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Personal profile

Research interests

Professor Neil McHugh graduated from Otago University Medical School, Dunedin, New Zealand, and completed physician training before specialising in the subspecialty of rheumatology. He has undertaken research fellowships at the Walter and Eliza Hall in Melbourne, Australia (1985), Yale University Medical School, USA (1990–1991), and the National Heart and Lung Institute, UK (2002–2004).

Professor McHugh has been a Consultant Rheumatologist at the RNHRD since 1991, and Professor of Pharmacoepidemiology at the University of Bath since 2013. His current interests include the serology of idiopathic inflammatory myositis, scleroderma, lupus and juvenile idiopathic arthritis. His laboratory group offers specialist autoimmune serology at the University of Bath, leads on a major European study of adult and juvenile idiopathic myositis, and has identified a number of novel diagnostic autoantibody biomarkers. Professor McHugh also leads a programme of work related to psoriatic disease, including a National Institute for Health Research programme grant related to the early detection and optimisation of outcome measures in psoriatic arthritis. He has led on successive British Society for Rheumatology guidelines for biologics in psoriatic arthritis, and has been involved in National Institute for Health and Care Excellence and other international guidelines for psoriatic disease.

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Projects 2007 2021

Biomarkers in Interstitial Lung Disease

McHugh, N.

3/09/182/09/19

Project: Central government, health and local authorities

Development of Myositis ELISA

McHugh, N.

1/08/1831/01/20

Project: UK charity

Novel Biomarkers in Idiopathic Inflammatory Myositis

McHugh, N. & Tansley, S.

19/04/1818/04/19

Project: UK charity

Validation of myositis autoantibody tests (Cure JM)

McHugh, N. & Tansley, S.

1/01/1830/05/19

Project: Other

Biomarkers in ankylosing spondylitis

McHugh, N., Betteridge, Z. & Green, A.

5/10/175/01/21

Project: UK industry

Research Output 1978 2018

7 Citations

Autoantibodies in myositis

McHugh, N. J. & Tansley, S. L., 1 May 2018, In : Nature reviews. Rheumatology. 14, 5, p. 290-302 13 p.

Research output: Contribution to journalReview article

Open Access
Myositis
Autoantibodies
Autoantigens
Inborn Genetic Diseases
Disease Management

Validation of the Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire and its potential as a single-item outcome measure in clinical practice

Holland, R., Tillett, W., Korendowych, E., Cavill, C., Waldron, N., Brooke, M. & McHugh, N. J., 15 Nov 2017, In : Annals of the Rheumatic Diseases. p. 1 - 5 5 p.

Research output: Contribution to journalArticle

Open Access
File
Psoriatic Arthritis
Outcome Assessment (Health Care)
PROM
Surveys and Questionnaires
10 Citations

Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort

Tansley, S. L., Simou, S., Shaddick, G., Betteridge, Z. E., Almeida, B., Gunawardena, H., Thomson, W., Beresford, M. W., Midgley, A., Muntoni, F., Wedderburn, L. R. & McHugh, N. J., Nov 2017, In : Journal of Autoimmunity. 84, p. 55-64

Research output: Contribution to journalArticle

Open Access
Autoantibodies
Myositis
Phenotype
Juvenile dermatomyositis
Juvenile Arthritis
4 Citations
Open Access
File

Thesis

A clinical and serological study of adult and juvenile idiopathic inflammatory myopathy

Author: Gunawardena, H., 1 Sep 2010

Supervisor: Stevens, C. (Supervisor) & McHugh, N. (Supervisor)

Student thesis: Doctoral ThesisPhD

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An investigation into the predictors and frequency of sustained remission in patients with rheumatoid arthritis undergoing treatment with anti-tumour necrosis factor therapy using the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

Author: Hamann, P., 4 Feb 2018

Supervisor: McHugh, N. (Supervisor), Pauling, J. D. (Supervisor), Shaddick, G. (External person) (Supervisor) & Hyrich, K. (External person) (Supervisor)

Student thesis: Doctoral ThesisPhD

Biomarkers of Psoriatic Arthritis Phenotypes

Author: Jadon, D., 26 Jan 2016

Supervisor: McHugh, N. (Supervisor), Nightingale, A. (Supervisor), Sengupta, R. (External person) (Supervisor) & Lindsay, M. (Supervisor)

Student thesis: Doctoral ThesisPhD

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Serological Biomarkers in Systemic Lupus Erythematosus

Author: Chan, M., 18 Sep 2013

Supervisor: McHugh, N. (Supervisor) & Thompson, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Medicine

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