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Lauren Cowley

Dr

  • MILNER CENTRE 1.17

Accepting PhD Students

20152018
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Personal profile

Research interests

My work aims to mitigate significant public health problems in infectious diseases using bioinformatics and the latest sequencing technologies. I learned the value of this while working at Public Health England and being involved in the implementation of the routine use of whole genome sequencing for surveillance and investigation of gastrointestinal bacteria in the UK. I also learned the potential of using the latest sequencing technologies while using portable nanopore sequencing for the Ebola epidemic. My current work centres around improving bacterial GWAS techniques for investigating phenotypes of significance to public health and also developing machine learning techniques for classifying antibiotic and phage resistance from sequencing data.

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Research Output 2015 2018

Evolution via recombination: Cell-to-cell contact facilitates larger recombination events in Streptococcus pneumoniae

Cowley, L., Petersen, F. C., Junges, R., Jimenez, M. J. D., Morrison, D. A. & Hanage, W. P., 13 Jun 2018, In : Plos Genetics. 14, 6, p. 1-23 23 p., e1007410.

Research output: Contribution to journalArticle

Open Access

Phylogenetic comparison of enteroinvasive Escherichia coli isolated from cases of diarrhoeal disease in England, 2005–2016

Cowley, L., Oresegun, D. R., Chattaway, M. A., Dallman, T. J. & Jenkins, C., 1 Jun 2018, In : Journal of Medical Microbiology. 67, 6, p. 884-888

Research output: Contribution to journalArticle

1 Citations

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157

Cowley, L., Low, A. S., Pickard, D., Boinett, C. J., Dallman, T. J., Day, M., Perry, N., Gally, D. L., Parkhill, J., Jenkins, C. & Cain, A. K., 5 Sep 2018, In : mBio. 9, 4, 15 p., e00705-18.

Research output: Contribution to journalArticle

Open Access

Within-host Mycobacterium tuberculosis diversity and its utility for inferences of transmission

Martin, M. A., Lee, R. S., Cowley, L., Gardy, J. L. & Hanage, W. P., 11 Oct 2018, In : Microbial Genomics. 4

Research output: Contribution to journalArticle

Open Access