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Research Output 1991 2019

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Article
2019

An organophosphorus(III)-Selective chemodosimeter for the ratiometric electrochemical detection of phosphines

Spring, S. A., Goggins, S. & Frost, C. G., 11 Apr 2019, In : Chemosensors. 7, 2, 19.

Research output: Contribution to journalArticle

Open Access
2017
1 Citation (Scopus)

A Highly Regioselective Palladium-Catalyzed O,S Rearrangement of Cyclic Thiocarbonates

Mahy, W., Cabezas-Hayes, S., Kociok-Köhn, G. & Frost, C. G., 24 Nov 2017, In : European Journal of Organic Chemistry. 2017, 43, p. 6441-6444 4 p.

Research output: Contribution to journalArticle

Regioselectivity
Palladium
palladium
Crystal structure
Ligands
2 Citations (Scopus)
107 Downloads (Pure)

A peptide nucleic acid (PNA)-DNA ferrocenyl intercalator for electrochemical sensing

Gaiji, H., Jolly, P., Ustuner, S., Goggins, S., Abderrabba, M., Frost, C. & Estrela, P., Mar 2017, In : Electroanalysis. 29, 3, p. 917-922 6 p.

Research output: Contribution to journalArticle

Open Access
File
Intercalating Agents
Peptide Nucleic Acids
DNA
DNA sequences
Biosensors
109 Citations (Scopus)
163 Downloads (Pure)

Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole

Leitch, J. A., Bhonoah, Y. & Frost, C. G., 1 Sep 2017, In : ACS Catalysis. 7, 9, p. 5618-5627 9 p.

Research output: Contribution to journalArticle

Open Access
File
Carbazoles
Agrochemicals
Indoles
Pyrroles
Scaffolds
10 Citations (Scopus)

Ratiometric electrochemical detection of hydrogen peroxide and glucose

Goggins, S., Apsey, E. A., Mahon, M. F. & Frost, C. G., 21 Feb 2017, In : Organic and Biomolecular Chemistry. 15, 11, p. 2459-2466 8 p.

Research output: Contribution to journalArticle

Open Access
Boronic Acids
Enzyme Assays
hydrogen peroxide
glucose
Hydrogen Peroxide
1 Citation (Scopus)
99 Downloads (Pure)

Ratiometric electrochemical detection of Pd•••π interactions: application towards electrochemical molecular logic gates

Goggins, S., Stark, O. P., Naz, C., Marsh, B. J. & Frost, C. G., 2017, In : Supramolecular Chemistry. 29, 10, p. 749-757 9 p.

Research output: Contribution to journalArticle

Open Access
File
Logic gates
Palladium
Roadsides
Health risks
Platinum
3 Citations (Scopus)
75 Downloads (Pure)

Ratiometric electrochemical detection of β-galactosidase

Spring, S. A., Goggins, S. & Frost, C. G., 14 Sep 2017, In : Organic and Biomolecular Chemistry. 15, 34, p. 7122-7126 5 p.

Research output: Contribution to journalArticle

Open Access
File
beta-Galactosidase
Substrates
sensitivity
ferrocene
60 Citations (Scopus)
98 Downloads (Pure)

Remote C6-Selective Ruthenium-Catalyzed C-H Alkylation of Indole Derivatives via σ-Activation

Leitch, J. A., McMullin, C. L., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 7 Apr 2017, In : ACS Catalysis. 7, 4, p. 2616-2623 8 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Alkylation
Catalysis
Chemical activation
Derivatives
26 Citations (Scopus)
28 Downloads (Pure)

Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives

Leitch, J. A., Mcmullin, C. L., Paterson, A. J., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 20 Nov 2017, In : Angewandte Chemie-International Edition. 56, 47, p. 15131-15135 6 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Alkylation
Oxidation-Reduction
aniline
10 Citations (Scopus)
35 Downloads (Pure)

Ruthenium catalyzed remote C4-selective C–H functionalisation of carbazoles via σ-activation

Leitch, J. A., Heron, C. J., Mcknight, J., Kociok-Köhn, G., Bhonoah, Y. & Frost, C. G., 18 Dec 2017, In : Chemical Communications. 4 p.

Research output: Contribution to journalArticle

Open Access
File
Carbazoles
Ruthenium
Chemical activation
Alkylation
Metals
17 Citations (Scopus)

α-Halo carbonyls enable: Meta selective primary, secondary and tertiary C-H alkylations by ruthenium catalysis

Paterson, A. J., Heron, C. J., McMullin, C. L., Mahon, M. F., Press, N. J. & Frost, C. G., 28 Jul 2017, In : Organic and Biomolecular Chemistry. 15, 28, p. 5993-6000 8 p.

Research output: Contribution to journalArticle

Open Access
Ruthenium
alkylation
Alkylation
Catalysis
ruthenium
2016
15 Citations (Scopus)
50 Downloads (Pure)
Open Access
Sewage
Cocaine
Wastewater
DNA
Sensors
7 Citations (Scopus)

Copper catalyzed assembly of N-aryloxazolidinones: synthesis of linezolid, tedizolid, and rivaroxaban

Mahy, W., Leitch, J. A. & Frost, C. G., Mar 2016, In : European Journal of Organic Chemistry. 2016, 7, p. 1305-1313

Research output: Contribution to journalArticle

Linezolid
Copper
assembly
Amino Alcohols
Oxazolidinones
23 Citations (Scopus)

Mechanistic insight into ruthenium catalysed: meta -sulfonation of 2-phenylpyridine

Marcé, P., Paterson, A. J., Mahon, M. F. & Frost, C. G., 7 Oct 2016, In : Catalysis Science and Technology. 6, 19, p. 7068-7076 9 p.

Research output: Contribution to journalArticle

Sulfonation
Ruthenium
Reaction intermediates
Metals
Chemical activation
44 Citations (Scopus)
91 Downloads (Pure)
Open Access
File
Oxazolidinones
Ruthenium
Alkenylation
Isotopes
Kinetics
18 Citations (Scopus)

Use of the hydantoin directing group in ruthenium(II)-catalyzed C-H functionalization

Leitch, J. A., Cook, H. P., Bhonoah, Y. & Frost, C. G., 21 Oct 2016, In : Journal of Organic Chemistry. 81, 20, p. 10081-10087 7 p.

Research output: Contribution to journalArticle

Alkenylation
Hydantoins
Androgen Antagonists
Ruthenium
Application programming interfaces (API)
2015
19 Citations (Scopus)
98 Downloads (Pure)

A novel DNA biosensor using a ferrocenyl intercalator applied to the potential detection of human population biomarkers in wastewater

Yang, Z., Anglès d'Auriac, M., Goggins, S., Kasprzyk-Hordern, B., Thomas, K. V., Frost, C. G. & Estrela, P., 5 May 2015, In : Environmental Science & Technology. 49, 9, p. 5609-5617 9 p.

Research output: Contribution to journalArticle

Open Access
File
Intercalating Agents
Biomarkers
Biosensors
biomarker
Wastewater
41 Citations (Scopus)
81 Downloads (Pure)
File
Nucleotide Aptamers
Prostate-Specific Antigen
Antigens
Tumor Biomarkers
antigen
82 Citations (Scopus)
83 Downloads (Pure)

Catalytic meta-selective C–H functionalization to construct quaternary carbon centres

Paterson, A., St. John-Campbell, S., Mahon, M., Press, N. J. & Frost, C., 18 Aug 2015, In : Chemical Communications. 51, 64, p. 12807-12810 4 p.

Research output: Contribution to journalArticle

Open Access
File
Carbon
Chemical activation
2-phenylpyridine
12 Citations (Scopus)
86 Downloads (Pure)

Community Sewage Sensors for Monitoring Public Health

Yang, Z., Kasprzyk-Hordern, B., Frost, C., Estrela, P. & Thomas, K. V., 19 May 2015, In : Environmental Science & Technology. 49, 10, p. 5845-5846 2 p.

Research output: Contribution to journalArticle

File
71 Citations (Scopus)
133 Downloads (Pure)

Label-Free Impedimetric Aptasensor with Antifouling Surface Chemistry: a Prostate Specific Antigen Case Study

Jolly, P., Formisano, N., Tkac, J., Kasak, P., Frost, C. & Estrela, P., 31 Mar 2015, In : Sensors and Actuators B: Chemical. 209, p. 306-312 7 p.

Research output: Contribution to journalArticle

File
Nucleotide Aptamers
antifouling
Betaines
antigens
Prostate-Specific Antigen

Meet our editorial board member

Frost, C. G., 1 Dec 2015, In : Mini-reviews in Organic Chemistry. 12, 6, p. 465 1 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
107 Downloads (Pure)

Ratiometric electrochemical detection of alkaline phosphatase

Goggins, S., Naz, C., Marsh, B. J. & Frost, C. G., 11 Jan 2015, In : Chemical Communications. 51, 3, p. 561-564 4 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphatases
Alkaline Phosphatase
Immunosorbents
Substrates
Assays
8 Citations (Scopus)
51 Downloads (Pure)

Ruthenium-catalyzed O- to S-alkyl migration: a pseudoreversible Barton-McCombie pathway

Mahy, W., Plucinski, P., Jover, J. & Frost, C. G., 7 Sep 2015, In : Angewandte Chemie-International Edition. 54, 37, p. 10944-10948 5 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Direction compound
9 Citations (Scopus)
88 Downloads (Pure)

Signal transduction and amplification through enzyme-triggered ligand release and accelerated catalysis

Goggins, S., Marsh, B. J., Lubben, A. & Frost, C. G., 1 Aug 2015, In : Chemical Science. 6, 8, p. 4978-4985 8 p.

Research output: Contribution to journalArticle

Open Access
File
Signal transduction
Catalysis
Amplification
Ligands
Catalysts
3 Citations (Scopus)
83 Downloads (Pure)

Trans-selective rhodium catalysed conjugate addition of organoboron reagents to dihydropyranones

Edwards, H. J., Goggins, S. & Frost, C. G., Apr 2015, In : Molecules. 20, 4, p. 6153-6166 14 p.

Research output: Contribution to journalArticle

Open Access
File
Gadiformes
Rhodium
Stereoisomerism
Cycloaddition Reaction
Alkenes
2014
28 Citations (Scopus)
62 Downloads (Pure)

Copper-catalyzed one-pot synthesis of  N-Aryl oxazolidinones from amino alcohol carbamates

Mahy, W., Plucinski, P. K. & Frost, C. G., 2 Oct 2014, In : Organic Letters. 16, 19, p. 5020-5023 4 p.

Research output: Contribution to journalArticle

File
Amino Alcohols
Oxazolidinones
Carbamates
Iodides
iodides
14 Citations (Scopus)
87 Downloads (Pure)

Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

Marsh, B. J., Hampton, L., Goggins, S. & Frost, C. G., 1 Nov 2014, In : New Journal of Chemistry. 38, 11, p. 5260-5263 4 p.

Research output: Contribution to journalArticle

Open Access
File
DNA
Tuning
Derivatives
Hydrophobicity
Chain length
36 Citations (Scopus)

Robust and reusable supported palladium catalysts for cross-coupling reactions in flow

Reynolds, W., Plucinski, P. & Frost, C. G., 1 Apr 2014, In : Catalysis Science and Technology. 4, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Open Access
File
Palladium
Catalysts
Electrons
Silicon Dioxide
Leaching
4 Citations (Scopus)
92 Downloads (Pure)

Silyl-protected dioxaborinanes: Application in the Suzuki cross-coupling reaction

Goggins, S., Rosevere, E., Bellini, C., Allen, J. C., Marsh, B. J., Mahon, M. F. & Frost, C. G., 7 Jan 2014, In : Organic and Biomolecular Chemistry. 12, 1, p. 47-52

Research output: Contribution to journalArticle

File
2013
44 Citations (Scopus)

Ruthenium-catalyzed C-H functionalization of arylpyrazoles: Regioselective acylation with acid chlorides

Liu, P. M. & Frost, C. G., 15 Nov 2013, In : Organic Letters. 15, 22, p. 5862-5865 4 p.

Research output: Contribution to journalArticle

acylation
Acylation
Ruthenium
ruthenium
Chlorides
6 Citations (Scopus)

Synthesis of fluorescent alanines by a rhodium-catalysed conjugate addition of arylboronic acids to dehydroalanine derivatives

Ferreira, P. M. T., Monteiro, L. S., Pereira, G., Castanheira, E. M. S. & Frost, C. G., Jan 2013, In : European Journal of Organic Chemistry. 2013, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

Rhodium
alanine
rhodium
Alanine
Fluorescence
2012
15 Citations (Scopus)
Boronic Acids
Boron
Curcumin
Derivatives
Acids
28 Citations (Scopus)
73 Downloads (Pure)

Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones

Allen, J. C., Kociok-Kohn, G. & Frost, C. G., 2012, In : Organic and Biomolecular Chemistry. 10, 1, p. 32-35 4 p.

Research output: Contribution to journalArticle

Open Access
File
Rhodium
Enantioselectivity
rhodium
reagents
acids
2011
291 Citations (Scopus)
117 Downloads (Pure)

Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines

Saidi, O., Marafie, J., Ledger, A. E. W., Liu, P. M., Mahon, M. F., Kociok-Kohn, G., Whittlesey, M. K. & Frost, C. G., 7 Dec 2011, In : Journal of the American Chemical Society. 133, 48, p. 19298-19301 4 p.

Research output: Contribution to journalArticle

Open Access
File
Sulfonation
Ruthenium
Chelation
Regioselectivity
Sulfones
14 Citations (Scopus)

The effect of reaction conditions on the nature of cadmium 1,3,5-benzenetricarboxylate metal-organic frameworks

Burrows, A. D., Frost, C. G., Kandiah, M., Keenan, L. L., Mahon, M. F., Savarese, T. L. & Warren, J. E., 30 Jan 2011, In : Inorganica Chimica Acta. 366, 1, p. 303-309 7 p.

Research output: Contribution to journalArticle

Pyrazines
Cadmium
cadmium
pyrazines
Metals
2010
47 Citations (Scopus)

Alternatives to organoboron reagents in rhodium-catalyzed conjugate additions

Hargrave, J. D., Allen, J. C. & Frost, C. G., 1 Mar 2010, In : Chemistry - An Asian Journal. 5, 3, p. 386-396 11 p.

Research output: Contribution to journalArticle

Rhodium
Carbon
Organometallics
Addition reactions
Alkenes
18 Citations (Scopus)

A modular approach to catalytic synthesis using a dual-functional linker for Click and Suzuki coupling reactions

White, J. R., Price, G. J., Schiffers, S., Raithby, P. R., Plucinski, P. K. & Frost, C. G., 28 Jul 2010, In : Tetrahedron Letters. 51, 30, p. 3913-3917 5 p.

Research output: Contribution to journalArticle

Alkynes
Azides
Cycloaddition
Cycloaddition Reaction
Esters
13 Citations (Scopus)

Catalytic enantioselective Dieckmann-type annulation: Synthesis of pyrrolidines with quaternary stereogenic centers

Hargrave, J. D., Allen, J. C., Kociok-Kohn, G., Bish, G. & Frost, C. G., 1 Mar 2010, In : Angewandte Chemie-International Edition. 49, 10, p. 1825-1829 5 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Dipyridyl β-diketonate complexes: versatile polydentate metalloligands for metal-organic frameworks and hydrogen-bonded networks

Burrows, A. D., Frost, C. G., Mahon, M. F., Raithby, P. R., Renouf, C. L., Richardson, C. & Stevenson, A., 28 Jul 2010, In : Chemical Communications. 46, 28, p. 5067-5069 3 p.

Research output: Contribution to journalArticle

Europium
Protonation
Coordination Complexes
Metal complexes
Hydrogen
8 Citations (Scopus)

Exploring rhodium-catalysed conjugate addition of chiral alkenylboronates using chiral olefin ligands

Frost, C. G., Edwards, H. J., Penrose, S. D. & Gleave, R., Oct 2010, In : Synthesis. 2010, 19, p. 3243-3247 5 p.

Research output: Contribution to journalArticle

Rhodium
Alkenes
Olefins
Ligands

First catalytic enantioselective Dieckmann-type annulation

Hargrave, J. D., Frost, C. G. & Allen, J. C., Jun 2010, In : Synthesis. 2010, 11, p. A50-A52

Research output: Contribution to journalArticle

213 Citations (Scopus)

Heterogeneous catalytic synthesis using microreactor technology

Frost, C. G. & Mutton, L., Oct 2010, In : Green Chemistry. 12, 10, p. 1687-1703 17 p.

Research output: Contribution to journalArticle

Catalyst supports
catalyst
Catalysts
Ruthenium
Palladium
4 Citations (Scopus)

Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives

Hargrave, J. D., Bish, G., Kociok-Kohn, G. & Frost, C. G., 21 Nov 2010, In : Organic and Biomolecular Chemistry. 8, 22, p. 5120-5125 6 p.

Research output: Contribution to journalArticle

Rhodium
phenylalanine
Protonation
Phenylalanine
rhodium
18 Citations (Scopus)
94 Downloads (Pure)

Solid state interconversion of cages and coordination networks via conformational change of a semi-rigid ligand

Burrows, A. D., Frost, C. G., Mahon, M. F., Raithby, P. R., Richardson, C. & Stevenson, A., 28 Jul 2010, In : Chemical Communications. 46, 28, p. 5064-5066 3 p.

Research output: Contribution to journalArticle

Open Access
File
Ligands
Toluene
Acetonitrile
Silver
Ether
228 Citations (Scopus)

Synthetic applications of rhodium catalysed conjugate addition

Edwards, H. J., Hargrave, J. D., Penrose, S. D. & Frost, C. G., Jun 2010, In : Chemical Society Reviews. 39, 6, p. 2093-2105 13 p.

Research output: Contribution to journalArticle

Rhodium
Carbon
Stereoselectivity
Alkenes
Organometallics
2009
6 Citations (Scopus)

A Practical Synthesis of α-Substituted tert-Butyl Acrylates from Meldrum's Acid and Aldehydes

Frost, C. G., Penrose, S. D. & Gleave, R., 2009, In : Synthesis. 4, p. 627-635 9 p.

Research output: Contribution to journalArticle

Aldehydes
tert-Butyl Alcohol
Acids
Condensation
Alcohols
91 Citations (Scopus)

Easy-separable magnetic nanoparticle-supported Pd catalysts: Kinetics, stability and catalyst re-use

Laska, U., Frost, C. G., Price, G. J. & Plucinski, P. K., 10 Dec 2009, In : Journal of Catalysis. 268, 2, p. 318-328 11 p.

Research output: Contribution to journalArticle

phosphine
reuse
Palladium
Catalyst supports
Hydrogenation
18 Citations (Scopus)
Malonates
Lewis Bases
Hydrosilylation
Aldehydes
Amines
17 Citations (Scopus)

Rhodium-catalyzed 1,4-additions to enantiopure acceptors: asymmetric synthesis of functionalized pyrrolizidinones

Zoute, L., Kociok-Kohn, G. & Frost, C. G., 18 Jun 2009, In : Organic Letters. 11, 12, p. 2491-2494 4 p.

Research output: Contribution to journalArticle

Rhodium
Stereoisomerism
rhodium
Ligands
catalysts