Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
alpha-Synuclein Medicine & Life Sciences
Copper Medicine & Life Sciences
Prion Diseases Medicine & Life Sciences
Prions Chemical Compounds
Metals Medicine & Life Sciences
Manganese Medicine & Life Sciences
beta-Synuclein Medicine & Life Sciences
Neurodegenerative Diseases Medicine & Life Sciences

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Projects 2004 2018

Research Output 2000 2018

File
beta-Synuclein
alpha-Synuclein
Oligomers
Toxicity
Poisons
2 Citations

Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL

McDowall, J. S., Ntai, I., Honeychurch, K. C., Hart, J. P., Colin, P., Schneider, B. L. & Brown, D. 1 Dec 2017 In : Molecular and Cellular Neuroscience. 85, p. 1-11 11 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Parkinson Disease
Dopaminergic Neurons
Substantia Nigra
Dopamine

Metals and Prions: Twenty years of mining the awe

Brown, D. 28 Apr 2017 Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics. White, A. R., Aschner, M., Costa, L. G. & Bush, A. I. (eds.). London, U. K.: Academic Press, p. 95-115

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations

Steady-State Kinetics of α-Synuclein Ferrireductase Activity Identifies the Catalytically Competent Species

McDowall, J. S., Ntai, I., Hake, J., Whitley, P. R., Mason, J. M., Pudney, C. R. & Brown, D. R. 4 May 2017 In : Biochemistry. 56, 19, p. 2497–2505

Research output: Contribution to journalArticle

Open Access
File
alpha-Synuclein
Kinetics
Neurodegenerative diseases
Enzyme activity
Neurodegenerative Diseases
3 Citations

α-Synuclein increases β-amyloid secretion by promoting β-/γ-secretase processing of APP

Roberts, H. L., Schneider, B. L. & Brown, D. R. 1 Feb 2017 In : PLoS ONE. 12, 2, e0171925

Research output: Contribution to journalArticle

Open Access
Amyloid Precursor Protein Secretases
alpha-Synuclein
amyloid
Amyloid
secretion