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Accepting Doctoral Students

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Personal profile

Research interests

Maisem is a Lecturer in the Department of Biology & Biochemistry, University of Bath. His main areas of research centre around bacteria defined as ‘pathobionts’, microorganisms that normally colonises the human host asymptomatically but possess the capacity to cause severe infection. One of his main interests involve Staphylococcus aureus, a bacterial pathogen that is a master at performing this deadly art. Historically, the switch between coloniser and pathogen was attributed to the immune status of the patient. However, in the last two decades S aureus has been causing severe infections in healthy individuals, the reasons for which are poorly understood. Furthermore, the rise of antibiotic resistance in S aureus and the lack of effective vaccines are further complicating these infections. Therefore, we are in urgent need of novel intervention strategies to curtail this threat and thus require a deeper understanding of this host – pathobiont relationship. 

My area of research focuses on how S aureus escapes host immunity, aiming to unravel and characterise major immune evasion mechanisms to inform future therapeutic intervention. In addition, my group is interested in both understanding how S aureus evolves resistance to antibiotics and in testing and characterising novel antimicrobials with the potential to limit infections. We use a wide variety of state-of-the-art molecular microbiological techniques and bioinformatics to understand the molecular mechanisms promoting virulence and resistance to antibiotics. 

 

Willing to supervise doctoral students

Experience working in a microbiology/ immunobiology or molecular biology is preferred but not essential. We are seeking candidates with a strong interest in host-pathogen interactions with motivation to explore and better understand the molecular basis of pathogen immune evasion. 

Education/Academic qualification

Natural Sciences, Bachelor of Science, Trinity College Dublin

1 Oct 20051 Jun 2009

Award Date: 1 Jul 2009

Molecular Medical Microbiology, Master in Science, University of Nottingham

1 Oct 200930 Sep 2010

External positions

Postdoctoral Research Fellow, Lund University

1 Jun 201730 Nov 2018

Research Fellow, Fundació Institut Investigació Germans (IGTP) Trias i Pujol, Barcelona, Spain

1 Mar 201631 May 2017

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