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Research Output

2015

Enhanced Patient Involvement and the Need to Revise the Core Set - Report from the Psoriatic Arthritis Working Group at OMERACT 2014

Tillett, W., Eder, L., Goel, N., De Wit, M., Gladman, D. D., FitzGerald, O., Campbell, W., Helliwell, P. S., Gossec, L., Orbai, A-M., Ogdie, A., Strand, V., McHugh, N. J. & Mease, P. J., 1 May 2015, In : The Journal of Rheumatology.

Research output: Contribution to journalArticle

File
23 Citations (Scopus)
150 Downloads (Pure)

Estimating the diagnostic accuracy of rheumatoid factor in UK primary care: a study using the Clinical Practice Research Datalink

Miller, A., Nightingale, A. L., Sammon, C. J., Mahtani, K. R., Holt, T. A., McHugh, N. J. & Luqmani, R. A., Oct 2015, In : Rheumatology. 54, 10, p. 1882-1889 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
114 Downloads (Pure)

Factors influencing work disability in psoriatic arthritis: first results from a large UK multicentre study

Tillett, W., Shaddick, G., Askari, A., Cooper, A., Creamer, P., Clunie, G., Helliwell, P. S., Kay, L., Korendowych, E., Lane, S., Packham, J., Shaban, R., Williamson, L. & McHugh, N., 1 Jan 2015, In : Rheumatology. 54, 1, p. 157-162

Research output: Contribution to journalArticle

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26 Citations (Scopus)
282 Downloads (Pure)

Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions

Hébert, H. L., Bowes, J., Smith, R. L., Flynn, E., Parslew, R., Alsharqi, A., McHugh, N. J., Barker, J. N. W. N., Griffiths, C. E. M., Barton, A. & Warren, R. B., 1 Apr 2015, In : British Journal of Dermatology. 172, 4, p. 933-939 7 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Increasing incidence of immune-mediated necrotizing myopathy: single-centre experience

Klein, M., Mann, H., Pleštilová, L., Zámečník, J., Betteridge, Z., McHugh, N. & Vencovský, J., 6 Aug 2015, In : Rheumatology. 54, 11, p. 2010-2014 5 p.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
125 Downloads (Pure)

Psoriatic Arthritis Mutilans: Characteristics and Natural Radiographic History

Jadon, D. R., Shaddick, G., Tillett, W., Korendowych, E., Robinson, G., Waldron, N., Cavill, C. & McHugh, N. J., 15 May 2015, In : The Journal of Rheumatology.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
118 Downloads (Pure)

PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus

Bowes, J., Loehr, S., Budu-Aggrey, A., Uebe, S., Bruce, I. N., Feletar, M., Marzo-Ortega, H., Helliwell, P., Ryan, A. W., Kane, D., Korendowych, E., Alenius, G-M., Giardina, E., Packham, J., McManus, R., FitzGerald, O., Brown, M. A., Behrens, F., Burkhardt, H., McHugh, N. & 4 others, Huffmeier, U., Ho, P., Reis, A. & Barton, A., Oct 2015, In : Annals of the Rheumatic Diseases. 74 , 10, p. 1882-1885 4 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
106 Downloads (Pure)

Reactivity in ELISA with DNA-loaded nucleosomes in patients with proliferative lupus nephritis

Dieker, J., Schlumberger, W., McHugh, N., Hamann, P., van der Vlag, J. & Berden, J. H., Nov 2015, In : Molecular Immunology. 68, 1, p. 20-4 5 p.

Research output: Contribution to journalArticle

File
3 Citations (Scopus)
93 Downloads (Pure)

Review of the psoriatic arthritis working group at OMERACT 12: a report from the GRAPPA 2014 annual meeting

Tillett, W., Eder, L., Goel, N., De Wit, M., Ogdie, A., Orbai, A. M., Campbell, W., Fitzgerald, O., McHugh, N. J., Gladman, D. D., Strand, V. & Mease, P. J., 1 Jun 2015, In : Journal of Rheumatology. 42, 6, p. 1048-1051 4 p.

Research output: Contribution to journalArticle

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5 Citations (Scopus)
107 Downloads (Pure)

Serum Soluble Bone Turnover Biomarkers in Psoriatic Arthritis and Psoriatic Spondyloarthropathy

Jadon, D. R., Nightingale, A. L., McHugh, N. J., Lindsay, M. A., Korendowych, E. & Sengupta, R., 1 Jan 2015, In : The Journal of Rheumatology. 42, 1, p. 21-30

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
61 Downloads (Pure)

The evidence for immunotherapy in dermatomyositis and polymyositis: a systematic review

Vermaak, E., Tansley, S. L. & McHugh, N. J., Dec 2015, In : Clinical Rheumatology. 34, 12, p. 2089-2095

Research output: Contribution to journalArticle

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12 Citations (Scopus)
164 Downloads (Pure)

Tumour necrosis factor inhibitor monotherapy vs combination with MTX in the treatment of PsA: a systematic review of the literature

Behrens, F., Cañete, J. D., Olivieri, I., van Kuijk, A. W., McHugh, N. & Combe, B., May 2015, In : Rheumatology. 54, 5, p. 915-926 12 p.

Research output: Contribution to journalArticle

File
37 Citations (Scopus)
120 Downloads (Pure)
Open Access
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29 Citations (Scopus)
149 Downloads (Pure)

Verna Wright Lecture: Psoriatic Arthritis: The Need for Early Intervention

McHugh, N. J., Nov 2015, In : The Journal of rheumatology. Supplement. 93, p. 10-13 4 p.

Research output: Contribution to journalArticle

File
2 Citations (Scopus)
136 Downloads (Pure)
2014

Abnormal cardiac enzymes in systemic sclerosis: A report of four patients and review of the literature

Vasta, B., Flower, V., Bucciarelli-Ducci, C., Brown, S., Korendowych, E., McHugh, N. J. & Pauling, J. D., Mar 2014, In : Clinical Rheumatology. 33, 3, p. 435-438 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study

Tansley, S. L., Betteridge, Z. E., Gunawardena, H., Jacques, T. S., Owens, C. M., Pilkington, C., Arnold, K., Yasin, S., Moraitis, E., Wedderburn, L. R. & McHugh, N. J., 2 Jul 2014, In : Arthritis Research & Therapy. 16, 4, p. 1-8 8 p., R138.

Research output: Contribution to journalArticle

Open Access
75 Citations (Scopus)
39 Downloads (Pure)

Arthritis in Idiopathic Inflammatory Myopathy: Clinical Features and Autoantibody Associations

Klein, M., Mann, H., Pleštilova, L., Betteridge, Z., McHugh, N., Remáková, M., Novota, P. & Vencovsky, J., 1 May 2014, In : The Journal of Rheumatology. 41, 6, p. 1133-1139

Research output: Contribution to journalArticle

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13 Citations (Scopus)
128 Downloads (Pure)

Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset

Tansley, S. L., Betteridge, Z. E., Shaddick, G., Gunawardena, H., Arnold, K., Wedderburn, L. R., McHugh, N. J. & on behalf of the Juvenile Dermatomyositis Research Group, 1 Dec 2014, In : Rheumatology. 53, 12, p. 2204-2208 5 p.

Research output: Contribution to journalArticle

Open Access
63 Citations (Scopus)
35 Downloads (Pure)

Development and testing of new candidate psoriatic arthritis screening questionnaires combining optimal questions from existing tools

Coates, L. C., Walsh, J., Haroon, M., Fitzgerald, O., Aslam, T., Al Balushi, F., Burden, A. D., Burden-Teh, E., Caperon, A. R., Cerio, R., Chattopadhyay, C., Chinoy, H., Goodfield, M. J. D., Kay, L., Kelly, S., Kirkham, B. W., Lovell, C. R., Marzo-Ortega, H., McHugh, N., Murphy, R. & 7 others, Reynolds, N. J., Smith, C. H., Stewart, E. J. C., Warren, R. B., Waxman, R., Wilson, H. E. & Helliwell, P. S., 27 Jan 2014, In : Arthritis Care and Research. 66, 9, p. 1410-1416 27 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
124 Downloads (Pure)

Development of a Disease Activity and Responder Index for Psoriatic Arthritis -- Report of the Psoriatic Arthritis Module at OMERACT 11

Coates, L. C., Fitzgerald, O., Mease, P. J., Gladman, D. D., Strand, V., Goel, N., Campbell, I., Krueger, G., McHugh, N. J. & Helliwell, P. S., 1 Feb 2014, In : The Journal of Rheumatology. 41, 4, p. 782-791 9 p.

Research output: Contribution to journalArticle

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31 Citations (Scopus)
127 Downloads (Pure)

Drug therapies for peripheral joint disease in psoriatic arthritis: a systematic review

Acosta Felquer, M. L., Coates, L. C., Soriano, E. R., Ranza, R., Espinoza, L. R., Helliwell, P. S., FitzGerald, O., McHugh, N., Roussou, E. & Mease, P. J., Nov 2014, In : The Journal of Rheumatology. 41, 11, p. 2277-2285 9 p.

Research output: Contribution to journalArticle

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34 Citations (Scopus)
135 Downloads (Pure)

Feasibility, reliability, and sensitivity to change of four radiographic scoring methods in patients with psoriatic arthritis

Tillett, W., Jadon, D., Shaddick, G., Robinson, G., Sengupta, R., Korendowych, E., de Vries, C. S. & McHugh, N. J., Feb 2014, In : Arthritis Care and Research. 66, 2, p. 311-317 7 p.

Research output: Contribution to journalArticle

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12 Citations (Scopus)
182 Downloads (Pure)
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1 Citation (Scopus)
111 Downloads (Pure)

Low-dose aspirin vs low-dose aspirin plus low-intensity warfarin in thromboprophylaxis: A prospective, multicentre, randomized, open, controlled trial in patients positive for antiphospholipid antibodies (ALIWAPAS)

Cuadrado, M. J., Bertolaccini, M. L., Seed, P. T., Tektonidou, M. G., Aguirre, A., Mico, L., Gordon, C., Ruiz-Irastorza, G., Egurbide, M. V., Gil, A., Espinosa, G., Houssiau, F., Rahman, A., Martin, H., Mchugh, N., Galindo, M., Akil, M., Amigo, M. C., Murru, V. & Khamashta, M. A., 1 Feb 2014, In : Rheumatology. 53, 2, p. 275-284 10 p., ket313.

Research output: Contribution to journalArticle

46 Citations (Scopus)
File
18 Citations (Scopus)
139 Downloads (Pure)

Other seronegative spondyloarthropathies

Jadon, D. R. & McHugh, N. J., 1 May 2014, In : Medicine. 42, 5, p. 257-261 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Patient involvement in outcome measures for psoriatic arthritis

Tillett, W., Adebajo, A., Brooke, M., Campbell, W., Coates, L. C., Fitzgerald, O., Gossec, L., Helliwell, P., Hewlett, S., James, J., Minnock, P., Reast, A., O'Sullivan, D., de Wit, M. & McHugh, N., May 2014, In : Current Rheumatology Reports. 16, 5, p. 1-10 10 p.

Research output: Contribution to journalArticle

File
23 Citations (Scopus)
149 Downloads (Pure)

Patient Participation in Psoriasis and Psoriatic Arthritis Outcome Research: A Report from the GRAPPA 2013 Annual Meeting

de Wit, M., Campbell, W., FitzGerald, O., Gladman, D. D., Helliwell, P. S., James, J., Lindsay, C., MacDonald, R., McHugh, N. J., Mease, P. J., Orbai, A-M., Palominos, P., Parkinson, A., Tillett, W. & Goel, N., Jun 2014, In : The Journal of Rheumatology. 41, 6, p. 1206-11 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2013
41 Citations (Scopus)

A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus

Ferbas, J., Belouski, S. S., Horner, M., Kaliyaperumal, A., Chen, L., Boyce, M., Colaço, C. B., Mchugh, N., Quick, V., Nicholl, R. J., Siu, G. & Chung, J., 1 Aug 2013, In : British Journal Of Clinical Pharmacology. 76, 2, p. 188-202 15 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A surprise behind a case of winter vomiting virus

Panopoulou, A., Vermaak, E. & McHugh, N., 22 Jul 2013, In : BMJ Case Reports. p. 1-4 4 p.

Research output: Contribution to journalArticle

Brief report: Reduced joint counts misclassify patients with oligoarticular psoriatic arthritis and miss significant numbers of patients with active disease

Coates, L. C., Fitzgerald, O., Gladman, D. D., McHugh, N., Mease, P., Strand, V. & Helliwell, P. S., Jun 2013, In : Arthritis and Rheumatism. 65, 6, p. 1504-1509 6 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Comparison of three screening tools to detect psoriatic arthritis in patients with psoriasis (CONTEST study)

Coates, L. C., Aslam, T., Al Balushi, F., Burden, A. D., Burden-The, E., Caperon, A. R., Cerio, R., Chattopadhyay, C., Chinoy, H., Goodfield, M. J. D., Kay, L., Kelly, S., Kirkham, B. W., Lovell, C. R., Marzo-Ortega, H., McHugh, N., Murphy, R., Reynolds, N. J., Smith, C. H., Stewart, E. J. C. & 4 others, Warren, R. B., Waxman, R., Wilson, H. E. & Helliwell, P. S., Apr 2013, In : British Journal of Dermatology. 168, 4, p. 802-807 6 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Exploring ankylosing spondylitis-associated ERAP1, IL23R and IL12B gene polymorphisms in subphenotypes of psoriatic arthritis

Jadon, D., Tillett, W., Wallis, D., Cavill, C., Bowes, J., Waldron, N., Dixon, A., Sengupta, R., Barton, A., Korendowych, E. & McHugh, N. J., Feb 2013, In : Rheumatology. 52, 2, p. 261-6 6 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Health-related utility values of patients with primary Sjögren's syndrome and its predictors

Lendrem, D., Mitchell, S., McMeekin, P., Bowman, S., Price, E., Pease, C. T., Emery, P., Andrews, J., Lanyon, P., Hunter, J., Gupta, M., Bombardieri, M., Sutcliffe, N., Pitzalis, C., McLaren, J., Cooper, A., Regan, M., Giles, I., Isenberg, D., Vadivelu, S. & 9 others, Coady, D., Dasgupta, B., McHugh, N., Young-Min, S., Moots, R., Gendi, N., Akil, M., Griffiths, B. & Ng, W-F., 12 Jun 2013, In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Mortality in systemic sclerosis-a single centre study from the UK

Strickland, G., Pauling, J., Cavill, C., Shaddick, G. & McHugh, N., Oct 2013, In : Clinical Rheumatology. 32, 10, p. 1533-1539 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Polymorphisms in IL-1B distinguish between psoriasis of early and late onset

Hébert, H. L., Bowes, J., Smith, R. L., McHugh, N. J., Barker, J. N. W. N., Griffiths, C. E. M., Barton, A. & Warren, R. B., 2013, In : Journal Of Investigative Dermatology. 134, 5, p. 1459-1462

Research output: Contribution to journalArticle

14 Citations (Scopus)

Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis

Tillett, W., Jadon, D., Shaddick, G., Cavill, C., Korendowych, E., De Vries, C. S. & McHugh, N., Aug 2013, In : Annals of the Rheumatic Diseases. 72, 8, p. 1358-1361 3 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Statin-induced necrotizing myositis - A discrete autoimmune entity within the "statin-induced myopathy spectrum"

Hamann, P. D. H., Cooper, R. G., McHugh, N. J. & Chinoy, H., 1 Oct 2013, In : Autoimmunity Reviews. 12, 12, p. 1177-1181 5 p.

Research output: Contribution to journalArticle

41 Citations (Scopus)

Symptoms and diagnosis of psoriatic arthritis

Jadon, D. & McHugh, N. J., 1 May 2013, Advances in the Management of Psoriatic Arthritis. Future Medicine Ltd., p. 7-22 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics

Coates, L. C., Tillett, W., Chandler, D., Helliwell, P. S., Korendowych, E., Kyle, S., McInnes, I. B., Oliver, S., Ormerod, A., Smith, C., Symmons, D., Waldron, N. & McHugh, N. J., 2013, In : Rheumatology. 52, 10, p. 1754-1757 4 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

The contribution of platelets to the pathogenesis of Raynaud's phenomenon and systemic sclerosis

Pauling, J. D., O'Donnell, V. B. & McHugh, N. J., 2013, In : Platelets. 24, 7, p. 503-515 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

The development of candidate composite disease activity and responder indices for psoriatic arthritis (GRACE project)

Helliwell, P. S., FitzGerald, O., Fransen, J., Gladman, D. D., Kreuger, G. G., Callis-Duffin, K., McHugh, N., Mease, P. J., Strand, V., Waxman, R., Azevedo, V. F., Ostos, A. B., Carneiro, S., Cauli, A., Espinoza, L. R., Flynn, J. A., Hassan, N., Healy, P., Kerzberg, E. M., Lee, Y. J. & 17 others, Lubrano, E., Marchesoni, A., Marzo-Ortega, H., Porru, G., Moreta, E. G., Nash, P., Raffayova, H., Ranza, R., Raychaudhuri, S. P., Roussou, E., Scarpa, R., Song, Y., Soriano, E., Tak, P. P., Ujfalussy, I., de Vlam, K. & Walsh, J. A., Jun 2013, In : Annals of the Rheumatic Diseases. 72, 6, p. 986-991 6 p.

Research output: Contribution to journalArticle

148 Citations (Scopus)

The diagnostic utility of autoantibodies in adult and juvenile myositis

Tansley, S. L., Betteridge, Z. E. & Mchugh, N. J., Nov 2013, In : Current Opinion in Rheumatology. 25, 6, p. 772-777 6 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Variants in RUNX3 contribute to susceptibility to psoriatic arthritis exhibiting further common ground with ankylosing spondylitis

Apel, M., Uebe, S., Bowes, J., Giardina, E., Korendowych, E., Juneblad, K., Pasutto, F., Ekici, A. B., McManus, R., Ho, P., Bruce, I. N., Ryan, A. W., Behrens, F., Böhm, B., Traupe, H., Lohmann, J., Gieger, C., Wichmann, H-E., Padyukov, L., Fitzgerald, O. & 7 others, Alenius, G-M., McHugh, N. J., Novelli, G., Burkhardt, H., Barton, A., Reis, A. & Hüffmeier, U., May 2013, In : Arthritis & Rheumatism. 65, 5, p. 1224-1231

Research output: Contribution to journalArticle

38 Citations (Scopus)
2012

Anti-Golgi autoantibodies: prevalence and disease associations in a rheumatic disease population

Wallis, D., Greig, A., Dunphy, J., Owen, P. & McHugh, N., Apr 2012, In : International journal of rheumatic diseases. 15, 2, p. e23-e25

Research output: Contribution to journalArticle

2 Citations (Scopus)

A randomized placebo-controlled trial of methotrexate in psoriatic arthritis

Kingsley, G. H., Kowalczyk, A., Taylor, H., Ibrahim, F., Packham, J. C., McHugh, N. J., Mulherin, D. M., Kitas, G. D., Chakravarty, K., Tom, B. D. M., O'Keeffe, A. G., Maddison, P. J. & Scott, D. L., Aug 2012, In : Rheumatology. 51, 8, p. 1368-1377 10 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)

Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome

Newton, J. L., Frith, J., Powell, D., Hackett, K., Wilton, K., Bowman, S., Price, E., Pease, C., Andrews, J., Emery, P., Hunter, J., Gupta, M., Vadivelu, S., Giles, I., Isenberg, D., Lanyon, P., Jones, A., Regan, M., Cooper, A., Moots, R. & 97 others, Sutcliffe, N., Bombardieri, M., Pitzalis, C., McLaren, J., Young-Min, S., Dasgupta, B., Griffiths, B., Lendrem, D., Mitchell, S., Ng, W-F., Bacabac, E. C., Moots, R., Chadravarty, K., Lamabadusuriya, S., Bombardieri, M., Pitzalis, C., Sutcliffe, N., Gendi, N., Adeniba, R., Hamburger, J., Richards, A., Rauz, S., Brailsford, S., Logan, J., Mulherin, D., Andrews, J., Emery, P., McManus, A., Pease, C., Booth, A., Regan, M., Dimitroulas, T., Kadiki, L., Kaur, D., Kitas, G., Lloyd, M., Moore, L., Gordon, E., Lawson, C., Gupta, M., Hunter, J., Stirton, L., Ortiz, G., Price, E., Clunie, G., Rose, G., Cuckow, S., Knight, S., Symmons, D., Jones, B., Carr, A., Edgar, S., Carrozzo, M., Figuereido, F., Foggo, H., Gillespie, C., Lendrem, D., Macleod, I., Mitchell, S., Tarn, J., Jones, A., Lanyon, P., Muir, A., White, P., Young-Min, S., Pugmire, S., Vadivelu, S., Cooper, A., Watkins, M., Field, A., Kaye, S., Mewar, D., Medcalf, P., Tomlinson, P., Whiteside, D., McHugh, N., Pauling, J., James, J., Olaitan, N., Akil, M., McDermott, J., Godia, O., Coady, D., Kidd, E., Palmer, L., Dasgupta, B., Katsande, V., Long, P., Chandra, U., MacKay, K., Fedele, S., Ferenkeh-Koroma, A., Isenberg, D., Marconnell, H., Porter, S., Allcoat, P. & McLaren, J., 2012, In : Annals of the Rheumatic Diseases. 71, 12, p. 1973-1979

Research output: Contribution to journalArticle

37 Citations (Scopus)
34 Citations (Scopus)

Current management of dermatomyositis

Vermaak, E. & McHugh, N., 1 Apr 2012, In : International Journal of Clinical Rheumatology. 7, 2, p. 197-215 19 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)