Projects per year
Personal profile
Research interests
I am a molecular fungal biologist and BBSRC Future Leader Fellow / Lecturer at the University of Bath. I am motivated to discover new ways to fight major fungal diseases that threaten our food security and health. I focus on the cereal pathogen Fusarium graminearum and the food spoilage mould Aspergillus nidulans, which produce harmful toxins that can contaminate our food. A fungal pathogen landing on a plant must decide if it is suitable, where to infect, and when to deploy different virulence strategies. The goal of this research is to discover how fungal pathogens sense the ‘touch and taste’ of their host environment. This research has the applied objective to determine if a pathogen’s sense of ‘touch and taste’ can then be targeted through the development of novel antifungals to prevent disease and toxin contamination.
Education/Academic qualification
Plant Pathogenesis and Crop Protection, Doctor of Philosophy, University of Edinburgh
Award Date: 22 Dec 2011
Plant Molecular Biology and Biotechnology, Master of Research, Imperial College London
Award Date: 1 Sep 2007
Applied Biology, Bachelor of Science, University of Bath
Award Date: 1 Jul 2005
External positions
BBSRC Future Leader Fellow, Rothamsted Research
1 Apr 2016 → …Post-doctoral Researcher, Rothamsted Research
5 Jan 2015 → 31 Mar 2016CNPq Young Talent Fellow, University of Sao Paulo
1 Apr 2013 → 31 Dec 2014FAPESP postdoctoral fellow, University of Sao Paulo
2 Jan 2012 → 30 Mar 2013Keywords
- Fungal Pathogenesis
- Crop Protection
- Mycotoxins
- Sensing
- Fusarium
- Aspergillus
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
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Dynamic membrane environments: regulators of receptor functions & fungal sex?
1/10/20 → 30/09/21
Project: Research council
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GW4 crucible seed funding
Mitchelmore, P., Brown, N., Tyrrell, J., Pritchard, M. & Weiser, R.
1/09/20 → 30/06/21
Project: Research-related funding
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Bath Alumni Fund (F1920B) - Enhancing Infection Biology Research & Teaching.
4/05/20 → …
Project: Research-related funding
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FAPESP - Bath Scheme 2018
Brown, N. & Goldmanm, G. H.
1/04/19 → 1/04/21
Project: Research-related funding
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GCRF - New Tools to Uncover Novel Regulators of Fungal Sex, Disease & Toxin Contamination
1/12/18 → 31/07/19
Project: Other
Research Output
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The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance
Mattos, E. C., Silva, L. P., Valero, C., de Castro, P. A., Dos Reis, T. F., Ribeiro, L. F. C., Marten, M. R., Silva-Rocha, R., Westmann, C., da Silva, C. H. T. D. P., Taft, C. A., Al-Furaiji, N., Bromley, M., Mortensen, U. H., Benz, J. P., Brown, N. A. & Goldman, G. H., 1 Jan 2020, In : mBio. 11, 1, e02962-19.Research output: Contribution to journal › Article
Open Access3 Citations (Scopus) -
Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance
de Castro, P. A., Colabardini, A. C., Manfiolli, A. O., Chiaratto, J., Silva, L. P., Mattos, E. C., Palmisano, G., Almeida, F., Persinoti, G. F., Ries, L. N. A., Mellado, L., Rocha, M. C., Bromley, M., Silva, R. N., de Souza, G. S., Loures, F. V., Malavazi, I., Brown, N. A. & Goldman, G. H., 30 Dec 2019, In : Plos Genetics. 15, 12, e1008551.Research output: Contribution to journal › Article
Open Access5 Citations (Scopus) -
Aspergillus fumigatushigh osmolarity glycerol mitogen activated protein kinases saka and mpkc physically interact during osmotic and cell wall stresses
Manfiolli, A. O., Mattos, E. C., De Assis, L. J., Silva, L. P., Ulas, M., Brown, N. A., Silva-Rocha, R., Bayram, Ö. & Goldman, G. H., 7 May 2019, In : Frontiers in Microbiology. 10, p. 1-17 17 p., 918.Research output: Contribution to journal › Article
Open Access4 Citations (Scopus) -
GPCR-mediated glucose sensing system regulates light-dependent fungal development and mycotoxin production
dos Reis, T. F., Mellado, L., Lohmar, J. M., Silva, L. P., Zhou, J. J., Calvo, A. M., Goldman, G. H. & Brown, N. A., 14 Oct 2019, In : Plos Genetics. 15, 10, p. 1-27 27 p., e1008419.Research output: Contribution to journal › Article
Open Access3 Citations (Scopus) -
Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat
Dilks, T., Halsey, K., De Vos, R. P., Hammond-Kosack, K. E. & Brown, N. A., 30 Apr 2019, In : PLoS Pathogens. 15, 4, p. 1-26 26 p., e1007666.Research output: Contribution to journal › Article
Open Access11 Citations (Scopus)