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Research Output 1991 2019

2019

An organophosphorus(III)-Selective chemodosimeter for the ratiometric electrochemical detection of phosphines

Spring, S. A., Goggins, S. & Frost, C. G., 11 Apr 2019, In : Chemosensors. 7, 2, 19.

Research output: Contribution to journalArticle

Open Access
2018
3 Citations (Scopus)
21 Downloads (Pure)

Regioselective Transition-Metal-Catalyzed C–H Functionalization of Anilines

Leitch, J. A. & Frost, C. G., 17 Jul 2018, In : Synthesis (Germany). 50, 14, p. 2693-2706 14 p.

Research output: Contribution to journalReview article

Open Access
File
Aniline Compounds
Aniline
Transition metals
Agrochemicals
Rhodium
2017
1 Citation (Scopus)

A Highly Regioselective Palladium-Catalyzed O,S Rearrangement of Cyclic Thiocarbonates

Mahy, W., Cabezas-Hayes, S., Kociok-Köhn, G. & Frost, C. G., 24 Nov 2017, In : European Journal of Organic Chemistry. 2017, 43, p. 6441-6444 4 p.

Research output: Contribution to journalArticle

Regioselectivity
Palladium
palladium
Crystal structure
Ligands
2 Citations (Scopus)
107 Downloads (Pure)

A peptide nucleic acid (PNA)-DNA ferrocenyl intercalator for electrochemical sensing

Gaiji, H., Jolly, P., Ustuner, S., Goggins, S., Abderrabba, M., Frost, C. & Estrela, P., Mar 2017, In : Electroanalysis. 29, 3, p. 917-922 6 p.

Research output: Contribution to journalArticle

Open Access
File
Intercalating Agents
Peptide Nucleic Acids
DNA
DNA sequences
Biosensors
109 Citations (Scopus)
163 Downloads (Pure)

Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole

Leitch, J. A., Bhonoah, Y. & Frost, C. G., 1 Sep 2017, In : ACS Catalysis. 7, 9, p. 5618-5627 9 p.

Research output: Contribution to journalArticle

Open Access
File
Carbazoles
Agrochemicals
Indoles
Pyrroles
Scaffolds
10 Citations (Scopus)

Ratiometric electrochemical detection of hydrogen peroxide and glucose

Goggins, S., Apsey, E. A., Mahon, M. F. & Frost, C. G., 21 Feb 2017, In : Organic and Biomolecular Chemistry. 15, 11, p. 2459-2466 8 p.

Research output: Contribution to journalArticle

Open Access
Boronic Acids
Enzyme Assays
hydrogen peroxide
glucose
Hydrogen Peroxide
1 Citation (Scopus)
99 Downloads (Pure)

Ratiometric electrochemical detection of Pd•••π interactions: application towards electrochemical molecular logic gates

Goggins, S., Stark, O. P., Naz, C., Marsh, B. J. & Frost, C. G., 2017, In : Supramolecular Chemistry. 29, 10, p. 749-757 9 p.

Research output: Contribution to journalArticle

Open Access
File
Logic gates
Palladium
Roadsides
Health risks
Platinum
3 Citations (Scopus)
75 Downloads (Pure)

Ratiometric electrochemical detection of β-galactosidase

Spring, S. A., Goggins, S. & Frost, C. G., 14 Sep 2017, In : Organic and Biomolecular Chemistry. 15, 34, p. 7122-7126 5 p.

Research output: Contribution to journalArticle

Open Access
File
beta-Galactosidase
Substrates
sensitivity
ferrocene
60 Citations (Scopus)
98 Downloads (Pure)

Remote C6-Selective Ruthenium-Catalyzed C-H Alkylation of Indole Derivatives via σ-Activation

Leitch, J. A., McMullin, C. L., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 7 Apr 2017, In : ACS Catalysis. 7, 4, p. 2616-2623 8 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Alkylation
Catalysis
Chemical activation
Derivatives
26 Citations (Scopus)
28 Downloads (Pure)

Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives

Leitch, J. A., Mcmullin, C. L., Paterson, A. J., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 20 Nov 2017, In : Angewandte Chemie-International Edition. 56, 47, p. 15131-15135 6 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Alkylation
Oxidation-Reduction
aniline
10 Citations (Scopus)
35 Downloads (Pure)

Ruthenium catalyzed remote C4-selective C–H functionalisation of carbazoles via σ-activation

Leitch, J. A., Heron, C. J., Mcknight, J., Kociok-Köhn, G., Bhonoah, Y. & Frost, C. G., 18 Dec 2017, In : Chemical Communications. 4 p.

Research output: Contribution to journalArticle

Open Access
File
Carbazoles
Ruthenium
Chemical activation
Alkylation
Metals
17 Citations (Scopus)

α-Halo carbonyls enable: Meta selective primary, secondary and tertiary C-H alkylations by ruthenium catalysis

Paterson, A. J., Heron, C. J., McMullin, C. L., Mahon, M. F., Press, N. J. & Frost, C. G., 28 Jul 2017, In : Organic and Biomolecular Chemistry. 15, 28, p. 5993-6000 8 p.

Research output: Contribution to journalArticle

Open Access
Ruthenium
alkylation
Alkylation
Catalysis
ruthenium
2016
21 Citations (Scopus)
95 Downloads (Pure)

Approaches towards molecular amplification for sensing

Goggins, S. & Frost, C. G., 7 Jun 2016, In : Analyst. 141, 11, p. 3157-3218 62 p.

Research output: Contribution to journalLiterature review

Open Access
File
Amplification
Limit of Detection
amplification
methodology
Assays
15 Citations (Scopus)
50 Downloads (Pure)
Open Access
Sewage
Cocaine
Wastewater
DNA
Sensors
7 Citations (Scopus)

Copper catalyzed assembly of N-aryloxazolidinones: synthesis of linezolid, tedizolid, and rivaroxaban

Mahy, W., Leitch, J. A. & Frost, C. G., Mar 2016, In : European Journal of Organic Chemistry. 2016, 7, p. 1305-1313

Research output: Contribution to journalArticle

Linezolid
Copper
assembly
Amino Alcohols
Oxazolidinones
23 Citations (Scopus)

Mechanistic insight into ruthenium catalysed: meta -sulfonation of 2-phenylpyridine

Marcé, P., Paterson, A. J., Mahon, M. F. & Frost, C. G., 7 Oct 2016, In : Catalysis Science and Technology. 6, 19, p. 7068-7076 9 p.

Research output: Contribution to journalArticle

Sulfonation
Ruthenium
Reaction intermediates
Metals
Chemical activation
44 Citations (Scopus)
91 Downloads (Pure)
Open Access
File
Oxazolidinones
Ruthenium
Alkenylation
Isotopes
Kinetics
18 Citations (Scopus)

Use of the hydantoin directing group in ruthenium(II)-catalyzed C-H functionalization

Leitch, J. A., Cook, H. P., Bhonoah, Y. & Frost, C. G., 21 Oct 2016, In : Journal of Organic Chemistry. 81, 20, p. 10081-10087 7 p.

Research output: Contribution to journalArticle

Alkenylation
Hydantoins
Androgen Antagonists
Ruthenium
Application programming interfaces (API)
2015
19 Citations (Scopus)
98 Downloads (Pure)

A novel DNA biosensor using a ferrocenyl intercalator applied to the potential detection of human population biomarkers in wastewater

Yang, Z., Anglès d'Auriac, M., Goggins, S., Kasprzyk-Hordern, B., Thomas, K. V., Frost, C. G. & Estrela, P., 5 May 2015, In : Environmental Science & Technology. 49, 9, p. 5609-5617 9 p.

Research output: Contribution to journalArticle

Open Access
File
Intercalating Agents
Biomarkers
Biosensors
biomarker
Wastewater
41 Citations (Scopus)
80 Downloads (Pure)
File
Nucleotide Aptamers
Prostate-Specific Antigen
Antigens
Tumor Biomarkers
antigen
82 Citations (Scopus)
83 Downloads (Pure)

Catalytic meta-selective C–H functionalization to construct quaternary carbon centres

Paterson, A., St. John-Campbell, S., Mahon, M., Press, N. J. & Frost, C., 18 Aug 2015, In : Chemical Communications. 51, 64, p. 12807-12810 4 p.

Research output: Contribution to journalArticle

Open Access
File
Carbon
Chemical activation
2-phenylpyridine

Community Sensors for Monitoring of Public Health by Means of Wastewater-Based Epidemiology

Yang, Z., Kasprzyk-Hordern, B., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Thomas, K. V., Frost, C. & Estrela, P., 11 Oct 2015, (Unpublished).

Research output: Contribution to conferencePoster

Community Sensors for Monitoring Public Health using Wastewater-Based Epidemiology

Yang, Z., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Estrela, P., Frost, C., Thomas, K. V. & Kasprzyk-Hordern, B., 20 Sep 2015, (Unpublished).

Research output: Contribution to conferencePoster

12 Citations (Scopus)
86 Downloads (Pure)

Community Sewage Sensors for Monitoring Public Health

Yang, Z., Kasprzyk-Hordern, B., Frost, C., Estrela, P. & Thomas, K. V., 19 May 2015, In : Environmental Science & Technology. 49, 10, p. 5845-5846 2 p.

Research output: Contribution to journalArticle

File

Electrochemical Community Sensors for Monitoring of Public Health at Population Level Using Wastewater-Based Epidemiology

Yang, Z., Kasprzyk-Hordern, B., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Thomas, K. V., Frost, C. & Estrela, P., 13 Aug 2015, (Unpublished).

Research output: Contribution to conferencePaper

71 Citations (Scopus)
132 Downloads (Pure)

Label-Free Impedimetric Aptasensor with Antifouling Surface Chemistry: a Prostate Specific Antigen Case Study

Jolly, P., Formisano, N., Tkac, J., Kasak, P., Frost, C. & Estrela, P., 31 Mar 2015, In : Sensors and Actuators B: Chemical. 209, p. 306-312 7 p.

Research output: Contribution to journalArticle

File
Nucleotide Aptamers
antifouling
Betaines
antigens
Prostate-Specific Antigen

Meet our editorial board member

Frost, C. G., 1 Dec 2015, In : Mini-reviews in Organic Chemistry. 12, 6, p. 465 1 p.

Research output: Contribution to journalArticle

72 Citations (Scopus)
107 Downloads (Pure)

Ratiometric electrochemical detection of alkaline phosphatase

Goggins, S., Naz, C., Marsh, B. J. & Frost, C. G., 11 Jan 2015, In : Chemical Communications. 51, 3, p. 561-564 4 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphatases
Alkaline Phosphatase
Immunosorbents
Substrates
Assays
6 Citations (Scopus)

Recent Developments in Selective C-H Functionalisation

Frost, C. G., Marce, P. & Liu, P. M., Oct 2015, Organometallic Chemistry. Fairlamb, I. J. S. & Lynam, J. (eds.). Abingdon, U. K.: Royal Society of Chemistry, p. 54-87 34 p. (Organometallic Chemistry; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingChapter

Carbon
Catalysis
8 Citations (Scopus)
51 Downloads (Pure)

Ruthenium-catalyzed O- to S-alkyl migration: a pseudoreversible Barton-McCombie pathway

Mahy, W., Plucinski, P., Jover, J. & Frost, C. G., 7 Sep 2015, In : Angewandte Chemie-International Edition. 54, 37, p. 10944-10948 5 p.

Research output: Contribution to journalArticle

Open Access
File
Ruthenium
Direction compound

Sewage Biosensor to Identify Potential Population Biomarker for Monitoring of Public Health

Yang, Z., Anglès d’Auriac, M., Goggins, S., Kasprzyk-Hordern, B., Thomas, K. V., Frost, C. & Estrela, P., 16 Jun 2015, (Unpublished).

Research output: Contribution to conferencePoster

Biomarkers
Public health
Sewage
Mitochondrial DNA
Biosensors
9 Citations (Scopus)
88 Downloads (Pure)

Signal transduction and amplification through enzyme-triggered ligand release and accelerated catalysis

Goggins, S., Marsh, B. J., Lubben, A. & Frost, C. G., 1 Aug 2015, In : Chemical Science. 6, 8, p. 4978-4985 8 p.

Research output: Contribution to journalArticle

Open Access
File
Signal transduction
Catalysis
Amplification
Ligands
Catalysts
3 Citations (Scopus)
83 Downloads (Pure)

Trans-selective rhodium catalysed conjugate addition of organoboron reagents to dihydropyranones

Edwards, H. J., Goggins, S. & Frost, C. G., Apr 2015, In : Molecules. 20, 4, p. 6153-6166 14 p.

Research output: Contribution to journalArticle

Open Access
File
Gadiformes
Rhodium
Stereoisomerism
Cycloaddition Reaction
Alkenes
2014

A novel method of aptamer immobilization for sensitive cancer biomarker detection

Yang, Z., Jolly, P., Goggins, S., Kasprzyk-Hordern, B., Frost, C. G. & Estrela, P., 2014, (Unpublished).

Research output: Contribution to conferencePoster

28 Citations (Scopus)
62 Downloads (Pure)

Copper-catalyzed one-pot synthesis of  N-Aryl oxazolidinones from amino alcohol carbamates

Mahy, W., Plucinski, P. K. & Frost, C. G., 2 Oct 2014, In : Organic Letters. 16, 19, p. 5020-5023 4 p.

Research output: Contribution to journalArticle

File
Amino Alcohols
Oxazolidinones
Carbamates
Iodides
iodides

Elaboration of Biosensors with Self-Assembled Monolayer and Polymer Layer for Cancer Diagnosis

Yang, Z., Kasprzyk-Hordern, B., Estrela, P. & Frost, C., 16 Sep 2014, (Unpublished).

Research output: Contribution to conferencePoster

14 Citations (Scopus)
86 Downloads (Pure)

Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

Marsh, B. J., Hampton, L., Goggins, S. & Frost, C. G., 1 Nov 2014, In : New Journal of Chemistry. 38, 11, p. 5260-5263 4 p.

Research output: Contribution to journalArticle

Open Access
File
DNA
Tuning
Derivatives
Hydrophobicity
Chain length
36 Citations (Scopus)

Robust and reusable supported palladium catalysts for cross-coupling reactions in flow

Reynolds, W., Plucinski, P. & Frost, C. G., 1 Apr 2014, In : Catalysis Science and Technology. 4, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Open Access
File
Palladium
Catalysts
Electrons
Silicon Dioxide
Leaching
4 Citations (Scopus)
92 Downloads (Pure)

Silyl-protected dioxaborinanes: Application in the Suzuki cross-coupling reaction

Goggins, S., Rosevere, E., Bellini, C., Allen, J. C., Marsh, B. J., Mahon, M. F. & Frost, C. G., 7 Jan 2014, In : Organic and Biomolecular Chemistry. 12, 1, p. 47-52

Research output: Contribution to journalArticle

File
2013
6 Citations (Scopus)

Coupling Reactions in Continuous-Flow Systems

Reynolds, W. & Frost, C., 2 Apr 2013, Palladium-Catalysed Coupling Reactions: Practical Aspects and Future Developments. Molnar, A. (ed.). Weinheim: Wiley-VCH, p. 409-440 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

44 Citations (Scopus)

Ruthenium-catalyzed C-H functionalization of arylpyrazoles: Regioselective acylation with acid chlorides

Liu, P. M. & Frost, C. G., 15 Nov 2013, In : Organic Letters. 15, 22, p. 5862-5865 4 p.

Research output: Contribution to journalArticle

acylation
Acylation
Ruthenium
ruthenium
Chlorides
24 Citations (Scopus)

Sequential chelation-assisted aromatic C–H functionalisation via catalytic meta sulfonation

Reynolds, W. R., Liu, P. M., Kociok-Kohn, G. & Frost, C. G., 17 Dec 2013, In : Synlett. 24, 20, p. 2687-2690 4 p., ST-2013-D0836-L.

Research output: Contribution to journalLetter

Regioselectivity
Sulfonation
Chelation
Reaction products
2-phenylpyridine
6 Citations (Scopus)

Synthesis of fluorescent alanines by a rhodium-catalysed conjugate addition of arylboronic acids to dehydroalanine derivatives

Ferreira, P. M. T., Monteiro, L. S., Pereira, G., Castanheira, E. M. S. & Frost, C. G., Jan 2013, In : European Journal of Organic Chemistry. 2013, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

Rhodium
alanine
rhodium
Alanine
Fluorescence
2012
15 Citations (Scopus)
Boronic Acids
Boron
Curcumin
Derivatives
Acids

Novel Ferrocene Labels For Electrochemical Assay and Their Use in Analytical Methods

Flower, S., Frost, C., Marsh, B. & Sharp, J., 28 Jun 2012, IPC No. C07F 17/02(2006.01), Patent No. WO 2012/085591 A1

Research output: Patent

Labels
Assays
Substrates
Carbon Monoxide
Hydrogen
28 Citations (Scopus)
73 Downloads (Pure)

Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones

Allen, J. C., Kociok-Kohn, G. & Frost, C. G., 2012, In : Organic and Biomolecular Chemistry. 10, 1, p. 32-35 4 p.

Research output: Contribution to journalArticle

Open Access
File
Rhodium
Enantioselectivity
rhodium
reagents
acids
2011
291 Citations (Scopus)
117 Downloads (Pure)

Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines

Saidi, O., Marafie, J., Ledger, A. E. W., Liu, P. M., Mahon, M. F., Kociok-Kohn, G., Whittlesey, M. K. & Frost, C. G., 7 Dec 2011, In : Journal of the American Chemical Society. 133, 48, p. 19298-19301 4 p.

Research output: Contribution to journalArticle

Open Access
File
Sulfonation
Ruthenium
Chelation
Regioselectivity
Sulfones
14 Citations (Scopus)

The effect of reaction conditions on the nature of cadmium 1,3,5-benzenetricarboxylate metal-organic frameworks

Burrows, A. D., Frost, C. G., Kandiah, M., Keenan, L. L., Mahon, M. F., Savarese, T. L. & Warren, J. E., 30 Jan 2011, In : Inorganica Chimica Acta. 366, 1, p. 303-309 7 p.

Research output: Contribution to journalArticle

Pyrazines
Cadmium
cadmium
pyrazines
Metals