• 5 WEST 3.06


Research output per year

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Personal profile

Research interests

We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.

Education/Academic qualification

Doctor of Philosophy, University of Cambridge

Award Date: 1 Jan 2002

Bachelor of Science, University of Liverpool

Award Date: 1 Jan 1998


  • medicinal chemistry
  • drug design and synthesis

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Research Output

  • 33 Article
  • 1 Book/Film/Article review

Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells

Alexander, B. E., Sun, S., Palframan, M. J., Kociok-Köhn, G., Dibwe, D. F., Watanabe, S., Caggiano, L., Awale, S. & Lewis, S. E., 7 Jan 2020, In : ChemMedChem. 15, 1, p. 125-135 11 p.

Research output: Contribution to journalArticle

Open Access
27 Downloads (Pure)

The enone motif of (+)-grandifloracin is not essential for 'anti-austerity' antiproliferative activity

Ali Khan, M., Wood, P. J., Lamb-Guhren, N. M., Caggiano, L., Kociok-Köhn, G., Tosh, D. & Lewis, S. E., 1 Jul 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 13, p. 2815-2819 5 p.

Research output: Contribution to journalArticle

Open Access
  • 8 Citations (Scopus)
    126 Downloads (Pure)

    Book Review: An introduction to medicinal chemistry (5th edition)

    Caggiano, L., 15 Aug 2013, Chemistry World.

    Research output: Contribution to specialist publicationBook/Film/Article review

    Design, synthesis and antiproliferative activity of indole analogues of indanocine.

    Tunbridge, G. A., Oram, J. & Caggiano, L., 2013, In : MedChemComm. 4, 11, p. 1452-1456

    Research output: Contribution to journalArticle

    Open Access
  • 19 Citations (Scopus)
    120 Downloads (Pure)

    Mild and efficient capture and functionalisation of CO2 using silver(I) oxide and application to 13C-labelled dialkyl carbonates

    Tunbridge, G. A., Baruchello, R. & Caggiano, L., 14 Apr 2013, In : RSC Advances. 3, 14, p. 4613-4621 9 p.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Citations (Scopus)
    236 Downloads (Pure)