• 4 SOUTH 1.53

Accepting PhD Students

20052019
If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

I am a molecular fungal biologist and BBSRC Future Leader Fellow / Lecturer at the University of Bath. I am motivated to discover new ways to fight major fungal diseases that threaten our food security and health. I focus on the cereal pathogen Fusarium graminearum and the food spoilage mould Aspergillus nidulans, which produce harmful toxins that can contaminate our food. A fungal pathogen landing on a plant must decide if it is suitable, where to infect, and when to deploy different virulence strategies. The goal of this research is to discover how fungal pathogens sense the ‘touch and taste’ of their host environment. This research has the applied objective to determine if a pathogen’s sense of ‘touch and taste’ can then be targeted through the development of novel antifungals to prevent disease and toxin contamination.

Education/Academic qualification

Plant Pathogenesis and Crop Protection, Doctor of Philosophy, University of Edinburgh

Plant Molecular Biology and Biotechnology, Master of Research, Imperial College London

Applied Biology, Bachelor of Science, University of Bath

External positions

BBSRC Future Leader Fellow, Rothamsted Research

1 Apr 2016 → …

Post-doctoral Researcher, Rothamsted Research

5 Jan 201531 Mar 2016

CNPq Young Talent Fellow, University of Sao Paulo

1 Apr 201331 Dec 2014

FAPESP postdoctoral fellow, University of Sao Paulo

2 Jan 201230 Mar 2013

Keywords

  • Fungal Pathogenesis
  • Crop Protection
  • Mycotoxins
  • Sensing
  • Fusarium
  • Aspergillus

Fingerprint Dive into the research topics where Neil Brown is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Aspergillus fumigatus Medicine & Life Sciences
Aspergillus nidulans Medicine & Life Sciences
Virulence Medicine & Life Sciences
Fungi Medicine & Life Sciences
Cell Wall Medicine & Life Sciences
Aspergillus Chemical Compounds
Fusarium Medicine & Life Sciences
Fusarium graminearum Agriculture & Biology

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2018 2019

Research Output 2005 2019

1 Citation (Scopus)

Aspergillus fumigatushigh osmolarity glycerol mitogen activated protein kinases saka and mpkc physically interact during osmotic and cell wall stresses

Manfiolli, A. O., Mattos, E. C., De Assis, L. J., Silva, L. P., Ulas, M., Brown, N. A., Silva-Rocha, R., Bayram, Ö. & Goldman, G. H., 7 May 2019, In : Frontiers in Microbiology. 10, p. 1-17 17 p., 918.

Research output: Contribution to journalArticle

Open Access

Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat

Dilks, T., Halsey, K., De Vos, R. P., Hammond-Kosack, K. E. & Brown, N. A., 1 Apr 2019, In : PLoS Pathogens. 15, 4, p. 1-26 26 p., e1007666.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)
94 Downloads (Pure)

Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

Brown, N., Schrevens, S., van Dijck, P. & Goldman, G., 1 Apr 2018, In : Nature Microbiology. 3, p. 402–414 13 p.

Research output: Contribution to journalReview article

Open Access
File
Fungal Proteins
G-Protein-Coupled Receptors
GTP-Binding Proteins
Virulence
Fungi
2 Citations (Scopus)

Inter-genome comparison of the Quorn fungus Fusarium venenatum and the closely related plant infecting pathogen Fusarium graminearum

King, R., Brown, N., Urban, M. & Hammond-Kosack, K., 19 Apr 2018, In : BMC Genomics. 19, 1, p. 1-19 19 p., 269.

Research output: Contribution to journalArticle

Open Access
Fusarium
Fungi
Genome
Genes
Chromosomes
11 Citations (Scopus)

RNAi as an emerging approach to control Fusarium head blight disease and mycotoxin contamination in cereals

Machado, A. K., Brown, N. A., Urban, M., Kanyuka, K. & Hammond-Kosack, K. E., 1 Apr 2018, In : Pest Management Science. 74, 4, p. 790-799 10 p.

Research output: Contribution to journalReview article

Open Access
Fusarium head blight
gene silencing
RNA interference
mycotoxins
Fusarium graminearum