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Personal profile

Research interests

Professor Neil McHugh graduated from Otago University Medical School, Dunedin, New Zealand, and completed physician training before specialising in the subspecialty of rheumatology. He has undertaken research fellowships at the Walter and Eliza Hall in Melbourne, Australia (1985), Yale University Medical School, USA (1990–1991), and the National Heart and Lung Institute, UK (2002–2004).

Professor McHugh has been a Consultant Rheumatologist at the RNHRD since 1991, and Professor of Pharmacoepidemiology at the University of Bath since 2013. His current interests include the serology of idiopathic inflammatory myositis, scleroderma, lupus and juvenile idiopathic arthritis. His laboratory group offers specialist autoimmune serology at the University of Bath, leads on a major European study of adult and juvenile idiopathic myositis, and has identified a number of novel diagnostic autoantibody biomarkers. Professor McHugh also leads a programme of work related to psoriatic disease, including a National Institute for Health Research programme grant related to the early detection and optimisation of outcome measures in psoriatic arthritis. He has led on successive British Society for Rheumatology guidelines for biologics in psoriatic arthritis, and has been involved in National Institute for Health and Care Excellence and other international guidelines for psoriatic disease.

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Projects

Research Output

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge, Z., Tansley, S., Shaddick, G., Chinoy, H., Cooper, R. G., New, R. P., Lilleker, J. B., Vencovsky, J., Chazarain, L., Danko, K., Nagy-Vincze, M., Bodoki, L., Dastmalchi, M., Ekholm, L., Lundberg, I. E. & McHugh, N., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Autoantibodies in myositis

McHugh, N. J. & Tansley, S. L., 1 May 2018, In : Nature reviews. Rheumatology. 14, 5, p. 290-302 13 p.

Research output: Contribution to journalReview article

Open Access
  • 36 Citations (Scopus)
    Open Access
    File
    9 Citations (Scopus)
    47 Downloads (Pure)

    Autoantibodies in juvenile-onset myositis: Their diagnostic value and associated clinical phenotype in a large UK cohort

    on behalf of the Juvenile Dermatomyositis Research Group, 1 Nov 2017, In : Journal of Autoimmunity. 84, p. 55-64 10 p.

    Research output: Contribution to journalArticle

    Open Access
  • 30 Citations (Scopus)

    Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

    Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, p. 1-5 5 p., 848.

    Research output: Contribution to journalArticle

    Open Access
    5 Citations (Scopus)

    Thesis

    A clinical and serological study of adult and juvenile idiopathic inflammatory myopathy

    Author: Gunawardena, H., 1 Sep 2010

    Supervisor: Stevens, C. (Supervisor) & McHugh, N. (Supervisor)

    Student thesis: Doctoral ThesisPhD

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    An investigation into the predictors and frequency of sustained remission in patients with rheumatoid arthritis undergoing treatment with anti-tumour necrosis factor therapy using the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

    Author: Hamann, P., 4 Feb 2018

    Supervisor: McHugh, N. (Supervisor), Pauling, J. D. (Supervisor), Shaddick, G. (External person) (Supervisor) & Hyrich, K. (External person) (Supervisor)

    Student thesis: Doctoral ThesisPhD

    Biomarkers of Psoriatic Arthritis Phenotypes

    Author: Jadon, D., 26 Jan 2016

    Supervisor: McHugh, N. (Supervisor), Nightingale, A. (Supervisor), Sengupta, R. (External person) (Supervisor) & Lindsay, M. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File
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    Serological Biomarkers in Systemic Lupus Erythematosus

    Author: Chan, M., 18 Sep 2013

    Supervisor: McHugh, N. (Supervisor) & Thompson, D. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Medicine

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