Projects per year
Personal profile
Research interests
Together with my research group, we carry out cutting-edge, internationally competitive pharmaceutical science within a School of Pharmacy. We aim to answer key questions in my areas of interest which are:
- molecular pharmaceutics, especially controlling polymers for drug and siRNA delivery
- gene delivery and gene silencing
- applied pharmaceutical analysis
- phytochemical (natural products) research
- target-led synthetic pharmaceutical and biological chemistry
- collaborative research with regard to molecular pharmacology of inflammation, cancer, and CNS diseases
We apply pharmaceutical analysis and phytochemistry to the research areas of molecular pharmaceutics and medicinal chemistry in our design and control of novel nanoparticles for siRNA, gene, and drug delivery, nanomedicine based on lipospermines and biocompatible polymers using fluorescent probes which we have designed and prepared. We study these using confocal microscope analysis and cell biology (with Dr Charareh Pourzand).
We are also investigating nanofibres prepared by electrospinning to make novel controlled release devices(with Dr Paul De Bank).
We work on rational, target driven drug design in the area of polyamine conjugate analogue synthesis against cancer and for ligand-gated ion channel control, synthetic chemistry of target natural products with detailed pharmaceutical analysis.
We welcome applications from scientists with interests in pharmaceutical analysis, pharmaceutics, chemistry, and areas where the interdisciplinary approach will be successful. The support provided to students in the Blagbrough research group has recently been recognised with the Excellence in Doctoral Supervision Award 2016.
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Projects 2007 2015
- 3 Finished
Wellcome Trust - Harm Reduction in Drugs Services Guided by Phamaceutical Analysis
1/07/12 → 30/06/15
Project: UK charity
Research Method and the Role of the Undergraduate Research Programme
Sutton, J., Blagbrough, I., Millar, J. & Rogers, P.
1/09/10 → 31/03/12
Project: UK charity
Neuroprotectives from Medicinal Plants
The Association of Commonwealth Universities
1/12/07 → 30/06/08
Project: UK charity
Research Output 1994 2019
19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids
Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.Research output: Contribution to journal › Article
1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues
Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.Research output: Contribution to journal › Article
Analysis of synthetic cannabinoid agonists and their degradation products after combustion in a smoking simulator
Naqi, H. A., Pudney, C. R., Husbands, S. M. & Blagbrough, I. S., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3101-3107 7 p.Research output: Contribution to journal › Article
Synthetic Cannabinoid Receptor Agonists Detection using Fluorescence Spectral Fingerprinting
May, B., Naqi, H., Tipping, M., Scott, J., Husbands, S., Blagbrough, I. & Pudney, C., 15 Oct 2019, In : Analytical Chemistry. 91, 20, p. 12971-12979 9 p.Research output: Contribution to journal › Article
Additive effects of 3,4-methylenedioxymethamphetamine (MDMA) and compassionate imagery on self-compassion in recreational users of ecstasy
Kamboj, S. K., Wallden, Y. S. E., Falconer, C. J., Alotaibi, M. R. M., Blagbrough, I., Husbands, S. & Freeman, T., 6 Nov 2017, In : Mindfulness. 9, 4, p. 1134-1145 12 p.Research output: Contribution to journal › Article
Thesis
Design and development of pharmaceutical dosage forms for gene and siRNA delivery
Author: Ghonaim, H., 1 Sep 2008Supervisor: Blagbrough, I. (Supervisor)
Student thesis: Doctoral Thesis › PhD
Designing An Educational Intervention For Crack Users Depending On Pharmaceutical Analysis Results
Author: Shehab, M. Z., 9 Oct 2014Supervisor: Blagbrough, I. (Supervisor), Rowan, M. (Supervisor) & Scott, J. (Supervisor)
Student thesis: Doctoral Thesis › PhD
Impurity profiling of illicit drugs
Author: Alotaibi, M. R. M., 26 Apr 2017Supervisor: Blagbrough, I. (Supervisor) & Husbands, S. (Supervisor)
Student thesis: Doctoral Thesis › PhD
Medicinal chemistry of aminoglycosides
Author: Al Khzem, A., 13 Feb 2019Supervisor: Blagbrough, I. (Supervisor) & Woodman, T. (Supervisor)
Student thesis: Doctoral Thesis › MPhil
Molecular genetic analysis of secondary metabolite biosynthesis in cassava as an economic and nutritious plant
Author: Bayoumi, S., 1 Oct 2008Supervisor: Blagbrough, I. (Supervisor), Rowan, M. (Supervisor) & Beeching, J. (Supervisor)
Student thesis: Doctoral Thesis › PhD