Projects per year
Personal profile
Research interests
We have various research interests and our main goal is the efficient synthesis of simplified analogues
of natural products, compounds obtained from nature which display various biological activities, as potential leads for potential therapeutics.
Education/Academic qualification
Doctor of Philosophy, University of Cambridge
Bachelor of Science, University of Liverpool
Keywords
- medicinal chemistry
- drug design and synthesis
Fingerprint Dive into the research topics where Lorenzo Caggiano is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
Derivatives
Chemical Compounds
Biological Products
Chemical Compounds
Iodides
Chemical Compounds
Cross Reactions
Medicine & Life Sciences
Cells
Chemical Compounds
Bioactivity
Chemical Compounds
Cell Line
Medicine & Life Sciences
Prenylation
Medicine & Life Sciences
Projects 2007 2018
- 2 Finished
ACADEMIC FELLOWSHIPS
Engineering and Physical Sciences Research Council
8/01/07 → 7/01/12
Project: Research council
Research Output 2002 2014
- 32 Article
7
Citations
(Scopus)
61
Downloads
(Pure)
The enone motif of (+)-grandifloracin is not essential for 'anti-austerity' antiproliferative activity
Ali Khan, M., Wood, P. J., Lamb-Guhren, N. M., Caggiano, L., Kociok-Köhn, G., Tosh, D. & Lewis, S. E., 1 Jul 2014, In : Bioorganic & Medicinal Chemistry Letters. 24, 13, p. 2815-2819 5 p.Research output: Contribution to journal › Article
Open Access
File
Biological Products
HT29 Cells
Functional groups
grandifloracin
18
Citations
(Scopus)
58
Downloads
(Pure)
Design, synthesis and antiproliferative activity of indole analogues of indanocine.
Tunbridge, G. A., Oram, J. & Caggiano, L., 2013, In : MedChemComm. 4, 11, p. 1452-1456Research output: Contribution to journal › Article
Open Access
File
Cells
Cell Line
Neoplasms
indanocine
indole
2
Citations
(Scopus)
95
Downloads
(Pure)
Mild and efficient capture and functionalisation of CO2 using silver(I) oxide and application to 13C-labelled dialkyl carbonates
Tunbridge, G. A., Baruchello, R. & Caggiano, L., 14 Apr 2013, In : RSC Advances. 3, 14, p. 4613-4621 9 p.Research output: Contribution to journal › Article
Open Access
File
Carbonates
Carbon Monoxide
Silver
Oxides
Iodides
4
Citations
(Scopus)
55
Downloads
(Pure)
Multicellular aggregation of maltol-modified cells triggered by Fe3+ ions
Ciupa, A., De Bank, P. A. & Caggiano, L., 7 Nov 2013, In : Chemical Communications. 49, 86, p. 10148-10150 3 p.Research output: Contribution to journal › Article
Open Access
File
Agglomeration
Ions
maltol
18
Citations
(Scopus)
Synthesis and antiproliferative activity of some 3-(pyrid-2-yl)-pyrazolines
Ciupa, A., De Bank, P. A., Mahon, M. F., Wood, P. J. & Caggiano, L., 1 Jun 2013, In : MedChemComm. 4, 6, p. 956-961 6 p.Research output: Contribution to journal › Article
Lead compounds
Cells
X Ray Crystallography
Tubulin
Tumor Cell Line
Thesis
Chalcone derivatives in cancer research and tissue engineering
Author: Ciupa, A., 28 Feb 2013Supervisor: Caggiano, L. (Supervisor) & De Bank, P. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Design, Synthesis and Biological Evaluation of Narciclasine Analogues
Author: Griffiths, N., 29 Sep 2015Supervisor: Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Efficient synthesis of biologically active small molecules
Author: Tunbridge, G., 11 Dec 2012Supervisor: Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File
Pancreatic cancer drug discovery based upon (+)-grandifloracin
Author: Alexander, B., 3 Apr 2019Supervisor: Caggiano, L. (Supervisor) & Lewis, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
Synthesis and evaluation of narciclasine analogues
Author: Judd, K., 1 Feb 2011Supervisor: Caggiano, L. (Supervisor)
Student thesis: Doctoral Thesis › PhD
File