Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 9 Similar Profiles
Tankyrases Chemical Compounds
Molecular modeling Chemical Compounds
Benzamides Chemical Compounds
Deprotonation Chemical Compounds
Niacinamide Chemical Compounds
Cyclization Chemical Compounds
beta Catenin Chemical Compounds
Poly(ADP-ribose) Polymerases Chemical Compounds

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Research Output 2013 2015

12 Citations

Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitro

Paine, H. A., Nathubhai, A., Woon, E. C. Y., Sunderland, P. T., Wood, P. J., Mahon, M. F., Lloyd, M. D., Thompson, A. S., Haikarainen, T., Narwal, M., Lehtio, L. & Threadgill, M. D. 1 Sep 2015 In : Bioorganic and Medicinal Chemistry. 23, 17, p. 5891-5908 18 p.

Research output: Contribution to journalArticle

File
Tankyrases
Benzamides
Deprotonation
Molecular modeling
Niacinamide

Inhibitors of the tankyrases, triple-function targets in the cancer cell

Paine, H. A. 20 Mar 2014 (Unpublished) 326 p.

Research output: ThesisDoctoral Thesis

File
Tankyrases
Cells
Amines
Molecular modeling
Poly(ADP-ribose) Polymerases
10 Citations
Open Access
File
Cyclization
3-nitrobenzoic acid
Poly(ADP-ribose) Polymerases
Water
Lead compounds