• 4 SOUTH 1.53

Accepting PhD Students

20052020

Research output per year

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Personal profile

Research interests

I am a molecular fungal biologist and BBSRC Future Leader Fellow / Lecturer at the University of Bath. I am motivated to discover new ways to fight major fungal diseases that threaten our food security and health. I focus on the cereal pathogen Fusarium graminearum and the food spoilage mould Aspergillus nidulans, which produce harmful toxins that can contaminate our food. A fungal pathogen landing on a plant must decide if it is suitable, where to infect, and when to deploy different virulence strategies. The goal of this research is to discover how fungal pathogens sense the ‘touch and taste’ of their host environment. This research has the applied objective to determine if a pathogen’s sense of ‘touch and taste’ can then be targeted through the development of novel antifungals to prevent disease and toxin contamination.

Education/Academic qualification

Plant Pathogenesis and Crop Protection, Doctor of Philosophy, University of Edinburgh

Plant Molecular Biology and Biotechnology, Master of Research, Imperial College London

Applied Biology, Bachelor of Science, University of Bath

External positions

BBSRC Future Leader Fellow, Rothamsted Research

1 Apr 2016 → …

Post-doctoral Researcher, Rothamsted Research

5 Jan 201531 Mar 2016

CNPq Young Talent Fellow, University of Sao Paulo

1 Apr 201331 Dec 2014

FAPESP postdoctoral fellow, University of Sao Paulo

2 Jan 201230 Mar 2013

Keywords

  • Fungal Pathogenesis
  • Crop Protection
  • Mycotoxins
  • Sensing
  • Fusarium
  • Aspergillus

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Projects

Research Output

The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

Mattos, E. C., Silva, L. P., Valero, C., de Castro, P. A., Dos Reis, T. F., Ribeiro, L. F. C., Marten, M. R., Silva-Rocha, R., Westmann, C., da Silva, C. H. T. D. P., Taft, C. A., Al-Furaiji, N., Bromley, M., Mortensen, U. H., Benz, J. P., Brown, N. A. & Goldman, G. H., 1 Jan 2020, In : mBio. 11, 1, e02962-19.

Research output: Contribution to journalArticle

Open Access

Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance

de Castro, P. A., Colabardini, A. C., Manfiolli, A. O., Chiaratto, J., Silva, L. P., Mattos, E. C., Palmisano, G., Almeida, F., Persinoti, G. F., Ries, L. N. A., Mellado, L., Rocha, M. C., Bromley, M., Silva, R. N., de Souza, G. S., Loures, F. V., Malavazi, I., Brown, N. A. & Goldman, G. H., 30 Dec 2019, In : Plos Genetics. 15, 12, e1008551.

Research output: Contribution to journalArticle

Open Access

Aspergillus fumigatushigh osmolarity glycerol mitogen activated protein kinases saka and mpkc physically interact during osmotic and cell wall stresses

Manfiolli, A. O., Mattos, E. C., De Assis, L. J., Silva, L. P., Ulas, M., Brown, N. A., Silva-Rocha, R., Bayram, Ö. & Goldman, G. H., 7 May 2019, In : Frontiers in Microbiology. 10, p. 1-17 17 p., 918.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

GPCR-mediated glucose sensing system regulates light-dependent fungal development and mycotoxin production

dos Reis, T. F., Mellado, L., Lohmar, J. M., Silva, L. P., Zhou, J. J., Calvo, A. M., Goldman, G. H. & Brown, N. A., 14 Oct 2019, In : Plos Genetics. 15, 10, p. 1-27 27 p., e1008419.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat

Dilks, T., Halsey, K., De Vos, R. P., Hammond-Kosack, K. E. & Brown, N. A., 30 Apr 2019, In : PLoS Pathogens. 15, 4, p. 1-26 26 p., e1007666.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)