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Acyl Coenzyme A Chemical Compounds
Assays Chemical Compounds
Coenzyme A Medicine & Life Sciences
Ibuprofen Chemical Compounds
Prostatic Neoplasms Medicine & Life Sciences
Substrates Chemical Compounds
Pharmaceutical Preparations Chemical Compounds
Esters Medicine & Life Sciences

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Projects 2015 2018

Research Output 2011 2018

Structure-activity relationships of rationally designed AMACR 1A inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 30 Apr 2018 In : Bioorganic and Medicinal Chemistry. 79, p. 145-154 10 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Enzyme activity
Coenzyme A
Assays
Esters

A convenient colorimetric assay for α-methylacyl-CoA racemase (AMACR; P504S) and testing of inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 21 Apr 2017 (Unpublished)

Research output: Contribution to conferenceAbstract

File
Coenzyme A
Inhibitory Concentration 50
Acyl Coenzyme A
Prostatic Neoplasms
S 10
2 Citations

A novel colorimetric assay for α-methylacyl-CoA racemase 1A (AMACR; P504S) utilizing the elimination of 2,4-dinitrophenolate

Jevglevskis, M., Lee, G. L., Nathubhai, A., Petrova, Y., James, T., Threadgill, M., Woodman, T. & Lloyd, M. 7 May 2017 In : Chemical Communications. 53, 37, p. 5087-5090 4 p.

Research output: Contribution to journalArticle

Open Access
Assays
Ibuprofen
Fatty acids
Fatty Acids
Degradation

High-Throughput Screening to identify novel inhibitors of human α-methylacyl-CoA racemase 1A (AMACR; P504S)

Petrova, Y., Mattan, H., Lee, G. L., Jevglevskis, M., Woodman, T. & Lloyd, M. 21 Apr 2017

Research output: Contribution to conferencePoster

Libraries
Prostatic Neoplasms
Pharmaceutical Preparations
Acyl Coenzyme A
Ibuprofen

Methods (amacr)

Lloyd, M., Jevglevskis, M., Lee, G. L., Woodman, T. & Threadgill, M. 22 Jun 2017 3 Feb 2014

Research output: Patent