Projects per year
Personal profile
Research interests
We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Cambridge
Award Date: 1 Jan 2002
Bachelor of Science, Chemistry and Industrial Chemistry, University of Liverpool
Award Date: 1 Jan 1998
Keywords
- medicinal chemistry
- drug design and synthesis
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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Characterisation of the Role of NADPH Oxidase 1 in Collagen-Dependent Activiation of Platelets: A Potential Target for the Development of Novel Antithrombotics
Pula, G. (PI) & Caggiano, L. (CoI)
1/12/15 → 30/11/18
Project: UK charity
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ACADEMIC FELLOWSHIPS
Caggiano, L. (PI)
Engineering and Physical Sciences Research Council
8/01/07 → 7/01/12
Project: Research council
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Total Synthesis of a Pancratistatin/Shikimic Acid Hybrid Analogue
Azubuike, D., Di Iulio, G. A. & Caggiano, L., 19 Feb 2024, In: European Journal of Organic Chemistry. 27, 7, 7 p., e202301247.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Exploring Convergent Two-Step Synthetic Approaches to the Pancratistatin Framework
Di Iulio, G. A., Mahon, M. F. & Caggiano, L., 19 Aug 2022, In: ChemistrySelect. 7, 31, e202202703.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
NADPH oxidase 1 is a novel pharmacological target for the development of an antiplatelet drug without bleeding side effects
Vara, D., Tarafdar, A., Celikag, M., Patinha, D., Gulacsy, C. E., Hounslea, E., Warren, Z., Ferreira, B., Koeners, M. P., Caggiano, L. & Pula, G., 29 Sept 2020, In: FASEB Journal. 34, 10, p. 13969-13977 9 p.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (SciVal) -
Sidechain Diversification of Grandifloracin Allows Identification of Analogues with Enhanced Anti-Austerity Activity against Human PANC-1 Pancreatic Cancer Cells
Alexander, B. E., Sun, S., Palframan, M. J., Kociok-Köhn, G., Dibwe, D. F., Watanabe, S., Caggiano, L., Awale, S. & Lewis, S. E., 7 Jan 2020, In: ChemMedChem. 15, 1, p. 125-135 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (SciVal)127 Downloads (Pure) -
Stuart Warren (24 Dec 1938-22 Mar 2020)
Aggarwal, V. K., Armstrong, S. K., Caggiano, L., Chibale, K., Clayden, J., Coldham, I., Greeves, N., Hartley, R. C., Knight, J. G., Kuhnert, N., Mitchell, H. J., Nelson, A., O'Brien, P., Thomas, S. P. & Wyatt, P., 30 Sept 2020, In: Organic & Biomolecular Chemistry. 18, 37, p. 7236-7237 2 p.Research output: Contribution to journal › Article › peer-review