Lorenzo Caggiano

Senior Lecturer, Department of Pharmacy & Pharmacology

Phone+44 (0) 1225 385709
EmailL.Caggiano@bath.ac.uk

5 WEST 3.06

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Personal profile

Research interests

We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.

Education/Academic qualification

Doctor of Philosophy, University of Cambridge

Bachelor of Science, University of Liverpool

Keywords

medicinal chemistry
drug design and synthesis

Fingerprint Dive into the research topics where Lorenzo Caggiano is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

1 Similar Profiles

Derivatives Chemical Compounds

Biological Products Chemical Compounds

Iodides Chemical Compounds

Cross Reactions Medicine & Life Sciences

Cells Chemical Compounds

Bioactivity Chemical Compounds

Cell Line Medicine & Life Sciences

Prenylation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2007 2019

3 Finished

GW4-AF9 – 011: GW4-BCR (Brain Cancer Research) From Daffodils to Drugs

Caggiano, L.

3/09/18 → 31/10/19

Project: Research-related funding

Characterisation of the Role of NADPH Oxidase 1 in Collagen-Dependent Activiation of Platelets: A Potential Target for the Development of Novel Antithrombotics

Pula, G. & Caggiano, L.

British Heart Foundation

1/12/15 → 30/11/18

Project: UK charity

ACADEMIC FELLOWSHIPS

Caggiano, L.

Engineering and Physical Sciences Research Council

8/01/07 → 7/01/12

Project: Research council

Research Output 2002 2019

33 Article
1 Book/Film/Article review

1 Downloads (Pure)

Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells

Alexander, B. E., Sun, S., Palframan, M. J., Kociok-Köhn, G., Dibwe, D. F., Watanabe, S., Caggiano, L., Awale, S. & Lewis, S. E., 10 Dec 2019, In : ChemMedChem. 15, 1, p. 125-135 11 p.

Research output: Contribution to journal › Article

Open Access

File

8 Citations (Scopus)

98 Downloads (Pure)

The enone motif of (+)-grandifloracin is not essential for 'anti-austerity' antiproliferative activity

Ali Khan, M., Wood, P. J., Lamb-Guhren, N. M., Caggiano, L., Kociok-Köhn, G., Tosh, D. & Lewis, S. E., 1 Jul 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 13, p. 2815-2819 5 p.

Research output: Contribution to journal › Article

Open Access

File

Biological Products

HT29 Cells

Functional groups

grandifloracin

Book Review: An introduction to medicinal chemistry (5th edition)

Caggiano, L., 15 Aug 2013, Chemistry World.

Research output: Contribution to specialist publication › Book/Film/Article review

19 Citations (Scopus)

89 Downloads (Pure)

Design, synthesis and antiproliferative activity of indole analogues of indanocine.

Tunbridge, G. A., Oram, J. & Caggiano, L., 2013, In : MedChemComm. 4, 11, p. 1452-1456

Research output: Contribution to journal › Article

Open Access

File

Cells

Cell Line

Neoplasms

indanocine

indole

2 Citations (Scopus)

174 Downloads (Pure)

Mild and efficient capture and functionalisation of CO₂ using silver(I) oxide and application to ¹³C-labelled dialkyl carbonates

Tunbridge, G. A., Baruchello, R. & Caggiano, L., 14 Apr 2013, In : RSC Advances. 3, 14, p. 4613-4621 9 p.

Research output: Contribution to journal › Article

Open Access

File

Carbonates

Carbon Monoxide

Silver

Oxides

Iodides