Research Output per year
Research Output per year
Personal profile
Research interests
My research interests focus on host-microbe interactions and the study of pathogenesis, diagnosis and control of bacterial infections.
My emphasis is on elucidating host-microbe interactions in probiotic bacteria by investigating mechanisms of interactions in modulation of epithelial cell health, and in neurotransmitter signalling in the gut.
Another area of my research interest is in studying pathogenesis, diagnosis and prevention of Medical device associated infections. A particular focus on catheter associated urinary tract infections (CAUTI), and the use of bacteriophages (bacterial viruses) therapy to control these infections. Furthermore I am studying the role of efflux systems in bacterial virulence and pathogenesis in CAUTI; efflux systems are target for development of antimicrobial agents.
In addition, I have been interested in studying pathogenesis and diagnosis of wound infections using novel ex vivo wound models, quantification of bacterial toxin gene expression, and use of third generation genome sequencing techniques for early detection of infection.
Education/Academic qualification
Pharmacy & Biomolecular Sciences, Doctor of Science, University of Brighton
15 Jan 2010 → 22 May 2014
Award Date: 29 Jan 2019
Biotechnology, Master of Science, University of Strathclyde
28 Sep 2007 → 30 Aug 2008
Award Date: 8 Nov 2008
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Research Output
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An In Vitro Bladder Model for Studying Catheter- Associated Urinary Tract Infection and Associated Analysis of Biofilms
Nzakizwanayo, J., Pelling, H., Milo, S. & Jones, B., 16 Jul 2019, Proteus mirabilis - Methods and Protocols. Pearson, M. (ed.). Springer Nature, p. 139-158 20 p. (Methods in Molecular Biology; vol. 2021).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Bacterial biofilm formation on indwelling urethral catheters
Pelling, H., Nzakizwanayo, J., Milo, S., Denham, E. L., MacFarlane, W. M., Bock, L. J., Sutton, J. M. & Jones, B. V., 1 Apr 2019, In: Letters in Applied Microbiology. 68, 4, p. 277-293 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)40 Downloads (Pure) -
De-repression of the smvA efflux system arises in clinical isolates of Proteus mirabilis and reduces susceptibility to chlorhexidine and other biocides
Pelling, H., Bock, L. J., Nzakizwanayo, J., Wand, M. E., Denham, E. L., MacFarlane, W. M., Sutton, J. M. & Jones, B. V., 21 Nov 2019, In: Antimicrobial Agents and Chemotherapy. 63, 12, p. 1-15 15 p., e01535-19.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Emerging medical and engineering strategies for the prevention of long-term indwelling catheter blockage
Milo, S., Nzakizwanayo, J., Hathaway, H. J., Jones, B. V. & Jenkins, A. T. A., 1 Jan 2019, In: Proceedings of the Institution of Mechanical Engineers, Part H - Journal of Engineering in Medicine. 233, 1, p. 68-83 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)197 Downloads (Pure) -
Genomic and Ecogenomic Characterization of Proteus mirabilis Bacteriophages
Jones, B. & Nzakizwanayo, J., 6 Aug 2019, In: Frontiers in Microbiology. 10, p. 1-14 14 p., 1783.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus)