Projects per year
Personal profile
Research interests
We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.
Education/Academic qualification
Doctor of Philosophy, University of Cambridge
Award Date: 1 Jan 2002
Bachelor of Science, Chemistry and Industrial Chemistry, University of Liverpool
Award Date: 1 Jan 1998
Keywords
- medicinal chemistry
- drug design and synthesis
Fingerprint
Dive into the research topics where Lorenzo Caggiano is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Finished
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Characterisation of the Role of NADPH Oxidase 1 in Collagen-Dependent Activiation of Platelets: A Potential Target for the Development of Novel Antithrombotics
Pula, G. (PI) & Caggiano, L. (CoI)
1/12/15 → 30/11/18
Project: UK charity
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ACADEMIC FELLOWSHIPS
Caggiano, L. (PI)
Engineering and Physical Sciences Research Council
8/01/07 → 7/01/12
Project: Research council
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Grandifloridin D: A Potent Antiausterity Agent Targeting Pancreatic Cancer Cells via Akt/mTOR and Autophagy Inhibition
Nguyen, H. H., Maneenet, J., Fujii, T., Caggiano, L., Lewis, S. E. & Awale, S., 20 Nov 2025, In: Biological and Pharmaceutical Bulletin. 48, 11, p. 1784-1793 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
Total Synthesis of a Pancratistatin/Shikimic Acid Hybrid Analogue
Azubuike, D., Di Iulio, G. A. & Caggiano, L., 19 Feb 2024, In: European Journal of Organic Chemistry. 27, 7, 7 p., e202301247.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (SciVal) -
Exploring Convergent Two-Step Synthetic Approaches to the Pancratistatin Framework
Di Iulio, G. A., Mahon, M. F. & Caggiano, L., 19 Aug 2022, In: ChemistrySelect. 7, 31, e202202703.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects
Vara, D., Tarafdar, A., Celikag, M., Patinha, D., Gulacsy, C. E., Hounslea, E., Warren, Z., Ferreira, B., Koeners, M. P., Caggiano, L. & Pula, G., 1 Oct 2020, In: FASEB Journal. 34, 10, p. 13959-13977 19 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Citations (SciVal) -
Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells
Alexander, B. E., Sun, S., Palframan, M. J., Kociok-Köhn, G., Dibwe, D. F., Watanabe, S., Caggiano, L., Awale, S. & Lewis, S. E., 7 Jan 2020, In: ChemMedChem. 15, 1, p. 125-135 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (SciVal)175 Downloads (Pure)
Activities
- 1 Public talk, lecture, debate, seminar, workshop
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School visit
Caggiano, L. (Speaker)
19 Jun 2025Activity: Public, Community and School Engagement › Public talk, lecture, debate, seminar, workshop