Research Output per year
Research Output 2013 2015
2015
15
Citations
(Scopus)
107
Downloads
(Pure)
Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro
Paine, H. A., Nathubhai, A., Woon, E. C. Y., Sunderland, P. T., Wood, P. J., Mahon, M. F., Lloyd, M. D., Thompson, A. S., Haikarainen, T., Narwal, M., Lehtio, L. & Threadgill, M. D., 1 Sep 2015, In : Bioorganic and Medicinal Chemistry. 23, 17, p. 5891-5908 18 p.Research output: Contribution to journal › Article
Open Access
File
Tankyrases
Benzamides
Deprotonation
Molecular modeling
Niacinamide
2013
12
Citations
(Scopus)
97
Downloads
(Pure)
One-pot tandem Hurtley–retro-Claisen–cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs
Woon, E. C. Y., Sunderland, P. T., Paine, H. A., Lloyd, M. D., Thompson, A. S. & Threadgill, M. D., 1 Sep 2013, In : Bioorganic and Medicinal Chemistry. 21, 17, p. 5218-5227 10 p.Research output: Contribution to journal › Article
Open Access
File
Cyclization
3-nitrobenzoic acid
Poly(ADP-ribose) Polymerases
Water
Lead compounds