Photo of Lauren Cowley

Lauren Cowley

Dr

  • MILNER CENTRE 1.17

Accepting PhD Students

20152019
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Personal profile

Research interests

My work aims to mitigate significant public health problems in infectious diseases using bioinformatics and the latest sequencing technologies. I learned the value of this while working at Public Health England and being involved in the implementation of the routine use of whole genome sequencing for surveillance and investigation of gastrointestinal bacteria in the UK. I also learned the potential of using the latest sequencing technologies while using portable nanopore sequencing for the Ebola epidemic. My current work centres around improving bacterial GWAS techniques for investigating phenotypes of significance to public health and also developing machine learning techniques for classifying antibiotic and phage resistance from sequencing data.

Fingerprint Dive into the research topics where Lauren Cowley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Public Health Medicine & Life Sciences
Nanopores Medicine & Life Sciences
Technology Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Microbial Drug Resistance Medicine & Life Sciences
Computational Biology Medicine & Life Sciences
England Medicine & Life Sciences
Bacteriophages Medicine & Life Sciences

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Research Output 2015 2019

Phage predation shapes the population structure of Shiga-toxigenic Escherichia coli O157:H7 in the UK: An evolutionary perspective

Cowley, L. A., Dallman, T. J., Jenkins, C. & Sheppard, S. K., 30 Aug 2019, In : Frontiers in Genetics. 10, JUL, p. 1-7 7 p., 763.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Temperate Bacteriophages from Chronic Pseudomonas aeruginosa Lung Infections Show Disease-Specific Changes in Host Range and Modulate Antimicrobial Susceptibility

Tariq, M. A., Everest, F. L. C., Cowley, L. A., Wright, R., Holt, G. S., Ingram, H., Duignan, L. A. M., Nelson, A., Lanyon, C. V., Perry, A., Perry, J. D., Bourke, S., Brockhurst, M. A., Bridge, S. H., De Soyza, A. & Smith, D. L., 4 Jun 2019, In : mSystems. 4, 4, e00191-18.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Evolution via recombination: Cell-to-cell contact facilitates larger recombination events in Streptococcus pneumoniae

Cowley, L., Petersen, F. C., Junges, R., Jimenez, M. J. D., Morrison, D. A. & Hanage, W. P., 13 Jun 2018, In : Plos Genetics. 14, 6, p. 1-23 23 p., e1007410.

Research output: Contribution to journalArticle

Open Access

Phylogenetic comparison of enteroinvasive Escherichia coli isolated from cases of diarrhoeal disease in England, 2005–2016

Cowley, L., Oresegun, D. R., Chattaway, M. A., Dallman, T. J. & Jenkins, C., 1 Jun 2018, In : Journal of Medical Microbiology. 67, 6, p. 884-888 5 p., 000739.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157

Cowley, L., Low, A. S., Pickard, D., Boinett, C. J., Dallman, T. J., Day, M., Perry, N., Gally, D. L., Parkhill, J., Jenkins, C. & Cain, A. K., 24 Jul 2018, In : mBio. 9, 4, p. 1-15 15 p., e00705-18.

Research output: Contribution to journalArticle

Open Access