Projects per year
Personal profile
Research interests
We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.
Education/Academic qualification
Doctor of Philosophy, University of Cambridge
Award Date: 1 Jan 2002
Bachelor of Science, University of Liverpool
Award Date: 1 Jan 1998
Keywords
- medicinal chemistry
- drug design and synthesis
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Network
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Projects
- 3 Finished
GW4-AF9 – 011: GW4-BCR (Brain Cancer Research) From Daffodils to Drugs
3/09/18 → 31/10/19
Project: Research-related funding
ACADEMIC FELLOWSHIPS
Engineering and Physical Sciences Research Council
8/01/07 → 7/01/12
Project: Research council
Research Output
Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells
Alexander, B. E., Sun, S., Palframan, M. J., Kociok-Köhn, G., Dibwe, D. F., Watanabe, S., Caggiano, L., Awale, S. & Lewis, S. E., 7 Jan 2020, In : ChemMedChem. 15, 1, p. 125-135 11 p.Research output: Contribution to journal › Article
Open Access
File
24
Downloads
(Pure)
The enone motif of (+)-grandifloracin is not essential for 'anti-austerity' antiproliferative activity
Ali Khan, M., Wood, P. J., Lamb-Guhren, N. M., Caggiano, L., Kociok-Köhn, G., Tosh, D. & Lewis, S. E., 1 Jul 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 13, p. 2815-2819 5 p.Research output: Contribution to journal › Article
Open Access
File
8
Citations
(Scopus)
123
Downloads
(Pure)
Book Review: An introduction to medicinal chemistry (5th edition)
Caggiano, L., 15 Aug 2013, Chemistry World.Research output: Contribution to specialist publication › Book/Film/Article review
Design, synthesis and antiproliferative activity of indole analogues of indanocine.
Tunbridge, G. A., Oram, J. & Caggiano, L., 2013, In : MedChemComm. 4, 11, p. 1452-1456Research output: Contribution to journal › Article
Open Access
File
19
Citations
(Scopus)
116
Downloads
(Pure)
Mild and efficient capture and functionalisation of CO2 using silver(I) oxide and application to 13C-labelled dialkyl carbonates
Tunbridge, G. A., Baruchello, R. & Caggiano, L., 14 Apr 2013, In : RSC Advances. 3, 14, p. 4613-4621 9 p.Research output: Contribution to journal › Article
Open Access
File
2
Citations
(Scopus)
232
Downloads
(Pure)
Thesis
Chalcone derivatives in cancer research and tissue engineering
Author: Ciupa, A., 28 Feb 2013Supervisor: Caggiano, L. (Supervisor) & De Bank, P. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Design, Synthesis and Biological Evaluation of Narciclasine Analogues
Author: Griffiths, N., 29 Sep 2015Supervisor: Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Developing in vitro and in silico tools to predict the impact of gastrointestinal disease states on drug product performance
Author: Effinger, A., 19 Feb 2020Supervisor: Fotaki, N. (Supervisor), O'Driscoll, C. M. O. (External person) (Supervisor), McAllister, M. (External person) (Supervisor) & Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
Efficient synthesis of biologically active small molecules
Author: Tunbridge, G., 11 Dec 2012Supervisor: Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Pancreatic cancer drug discovery based upon (+)-grandifloracin
Author: Alexander, B., 3 Apr 2019Supervisor: Caggiano, L. (Supervisor) & Lewis, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD