Hans-Wilhelm Nützmann

Dr

  • MILNER CENTRE 0.17

Accepting Doctoral Students

20092020

Research output per year

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Research Output

2020

Active and repressed biosynthetic gene clusters have spatially distinct chromosome states

Nützmann, H-W., Doerr, D., Ramirez-Colmenero, A., Sotelo-Fonseca, J. E., Wegel, E., Di Stefano, M., Wingett, S. W., Fraser, P., Hurst, L., Fernandez-Valverde, S. L. & Osbourn, A., 16 Jun 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 24, p. 13800-13809 10 p.

Research output: Contribution to journalArticle

Open Access
File
53 Downloads (Pure)

Chromatin analysis of metabolic gene clusters in plants

Huang, A. C. & Nützmann, H-W., 23 Feb 2020, Plant Epigenetics and Epigenomics (2nd ed.). Spillane, C. & McKeown, P. (eds.). New York, U. S. A.: Humana Press, p. 129-146 (Methods in Molecular Biology; vol. 2093).

Research output: Chapter in Book/Report/Conference proceedingChapter

Integrating transposable elements in the 3D genome

Bousios, A., Nützmann, H. W., Buck, D. & Michieletto, D., 4 Feb 2020, In : Mobile DNA. 11, 1, 8.

Research output: Contribution to journalReview article

Open Access
File
17 Downloads (Pure)
2019

A specialized metabolic network selectively modulates Arabidopsis root microbiota

Huang, A. C., Jiang, T., Liu, Y. X., Bai, Y. C., Reed, J., Qu, B., Goossens, A., Nützmann, H. W., Bai, Y. & Osbourn, A., 10 May 2019, In : Science. 364, 6440, eaau6389.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
20 Downloads (Pure)

Light-Induced Artemisinin Biosynthesis Is Regulated by the bZIP Transcription Factor AaHY5 in Artemisia annua

Hao, X., Zhong, Y., Nützmann, H-W., Fu, X., Yan, T., Shen, Q., Ma, Y., Zhao, J., Osbourn, A., Li, L. & Tang, K., 1 Aug 2019, In : Plant & Cell Physiology. 60, 8, p. 1747-1760 14 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2018

Embracing the next generation of plant scientists

Hetherington, F. M. & Nützmann, H. W., 1 Jan 2018, In : New Phytologist. 217, 2, p. 504-506 3 p.

Research output: Contribution to journalArticle

Metabolic gene clusters in eukaryotes

Nützmann, H. W., Scazzocchio, C. & Osbourn, A., 23 Nov 2018, In : Annual Review of Genetics. 52, p. 159-183 25 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)
2016

Delineation of metabolic gene clusters in plant genomes by chromatin signatures

Yu, N., Nuetzmann, H-W., MacDonald, J. T., Moore, B., Field, B., Berriri, S., Trick, M., Rosser, S. J., Kumar, S. V., Freemont, P. S. & Osbourn, A., 18 Mar 2016, In : Nucleic Acids Research. 44, 5, p. 2255-2265 11 p.

Research output: Contribution to journalArticle

Open Access
25 Citations (Scopus)

Plant metabolic clusters - from genetics to genomics

Nuetzmann, H-W., Huang, A. & Osbourn, A., 11 Jul 2016, In : New Phytologist. 211, 3, p. 771-89 19 p.

Research output: Contribution to journalReview article

93 Citations (Scopus)
2015

Minimum Information about a Biosynthetic Gene cluster

Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., de Bruijn, I., Chooi, Y. H., Claesen, J., Coates, R. C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., Hadjithomas, M. & 134 others, Haines, A. S., Helfrich, E. J. N., Hillwig, M. L., Ishida, K., Jones, A. C., Jones, C. S., Jungmann, K., Kegler, C., Kim, H. U., Kötter, P., Krug, D., Masschelein, J., Melnik, A. V., Mantovani, S. M., Monroe, E. A., Moore, M., Moss, N., Nuetzmann, H-W., Pan, G., Pati, A., Petras, D., Reen, F. J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N. J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A. K., Balibar, C. J., Balskus, E. P., Barona-Gómez, F., Bechthold, A., Bode, H. B., Borriss, R., Brady, S. F., Brakhage, A. A., Caffrey, P., Cheng, Y-Q., Clardy, J., Cox, R. J., De Mot, R., Donadio, S., Donia, M. S., van der Donk, W. A., Dorrestein, P. C., Doyle, S., Driessen, A. J. M., Ehling-Schulz, M., Entian, K-D., Fischbach, M. A., Gerwick, L., Gerwick, W. H., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S. E., Ju, J., Katz, L., Kaysser, L., Klassen, J. L., Keller, N. P., Kormanec, J., Kuipers, O. P., Kuzuyama, T., Kyrpides, N. C., Kwon, H-J., Lautru, S., Lavigne, R., Lee, C. Y., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D. A., Moore, B. S., Moreira, L. M., Müller, R., Neilan, B. A., Nett, M., Nielsen, J., O'Gara, F., Oikawa, H., Osbourn, A., Osburne, M. S., Ostash, B., Payne, S. M., Pernodet, J-L., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J. M., Salas, J. A., Schmitt, E. K., Scott, B., Seipke, R. F., Shen, B., Sherman, D. H., Sivonen, K., Smanski, M. J., Sosio, M., Stegmann, E., Süssmuth, R. D., Tahlan, K., Thomas, C. M., Tang, Y., Truman, A. W., Viaud, M., Walton, J. D., Walsh, C. T., Weber, T., van Wezel, G. P., Wilkinson, B., Willey, J. M., Wohlleben, W., Wright, G. D., Ziemert, N., Zhang, C., Zotchev, S. B., Breitling, R., Takano, E. & Glöckner, F. O., 30 Sep 2015, In : Nature Chemical Biology. 11, 9, p. 625-631 7 p.

Research output: Contribution to journalArticle

Open Access
316 Citations (Scopus)
2014

Cytotoxic and antifungal activities of melleolide antibiotics follow dissimilar structure-activity relationships

Bohnert, M., Nuetzmann, H-W., Schroeckh, V., Horn, F., Dahse, H-M., Brakhage, A. A. & Hoffmeister, D., Sep 2014, In : Phytochemistry. 105, p. 101-8 8 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Fungal-Actinomycete Interactions - Wakening of Silent Fungal Secondary Metabolism Gene Clusters via Interorganismic Interactions

Schroeckh, V., Nützmann, H. W. & Brakhage, A. A., 5 May 2014, Natural Products: Discourse, Diversity, and Design. Osbourn, A., Goss, R. & Carter, G. T. (eds.). Wiley-Blackwell, p. 147-158 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Gene clustering in plant specialized metabolism

Nuetzmann, H-W. & Osbourn, A., Apr 2014, In : Current Opinion in Biotechnology. 26, p. 91-9 9 p.

Research output: Contribution to journalReview article

Open Access
105 Citations (Scopus)

Regulation of metabolic gene clusters in Arabidopsis thaliana

Nuetzmann, H-W. & Osbourn, A., 18 Dec 2014, In : New Phytologist. 205, 2, p. 503-510 8 p.

Research output: Contribution to journalArticle

Open Access
30 Citations (Scopus)
2013

Distinct amino acids of histone H3 control secondary metabolism in Aspergillus nidulans

Nuetzmann, H-W., Fischer, J., Scherlach, K., Hertweck, C. & Brakhage, A. A., Oct 2013, In : Applied and Environmental Microbiology. 79, 19, p. 6102-9 8 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

Regulatory cross talk and microbial induction of fungal secondary metabolite gene clusters

Nuetzmann, H-W., Schroeckh, V. & Brakhage, A. A., 2012, In : Methods in Enzymology. 517, p. 325-41 17 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011

Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation

Nuetzmann, H-W., Reyes-Dominguez, Y., Scherlach, K., Schroeckh, V., Horn, F., Gacek, A., Schümann, J., Hertweck, C., Strauss, J. & Brakhage, A. A., 23 Aug 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 34, p. 14282-7 6 p.

Research output: Contribution to journalArticle

180 Citations (Scopus)

Cytotoxic pheofungins from an engineered fungus impaired in posttranslational protein modification

Scherlach, K., Nuetzmann, H-W., Schroeckh, V., Dahse, H-M., Brakhage, A. A. & Hertweck, C., 10 Oct 2011, In : Angewandte Chemie-International Edition. 50, 42, p. 9843-7 5 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
2009

Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans

Schroeckh, V., Scherlach, K., Nuetzmann, H-W., Shelest, E., Schmidt-Heck, W., Schuemann, J., Martin, K., Hertweck, C. & Brakhage, A. A., 25 Aug 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 34, p. 14558-63 6 p.

Research output: Contribution to journalArticle

375 Citations (Scopus)