Gyles Cozier

Dr

20102018
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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 8 Similar Profiles
Peptidyl-Dipeptidase A Medicine & Life Sciences
Carbonic Anhydrase II Medicine & Life Sciences
Angiotensin-Converting Enzyme Inhibitors Medicine & Life Sciences
Carbonic Anhydrase Inhibitors Medicine & Life Sciences
Phosphatidylinositol Phosphates Medicine & Life Sciences
Polyphosphates Medicine & Life Sciences
Phosphoric Monoester Hydrolases Chemical Compounds
Catalytic Domain Medicine & Life Sciences

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Research Output 2010 2018

Crystal structures of sampatrilat and sampatrilat-Asp in complex with human ACE: a molecular basis for domain-selectivity

Cozier, G. E., Schwager, S. L., Sharma, R. K., Chibale, K., Sturrock, E. D. & Acharya, K. R., 24 Feb 2018, In : FEBS Journal.

Research output: Contribution to journalArticle

Open Access
Peptidyl-Dipeptidase A
Hydrophobic and Hydrophilic Interactions
Angiotensin-Converting Enzyme Inhibitors
Lysine
Catalytic Domain
1 Citations

Investigation into the Mechanism of Homo- and Heterodimerization of Angiotensin-Converting Enzyme

Abrie, J. A., Moolman, W. J. A., Cozier, G. E., Schwager, S. L. U., Acharya, K. R. & Sturrock, E. D., 1 Apr 2018, In : Molecular Pharmacology. 93, 4, p. 344-354

Research output: Contribution to journalArticle

Open Access
Hominidae
Peptidyl-Dipeptidase A
Dimerization
Renin-Angiotensin System
Testis

Molecular Basis for Multiple Omapatrilat Binding Sites within the ACE C-Domain: Implications for Drug Design.

Cozier, G., Arendse, L. B., Schwager, S. L., Sturrock, E. D. & Acharya, K-R., 29 Oct 2018, In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

The Design and Development of a Potent and Selective Novel Diprolyl Derivative That Binds to the N-Domain of Angiotensin-I Converting Enzyme

Fienberg, S., Cozier, G. E., Acharya, K. R., Chibale, K. & Sturrock, E. D., 11 Jan 2018, In : Journal of Medicinal Chemistry. 61, 1, p. 344-359 16 p.

Research output: Contribution to journalArticle

Peptidyl-Dipeptidase A
Angioedema
Metalloproteases
Angiotensin-Converting Enzyme Inhibitors
Cough

The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae

Abu Hasan, Z. I., Williams, H., Ismail, N. M., Othman, H., Cozier, G. E., Acharya, K. R. & Isaac, E. R., 27 Mar 2017, In : Scientific Reports. 7, 45409.

Research output: Contribution to journalArticle

Open Access
disease vectors
Anopheles gambiae
peptidyl-dipeptidase A
Aedes aegypti
toxicity