Jody Mason

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  IMPACT - Creating an intracellular screening platform for cyclic peptide drug discovery

  Mason, J. (PI) & Tang, S. (Researcher CoI)

  Engineering and Physical Sciences Research Council

  1/11/24 → 31/12/25

  Project: Research council

• Revolver Therapeutics - Targeting AP-1 and DLX Transcription factors in paediatric gliomas

  Mason, J. (PI) & Jones, C. (CoI)

  1/09/24 → 31/08/26

  Project: UK industry

  • Transcription Factors 100%
  • DNA-binding Protein 100%

• Multi-user Transmission Electron Microscope

  gold, V. (PI) & Mason, J. (CoI)

  1/07/24 → 30/06/25

  Project: Research council

• An Intracellular Helix-constrained Peptide Library Screening Platform to Derive Functional Transcription Factor Antagonists

  Mason, J. (PI) & Van Den Elsen, J. (CoI)

  Biotechnology and Biological Sciences Research Council

  1/07/23 → 30/06/26

  Project: Research council

  • Transcription Factors 100%
  • Peptide Library 94%
  • Transcription 38%
  • Activating Transcription Factor 3 30%
  • Legumain 30%

• A Combined and Automated High Throughput Parallel Peptide Synthesis Platform.

  Mason, J. (PI)

  1/02/23 → 31/01/25

  Project: Research council

• A Combined and Automated High Throughput Parallel Peptide Synthesis Platform

  Mason, J. (PI), Kelsh, R. (CoI), Lovell, S. (CoI), Mehrban, N. (CoI), Mrsny, R. (CoI), Perry, T. (CoI), Van Den Elsen, J. (CoI), Dela Isla, J. (Researcher), Rodrigues, D. (Researcher) & Vennard, C. (Researcher)

  MRC

  31/10/22 → 30/10/25

  Project: Research council

  • Peptide Synthesis 100%
  • Biological Product 50%
  • Health Care Cost 50%
  • Protein-Protein Interaction 50%
  • High Throughput Screening 50%

• From Peptides to Mimetics: Towards Smaller More Stable Drug-like Protein-protein Interaction Inhibitors

  Mason, J. (PI)

  Biotechnology and Biological Sciences Research Council

  1/09/21 → 31/08/26

  Project: Research council

  • AP-1 Transcription Factor 100%
  • Malignant Neoplasm 86%
  • Transcription Factors 83%
  • Lactate Dehydrogenase 80%
  • DNA Binding 60%
• Not started

  ARUK Major Project Grant 2024 - Helical Stabilisers

  Mason, J. (PI) & Meade, R. (Researcher CoI)

  Alzheimer's Research UK

  1/05/25 → 31/10/27

  Project: UK charity

• Finished

  Creating complex topologies through post-translational modification of recombinant peptides

  Tang, S. (PI), Mason, J. (CoI) & Cresswell, A. (CoI)

  1/02/24 → 31/05/24

  Project: Research-related funding

• Antagonising an "undruggable" transcription factor

  Mason, J. (PI)

  1/06/23 → 30/11/23

  Project: Research-related funding

  • UK 100%
  • Transcription Factors 100%

• SET2 Executives into Business Award

  Mason, J. (PI)

  1/09/22 → 30/06/23

  Project: Research-related funding

• Irreversibly Silencing Oncogenic Master-regulator cMyc Using Library-derived Electrophilic Helical Peptides

  Mason, J. (PI) & Van Den Elsen, J. (CoI)

  MRC

  1/12/20 → 30/11/24

  Project: Research council

  • Malignant Neoplasm 100%
  • Transcription Factors 80%
  • AP-1 Transcription Factor 68%
  • Peptide Library 64%
  • Cancer Cell 64%

• Identification and Characterisation of Library Derived PPI Inhibitors

  Mason, J. (PI)

  1/08/20 → 31/07/23

  Project: Other

• ARUK Bristol and Bath Network

  Mason, J. (PI) & Van Den Elsen, J. (CoI)

  Alzheimer's Research UK

  1/01/20 → 30/04/20

  Project: UK charity

• Mining the (-)-epicatechin metabolome for Alzheimer's Therapeutics

  Williams, R. (PI) & Mason, J. (CoI)

  Alzheimer's Society

  2/09/19 → 1/07/22

  Project: UK charity

• A High Throughput Screen to Derive Functional Antagonists of Transcription Factor Cancer Targets.

  Mason, J. (PI)

  Cancer Research UK

  1/12/18 → 31/08/21

  Project: UK charity

• Alzheimer Society Funded Studentship - Intracellular Library Screening to Derive Novel Peptide-based Inhibitors of Toxicity in Alzheimer's disease

  Mason, J. (PI) & Williams, R. (PI)

  1/10/18 → 30/09/21

  Project: UK charity

  • Alzheimer's Disease 100%
  • Doctor of Philosophy 100%

• A Generalised Approach to Derive Functionally Active Peptide Inhibitors of Transcription Factor Activity

  Mason, J. (PI)

  Biotechnology and Biological Sciences Research Council

  1/10/18 → 30/06/22

  Project: Research council

  • AP-1 Transcription Factor 100%
  • Transcription Factors 80%
  • Peptide Library 59%
  • Transcription 51%
  • Signal Transduction 36%

• GW4 Biomed MRC DTP: Polyphenols as inhibitors of tau toxicity: protecting neuronal network function in AD

  Williams, R. (PI), Mason, J. (CoI) & Brown, J. (CoI)

  1/10/18 → 1/04/22

  Project: Research council

• Intracellular Library Screening to Drive Novel Peptide-based Inhibitors of Toxicity in Alzheimer's Disease

  Mason, J. (PI)

  Alzheimer's Society

  1/10/18 → 30/04/22

  Project: UK charity

• Downside Cell Derived Peptides

  Mason, J. (PI) & Williams, R. (CoI)

  Alzheimer's Research UK

  1/09/18 → 30/06/23

  Project: UK charity

• Identification and Characterisation of Peptide Modulators of Selected Protein: Protein Interactions

  Mason, J. (PI)

  Sapience Therapeutics Inc

  1/05/18 → 31/07/20

  Project: Other

• Live cell imaging capability for studying synaptic dysfunction, microglial migration and neuroprotection in Alzheimer's Disease

  Williams, R. (PI), Licchesi, J. (CoI), Mason, J. (CoI) & Van Den Elsen, J. (CoI)

  Alzheimer's Research UK

  1/04/18 → 31/03/19

  Project: UK charity

• CSCT MRes Student Project: Labeled Peptides For Parkinson’s Diagnostics

  Mason, J. (PI) & James, T. (CoI)

  16/10/17 → 31/05/18

  Project: Research-related funding

• Rational Design and Mimetic Refinement of an Intracellular-Drived Peptide: Deriving Potent Antagonists of Alapha-Synuclein Toxicity

  Mason, J. (PI) & Williams, R. (CoI)

  BRACE

  1/02/17 → 31/01/20

  Project: UK charity

• Establishing an Approach for the Selection and Design of Secondary Structure Mimetics to Antagonise Protein-Protein Interactions

  Mason, J. (PI)

  Engineering and Physical Sciences Research Council

  1/05/15 → 31/12/18

  Project: Research council

  • Coiled Coil 100%
  • Protein-Protein Interaction 92%
  • AP-1 Transcription Factor 86%
  • Basic Leucine Zipper Transcription Factor 74%
  • Peptide Library 74%

• Using Digital Art to Raise Awareness of Alzheimer's Disease

  Mason, J. (PI)

  The Wellcome Trust

  1/02/15 → 30/06/15

  Project: UK charity

• Iterative Design, Randomisation, Selection, Truncaqtion and Characterisation to Generate Small High Affinity Antagonists of the Activator Protein-1 Motif

  Mason, J. (PI)

  Cancer Research UK

  1/02/15 → 31/08/16

  Project: UK charity

  • Coiled Coil 100%
  • Protein-Protein Interaction 83%
  • AP-1 Transcription Factor 74%
  • Peptide Library 74%
  • Protease 55%