Projects per year
Personal profile
Research interests
Based in the Department of Chemistry at the University of Bath, the Grayson Group’s research interests are centred around the use of molecular modelling and artificial intelligence to study organic and biological reactions.
Current research areas include:
Automation and artificial intelligence
Reaction modelling
Computational reaction design
In silico toxicology & drug design
Willing to supervise PhD
Please get in touch to discuss Master’s, PhD and Postdoctoral research opportunities.
Education/Academic qualification
Chemistry, Doctor of Philosophy, University of Cambridge
2010 → 2014
Chemistry, Master of Natural Science, University of Cambridge
2009 → 2010
Natural Sciences, Bachelor of Arts, University of Cambridge
2006 → 2009
External positions
Lindemann Trust Fellow, University of California, Los Angeles
1 Jan 2015 → 31 Dec 2015Junior Research Fellow, University of Cambridge
1 Oct 2014 → 30 Jun 2018Keywords
- Computational Chemistry
- Machine Learning
- Molecular Modelling
- Organic Chemistry
- Organocatalysis
- Transition Metal Catalysis
- Toxicology
Fingerprint Dive into the research topics where Matthew Grayson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Hydrogen bonds
Chemical Compounds
Catalysts
Chemical Compounds
Enantioselectivity
Chemical Compounds
Density functional theory
Chemical Compounds
Phosphoric acid
Engineering & Materials Science
Cinchona
Chemical Compounds
Hydrogen Bonding
Medicine & Life Sciences
Stereoselectivity
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2019 2019
- 1 Finished
On-line tritiated water detection by in situ ATR-FTIR (phase 2)
Science & Technology Facilities Council (STFC)
7/05/19 → 31/07/19
Project: Research council
Research Output 2012 2019
- 18 Article
Vinylidene Homologation of Boronic Esters and its Application to the Synthesis of the Proposed Structure of Machillene
Fordham, J. M., Grayson, M. N. & Aggarwal, V. K., 21 Oct 2019, In : Angewandte Chemie-International Edition. 58, 43, p. 15268-15272 5 p.Research output: Contribution to journal › Article
3
Citations
(Scopus)
2
Downloads
(Pure)
Mechanistic Insights into a Chiral Phosphoric Acid-Catalyzed Asymmetric Pinacol Rearrangement
Falcone, B. N., Grayson, M. N. & Rodriguez, J. B., 7 Dec 2018, In : Journal of Organic Chemistry. 83, 23, p. 14683-14687 5 p.Research output: Contribution to journal › Article
Open Access
File
6
Citations
(Scopus)
Recent Developments and Applications of the Chiral Bronsted Acid Catalyzed Allylboration of Carbonyl Compounds
Sedgwick, D. M., Grayson, M. N., Fustero, S. & Barrio, P., 17 May 2018, In : Synthesis (Germany). 50, 10, p. 1935-1957 23 p.Research output: Contribution to journal › Article
Open Access
Carbonyl compounds
Acids
Alcohols
2
Citations
(Scopus)
Using Transition State Modeling to Predict Mutagenicity for Michael Acceptors
Allen, T. E. H., Grayson, M. N., Goodman, J. M., Gutsell, S. & Russell, P. J., 25 Jun 2018, In : Journal of Chemical Information and Modeling. 58, 6, p. 1266-1271 6 p.Research output: Contribution to journal › Article
Open Access
Covalent bonds
activation
Assays
DNA
energy
30
Citations
(Scopus)
Chronology of CH···O Hydrogen Bonding from Molecular Dynamics Studies of the Phosphoric Acid-Catalyzed Allylboration of Benzaldehyde
Grayson, M. N., Yang, Z. & Houk, K. N., 14 Jun 2017, In : Journal of the American Chemical Society. 139, 23, p. 7717-7720 4 p.Research output: Contribution to journal › Article
Open Access
Chronology
Phosphoric acid
Molecular Dynamics Simulation
Hydrogen Bonding
Molecular dynamics