If you made any changes in Pure these will be visible here soon.

Research Output

Article

Abnormal cardiac enzymes in systemic sclerosis: A report of four patients and review of the literature

Vasta, B., Flower, V., Bucciarelli-Ducci, C., Brown, S., Korendowych, E., McHugh, N. J. & Pauling, J. D., Mar 2014, In : Clinical Rheumatology. 33, 3, p. 435-438 4 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
41 Citations (Scopus)

Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting

Abraham, S., Barton, A., Eder, L., Lim, A., McGonagle, D., McHugh, N., Pennington, S., Sengupta, R., Siebert, S., Bowness, P., Schafer, P. H., Cullen, E. & FitzGerald, O., 15 Oct 2018, In : Seminars in Arthritis and Rheumatism. 48, p. 1005-1013 9 p.

Research output: Contribution to journalArticle

Open Access

A highly conserved 72,000 dalton centromeric antigen reactive with autoantibodies from patients with progressive systemic sclerosis

McNeilage, L. J., Whittingham, S., McHugh, N. & Barnett, A. J., 15 Oct 1986, In : The Journal of Immunology. 137, 8, p. 2541-7 7 p.

Research output: Contribution to journalArticle

A modified Sharp score demonstrates disease progression in established psoriatic arthritis

Ravindran, J., Cavill, C., Balakrishnan, C., Jones, S. M., Korendowych, E. & McHugh, N. J., Jan 2010, In : Arthritis Care & Research. 62, 1, p. 86-91 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma

Hoyles, R. K., Ellis, R. W., Wellsbury, J., Lees, B., Newlands, P., Goh, N. S. L., Roberts, C., Desai, S., Herrick, A. L., McHugh, N. J., Foley, N. M., Pearson, S. B., Emery, P., Veale, D. J., Denton, C. P., Wells, A. U., Black, C. M. & du Bois, R. M., Dec 2006, In : Arthritis & Rheumatism. 54, 12, p. 3962-3970 9 p.

Research output: Contribution to journalArticle

466 Citations (Scopus)

A Multicenter Nominal Group Study to Rank Outcomes Important to Patients, and Their Representation in Existing Composite Outcome Measures for Psoriatic Arthritis

Tillett, W., Dures, E., Hewlett, S., Helliwell, P. S., Fitzgerald, O., Brooke, M., James, J., Lord, J., Bowen, C., de Wit, M., Orbai, A-M., McHugh, N. & PROMPT study group, 4 Oct 2017, In : The Journal of Rheumatology. 44, 10, p. 1445-1452

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
116 Downloads (Pure)

A Multicenter Study of the Validity and Reliability of Responses to Hand Cold Challenge as Measured by Laser Speckle Contrast Imaging and Thermography: outcome measures for systemic sclerosis-related Raynaud's phenomenon

Wilkinson, J. D., Leggett, S. A., Marjanovic, E. J., Moore, T. L., Allen, J., Anderson, M. E., Britton, J., Buch, M. H., Galdo, F. D., Denton, C. P., Dinsdale, G., Griffiths, B., Hall, F., Howell, K., MacDonald, A., McHugh, N. J., Manning, J. B., Pauling, J. D., Roberts, C., Shipley, J. A. & 2 others, Herrick, A. L. & Murray, A. K., 1 Jun 2018, In : Arthritis & Rheumatology. 70, 6, p. 903-911 9 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
24 Downloads (Pure)

A multi-national qualitative research study exploring the patient experience of Raynaud's phenomenon in systemic sclerosis

Pauling, J. D., Domsic, R. T., Saketkoo, L. A., Almeida, C., Withey, J., Jay, H., Frech, T. M., Ingegnoli, F., Dures, E., Robson, J., McHugh, N. J., Herrick, A. L., Matucci-Cerinic, M., Khanna, D. & Hewlett, S., 30 Sep 2018, In : Arthritis Care and Research. 70, 9, p. 1373-1384

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
49 Downloads (Pure)

A novel assay to measure B cell responses to keyhole limpet haemocyanin vaccination in healthy volunteers and subjects with systemic lupus erythematosus

Ferbas, J., Belouski, S. S., Horner, M., Kaliyaperumal, A., Chen, L., Boyce, M., Colaço, C. B., Mchugh, N., Quick, V., Nicholl, R. J., Siu, G. & Chung, J., 1 Aug 2013, In : British Journal Of Clinical Pharmacology. 76, 2, p. 188-202 15 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Anticardiolipin and antineutrophil antibodies in giant cell arteritis

McHugh, N. J., James, I. E. & Plant, G. T., 1990, In : Journal of Rheumatology. 17, 7, p. 916-922 7 p.

Research output: Contribution to journalArticle

Anticardiolipin and antinuclear antibodies in cancer patients--a case control study

Armas, J. B., Dantas, J., Mendonça, D., Farto, R., Ribeiro, M., Herrero-Beaumont, G., Gouveia, J. & McHugh, N. J., 2000, In : Clinical and Experimental Rheumatology. 18, 2, p. 227-232 6 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Anticardiolipin antibodies, livedo reticularis, and major cerebrovascular and renal disease in systemic lupus erythematosus

McHugh, N. J., Maymo, J., Skinner, R. P., James, I. & Maddison, P. J., Feb 1988, In : Annals of the Rheumatic Diseases. 47, 2, p. 110-115 6 p.

Research output: Contribution to journalArticle

Anticardiolipin antibodies in ischaemic heart disease

Edwards, T., Thomas, R. D. & McHugh, N. J., 16 Oct 1993, In : Lancet. 342, 8877, p. 989

Research output: Contribution to journalArticle

Anti-centromere antibodies (ACA) in systemic sclerosis patients and their relatives: a serological and HLA study

McHugh, N. J., Whyte, J., Artlett, C., Briggs, D. C., Stephens, C. O., Olsen, N. J., Gusseva, N. G., Maddison, P. J., Black, C. M. & Welsh, K., May 1994, In : Clinical And Experimental Immunology. 96, 2, p. 267-274 8 p.

Research output: Contribution to journalArticle

Anti-eukaryotic initiation factor 2B autoantibodies are associated with interstitial lung disease in patients with systemic sclerosis

Betteridge, Z. E., Woodhead, F., Lu, H., Shaddick, G., Bunn, C. C., Denton, C. P., Abraham, D. J., du Bois, R. M., Lewis, M., Wells, A. U. & McHugh, N. J., 1 Nov 2016, In : Arthritis & Rheumatology. 68, 11, p. 2778-2783 6 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
83 Downloads (Pure)

Anti-Golgi autoantibodies: prevalence and disease associations in a rheumatic disease population

Wallis, D., Greig, A., Dunphy, J., Owen, P. & McHugh, N., Apr 2012, In : International journal of rheumatic diseases. 15, 2, p. e23-e25

Research output: Contribution to journalArticle

2 Citations (Scopus)

Anti-HMGCR Autoantibodies in Juvenile Idiopathic Inflammatory Myopathies Identify a Rare but Clinically Important Subset of Patients

Tansley, S. L., Betteridge, Z. E., Simou, S., Jacques, T. S., Pilkington, C., Wood, M., Warrier, K., Wedderburn, L. R. & McHugh, N. J., 1 Apr 2017, In : The Journal of Rheumatology. 44, 4, p. 488-492 5 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
249 Downloads (Pure)

Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study

Tansley, S. L., Betteridge, Z. E., Gunawardena, H., Jacques, T. S., Owens, C. M., Pilkington, C., Arnold, K., Yasin, S., Moraitis, E., Wedderburn, L. R. & McHugh, N. J., 2 Jul 2014, In : Arthritis Research & Therapy. 16, 4, p. 1-8 8 p., R138.

Research output: Contribution to journalArticle

Open Access
75 Citations (Scopus)
39 Downloads (Pure)

Antineutrophil cytoplasmic antibodies and HLA class II alleles in minocycline-induced lupus-like syndrome

Dunphy, J., Oliver, M., Rands, A. L., Lovell, C. R. & McHugh, N. J., Mar 2000, In : British Journal of Dermatology. 142, 3, p. 461-467 7 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

Antinuclear antibodies and clinical associations in a British cohort with limited cutaneous systemic sclerosis

Gliddon, A. E., Dore, C. J., Dunphy, J., Betteridge, Z., McHugh, N. J. & Maddison, P. J., 2011, In : Journal of Rheumatology. 38, 4, p. 702-705 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Antiphospholipid syndrome with proliferative vasculopathy and bowel infarction

Patel, Y. I., St John, A. & McHugh, N. J., 1 Jan 2000, In : Rheumatology. 39, 1, p. 108-110 3 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
20 Citations (Scopus)

Anti-synthetase syndrome: a new autoantibody to phenylalanyl transfer RNA synthetase (anti-Zo) associated with polymyositis and interstitial pneumonia

Betteridge, Z., Gunawardena, H., North, J., Slinn, J. & McHugh, N. J., 27 Mar 2007, In : Rheumatology. 46, 6, p. 1005-1008 4 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Anti-topoisomerase I antibodies in silica-associated systemic sclerosis. A model for autoimmunity

McHugh, N. J., Whyte, J., Harvey, G. & Haustein, U. F., Aug 1994, In : Arthritis & Rheumatism. 37, 8, p. 1198-1205 8 p.

Research output: Contribution to journalArticle

A polymorphism in the CTGF promoter region associated with systemic sclerosis

Fonseca, C., Lindahl, G. E., Ponticos, M., Sestini, P., Renzoni, E. A., Holmes, A. M., Spagnolo, P., Pantelidis, P., Leoni, P., McHugh, N. J., Stock, C. J., Shi-Wen, X., Denton, C. P., Black, C. M., Welsh, K. I., du Bois, R. M. & Abraham, D. J., 2007, In : The New England Journal of Medicine. 357, 12, p. 1210-1220 11 p.

Research output: Contribution to journalArticle

147 Citations (Scopus)

A polymorphism in the promoter region of the CD86 (B7.2) gene is associated with systemic sclerosis

Abdallah, A. M., Renzoni, E. A., Anevlavis, S., Lagan, A. L., Munkonge, F. M., Fonseca, C., Black, C. M., Briggs, D., Wells, A. U., Marshall, S. E., McHugh, N., du Bois, R. M. & Welsh, K. I., Jun 2006, In : International journal of immunogenetics. 33, 3, p. 155-161 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Apoptosis-new clues to the pathogenesis of Sjögren's syndrome?

Patel, Y. I. & McHugh, N. J., Feb 2000, In : Rheumatology. 39, 2, p. 119-121 3 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A prospective study of pregnancy outcome in women screened at a routine antenatal clinic for anticardiolipin antibodies

Stuart, R. A., Kornman, L. H. & McHugh, N. J., Jul 1993, In : British Journal of Obstetrics and Gynaecology. 100, 6, p. 599-600 2 p.

Research output: Contribution to journalArticle

A qualitative investigation into the impact of group education upon participants’ management of their disease in lupus and scleroderma

Brown, SJ., Somerset, ME., McCabe, CS. & McHugh, N. J., 2004, In : Musculoskeletal Care. 2, 4, p. 207-217 11 p.

Research output: Contribution to journalArticle

A randomized placebo-controlled trial of methotrexate in psoriatic arthritis

Kingsley, G. H., Kowalczyk, A., Taylor, H., Ibrahim, F., Packham, J. C., McHugh, N. J., Mulherin, D. M., Kitas, G. D., Chakravarty, K., Tom, B. D. M., O'Keeffe, A. G., Maddison, P. J. & Scott, D. L., Aug 2012, In : Rheumatology. 51, 8, p. 1368-1377 10 p.

Research output: Contribution to journalArticle

194 Citations (Scopus)

A rare coding allele in IFIH1 is protective for psoriatic arthritis

Budu-Aggrey, A., Bowes, J., Stuart, P. E., Zawistowski, M., Tsoi, L. C., Nair, R., Jadon, D. R., McHugh, N., Korendowych, E., Elder, J. T., Barton, A. & Raychaudhuri, S., 1 Jul 2017, In : Annals of the Rheumatic Diseases. 76, 7, p. 1321-1324

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
57 Downloads (Pure)

Arthritis in Idiopathic Inflammatory Myopathy: Clinical Features and Autoantibody Associations

Klein, M., Mann, H., Pleštilova, L., Betteridge, Z., McHugh, N., Remáková, M., Novota, P. & Vencovsky, J., 1 May 2014, In : The Journal of Rheumatology. 41, 6, p. 1133-1139

Research output: Contribution to journalArticle

File
13 Citations (Scopus)
128 Downloads (Pure)

Arthropathy of hands and feet in systemic lupus erythematosus

Reilly, P. A., Evison, G., McHugh, N. J. & Maddison, P. J., Jun 1990, In : Journal of Rheumatology. 17, 6, p. 777-784 8 p.

Research output: Contribution to journalArticle

Association of markers for TGFβ3, TGFβ2 and TIMP1 with systemic sclerosis

Susol, E., Rands, A. L., Herrick, A., McHugh, N., Barrett, J. H., Ollier, W. E. R. & Worthington, J., 2000, In : Rheumatology. 39, 12, p. 1332-1336 5 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis

Smith, R. L., Hébert, H. L., Massey, J., Bowes, J., Marzo-Ortega, H., Ho, P., McHugh, N. J., Worthington, J., Barton, A., Griffiths, C. E. M. & Warren, R. B., Apr 2016, In : Archives of Dermatological Research. 308, 3, p. 201-205

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
111 Downloads (Pure)

Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC Class II alleles in systemic lupus erythematosus.

Chan, M. T., Owen, P., Dunphy, J., Cox, B., Carmichael, C., Korendowych, E. & McHugh, N. J., 2008, In : Journal of Rheumatology. 35, 1, p. 77-83 7 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

A surprise behind a case of winter vomiting virus

Panopoulou, A., Vermaak, E. & McHugh, N., 22 Jul 2013, In : BMJ Case Reports. p. 1-4 4 p.

Research output: Contribution to journalArticle

A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome

James, K., Al-Ali, S., Tarn, J., Cockell, S. J., Gillespie, C. S., Hindmarsh, V., Locke, J., Mitchell, S., Lendrem, D., Bowman, S., Price, E., Pease, C. T., Emery, P., Lanyon, P., Hunter, J. A., Gupta, M., Bombardieri, M., Sutcliffe, N., Pitzalis, C., McLaren, J. & 20 others, Cooper, A., Regan, M., Giles, I., Isenberg, D., Saravanan, V., Coady, D., Dasgupta, B., McHugh, N., Young-Min, S., Moots, R., Gendi, N., Akil, M., Griffiths, B., Wipat, A., Newton, J., Jones, D. E., Isaacs, J., Hallinan, J., Ng, W-F. & UK Primary Sjögren’s Syndrome registry, 2015, In : PLoS ONE. 10, 12, p. e0143970

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
117 Downloads (Pure)

Atypical antineutrophil cytoplasmic antibodies in patients with ankylosing spondylitis

Koh, W. H., Dunphy, J., Dixey, J., Calin, A., McHugh, N. J. & Maddison, P. J., 7 Jul 1995, In : British Journal of Rheumatology. 34, 7, p. 695-696 2 p.

Research output: Contribution to journalArticle

Atypical Behçet's disease with peripheral erosive arthropathy and pyoderma gangrenosum

Armas, J. B., Davies, J., Davis, M., Lovell, C. & McHugh, N., 1992, In : Clinical and Experimental Rheumatology. 10, 2, p. 177-180 4 p.

Research output: Contribution to journalArticle

Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort

on behalf of the Juvenile Dermatomyositis Research Group, 1 Nov 2017, In : Journal of Autoimmunity. 84, p. 55-64 10 p.

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)

Autoantibodies to a 140-kd protein in juvenile dermatomyositis are associated with calcinosis

Gunawardena, H., Wedderburn, L. R., Chinoy, H., Betteridge, Z. E., North, J., Ollier, W. E. R., Cooper, R. G., Oddis, C. V., Ramanan, A. V., Davidson, J. E. & McHugh, N. J., Jun 2009, In : Arthritis & Rheumatism. 60, 6, p. 1807-1814 8 p.

Research output: Contribution to journalArticle

152 Citations (Scopus)

Autoantibodies to mitochondrial and centromere antigens in primary biliary cirrhosis and systemic sclerosis

McHugh, N. J., James, I. E., Fairburn, K. & Maddison, P. J., 1990, In : Clinical And Experimental Immunology. 81, 2, p. 244-9 6 p.

Research output: Contribution to journalArticle

Autoantibody specificities and type I interferon pathway activation in Idiopathic Inflammatory Myopathies

Ekholm, L., Vosslamber, S., Tjarnlund, A., de Jong, T., Betteridge, Z., McHugh, N., Pleštilová, L., Klein, M., Padyukov, L., Voskuyl, AE., Bultink, IE., Pegtel, DM., Mavragani, CP., Crow, MK., Vencovsky, J., Lundberg, I. & Verweij, CL., Aug 2016, In : Scandinavian Journal of Immunology . 84, 2, p. 100-109

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
124 Downloads (Pure)

Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome

Newton, J. L., Frith, J., Powell, D., Hackett, K., Wilton, K., Bowman, S., Price, E., Pease, C., Andrews, J., Emery, P., Hunter, J., Gupta, M., Vadivelu, S., Giles, I., Isenberg, D., Lanyon, P., Jones, A., Regan, M., Cooper, A., Moots, R. & 97 others, Sutcliffe, N., Bombardieri, M., Pitzalis, C., McLaren, J., Young-Min, S., Dasgupta, B., Griffiths, B., Lendrem, D., Mitchell, S., Ng, W-F., Bacabac, E. C., Moots, R., Chadravarty, K., Lamabadusuriya, S., Bombardieri, M., Pitzalis, C., Sutcliffe, N., Gendi, N., Adeniba, R., Hamburger, J., Richards, A., Rauz, S., Brailsford, S., Logan, J., Mulherin, D., Andrews, J., Emery, P., McManus, A., Pease, C., Booth, A., Regan, M., Dimitroulas, T., Kadiki, L., Kaur, D., Kitas, G., Lloyd, M., Moore, L., Gordon, E., Lawson, C., Gupta, M., Hunter, J., Stirton, L., Ortiz, G., Price, E., Clunie, G., Rose, G., Cuckow, S., Knight, S., Symmons, D., Jones, B., Carr, A., Edgar, S., Carrozzo, M., Figuereido, F., Foggo, H., Gillespie, C., Lendrem, D., Macleod, I., Mitchell, S., Tarn, J., Jones, A., Lanyon, P., Muir, A., White, P., Young-Min, S., Pugmire, S., Vadivelu, S., Cooper, A., Watkins, M., Field, A., Kaye, S., Mewar, D., Medcalf, P., Tomlinson, P., Whiteside, D., McHugh, N., Pauling, J., James, J., Olaitan, N., Akil, M., McDermott, J., Godia, O., Coady, D., Kidd, E., Palmer, L., Dasgupta, B., Katsande, V., Long, P., Chandra, U., MacKay, K., Fedele, S., Ferenkeh-Koroma, A., Isenberg, D., Marconnell, H., Porter, S., Allcoat, P. & McLaren, J., 2012, In : Annals of the Rheumatic Diseases. 71, 12, p. 1973-1979

Research output: Contribution to journalArticle

37 Citations (Scopus)

Axial Disease in Psoriatic Arthritis study: defining the clinical and radiographic phenotype of psoriatic spondyloarthritis

Jadon, D. R., Sengupta, R., Nightingale, A., Lindsay, M., Korendowych, E., Robinson, G., Jobling, A., Shaddick, G., Bi, J., Winchester, R., Giles, J. T. & McHugh, N. J., 10 Mar 2017, In : Annals of the Rheumatic Diseases. 76, 4, p. 701-707 7 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
127 Downloads (Pure)

B-cell activity markers are associated with different disease activity domains in primary Sjögren's syndrome

for the UK Primary Sjögren's Syndrome Registry, 1 Jul 2018, In : Rheumatology (United Kingdom). 57, 7, p. 1222-1227 6 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

BILAG 2004. Development and initial validation of an updated version of the British Isles Lupus Assessment Group's disease activity index for patients with systemic lupus erythematosus

Isenberg, D. A., Rahman, A., Allen, E., Farewell, V., Akil, M., Bruce, I. N., D'Cruz, D., Griffiths, B., Khamashta, M., Maddison, P., McHugh, N., Snaith, M., Teh, L. S., Yee, C. S., Zoma, A. & Gordon, C., 2005, In : Rheumatology. 44, 7, p. 902-906 5 p.

Research output: Contribution to journalArticle

293 Citations (Scopus)

BILAG-2004 index captures systemic lupus erythematosus disease activity better than SLEDAI-2000

Yee, C. S., Isenberg, D. A., Prabu, A., Sokoll, K., Teh, L. S., Rahman, A., Bruce, I. N., Griffiths, B., Akil, M., McHugh, N. J., D'Cruz, D., Khamashta, M. A., Maddison, P., Zoma, A. & Gordon, C., 2008, In : Annals of the Rheumatic Diseases. 67, 6, p. 873-876 4 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)