• 10 WEST 3.33

Accepting Doctoral Students

20122020

Research output per year

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Personal profile

Research interests

I investigate the link between DNA methylation and mental health. Specifically, I focus on traits including hyperactivity and behavioural difficulties as well as mental health conditions such as anorexia nervosa and schizophrenia. As an active member of the ENIGMA Schizophrenia and ENIGMA Eating Disorder working groups, I have a long track record of investigating brain imaging correlates of mental health conditions and how these link to genetic and epigenetic markers. In my research I apply several approaches including methylome-wide association analyses, mixed and multi-level modelling, as well as causal inference methods such as Mendelian randomization. I also study the life-course of these associations by applying longitudinal analyses on prospectively collected data from large UK and international cohorts.

 

Biography

I have expert knowledge on mental health research and hands-on experience in leading large-scale collaborations, as part of my work within the ENIGMA consortium. My career has taken me to diverse research environments in the UK (MRC Integrative Epidemiology Unit at the University of Bristol, King’s College London), Germany (TU Dresden), the Netherlands and the US (as part of my DFG-funded postdoctoral fellowship at Georgia State University), allowing me to develop skills, which I apply now in my own research.

 

I use the following methods:

R programming, methylome-wide and genetic association analyses, FreeSurfer, mixed and multi-level modelling, as well as causal inference methods such as Mendelian randomization

Willing to supervise doctoral students

Accepting PhD students

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Projects

EarlyCause

Walton, E.

EU - Horizon 2020

1/01/2031/12/23

Project: EU Commission

Advancing quantification of autistic traits (ESRC SWDTP Studentship)

Walton, E.

1/10/2030/09/24

Project: Research-related funding

Brain ageing in schizophrenia (GW4 BioMed MRC DTP PhD studentship)

Walton, E.

1/10/2030/09/24

Project: Research-related funding

IMI Secondment

Walton, E.

1/10/1931/03/20

Project: Other

CLOSER Innovation Fund

Walton, E.

1/10/1730/09/18

Project: Research-related funding

Research Output

A cross-disorder MR-pheWAS of 5 major psychiatric disorders in UK Biobank

Leppert, B., Millard, L. AC., Riglin, L., Smith, G. D., Thapar, A., Tilling, K., Walton, E. & Stergiakouli, E., 12 Feb 2020, (Acceptance date) In : Plos Genetics.

Research output: Contribution to journalArticle

Open Access

A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank

Leppert, B., Millard, L. A. C., Riglin, L., Davey Smith, G., Thapar, A., Tilling, K., Walton, E. & Stergiakouli, E., 11 May 2020, In : Plos Genetics. 16, 5, p. e1008185

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

ENIGMA Consortium, 20 Mar 2020, In : Translational Psychiatry. 10, 1, 100.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)

Epigenome-wide association study of seizures in childhood and adolescence

Walton, E., Caramaschi, D., Relton, C., Hatcher, C., Felix, J. F., Mulder, R. & Cecil, C. A. M., 8 Jan 2020, In : CLINICAL EPIGENETICS. 12, 1, 8.

Research output: Contribution to journalArticle

Open Access

Epigenomics of being bullied: changes in DNA methylation following bullying exposure

Mulder, R. H., Walton, E., Neumann, A., Houtepen, L. C., Felix, J. F., Bakermans-Kranenburg, M. J., Suderman, M., Tiemeier, H., van IJzendoorn, M. H., Relton, C. L. & Cecil, C. A. M., 28 Jan 2020, In : Epigenetics. p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access