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Research Output

2012

European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies.

Gossec, L., Smolen, J. S., Gaujoux-Viala, C., Ash, Z., Marzo-Ortega, H., van der Heijde, D., Fitzgerald, O., Aletaha, D., Balint, P., Boumpas, D., Braun, J., Breedveld, F. C., Burmester, G., Cañete, J. D., de Wit, M., Dagfinrud, H., de Vlam, K., Dougados, M., Helliwell, P., Kavanaugh, A. & 15 others, Kvien, T. K., Landewé, R., Luger, T., Maccarone, M., McGonagle, D., McHugh, N. J., McInnes, I. B., Ritchlin, C., Sieper, J., Tak, P. P., Valesini, G., Vencovsky, J., Winthrop, K. L., Zink, A. & Emery, P., Jan 2012, In : Annals of the Rheumatic Diseases. 71, 1, p. 4-12 9 p.

Research output: Contribution to journalArticle

331 Citations (Scopus)
3 Citations (Scopus)

Genetic association study of NF-κB genes in UK Caucasian adult and juvenile onset idiopathic inflammatory myopathy

Chinoy, H., Li, C. K-C., Platt, H., Fertig, N., Varsani, H., Gunawardena, H., Betteridge, Z., Oddis, C. V., McHugh, N. J., Wedderburn, L. R., Ollier, W. E. R., Cooper, R. G. & UK Adult Onset Myositis Immunogenetic Consortium and UK Juvenile Dermatomyositis Research Group, May 2012, In : Rheumatology. 51, 5, p. 794-799 6 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Interaction of HLA-DRB1*03 and smoking for the development of anti-Jo-1 antibodies in adult idiopathic inflammatory myopathies: a European-wide case study.

Chinoy, H., Adimulam, S., Marriage, F., New, P., Vincze, M., Zilahi, E., Kapitány, A., Gyetvai, A., Ekholm, L., Novota, P., Remakova, M., Charles, P., McHugh, N. J., Padyukov, L., Alfredsson, L., Vencovsky, J., Lundberg, I. E., Danko, K., Ollier, W. E. & Cooper, R. G., Jun 2012, In : Annals of the Rheumatic Diseases. 71, 6, p. 961-965 5 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

Investigation of IL1, VEGF, PPARG and MEFV genes in psoriatic arthritis susceptibility

Bowes, J., Ho, P., Flynn, E., Salah, S., McHugh, N. J., Fitzgerald, O., Packham, J., Morgan, A. W., Helliwell, P. S., Bruce, I. N. & Barton, A., 2012, In : Annals of the Rheumatic Diseases. 71, p. 313-314 2 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Joint count reliability in psoriatic arthritis observational trials: an unreported problem

Tillett, W., Shaddick, G., Korendowych, E., De Vries, C. S. & McHugh, N., 2012, In : Rheumatology. 51, 7, p. 1333-1334

Research output: Contribution to journalArticle

File
4 Citations (Scopus)
109 Downloads (Pure)

Mortality and causes of death in psoriatic arthritis

Arumugam, R. & McHugh, N. J., Jul 2012, In : Journal of Rheumatology. Supplement 89, p. 32-35 4 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Predictors of health-related quality of life and fatigue in systemic sclerosis: evaluation of the EuroQol-5D and FACIT-F assessment tools

Strickland, G., Pauling, J., Cavill, C. & McHugh, N., Aug 2012, In : Clinical Rheumatology. 31, 8, p. 1215-1222 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The BILAG-2004 systems tally: a novel way of representing the BILAG-2004 index scores longitudinally

Yee, C-S., Gordon, C., Isenberg, D. A., Griffiths, B., Teh, L-S., Bruce, I. N., Ahmad, Y., Rahman, A., Prabu, A., Akil, M., McHugh, N., Edwards, C., D'Cruz, D., Khamashta, M. A. & Farewell, V. T., 2012, In : Rheumatology. 51, 11, p. 2099-2105 7 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The ClASsification for Psoriatic ARthritis (CASPAR) criteria - A retrospective feasibility, sensitivity, and specificity study

Tillett, W., Costa, L., Jadon, D., Wallis, D., Cavill, C., McHugh, J., Korendowych, E. & McHugh, N. J., Jan 2012, In : Journal of Rheumatology. 39, 1, p. 154-156 3 p.

Research output: Contribution to journalArticle

58 Citations (Scopus)

The clinical aspects of autoantibodies

Paulin, J. D. & McHugh, N., 1 Jan 2012, Scleroderma: From Pathogenesis to Comprehensive Management. Varga, J., Denton, C. P. & Wigley, F. M. (eds.). New York: Springer, p. 209-225 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

'To suddenly have a name for this thing... was wonderful': The patient's experience of receiving a diagnosis of systemic lupus erythematosus

Waldron, N., Brown, S. J., Elliott, B., Mchugh, N., Mccabe, C. S. & Hewlett, S., 1 Sep 2012, In : Musculoskeletal Care. 10, 3, p. 135-141 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Treatment algorithms for early psoriatic arthritis: Do they depend on disease phenotype?

Tillett, W. & McHugh, N., 1 Aug 2012, In : Current Rheumatology Reports. 14, 4, p. 334-342 9 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Use of infrared thermography as an endpoint in therapeutic trials of Raynaud's phenomenon and systemic sclerosis

Pauling, J. D., Shipley, J. A., Harris, N. D. & McHugh, N. J., 1 May 2012, In : Clinical and Experimental Rheumatology. 30, Supplement 71, p. S103-S115

Research output: Contribution to journalArticle

32 Citations (Scopus)

Work disability in psoriatic arthritis: a systematic review

Tillett, W., De Vries, C. & McHugh, N. J., Feb 2012, In : Rheumatology. 51, 2, p. 275-283 9 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)
2011

Antinuclear antibodies and clinical associations in a British cohort with limited cutaneous systemic sclerosis

Gliddon, A. E., Dore, C. J., Dunphy, J., Betteridge, Z., McHugh, N. J. & Maddison, P. J., 2011, In : Journal of Rheumatology. 38, 4, p. 702-705 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Biologic Agents in Psoriasis: British Association of Dermatologists' Guidelines for Biologic Intervention for Psoriasis 2009

Smith, C. H., Anstey, A. V., Barker, J. N. W. N., Burden, A. D., Chalmers, R. J. G., Chandler, D. A., Finlay, A. Y., Griffiths, C. E. M., Jackson, K., McHugh, N. J., McKenna, K. E., Reynolds, N. J. & Ormerod, A. D., 21 Mar 2011, British Association of Dermatologists' Management Guidelines. Cox, N. H. & English, J. S. C. (eds.). Wiley-Blackwell, p. 230-262 33 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort

Bowes, J., Ho, P., Flynn, E., Ali, F., Marzo-Ortega, H., Coates, L. C., Warren, R. B., McManus, R., Ryan, A. W., Kane, D., Korendowych, E., McHugh, N. J., FitzGerald, O., Packham, J., Morgan, A. W., Bruce, I. N. & Barton, A., 2011, In : Annals of the Rheumatic Diseases. 71, p. 1350-1354

Research output: Contribution to journalArticle

27 Citations (Scopus)

Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis

Bowes, J., Orozco, G., Flynn, E., Ho, P., Brier, R., Marzo-Ortega, H., Coates, L., McManus, R., Ryan, A. W., Kane, D., Korendowych, E., McHugh, N. J., FitzGerald, O., Packham, J., Morgan, A. W., Bruce, I. N. & Barton, A., Sep 2011, In : Annals of the Rheumatic Diseases. 70, 9, p. 1641-1644 4 p.

Research output: Contribution to journalArticle

77 Citations (Scopus)

Development of a Disease Severity and Responder Index for Psoriatic Arthritis (PsA) - Report of the OMERACT 10 PsA Special Interest Group

Coates, L. C., Mumtaz, A., Helliwell, P. S., Mease, P. J., Callis-Duffin, K., Krueger, G. G., McHugh, N. J., Strand, V., Gladman, D. D. & Fitzgerald, O., Jul 2011, In : Journal of Rheumatology. 38, 7, p. 1496-1501 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

EUROQOL-reported health disability demonstrates reduced quality of life remaining constant over time in established psoriatic arthritis

Tillett, W., Cavill, C., Korendowych, E. & McHugh, N., 2011, In : Rheumatology. 50, Supplement 3, p. 138 1 p., 245.

Research output: Contribution to journalArticle

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris

Bowes, J., Eyre, S., Flynn, E., Ho, P., Salah, S., Warren, R. B., Marzo-Ortega, H., Coates, L., McManus, R., Ryan, A. W., Kane, D., Korendowych, E., McHugh, N. J., FitzGerald, O., Packham, J., Morgan, A. W., Griffiths, C. E. M., Bruce, I. N., Worthington, J. & Barton, A., Jun 2011, In : Annals of the Rheumatic Diseases. 70, 6, p. 1016-1019 4 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Identification of autoantibodies to a novel autoantigen protein complex (EIF3) in polymyositis patients

Betteridge, Z., Chinoy, H., Vencovsky, J., Cooper, R. G. & McHugh, N. J., Apr 2011, In : Rheumatology. 50, Supplement 3, p. 105-106 2 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
118 Downloads (Pure)

Novel autoantibodies and clinical phenotypes in adult and juvenile myositis

Betteridge, Z. E., Gunawardena, H. & McHugh, N. J., 2011, In : Arthritis Research & Therapy. 13, 2, 209.

Research output: Contribution to journalArticle

79 Citations (Scopus)

The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients

Yee, C. S., Farewell, V. T., Isenberg, D. A., Griffiths, B., Teh, L. S., Bruce, I. N., Ahmad, Y., Rahman, A., Prabu, A., Akil, M., McHugh, N. J., Edwards, C., D'Cruz, D., Khamashta, M. A. & Gordon, C., 2011, In : Rheumatology. 50, 5, p. 982-988 7 p.

Research output: Contribution to journalArticle

94 Citations (Scopus)

Tumor necrosis factor promoter polymorphism TNF*-857 is a risk allele for psoriatic arthritis independent of the PSORS1 locus

Giardina, E., Hüffmeier, U., Ravindran, J., Behrens, F., Lepre, T., McHugh, N. J., Korendowych, E., Burkhardt, H., Novelli, G. & Reis, A., Dec 2011, In : Arthritis & Rheumatism. 63, 12, p. 3801-3806 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Vacuum-assisted closure therapy: a novel treatment for wound healing in systemic sclerosis

Pauling, J., Brown, S. J., James, J., Shipley, J. A., Korendowych, E. & McHugh, N. J., Feb 2011, In : Rheumatology. 50, 2, p. 420-422 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

‘It's more scary not to know’: a qualitative study exploring the information needs of patients with systemic lupus erythematosus at the time of diagnosis

Waldron, N., Brown, S., Hewlett, S., Elliott, B., McHugh, N. J. & McCabe, C., Dec 2011, In : Musculoskeletal Care. 9, 4, p. 228-238 11 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2010

A modified Sharp score demonstrates disease progression in established psoriatic arthritis

Ravindran, J., Cavill, C., Balakrishnan, C., Jones, S. M., Korendowych, E. & McHugh, N. J., Jan 2010, In : Arthritis Care & Research. 62, 1, p. 86-91 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

Huffmeier, U., Uebe, S., Ekici, A. B., Bowes, J., Giardina, E., Korendowych, E., Juneblad, K., Apel, M., McManus, R., Ho, P., Bruce, I. N., Ryan, A. W., Behrens, F., Lascorz, J., Bohm, B., Traupe, H., Lohmann, J., Gieger, C., Wichmann, H. E., Herold, C. & 10 others, Steffens, M., Klareskog, L., Wienker, T. F., FitzGerald, O., Alenius, G. M., McHugh, N. J., Novelli, G., Burkhardt, H., Barton, A. & Reis, A., Nov 2010, In : Nature Genetics. 42, 11, p. 996-999 4 p.

Research output: Contribution to journalArticle

252 Citations (Scopus)

Composite measures in psoriatic arthritis: GRAPPA 2008

Gladman, D. D., Landewé, R., McHugh, N. J., Fitzgerald, O., Thaci, D., Coates, L., Mease, P. J., Qureshi, A. A., Krueger, G. G., Ritchlin, C. T., Kavanaugh, A. F. & Garg, A., 2010, In : Journal of Rheumatology. 37, 2, p. 453-461 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
3 Citations (Scopus)

Effectiveness of adalimumab in treating patients with active psoriatic arthritis and predictors of good clinical responses for arthritis, skin and nail lesions

Van den Bosch, F., Manger, B., Goupille, P., McHugh, N. J., Rodevand, E., Holck, P., van Vollenhoven, R. F., Leirisalo-Repo, M., FitzGerald, O., Kron, M., Frank, M., Kary, S. & Kupper, H., 2010, In : Annals of the Rheumatic Diseases. 69, 2, p. 394-399 6 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)
1 Citation (Scopus)

Mortality in psoriatic arthritis: a single-center study from the UK

Buckley, C., Cavill, C., Taylor, G., Kay, H., Waldron, N., Korendowych, E. & McHugh, N. J., Oct 2010, In : Journal of Rheumatology. 37, 10, p. 2141-2144 4 p.

Research output: Contribution to journalArticle

47 Citations (Scopus)

Numerical scoring for the BILAG-2004 index

Yee, C. S., Cresswell, L., Farewell, V., Rahman, A., Teh, L. S., Griffiths, B., Bruce, I. N., Ahmad, Y., Prabu, A., Akil, M., McHugh, N. J., D'Cruz, D., Khamashta, M. A., Isenberg, D. A. & Gordon, C., 2010, In : Rheumatology. 49, 9, p. 1665-1669 5 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Observational study of treatment outcome in early diffuse cutaneous systemic sclerosis

Herrick, A. L., Lunt, M., Whidby, N., Ennis, H., Silman, A., McHugh, N. J. & Denton, C. P., 2010, In : Journal of Rheumatology. 37, 1, p. 116-124 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Other seronegative spondyloarthropathies

McHugh, N. J., 1 Apr 2010, In : Medicine. 38, 4, p. 190-193 4 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Raynaud's phenomenon and macrocytic anaemia

Flower, V., Pauling, J. D., Shipley, J. A. & McHugh, N. J., 8 Dec 2010, In : BMJ. 341, c6011.

Research output: Contribution to journalArticle

Risk factors for clinical coronary heart disease in systemic lupus erythematosus: The Lupus and Atherosclerosis Evaluation of Risk (LASER) study

Haque, S., Gordon, C., Isenberg, D., Rahman, A., Lanyon, P., Bell, A., Emery, P., McHugh, N. J., Teh, L. S., Scott, D. G. I., Akil, M., Naz, S., Andrews, J., Griffiths, B., Harris, H., Youssef, H., McLaren, J., Toescu, V., Devakumar, V., Teir, J. & 1 others, Bruce, I. N., Feb 2010, In : Journal of Rheumatology. 37, 2, p. 322-329 8 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Vacuum assisted closure therapy: A novel treatment for refractory digital ulceration in systemic sclerosis

Brown, S., James, J., Pauling, J. D., Shipley, J. A., Korenodwych, E. & McHugh, N. J., 2010, In : Clinical and Experimental Rheumatology. 28, 2 Supp 58, p. S162-S163

Research output: Contribution to journalArticle

361 Citations (Scopus)

Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis

Bowes, J., Flynn, E., Ho, P., Aly, B., Morgan, A. W., Marzo-Ortega, H., Coates, L., McManus, R., Ryan, A. W., Kane, D., Korendowych, E., McHugh, N. J., FitzGerald, O., Packham, J., Bruce, I. N. & Barton, A., 2010, In : Annals of the Rheumatic Diseases. 69, 12, p. 2199-2203 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2009

Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis

Gunawardena, H., Wedderburn, L. R., Chinoy, H., Betteridge, Z. E., North, J., Ollier, W. E. R., Cooper, R. G., Oddis, C. V., Ramanan, A. V., Davidson, J. E. & McHugh, N. J., Jun 2009, In : Arthritis & Rheumatism. 60, 6, p. 1807-1814 8 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009

Smith, C. H., Anstey, A. V., Barker, J. N. W. N., Burden, A. D., Chalmers, R. J. G., Chandler, D. A., Finlay, A. Y., Griffiths, C. E. M., Jackson, K., McHugh, N. J., McKenna, K. E., Reynolds, N. J. & Ormerod, A. D., 2009, In : British Journal of Dermatology. 161, 5, p. 987-1019 33 p.

Research output: Contribution to journalArticle

355 Citations (Scopus)

Clinical and human leucocyte antigen class II haplotype associations of autoantibodies to small ubiquitin-like modifier enzyme, a dermatomyositis-specific autoantigen target, in UK Caucasian adult-onset myositis

Betteridge, Z. E., Gunawardena, H., Chinoy, H., North, J., Ollier, W. E. R., Cooper, R. G. & McHugh, N. J., Oct 2009, In : Annals of the Rheumatic Diseases. 68, 10, p. 1621-1625 5 p.

Research output: Contribution to journalArticle

102 Citations (Scopus)

HLA-DPB1 associations differ between DRB1*03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy

Chinoy, H., Payne, D., Poulton, K. V., Fertig, N., Betteridge, Z., Gunawardena, H., Davidson, J. E., Oddis, C. V., McHugh, N. J., Wedderburn, L. R., Ollier, W. E. & Cooper, R. G., 2009, In : Rheumatology. 48, 10, p. 1213-7 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

International multicenter psoriasis and psoriatic arthritis reliability trial for the assessment of skin, joints, nails, and dactylitis

Chandran, V., Gottlieb, A., Cook, R. J., Duffin, K. C., Garg, A., Helliwell, P., Kavanaugh, A., Krueger, G. G., Langley, R. G., Lynde, C., Mchugh, N. J., Mease, P., Olivieri, I., Rahman, P., Rosen, C. F., Salvarani, C., Thaci, D., Toloza, S. M. A., Wong, M. Y. W., Zhou, Q. M. & 1 others, Gladman, D. D., Sep 2009, In : Arthritis & Rheumatism. 61, 9, p. 1235-1242 8 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)

Lack of agreement between rheumatologists in defining digital ulceration in systemic sclerosis

Herrick, A. L., Roberts, C., Tracey, A., Silman, A., Anderson, M., Goodfield, M., McHugh, N. J., Muir, L. & Denton, C. P., 2009, In : Arthritis & Rheumatism. 60, 3, p. 878-882 5 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)