Michael Danson

Prof

19972019

Research output per year

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Research Output

2019

Inhibition of extracellular proteases improves the production of a xylanase in Parageobacillus thermoglucosidasius

Holland, A. T. N., Danson, M. J. & Bolhuis, A., 20 Mar 2019, In : BMC Biotechnology. 19, 1, 17.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2018

Crystal structure of an inferred ancestral bacterial pyruvate decarboxylase

Buddrus, L., Andrews, E. S. V., Leak, D., Danson, M., Arcus, V. L. & Crennell, S., 1 Mar 2018, In : Acta Crystallographica Section F:Structural Biology Communications. 74, 3, p. 179-186 8 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
File
1 Citation (Scopus)
29 Downloads (Pure)

Uncovering the relationship between the change in heat capacity for enzyme catalysis and vibrational frequency through isotope effect studies

Jones, H. B. L., Crean, R. M., Matthews, C., Troya, A. B., Danson, M. J., Bull, S. D., Arcus, V. L., Van Der Kamp, M. W. & Pudney, C. R., 1 Jun 2018, In : ACS Catalysis. 8, 6, p. 5340-5349 10 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
57 Downloads (Pure)
2017

Development of an efficient technique for gene deletion and allelic exchange in Geobacillus spp.

Bacon, L. F., Hamley-Bennett, C., Danson, M. J. & Leak, D. J., 5 Apr 2017, In : Microbial Cell Factories. 16, 1, 8 p., 58.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2016

Crystal structure of pyruvate decarboxylase from Zymobacter palmae

Buddrus, L., Andrews, E. S. V., Leak, D. J., Danson, M. J., Arcus, V. L. & Crennell, S. J., 1 Sep 2016, In : Acta Crystallographica Section F:Structural Biology Communications. 72, 9, p. 700-706

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
98 Downloads (Pure)

Investigating bottlenecks during protein secretion in Geobacillus thermoglucosidasisius

Holland, A., Danson, M. & Bolhuis, A., Nov 2016.

Research output: Contribution to conferencePoster

Structure of an acetylating aldehyde dehydrogenase from the thermophilic ethanologen Geobacillus thermoglucosidasius

Extance, J., Danson, M. J. & Crennell, S. J., 29 Aug 2016, In : Protein Science. 25, 11, p. 2045-2053

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
144 Downloads (Pure)
2014
Open Access
File
10 Citations (Scopus)
902 Downloads (Pure)

Comparative genomic analysis reveals 2-oxoacid dehydrogenase complex lipoylation correlation with aerobiosis in archaea

Borziak, K., Posner, M., Upadhyay, A., Danson, M., Bagby, S. & Dorus, S., 28 Jan 2014, In : PLoS ONE. 9, p. 1 - 9 9 p., e87063.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
200 Downloads (Pure)

Draft genome sequences of Geobacillus sp. strains CAMR5420 and CAMR12739

De Maayer, P., Williamson, C. E., Vennard, C. T., Danson, M. J. & Cowan, D. A., 2014, In : Genome announcements. 2, 3, e00567-14.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
File
20 Citations (Scopus)
148 Downloads (Pure)

Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex

Marrott, N., Marshall, J. J. T., Svergun, DI., Crennell, S., Hough, D. W., Van Den Elsen, J. & Danson, M., 1 Nov 2014, In : Biochemical Journal. 463, 3, p. 405-412 8 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
146 Downloads (Pure)
2013

Post-translational modification in the archaea: structural characterization of multi-enzyme complex lipoylation

Posner, M. G., Upadhyay, A., Crennell, S., Watson, A. J. A., Dorus, S., Danson, M. J. & Bagby, S., 15 Jan 2013, In : Biochemical Journal. 449, 2, p. 415-425 11 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
149 Downloads (Pure)

Structure of a bifunctional alcohol dehydrogenase involved in bioethanol generation in Geobacillus thermoglucosidasius

Extance, J., Crennell, S. J., Eley, K., Cripps, R., Hough, D. W. & Danson, M. J., Oct 2013, In : Acta Crystallographica Section D-Biological Crystallography. 69, 10, p. 2104-2115 12 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
121 Downloads (Pure)
18 Citations (Scopus)

Temperature and the catalytic activity of enzymes: a fresh understanding

Daniel, R. M. & Danson, M. J., 2013, In : FEBS Letters. 17, 2, p. 2738-2743

Research output: Contribution to journalArticle

57 Citations (Scopus)
2012

The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly

Marrott, N. L., Marshall, J. J. T., Svergun, D. I., Crennell, S. J., Hough, D. W., Danson, M. J. & van den Elsen, J. M. H., Mar 2012, In : FEBS Journal. 279, 5, p. 713-723 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2011

Contribution of inter-subunit interactions to the thermostability of Pyrococcus furiosus citrate synthase

Moore, V., Kanu, A., Byron, O., Campbell, G., Danson, M. J., Hough, D. W. & Crennell, S. J., May 2011, In : Extremophiles. 15, 3, p. 327-336 10 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
143 Downloads (Pure)
2010

A new understanding of how temperature affects the catalytic activity of enzymes

Daniel, R. M. & Danson, M. J., Oct 2010, In : Trends in Biochemical Sciences. 35, 10, p. 584-591 8 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Discovery of a putative acetoin dehydrogenase complex in the hyperthermophilic archaeon Sulfolobus solfataricus

Payne, K. A. P., Hough, D. W. & Danson, M. J., 19 Mar 2010, In : FEBS Letters. 584, 6, p. 1231-1234 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Metabolism of pentose sugars in the hyperthermophilic archaea sulfolobus solfataricus and sulfolobus acidocaldarius

Nunn, C. E. M., Johnsen, U., Schonheit, P., Fuhrer, T., Sauer, U., Hough, D. W. & Danson, M. J., 29 Oct 2010, In : Journal of Biological Chemistry. 285, 44, p. 33701-33709 9 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)
31 Citations (Scopus)

The molecular basis of the effect of temperature on enzyme activity

Daniel, R. M., Peterson, M. E., Danson, M. J., Price, N. C., Kelly, S. M., Monk, C. R., Weinberg, C. S., Oudshoorn, M. L. & Lee, C. K., 15 Jan 2010, In : Biochemical Journal. 425, 2, p. 353-360 8 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)
2009

A unique lipoylation system in the Archaea: lipoylation in Thermoplasma acidophilum requires two proteins

Posner, M. G., Upadhyay, A., Bagby, S., Hough, D. W. & Danson, M. J., Aug 2009, In : FEBS Journal. 276, 15, p. 4012-4022 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Engineering stereocontrol into aldolase catalyzed reactions

Bull, S. D., Danson, M. J., Hough, D. W. & Royer, S., 2009, In : Abstracts of Papers of the American Chemical Society. 238, 23-ORGN.

Research output: Contribution to journalArticle

Nitroreductase from Bacillus licheniformis:a stable enzyme for prodrug activation

Emptage, C. D., Knox, R. J., Danson, M. J. & Hough, D. W., 1 Jan 2009, In : Biochemical Pharmacology. 77, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Where to land on Mars

Cockell, C., Bridges, J., Dannatt, L., Burchell, M., Patel, M. & Danson, M., Dec 2009, In : Astronomy & Geophysics. 50, 6, p. 18-26 9 p.

Research output: Contribution to journalArticle

2008

Enzyme stability and activity at high temperatures

Daniel, R. M., Danson, M. J., Hough, D. W., Lee, C. K., Peterson, M. E. & Cowan, D. A., 2008, Protein adaptation in extremophiles. Siddiqui, K. S. & Thomas, T. (eds.). New York, U. S. A.: Nova Science Publishers, p. 1-34 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

The 2-oxoacid dehydrogenase multienzyme complex of Haloferax volcanii

Al-Mailem, D. M., Hough, D. W. & Danson, M. J., 2008, In : Extremophiles. 12, 1, p. 89-96 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

The effect of temperature on enzyme activity: new insights and their implications

Daniel, R. M., Danson, M. J., Eisenthal, R., Lee, C. K. & Peterson, M. E., 2008, In : Extremophiles. 12, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

The Equilibrium Model for the effect of temperature on enzymes - Insights and implications

Weinberg, C. S., Daniel, R. M., Monk, C. R., Danson, M. J. & Lee, C. K., 2008, In : Chimica Oggi-Chemistry Today. 26, 4, p. 14-15 2 p.

Research output: Contribution to journalArticle

The structure of Sulfolobus solfataricus 2-keto-3-deoxygluconate kinase

Potter, J. A., Kerou, M., Lamble, H. J., Bull, S. D., Hough, D. W., Danson, M. J. & Taylor, G. L., 2008, In : Acta Crystallographica Section D-Biological Crystallography. 64, p. 1283-1287 5 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2007

A thermostable aldolase for the synthesis of 3-deoxy-2-ulosonic acids

Lamble, H. J., Royer, S. F., Hough, D. W., Danson, M. J., Taylor, G. L. & Bull, S. D., 2007, In : Advanced Synthesis & Catalysis. 349, 6, p. 817-821 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Catalytic efficiency and k(cat)/K-M: a useful comparator?

Eisenthal, R., Danson, M. J. & Hough, D. W., 2007, In : Trends in Biotechnology. 25, 6, p. 247-249 3 p.

Research output: Contribution to journalArticle

170 Citations (Scopus)

Central metabolism

Danson, M. J., Lamble, H. J. & Hough, D. W., 2007, Archaea: Molecular and Cellular Biology. Cavicchioli, R. (ed.). Washington DC: ASM Press, p. 260-287 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Eurythermalism and the temperature dependence of enzyme activity

Lee, C. K., Daniel, R. M., Shepherd, C., Saul, D., Cary, S. C., Danson, M. J., Eisenthal, R. & Peterson, M. E., 2007, In : FASEB Journal. 21, 8, p. 1934-1941 8 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

New parameters controlling the effect of temperature on enzyme activity

Daniel, R. M., Danson, M. J., Eisenthal, R., Lee, C. K. & Peterson, M. E., 2007, In : Biochemical Society Transactions. 35, p. 1543-1546 4 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The 2-oxoacid dehydrogenase multi-enzyme complex of the archaeon Thermoplasma acidophilum - recombinant expression, assembly and characterization

Heath, C., Posner, M. G., Aass, H. C., Upadhyay, A., Scott, D. J., Hough, D. W. & Danson, M. J., 2007, In : FEBS Journal. 274, 20, p. 5406-5415 10 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

The dependence of enzyme activity on temperature: determination and validation of parameters

Peterson, M. E., Daniel, R. M., Danson, M. J. & Eisenthal, R., 2007, In : Biochemical Journal. 402, p. 331-337 7 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)
2006

The structural basis of substrate promiscuity in glucose dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus

Milburn, C. C., Lamble, H. J., Theodossis, A., Bull, S. D., Hough, D. W., Danson, M. J. & Taylor, G. L., 23 Mar 2006, In : Journal of Biological Chemistry. 281, 21, p. 14796-14804 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

The thermal behaviour of enzyme activity: implications for biotechnology

Eisenthal, R., Peterson, M. E., Daniel, R. M. & Danson, M. J., 1 Jul 2006, In : Trends in Biotechnology. 24, 7, p. 289-292 4 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
2005

Engineering stereocontrol into an aldolase-catalysed reaction

Lamble, H. J., Danson, M. J., Hough, D. W. & Bull, S. D., 2005, In : Chemical Communications. 2005, 1, p. 124-126 3 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
5 Citations (Scopus)

Promiscuity in the Archaea. The enzymology of metabolic pathways

Danson, M. J. & Hough, D. W., 2005, In : The Biochemist. 27, p. 17-21 5 p.

Research output: Contribution to journalArticle

Promiscuity in the part-phosphorylative Entner-Doudoroff pathway of the archaeon Sulfolobus solfataricus

Lamble, H. J., Theodossis, A., Milburn, C. C., Taylor, G. L., Bull, S., Hough, D. W. & Danson, M. J., 19 Dec 2005, In : FEBS Letters. 579, 30, p. 6865-6869 5 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2004

A new intrinsic thermal parameter for enzymes reveals true temperature optima

Peterson, M. E., Eisenthal, R., Danson, M. J., Spence, A. & Daniel, R. M., May 2004, In : Journal of Biological Chemistry. 279, 20, p. 20717-20722 6 p.

Research output: Contribution to journalArticle

66 Citations (Scopus)
17 Citations (Scopus)

Gluconate dehydratase from the promiscuous Entner-Doudoroff pathway in Sulfolobus solfataricus

Lamble, F. J., Milburn, C. C., Taylor, G. L., Hough, D. W. & Danson, M. J., 2004, In : FEBS Letters. 576, 1-2, p. 133-136 4 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Multienzyme complexes in the Archaea: predictions from genome sequences

Danson, M. J., Morgan, D. J., Jeffries, A. C., Hough, D. W. & Dyall-Smith, M. L., 2004, Halophilic Microorganisms. Ventosa, A. (ed.). Springer, p. 177-191 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter