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Personal profile

Research interests

I am an applied mathematician developing and analysing mathematical models to address problems arising in the healthcare arena. Specifically, my current research focusses in two areas: control of infectious diseases; and drug monitoring and delivery particularly across the skin barrier. 

The role of mathematical modelling to explore infectious disease control is well-established and involves a wide range of modelling approaches. My particular interest is to explore the potential for classic techniques such as optimal control and feedback control to contribute to the literature in this field. My goal is to find an approach to control that might be easily translated into practice and that might result in clearly defined outcomes in terms of the levels of infection post control intervention. Most of my work is based on underlying deterministic infectious disease processes although I have also undertaken some work that is based upon stochastic and network models. 

 

My work on drug monitoring and delivery focuses on drugs that are delivered or monitored across the skin.  The challenge here is to work out how the drug molecules might partition and move through the skin barrier that is highly heterogeneous in nature. Here I work with systems of reaction diffusion advection equations for which parameter estimates can be made using the empirical studies of my collaborators working in the Department of Pharmacy & Pharmacology. The resulting mechanistic models diverge from classical pharmacokinetic (PK) models of drug delivery but are of increasing interest to colleagues working in the Pharmaceutical industries who are aware of the limitations of a purely PK approach. Linked to this activity, I am a member of the UK network for Quantitative Systems Pharmacology.

 

Teaching interests

I have a long-standing interest in Widening Participation in HE. In my own work with students at the university, I am interested in developing effective learning environments to support the diverse needs of students. I also have a strong track record of working at the School-University transition. Currently this involves a collaboration with the AMSP (https://amsp.org.uk) to encourage students from the state school sector to study mathematics post-16 (A level and Core Mathematics).

Other responsibilities

Chair of Academic Assembly (2018-2021)

Ex-officio  member of Senate, Council and Court

Head of Natural Sciences (2019 - )

Member of the London Mathematical Society (LMS) education committee (2014-2020)

Inaugural chair of the LMS TEMAC sub-committee which has oversight of promoting teaching mathematics as a career to undergraduate students studying mathematics in the UK (2019 - )

Founding director of MASH (https://www.bath.ac.uk/professional-services/mathematics-resources-centre-mash/), the institutional mathematics resources centre that offers a wide range of activities to support the  mathematical and statistical needs of all members of the university. 

Willing to supervise PhD

Mechanistic mathematical models for drug delivery and monitoring.

Control of infectious diseases.

Education/Academic qualification

Applied Mathematics, Doctor of Philosophy, University of Washington

Secondary Mathematics Teaching, King's College London

External positions

Chair, LMS TEMAC sub-committee, London Mathematical Society

Sep 2019 → …

External Examiner UG Mathematics Penrhyn Campus, University of Exeter

Sep 2017Jul 2020

Holgate Lecturer, London Mathematical Society

Sep 2015Jun 2017

Mathematics Subject Expert, Skills Testing Agency

Jun 2015Jun 2016

Education Committee member, London Mathematical Society

Sep 2014Sep 2020

External Examiner UG Mathematics, University of Ulster

Sep 2013Jul 2016

Outer Circle Member, Advisory Committee on Mathematics Education

Jan 2013Dec 2016

Vice-Chair, Loughborough University

Sep 2012Aug 2013

External Examiner UG Mathematics Modules, University of Cumbria

Sep 2006Jul 2009

Fingerprint Dive into the research topics where Jane White is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

wolves Agriculture & Biology
Vaccination Mathematics
Optimal Control Mathematics
Infection Mathematics
Virus Mathematics
Theoretical Models Medicine & Life Sciences
Papillomaviridae Medicine & Life Sciences
Drugs Mathematics

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2000 2021

AMSP assistant area coordinator

White, J.

1/09/1830/04/20

Project: UK charity

MASAMU 2018

White, J.

14/11/1825/11/18

Project: UK charity

MASAMU 2017

White, J.

15/11/1723/11/17

Project: UK charity

IMI Academic Visitor Scheme

White, J.

5/09/1614/09/16

Project: Research-related funding

Research Output 1995 2018

2 Citations (Scopus)

Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis

Malinzi, J., Ouifki, R., Eladdadi, A., Torres, D. F. M. & White, K. A. J., 1 Dec 2018, In : Mathematical Biosciences and Engineering. 15, 6, p. 1435-1463 29 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
108 Downloads (Pure)

A mechanistic approach to modelling the formation of a drug reservoir in the skin

Jones, J. G., White, K. A. J. & Delgado-Charro, M. B., 1 Nov 2016, In : Mathematical Biosciences. 281, p. 36-45 10 p.

Research output: Contribution to journalArticle

Open Access
File
Skin
Drugs
drugs
Modeling
Pharmaceutical Preparations
4 Citations (Scopus)

Optimal control of integrodifference equations in a pest-pathogen system

Martinez, M. V., Lenhart, S. & White, K. A. J., 1 Aug 2015, In : Discrete and Continuous Dynamical Systems - Series B. 20, 6, p. 1759-1783 25 p.

Research output: Contribution to journalArticle

Integrodifference Equations
Pathogens
Optimal Control
Costs
Sweep
6 Citations (Scopus)
Chlamydia Infections
Chlamydia
Infection
Optimal Control
Contact Tracing
3 Citations (Scopus)
Chlamydia trachomatis
Control Strategy
Costs and Cost Analysis
Tracing
Costs

Thesis

Control of infectious diseases using a range of model structures parameterised for chlamydia

Author: Clarke, J., 20 Feb 2014

Supervisor: White, K. (Supervisor)

Student thesis: Doctoral ThesisPhD

Development and validation of a physiologically-based pharmacokinetic model for dermal absorption

Author: Maciel Tabosa, M., 19 Apr 2019

Supervisor: Guy, R. (Supervisor), Delgado-Charro, M. (Supervisor) & White, K. (Supervisor)

Student thesis: Doctoral ThesisPhD

File

Exploring the impact of heterogeneities on HIV dynamics within host

Author: Ward, Z., 1 Dec 2011

Supervisor: White, K. (Supervisor)

Student thesis: Doctoral ThesisPhD

File

Modelling healthcare provision for an infectious disease using optimal control

Author: Brown, V., 28 Feb 2010

Supervisor: White, K. (Supervisor)

Student thesis: Doctoral ThesisPhD

File

Modelling the Skin and Systemic Dispositions of Amino Acids to Assess the Potential for Transdermal, Non-Invasive Monitoring: Phenylalanine as a Case Study

Author: Woodford, A., 26 Apr 2017

Supervisor: White, K. (Supervisor) & Guy, R. (Supervisor)

Student thesis: Doctoral ThesisPhD

File