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20062022
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Research Output 2006 2019

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Article
2019
1 Citation (Scopus)

Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance

Rienecker, K. D. A., Chavasse, A. T., Moorwood, K., Ward, A. & Isles, A. R., 29 Apr 2019, In : Genes, Brain and Behavior. e12571.

Research output: Contribution to journalArticle

Open Access
2015
115 Citations (Scopus)

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Goodson, W. H., Lowe, L., Carpenter, D. O., Gilbertson, M., Manaf Ali, A., Lopez de Cerain Salsamendi, A., Lasfar, A., Carnero, A., Azqueta, A., Amedei, A., Charles, A. K., Collins, A. R., Ward, A., Salzberg, A. C., Colacci, A., Olsen, A-K., Berg, A., Barclay, B. J., Zhou, B. P., Blanco-Aparicio, C. & 153 others, Baglole, C. J., Dong, C., Mondello, C., Hsu, C-W., Naus, C. C., Yedjou, C., Curran, C. S., Laird, D. W., Koch, D. C., Carlin, D. J., Felsher, D. W., Roy, D., Brown, D. G., Ratovitski, E., Ryan, E. P., Corsini, E., Rojas, E., Moon, E-Y., Laconi, E., Marongiu, F., Al-Mulla, F., Chiaradonna, F., Darroudi, F., Martin, F. L., Van Schooten, F. J., Goldberg, G. S., Wagemaker, G., Nangami, G. N., Calaf, G. M., Williams, G., Wolf, G. T., Koppen, G., Brunborg, G., Lyerly, H. K., Krishnan, H., Ab Hamid, H., Yasaei, H., Sone, H., Kondoh, H., Salem, H. K., Hsu, H-Y., Park, H. H., Koturbash, I., Miousse, I. R., Scovassi, A. I., Klaunig, J. E., Vondráček, J., Raju, J., Roman, J., Wise, J. P., Whitfield, J. R., Woodrick, J., Christopher, J. A., Ochieng, J., Martinez-Leal, J. F., Weisz, J., Kravchenko, J., Sun, J., Prudhomme, K. R., Narayanan, K. B., Cohen-Solal, K. A., Moorwood, K., Gonzalez, L., Soucek, L., Jian, L., D'Abronzo, L. S., Lin, L-T., Li, L., Gulliver, L., McCawley, L. J., Memeo, L., Vermeulen, L., Leyns, L., Zhang, L., Valverde, M., Khatami, M., Romano, M. F., Chapellier, M., Williams, M. A., Wade, M., Manjili, M. H., Lleonart, M. E., Xia, M., Gonzalez, M. J., Karamouzis, M. V., Kirsch-Volders, M., Vaccari, M., Kuemmerle, N. B., Singh, N., Cruickshanks, N., Kleinstreuer, N., van Larebeke, N., Ahmed, N., Ogunkua, O., Krishnakumar, P. K., Vadgama, P., Marignani, P. A., Ghosh, P. M., Ostrosky-Wegman, P., Thompson, P. A., Dent, P., Heneberg, P., Darbre, P., Sing Leung, P., Nangia-Makker, P., Cheng, Q. S., Robey, R. B., Al-Temaimi, R., Roy, R., Andrade-Vieira, R., Sinha, R. K., Mehta, R., Vento, R., Di Fiore, R., Ponce-Cusi, R., Dornetshuber-Fleiss, R., Nahta, R., Castellino, R. C., Palorini, R., Abd Hamid, R., Langie, S. A. S., Eltom, S. E., Brooks, S. A., Ryeom, S., Wise, S. S., Bay, S. N., Harris, S. A., Papagerakis, S., Romano, S., Pavanello, S., Eriksson, S., Forte, S., Casey, S. C., Luanpitpong, S., Lee, T-J., Otsuki, T., Chen, T., Massfelder, T., Sanderson, T., Guarnieri, T., Hultman, T., Dormoy, V., Odero-Marah, V., Sabbisetti, V., Maguer-Satta, V., Rathmell, W. K., Engström, W., Decker, W. K., Bisson, W. H., Rojanasakul, Y., Luqmani, Y., Chen, Z. & Hu, Z., Jun 2015, In : Carcinogenesis. 36 Suppl 1, p. S254-S296

Research output: Contribution to journalArticle

Open Access
Carcinogenesis
Neoplasms
Chemical Safety
Research
International Agencies
18 Citations (Scopus)

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling

Engström, W., Darbre, P., Eriksson, S., Gulliver, L., Hultman, T., Karamouzis, M. V., Klaunig, J. E., Mehta, R., Moorwood, K., Sanderson, T., Sone, H., Vadgama, P., Wagemaker, G., Ward, A., Singh, N., Al-Mulla, F., Al-Temaimi, R., Amedei, A., Colacci, A. M., Vaccari, M. & 12 others, Mondello, C., Scovassi, A. I., Raju, J., Hamid, R. A., Memeo, L., Forte, S., Roy, R., Woodrick, J., Salem, H. K., Ryan, E. P., Brown, D. G. & Bisson, W. H., Jun 2015, In : Carcinogenesis. 36 , Suppl 1, p. S38-S60

Research output: Contribution to journalArticle

Cell Proliferation
Neoplasms
Growth
2014
13 Citations (Scopus)
115 Downloads (Pure)

Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1 genes

Madon-Simon, M., Cowley, M., Garfield, A. S., Moorwood, K. & Ward, A., 31 Dec 2014, In : BMC Biology. 12, 22 p., 771.

Research output: Contribution to journalArticle

Open Access
File
Physiology
fetal development
Fetal Development
physiology
Genes
32 Citations (Scopus)
50 Downloads (Pure)

Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup

Cowley, M., Garfield, A. S., Madon-Simon, M., Charalambous, M., Clarkson, R. W., Smalley, M. J., Kendrick, H., Isles, A. R., Parry, A. J., Carney, S., Oakey, R. J., Heisler, L. K., Moorwood, K., Wolf, J. B. & Ward, A., 28 Feb 2014, In : PLoS Biology. 12, 2, p. 1-13 13 p., e1001799.

Research output: Contribution to journalArticle

Open Access
pups
health status
Health Status
Growth
Fats
2012
48 Citations (Scopus)

High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells

Turinetto, V., Orlando, L., Sanchez Ripoll, Y., Kumpfmueller, B., Storm, M. P., Porcedda, P., Minieri, V., Saviozzi, S., Accomasso, L., Cibrario Rocchietti, E., Moorwood, K., Circosta, P., Cignetti, A., Welham, M. J. & Giachino, C., 1 Jul 2012, In : Stem Cells. 30, 7, p. 1414-1423

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Pluripotent Stem Cells
Histones
Phosphorylation
Double-Stranded DNA Breaks
2011
120 Citations (Scopus)

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

Garfield, A. S., Cowley, M., Smith, F. M., Moorwood, K., Stewart-Cox, J. E., Gilroy, K., Baker, S., Xia, J., Dalley, J. W., Hurst, L. D., Wilkinson, L. S., Isles, A. R. & Ward, A., 27 Jan 2011, In : Nature. 469, 7331, p. 534-538 5 p.

Research output: Contribution to journalArticle

alleles
social behavior
embryogenesis
genes
social dominance
2010

DKK1 and GPCRX, two new transgenic mouse models for innovative Alzheimer's disease drug discovery

Manfredi, G., Moorwood, K., Stewart-Cox, J., Withington, I. & Ward, A., Feb 2010, In : Genetics Research. 92, 1, p. 74-75 2 p.

Research output: Contribution to journalArticle

2009
107 Citations (Scopus)
91 Downloads (Pure)

Frequent long-range epigenetic silencing of Protocadherin gene clusters on chromosome 5q31 in Wilms' Tumor

Dallosso, A. R., Hancock, A. L., Szemes, M., Moorwood, K., Chilukamarri, L., Tsai, H. H., Sarkar, A., Barasch, J., Vuononvirta, R., Jones, C., Pritchard-Jones, K., Royer-Pokora, B., Lee, S. B., Owen, C., Malik, S., Feng, Y., Frank, M., Ward, A., Brown, K. W. & Malik, K., 26 Nov 2009, In : Plos Genetics. 5, 11, 13 p., e1000745.

Research output: Contribution to journalArticle

File
Wilms Tumor
cadherins
Multigene Family
multigene family
Epigenomics
2007
53 Citations (Scopus)

Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer

Dallosso, A. R., Hancock, A. L., Malik, S., Salpekar, A., King-Underwood, L., Pritchard-Jones, K., Peters, J., Moorwood, K., Ward, A., Malik, K. T. A. & Brown, K. W., 2007, In : RNA. 13, 12, p. 2287-2299 13 p.

Research output: Contribution to journalArticle

2006
12 Citations (Scopus)
Tumor Suppressor Proteins
Wilms Tumor
Spermatogenesis
Transgenic Mice
Protein Isoforms