008, In : Journal of Rheumatology. 35, 7, p. 1454-1457 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Features and recommended treatment of systemic sclerosis

Gunawardena, H. & McHugh, N. J., 2008, In : Prescriber. 19, 18, p. 59-65 7 p.

Research output: Contribution to journalArticle

Newly identified autoantibodies: relationship to idiopathic inflammatory myopathy subsets and pathogenesis

Gunawardena, H., Betteridge, Z. E. & McHugh, N. J., 2008, In : Current Opinion in Rheumatology. 20, 6, p. 675-680 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Pulmonary artery hypertension as the presenting feature of systemic sclerosis sine scleroderma

Pauling, J. D., Gunawardena, H., Coghlan, J. G., Easaw, J., Suntharalingam, J. & McHugh, N. J., Sep 2008, In : Rheumatology. 47, 9, p. 1431-1432 2 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

The Protein Tyrosine Phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British caucasian patients

Chinoy, H., Platt, H., Lamb, J. A., Betteridge, Z., Gunawardena, H., Fertig, N., Varsani, H., Davidson, J., Oddis, C. V., McHugh, N. J., Wedderburn, L. R., Ollier, W. E. R. & Cooper, R. G., 2008, In : Arthritis & Rheumatism. 58, 10, p. 3247-3254 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2007

Anti-synthetase syndrome: a new autoantibody to phenylalanyl transfer RNA synthetase (anti-Zo) associated with polymyositis and interstitial pneumonia

Betteridge, Z., Gunawardena, H., North, J., Slinn, J. & McHugh, N. J., 27 Mar 2007, In : Rheumatology. 46, 6, p. 1005-1008 4 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

A polymorphism in the CTGF promoter region associated with systemic sclerosis

Fonseca, C., Lindahl, G. E., Ponticos, M., Sestini, P., Renzoni, E. A., Holmes, A. M., Spagnolo, P., Pantelidis, P., Leoni, P., McHugh, N. J., Stock, C. J., Shi-Wen, X., Denton, C. P., Black, C. M., Welsh, K. I., du Bois, R. M. & Abraham, D. J., 2007, In : The New England Journal of Medicine. 357, 12, p. 1210-1220 11 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

British Isles Lupus Assessment Group 2004 index is valid for assessment of disease activity in systemic lupus erythematosus

Yee, C-S., Farewell, V., Isenberg, D. A., Rahman, A., Teh, L-S., Griffiths, B., Bruce, I. N., Ahmad, Y., Prabu, A., Akil, M., McHugh, N. J., D'Cruz, D., Khamashta, M. A., Maddison, P. & Gordon, C., 2007, In : Arthritis & Rheumatism. 56, 12, p. 4113-4119 7 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)

Centromere autoantibodies

John McHugh, N., 1 Dec 2007, Autoantibodies. Shoenfeld, Y. & Gerschwin, M. E. (eds.). Elsevier Academic Press Inc, p. 151-157 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Clinical outcome measures in psoriatic arthritis

Kavanaugh, A. & McHugh, N., 1 Dec 2007, Psoriatic and Reactive Arthritis: A Companion to Rheumatology. Ritchlin, C. T. (ed.). Philadelphia, U. S. A.: Elsevier Academic Press Inc, p. 90-96 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Conventional therapy of psoriatic arthritis: evidence-based review

McHugh, N. J. & Soriano, E. R., 2007, In : Reumatismo. 59, Suppl 1, p. 81-84 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositis-scleroderma overlap

Wedderburn, L. R., McHugh, N. J., Chinoy, H., Cooper, R. G., Salway, F., Ollier, W. E. R., McCann, L. J., Varsani, H., Dunphy, J., North, J. & Davidson, J. E., 2007, In : Rheumatology. 46, 12, p. 1786-1791 6 p.

Research output: Contribution to journalArticle

78 Citations (Scopus)

Identification of a novel autoantibody directed against small ubiquitin-like modifier activating enzyme in dermatomyositis

Betteridge, Z., Gunawardena, H., North, J., Slinn, J. & McHugh, N. J., 1 Sep 2007, In : Arthritis & Rheumatism. 56, 9, p. 3132-3137 6 p.

Research output: Contribution to journalArticle

97 Citations (Scopus)

Improvement in patient-reported outcomes for patients with ankylosing spondylitis treated with etanercept 50 mg once-weekly and 25 mg twice-weekly

Braun, J., McHugh, N. J., Singh, A., Wajdula, J. S. & Sato, R., 2007, In : Rheumatology. 46, 6, p. 999-1004 6 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)

Maximum blood flow and microvascular regulatory responses in systemic sclerosis

Gunawardena, H., Harris, N. D., Carmichael, C. & McHugh, N. J., 2007, In : Rheumatology. 46, 7, p. 1079-1082 4 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Microvascular responses following digital thermal hyperaemia and iontophoresis measured by laser Doppler imaging in idiopathic inflammatory myopathy

Gunawardena, H., Harris, N. D., Carmichael, C. & McHugh, N. J., 2007, In : Rheumatology. 46, 9, p. 1483-1486 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Prevention of vascular damage in scleroderma and autoimmune Raynaud's phenomenon: a multicenter, randomized, double-blind, placebo-controlled trial of the angiotensin-converting enzyme inhibitor quinapril

Gliddon, A. E., Doré, C. J., Black, C. M., McHugh, N. J., Moots, R., Denton, C. P., Herrick, A., Barnes, T., Camilleri, J., Chakravarty, K., Emery, P., Griffiths, B., Hopkinson, N. D., Hickling, P., Lanyon, P., Laversuch, C., Lawson, T., Mallya, R., Nisar, M., Rhys-Dillon, C. & 2 others, Sheeran, T. & Maddison, P. J., 2007, In : Arthritis & Rheumatism. 56, 11, p. 3837-46 10 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)
2006

A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma

Hoyles, R. K., Ellis, R. W., Wellsbury, J., Lees, B., Newlands, P., Goh, N. S. L., Roberts, C., Desai, S., Herrick, A. L., McHugh, N. J., Foley, N. M., Pearson, S. B., Emery, P., Veale, D. J., Denton, C. P., Wells, A. U., Black, C. M. & du Bois, R. M., Dec 2006, In : Arthritis & Rheumatism. 54, 12, p. 3962-3970 9 p.

Research output: Contribution to journalArticle

466 Citations (Scopus)

A polymorphism in the promoter region of the CD86 (B7.2) gene is associated with systemic sclerosis

Abdallah, A. M., Renzoni, E. A., Anevlavis, S., Lagan, A. L., Munkonge, F. M., Fonseca, C., Black, C. M., Briggs, D., Wells, A. U., Marshall, S. E., McHugh, N., du Bois, R. M. & Welsh, K. I., Jun 2006, In : International journal of immunogenetics. 33, 3, p. 155-161 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Clinical Image: skin hyperpigmentation over inflamed joints

Ostroumova, M. A., Lovell, C. R., McHugh, N. J. & Mann, R. J., Aug 2006, In : Arthritis & Rheumatism. 54, 8, p. 2604

Research output: Contribution to journalArticle

Developing classification criteria for peripheral joint psoriatic arthritis. Step I. Establishing whether the rheumatologist's opinion on the diagnosis can be used as the 'gold standard'

Symmons, D. P. M., Lunt, M., Watkins, G., Helliwell, P., Jones, S., McHugh, N. & Veale, D., 2006, In : Journal of Rheumatology. 33, 3, p. 552-557 6 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Endothelin axis polymorphisms in patients with scleroderma

Fonseca, C., Renzoni, E., Sestini, P., Pantelidis, P., Lagan, A., Bunn, C., McHugh, N., Welsh, K. I., Du Bois, R. M., Denton, C. P., Black, C. & Abraham, D., Sep 2006, In : Arthritis & Rheumatism. 54, 9, p. 3034-3042 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study

Cunninghame Graham, D. S., Wong, A. K., McHugh, N. J., Whittaker, J. C. & Vyse, T. J., 1 Nov 2006, In : Human Molecular Genetics. 15, 21, p. 3195-3205 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Influence of clinical features on the health status of patients with limited cutaneous systemic sclerosis

Gliddon, A. E., Doré, C. J., Maddison, P. J., Barnes, T., Black, C., Borg, A., Camilleri, J., Chakravarty, K., Denton, C., Emery, P., Griffiths, B., Herrick, A., Hopkinson, N., Hickling, P., Lanyon, P., Laversuch, C., Lawson, T., Mallya, R., McHugh, N., Moots, R. & 3 others, Nisar, M., Rhys-Dillon, C. & Sheeran, T., 15 Jun 2006, In : Arthritis Care and Research. 55, 3, p. 473-479 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

MHC class II, tumour necrosis factor alpha, and lymphotoxin alpha gene haplotype associations with serological subsets of systemic lupus erythematosus

McHugh, N. J., Owen, P., Cox, B., Dunphy, J. & Welsh, K., Apr 2006, In : Annals of the Rheumatic Diseases. 65, 4, p. 488-494 7 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Other seronegative spondyloarthropathies

McHugh, N. J., 1 Oct 2006, In : Medicine. 34, 10, p. 401-404 4 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Revised British Isles Lupus Assessment Group 2004 index: a reliable tool for assessment of systemic lupus erythematosus activity

Yee, C-S., Farewell, V., Isenberg, D. A., Prabu, A., Sokoll, K., Teh, L-S., Rahman, A., Bruce, I. N., Griffiths, B., Akil, M., McHugh, N., D'Cruz, D., Khamashta, M. A., Bowman, S., Maddison, P., Zoma, A., Allen, E., Gordon, C. & British Isles Lupus Assessment Group, Oct 2006, In : Arthritis & Rheumatism. 54, 10, p. 3300-3305 6 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)

Systematic review of treatments for psoriatic arthritis: An evidence based approach and basis for treatment guidelines

Kavanaugh, A. F., Ritchlin, C. T., Boehncke, W. H., Cassell, S., Gladman, D. D., Gottlieb, A. B., Helliwell, P., Krueger, G., McHugh, N. J., Mease, P. J., Menon, K., Nash, P., Prinz, J., Rzany, B., Siu, K., Soriano, E. R. & Strober, B. E., 1 Jul 2006, In : Journal of Rheumatology. 33, 7, p. 1417-1421 5 p.

Research output: Contribution to journalReview article

126 Citations (Scopus)

Therapies for peripheral joint disease in psoriatic arthritis. A systematic review

Soriano, E. R. & McHugh, N. J., 2006, In : Journal of Rheumatology. 33, 7, p. 1422-1430 9 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)
2005

BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus

Isenberg, D. A., Rahman, A., Allen, E., Farewell, V., Akil, M., Bruce, I. N., D'Cruz, D., Griffiths, B., Khamashta, M., Maddison, P., McHugh, N., Snaith, M., Teh, L. S., Yee, C. S., Zoma, A. & Gordon, C., 2005, In : Rheumatology. 44, 7, p. 902-906 5 p.

Research output: Contribution to journalArticle

293 Citations (Scopus)

British Association of Dermatologists guidelines for use of biological interventions in psoriasis 2005

Smith, C. H., Anstey, A. V., Barker, J. N. W. N., Burden, A. D., Chalmers, R. J. G., Chandler, D., Finlay, A. Y., Griffiths, C. E. M., Grifitths, C. E. M., Jackson, K., McHugh, N. J., McKenna, K. E., Reynolds, N. J., Ormerod, A. D. & British Association of Dermatologists, Sep 2005, In : British Journal of Dermatology. 153, 3, p. 486-497 12 p.

Research output: Contribution to journalArticle

260 Citations (Scopus)

Genetic factors in psoriatic arthritis

Korendowych, E. & McHugh, N., 1 Jul 2005, In : Current Rheumatology Reports. 7, 4, p. 306-312 7 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Guideline for anti-TNF-α therapy in psoriatic arthritis

Kyle, S., Chandler, D., Griffiths, C. E. M., Helliwell, P., Lewis, J., McInnes, I., Oliver, S., Symmons, D., McHugh, N. & British Society for Rheumatology Standards Guidelines Audit Working Group (SGAWG), 2005, In : Rheumatology. 44, 3, p. 390-397 8 p.

Research output: Contribution to journalArticle

111 Citations (Scopus)

Joint and soft tissue injections: a survey of general practitioners

Liddell, W. G., Carmichael, C. R. & McHugh, N. J., 8 Aug 2005, In : Rheumatology. 44, 8, p. 1043-1046 4 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The clinical and genetic associations of anti-cyclic citrullinated peptide antibodies in psoriatic arthritis

Korendowych, E., Owen, P., Ravindran, J., Carmichael, C. & McHugh, N., Aug 2005, In : Rheumatology. 44, 8, p. 1056-1060 5 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
2004

A qualitative investigation into the impact of group education upon participants’ management of their disease in lupus and scleroderma

Brown, SJ., Somerset, ME., McCabe, CS. & McHugh, N. J., 2004, In : Musculoskeletal Care. 2, 4, p. 207-217 11 p.

Research output: Contribution to journalArticle

Auto-antibody testing in obstetric patients

Tikly, M. & McHugh, N., 2004, In : South African Medical Journal. 94, 7, p. 498

Research output: Contribution to journalLetter

Human leukocyte antigen class II associations with systemic sclerosis in South Africans

Tikly, M., Rands, A., McHugh, N., Wordsworth, P. & Welsh, K., May 2004, In : Tissue Antigens. 63, 5, p. 487-490 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Interleukin 1α, interleukin 1β and interleukin 1 receptor gene polymorphisms in psoriatic arthritis

Ravindran, J. S., Owen, P., Lagan, A., Lewis, J., Korendowych, E., Welsh, K. & McHugh, N., 2004, In : Rheumatology. 43, 1, p. 22-26 5 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)
2003

Non organ based laboratory markers in systemic sclerosis

McHugh, N. J., Distler, O., Giacomelli, R. & Riemekasten, G., 2003, In : Clinical and Experimental Rheumatology. 21, 3 Suppl 29, p. S32-38

Research output: Contribution to journalArticle

42 Citations (Scopus)

Progression of peripheral joint disease in psoriatic arthritis: a 5-yr prospective study

McHugh, N. J., Balachrishnan, C. & Jones, S. M., 6 Jun 2003, In : Rheumatology. 42, 6, p. 778-783 6 p.

Research output: Contribution to journalArticle

235 Citations (Scopus)