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Research interests

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John joined the Department for Health at the University of Bath in 2016 as a 50th Anniversary Prize Fellow to develop a research program in exercise immunology and oncology. John is collaborating with Bath Royal United Hospital, and national and international collaborators, to investigate how exercise augments anti-cancer immunity. In particular, a main focus of John's research is understanding how physical activity reduces the incidence of clinically-diagnosed cancers in humans. Another focus of John's research is to determine how exercise affects cancer immunotherapy, and John is currently leading a Cancer Research UK Pioneer Award exploring the impact of exercise on blood cancer immunotherapies.

John completed his PhD in 2010 at the School of Sport, Exercise and Rehabilitation Sciences at the University of Birmingham UK. During his PhD, John investigated the effects of exercise on vaccination responses in humans. Following his PhD, John undertook 6 years of post-doctoral training in blood cancers at the Institute of Immunology and Immunotherapy at the University of Birmingham Medical School. During this time, John was involved in the development of the first near-patient test for measuring free light chains (Seralite, Abingdon Health Ltd). Abingdon Health listed on AIM in 2020. John continues to undertake research in early diagnostics, biomarkers and assay development and is a member of the Centre for Biosensors, Bioelectronics and Biodevices at the University of Bath.

John has received funding as principle investigator from Cancer Research UK, the Medical Research Council, the World Cancer Research Fund, the Physiological Society and other funders. John has received funding as co-investigator from the National Insititute for Health Research, NASA, Cancer Research UK and other funders.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Keywords

  • Exercise
  • Cancer
  • Immunology
  • Physical Activity
  • Tumour
  • Blood
  • Haematology

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