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Accepting PhD Students

20012020
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Research Output 2001 2019

2019
6 Downloads (Pure)
Open Access
File
2018
4 Citations (Scopus)
46 Downloads (Pure)

Arginase overexpression and NADPH oxidase stimulation underlie impaired vasodilation induced by advanced glycation end products

El-bassossy, H. M., Neamatallah, T., Balamash, K. S., Abushareb, A. T. & Watson, M. L., 23 May 2018, In : Biochemical and Biophysical Research Communications. 499, 4, p. 992-997 6 p.

Research output: Contribution to journalArticle

Open Access
File
Arginase
Advanced Glycosylation End Products
NADPH Oxidase
Vasodilation
Aorta
2017
2 Citations (Scopus)

Zingerone alleviates the delayed ventricular repolarization and AV conduction in diabetes: Effect on cardiac fibrosis and inflammation

El-bassossy, H. M., Al-Thubiani, W. S., Elberry, A. A., Mujallid, M. I., Ghareib, S. A., Azhar, A. S., Banjar, Z. M. & Watson, M. L., 1 Dec 2017, In : PLoS ONE. 12, 12, e0189074.

Research output: Contribution to journalArticle

Open Access
Medical problems
fibrosis
diabetes
Fibrosis
inflammation
2016
5 Citations (Scopus)
129 Downloads (Pure)

Cardioprotection by 6-gingerol in diabetic rats

El-Bassossy, H. M., Elberry, A. A., Ghareib, S. A., Azhar, A., Banjar, Z. M. & Watson, M. L., 2 Sep 2016, In : Biochemical and Biophysical Research Communications. 477, 4, p. 908-914

Research output: Contribution to journalArticle

Open Access
File
Rats
Hemodynamics
Streptozocin
Medical problems
Drug therapy
8 Citations (Scopus)
178 Downloads (Pure)

Protective effect of zingerone on increased vascular contractility in diabetic rat aorta

Ghareib, S. A., El-Bassossy, H. M., Elberry, A. A., Azar, A., Watson, M. L., Banjar, Z. M. & Alahdal, A. M., 5 Jun 2016, In : European Journal of Pharmacology. 780, p. 174-179 6 p.

Research output: Contribution to journalArticle

Open Access
File
2015
20 Citations (Scopus)
84 Downloads (Pure)

6-Gingerol alleviates exaggerated vasoconstriction in diabetic rat aorta through direct vasodilation and nitric oxide generation

Ghareib, S. A., El-Bassossy, H. M., Elberry, A. A., Azhar, A., Watson, M. L. & Banjar, Z. M., 9 Nov 2015, In : Drug Design, Development and Therapy. 9, p. 6019-6026 7 p.

Research output: Contribution to journalArticle

Open Access
File
Vasoconstriction
Vasodilation
Aorta
Nitric Oxide
Advanced Glycosylation End Products
21 Citations (Scopus)
110 Downloads (Pure)
Open Access
File
Xanthine Oxidase
Angiotensins
Insulin Resistance
Insulin
Inflammation
2014
4 Citations (Scopus)
52 Downloads (Pure)

Phosphoinositide 3-Kinase Alpha-Dependent Regulation of Branching Morphogenesis in Murine Embryonic Lung: Evidence for a Role in Determining Morphogenic Properties of FGF7

Carter, E., Miron-Buchacra, G., Goldoni, S., Danahay, H., Westwick, J., Watson, M. L., Tosh, D. & Ward, S. G., 2 Dec 2014, In : PLoS ONE. 9, 12, p. 1-22 22 p., e113555.

Research output: Contribution to journalArticle

Open Access
1-Phosphatidylinositol 4-Kinase
phosphatidylinositol 3-kinase
Phosphatidylinositols
Morphogenesis
morphogenesis
2013
42 Citations (Scopus)
100 Downloads (Pure)

Arginase inhibition alleviates hypertension in the metabolic syndrome

El-Bassossy, H. M., El-Fawal, R., Fahmy, A. & Watson, M. L., Jun 2013, In : British Journal of Pharmacology. 169, 3, p. 693-703 11 p.

Research output: Contribution to journalArticle

Open Access
File
Arginase
Hypertension
Acetylcholine
Blood Pressure
Citrulline
2012
34 Citations (Scopus)
Infrared lasers
Speckle
Lasers
Imaging techniques
Perfusion
2011
42 Citations (Scopus)

Expression and agonist responsiveness of CXCR3 variants in human T lymphocytes

Korniejewska, A., McKnight, A. J., Johnson, Z., Watson, M. L. & Ward, S. G., Apr 2011, In : Immunology. 132, 4, p. 503-515 13 p.

Research output: Contribution to journalArticle

T-Lymphocytes
CXCR3 Receptors
Phosphorylation
Ligands
Chemokine Receptors
2010
3 Citations (Scopus)

Analysis of CXCR3 and atypical variant expression and signalling in human T lymphocytes

Korniejewska, A., Watson, M. L. & Ward, S. G., 2010, T-Cell Trafficking. Marelli-Berg, F. M. & Nourshargh, S. (eds.). Humana Press, Vol. 606. p. 125-147 23 p. (Methods in Molecular Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

T-Lymphocytes
Chemokines
Chemokine CXCL11
Chemokine CXCL9
Anti-Inflammatory Agents
2009
20 Citations (Scopus)

Haem oxygenase-1 induction protects against tumour necrosis factor α impairment of endothelial-dependent relaxation in rat isolated pulmonary artery

El-Bassossy, H. M., El-Maraghy, N. N., El-Fayoumi, H. M. & Watson, M. L., Nov 2009, In : British Journal of Pharmacology. 158, 6, p. 1527-1535 9 p.

Research output: Contribution to journalArticle

Heme Oxygenase (Decyclizing)
Pulmonary Artery
Tumor Necrosis Factor-alpha
Hemin
Nitric Oxide
2008
11 Citations (Scopus)
Cyclic GMP
Pulmonary Artery
Lipopolysaccharides
Aorta
Type 5 Cyclic Nucleotide Phosphodiesterases
30 Citations (Scopus)

Interleukin 13 increases contractility of murine tracheal smooth muscle by a phosphoinositide 3-kinase p110δ-dependent mechanism

Farghaly, H. S. M., Blagbrough, I. S., Medina-Tato, D. A. & Watson, M. L., May 2008, In : Molecular Pharmacology. 73, 5, p. 1530-1537 8 p.

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Interleukin-13
Smooth Muscle
Protein Isoforms
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one

The effect of PI3K inhibition on IL-13-induced arginase I expression in mice tracheal segments

Farghaly, H., Causton, B., Blagbrough, I. & Watson, M. L., 2008, In : Fundamental & Clinical Pharmacology. 22, p. 14-14 1 p.

Research output: Contribution to journalArticle

2007
49 Citations (Scopus)

Phosphoinositide 3-kinase signalling in lung disease: leucocytes and beyond

Medina-Tato, D. A., Ward, S. G. & Watson, M. L., 2007, In : Immunology. 121, p. 448-461 14 p.

Research output: Contribution to journalArticle

2006

Cross-regulation between class IA phosphatidyl inositol 3-kinase p110 beta and p110 delta isoforms

Medina-Tato, D. A., Ward, S. G. & Watson, M. L., 2006, In : Inflammation Research. 55, Suppl 2, p. S124-S124

Research output: Contribution to journalArticle

Exploring the role for protein arginine methylation in chemokine signalling and migration of human T-lymphocytes

Korniejewska, A., Watson, M. L. & Ward, S. G., 2006.

Research output: Contribution to conferencePaper

Heme oxygenase-1 protects against tumour necrosis factor-? and interleukin-1? induced hyporesponsiveness to ach in the rat pulmonary artery

El-Bassossy, H., El-Maraghi, N., El-Fayomi, H. & Watson, M. L., 2006.

Research output: Contribution to conferencePaper

17 Citations (Scopus)

Leukocyte navigation mechanisms as targets in airway diseases

Medina-Tato, D. A., Watson, M. L. & Ward, S. G., 2006, In : Drug Discovery Today. 11, 19-20, p. 866-879 14 p.

Research output: Contribution to journalArticle

Mechanisms of LPS-induced changes in vascular reactivity to endothelin 1 in rat aortic and pulmonary vessels

El-Awady, M. S., Smirnov, S. V. & Watson, M. L., 2006, In : pA2Online. 4, 2, p. 020P

Research output: Contribution to journalArticle

2005
27 Citations (Scopus)
2003

Disparate effects of PPAR g ligands on PI3K and MAPK signalling pathways

Patel, K. M., Whittaker, P., Watson, M. L. & Ward, S. G., 2003, In : Inflammation Research. Supplement 2, p. S174

Research output: Contribution to journalArticle

2002
8 Citations (Scopus)

Chemokines - linking receptors to response

Watson, M. L., 2002, In : Arthritis & Rheumatism. 105, p. 121-124 4 p.

Research output: Contribution to journalArticle

The effect of HO-1 induction on the post-ischaemic recovery of the isolated rat heart

Reidy, V., Watson, M. L. & Woodward, B., 2002, In : British Journal of Pharmacology. 135, p. 140P

Research output: Contribution to journalArticle

The regulation of cyclooxygenase in tracheal epithelial cell lines

Williams, S., Ward, S. G. & Watson, M. L., 2002, In : Pediatric Pulmonology. 231, p. S22

Research output: Contribution to journalArticle

2001

Phosphoinositide 3-kinase and PTEN activity in airway epithelial cells

Lavelle, M. J., Smith, A. W., Ward, S. G. & Watson, M. L., 2001, In : Pediatric Pulmonology. S22, p. 196-197 2 p.

Research output: Contribution to journalArticle