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Research Output

2019

An organophosphorus(III)-Selective chemodosimeter for the ratiometric electrochemical detection of phosphines

Spring, S. A., Goggins, S. & Frost, C. G., 11 Apr 2019, In : Chemosensors. 7, 2, 19.

Research output: Contribution to journalArticle

Open Access
2018

Regioselective Transition-Metal-Catalyzed C–H Functionalization of Anilines

Leitch, J. A. & Frost, C. G., 17 Jul 2018, In : Synthesis (Germany). 50, 14, p. 2693-2706 14 p.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
46 Downloads (Pure)
2017

A Highly Regioselective Palladium-Catalyzed O,S Rearrangement of Cyclic Thiocarbonates

Mahy, W., Cabezas-Hayes, S., Kociok-Köhn, G. & Frost, C. G., 24 Nov 2017, In : European Journal of Organic Chemistry. 2017, 43, p. 6441-6444 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A peptide nucleic acid (PNA)-DNA ferrocenyl intercalator for electrochemical sensing

Gaiji, H., Jolly, P., Ustuner, S., Goggins, S., Abderrabba, M., Frost, C. & Estrela, P., Mar 2017, In : Electroanalysis. 29, 3, p. 917-922 6 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
147 Downloads (Pure)

Beyond C2 and C3: Transition-Metal-Catalyzed C–H Functionalization of Indole

Leitch, J. A., Bhonoah, Y. & Frost, C. G., 1 Sep 2017, In : ACS Catalysis. 7, 9, p. 5618-5627 9 p.

Research output: Contribution to journalArticle

Open Access
File
130 Citations (Scopus)
218 Downloads (Pure)

Ratiometric electrochemical detection of hydrogen peroxide and glucose

Goggins, S., Apsey, E. A., Mahon, M. F. & Frost, C. G., 21 Feb 2017, In : Organic and Biomolecular Chemistry. 15, 11, p. 2459-2466 8 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Ratiometric electrochemical detection of Pd•••π interactions: application towards electrochemical molecular logic gates

Goggins, S., Stark, O. P., Naz, C., Marsh, B. J. & Frost, C. G., 2017, In : Supramolecular Chemistry. 29, 10, p. 749-757 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
133 Downloads (Pure)

Ratiometric electrochemical detection of β-galactosidase

Spring, S. A., Goggins, S. & Frost, C. G., 14 Sep 2017, In : Organic and Biomolecular Chemistry. 15, 34, p. 7122-7126 5 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
111 Downloads (Pure)

Remote C6-Selective Ruthenium-Catalyzed C-H Alkylation of Indole Derivatives via σ-Activation

Leitch, J. A., McMullin, C. L., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 7 Apr 2017, In : ACS Catalysis. 7, 4, p. 2616-2623 8 p.

Research output: Contribution to journalArticle

Open Access
File
64 Citations (Scopus)
147 Downloads (Pure)

Ruthenium-Catalyzed para-Selective C−H Alkylation of Aniline Derivatives

Leitch, J. A., Mcmullin, C. L., Paterson, A. J., Mahon, M. F., Bhonoah, Y. & Frost, C. G., 20 Nov 2017, In : Angewandte Chemie-International Edition. 56, 47, p. 15131-15135 6 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
45 Downloads (Pure)

Ruthenium catalyzed remote C4-selective C–H functionalisation of carbazoles via σ-activation

Leitch, J. A., Heron, C. J., Mcknight, J., Kociok-Köhn, G., Bhonoah, Y. & Frost, C. G., 18 Dec 2017, In : Chemical Communications. 4 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
48 Downloads (Pure)

α-Halo carbonyls enable: Meta selective primary, secondary and tertiary C-H alkylations by ruthenium catalysis

Paterson, A. J., Heron, C. J., McMullin, C. L., Mahon, M. F., Press, N. J. & Frost, C. G., 28 Jul 2017, In : Organic and Biomolecular Chemistry. 15, 28, p. 5993-6000 8 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2016

Approaches towards molecular amplification for sensing

Goggins, S. & Frost, C. G., 7 Jun 2016, In : Analyst. 141, 11, p. 3157-3218 62 p.

Research output: Contribution to journalLiterature review

Open Access
File
24 Citations (Scopus)
146 Downloads (Pure)
Open Access
20 Citations (Scopus)
50 Downloads (Pure)

Copper catalyzed assembly of N-aryloxazolidinones: synthesis of linezolid, tedizolid, and rivaroxaban

Mahy, W., Leitch, J. A. & Frost, C. G., Mar 2016, In : European Journal of Organic Chemistry. 2016, 7, p. 1305-1313

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mechanistic insight into ruthenium catalysed: meta -sulfonation of 2-phenylpyridine

Marcé, P., Paterson, A. J., Mahon, M. F. & Frost, C. G., 7 Oct 2016, In : Catalysis Science and Technology. 6, 19, p. 7068-7076 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
Open Access
File
50 Citations (Scopus)
136 Downloads (Pure)

Use of the hydantoin directing group in ruthenium(II)-catalyzed C-H functionalization

Leitch, J. A., Cook, H. P., Bhonoah, Y. & Frost, C. G., 21 Oct 2016, In : Journal of Organic Chemistry. 81, 20, p. 10081-10087 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2015

A novel DNA biosensor using a ferrocenyl intercalator applied to the potential detection of human population biomarkers in wastewater

Yang, Z., Anglès d'Auriac, M., Goggins, S., Kasprzyk-Hordern, B., Thomas, K. V., Frost, C. G. & Estrela, P., 5 May 2015, In : Environmental Science & Technology. 49, 9, p. 5609-5617 9 p.

Research output: Contribution to journalArticle

Open Access
File
23 Citations (Scopus)
153 Downloads (Pure)
File
43 Citations (Scopus)
108 Downloads (Pure)

Catalytic meta-selective C–H functionalization to construct quaternary carbon centres

Paterson, A., St. John-Campbell, S., Mahon, M., Press, N. J. & Frost, C., 18 Aug 2015, In : Chemical Communications. 51, 64, p. 12807-12810 4 p.

Research output: Contribution to journalArticle

Open Access
File
87 Citations (Scopus)
118 Downloads (Pure)

Community Sensors for Monitoring of Public Health by Means of Wastewater-Based Epidemiology

Yang, Z., Kasprzyk-Hordern, B., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Thomas, K. V., Frost, C. & Estrela, P., 11 Oct 2015, (Unpublished).

Research output: Contribution to conferencePoster

Community Sensors for Monitoring Public Health using Wastewater-Based Epidemiology

Yang, Z., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Estrela, P., Frost, C., Thomas, K. V. & Kasprzyk-Hordern, B., 20 Sep 2015, (Unpublished).

Research output: Contribution to conferencePoster

Community Sewage Sensors for Monitoring Public Health

Yang, Z., Kasprzyk-Hordern, B., Frost, C., Estrela, P. & Thomas, K. V., 19 May 2015, In : Environmental Science & Technology. 49, 10, p. 5845-5846 2 p.

Research output: Contribution to journalArticle

File
16 Citations (Scopus)
142 Downloads (Pure)

Electrochemical Community Sensors for Monitoring of Public Health at Population Level Using Wastewater-Based Epidemiology

Yang, Z., Kasprzyk-Hordern, B., Anglès d’Auriac, M., Goggins, S., Castrignano, E., Rice, J., Thomas, K. V., Frost, C. & Estrela, P., 13 Aug 2015, (Unpublished).

Research output: Contribution to conferencePaper

Label-Free Impedimetric Aptasensor with Antifouling Surface Chemistry: a Prostate Specific Antigen Case Study

Jolly, P., Formisano, N., Tkac, J., Kasak, P., Frost, C. & Estrela, P., 31 Mar 2015, In : Sensors and Actuators B: Chemical. 209, p. 306-312 7 p.

Research output: Contribution to journalArticle

File
82 Citations (Scopus)
192 Downloads (Pure)

Meet our editorial board member

Frost, C. G., 1 Dec 2015, In : Mini-reviews in Organic Chemistry. 12, 6, p. 465 1 p.

Research output: Contribution to journalArticle

Ratiometric electrochemical detection of alkaline phosphatase

Goggins, S., Naz, C., Marsh, B. J. & Frost, C. G., 11 Jan 2015, In : Chemical Communications. 51, 3, p. 561-564 4 p.

Research output: Contribution to journalArticle

Open Access
File
82 Citations (Scopus)
153 Downloads (Pure)

Recent Developments in Selective C-H Functionalisation

Frost, C. G., Marce, P. & Liu, P. M., Oct 2015, Organometallic Chemistry. Fairlamb, I. J. S. & Lynam, J. (eds.). Abingdon, U. K.: Royal Society of Chemistry, p. 54-87 34 p. (Organometallic Chemistry; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Ruthenium-catalyzed O- to S-alkyl migration: a pseudoreversible Barton-McCombie pathway

Mahy, W., Plucinski, P., Jover, J. & Frost, C. G., 7 Sep 2015, In : Angewandte Chemie-International Edition. 54, 37, p. 10944-10948 5 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
87 Downloads (Pure)

Sewage Biosensor to Identify Potential Population Biomarker for Monitoring of Public Health

Yang, Z., Anglès d’Auriac, M., Goggins, S., Kasprzyk-Hordern, B., Thomas, K. V., Frost, C. & Estrela, P., 16 Jun 2015, (Unpublished).

Research output: Contribution to conferencePoster

Signal transduction and amplification through enzyme-triggered ligand release and accelerated catalysis

Goggins, S., Marsh, B. J., Lubben, A. & Frost, C. G., 1 Aug 2015, In : Chemical Science. 6, 8, p. 4978-4985 8 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
122 Downloads (Pure)

Trans-selective rhodium catalysed conjugate addition of organoboron reagents to dihydropyranones

Edwards, H. J., Goggins, S. & Frost, C. G., Apr 2015, In : Molecules. 20, 4, p. 6153-6166 14 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
118 Downloads (Pure)
2014

A novel method of aptamer immobilization for sensitive cancer biomarker detection

Yang, Z., Jolly, P., Goggins, S., Kasprzyk-Hordern, B., Frost, C. G. & Estrela, P., 2014, (Unpublished).

Research output: Contribution to conferencePoster

Copper-catalyzed one-pot synthesis of  N-Aryl oxazolidinones from amino alcohol carbamates

Mahy, W., Plucinski, P. K. & Frost, C. G., 2 Oct 2014, In : Organic Letters. 16, 19, p. 5020-5023 4 p.

Research output: Contribution to journalArticle

File
28 Citations (Scopus)
99 Downloads (Pure)

Elaboration of Biosensors with Self-Assembled Monolayer and Polymer Layer for Cancer Diagnosis

Yang, Z., Kasprzyk-Hordern, B., Estrela, P. & Frost, C., 16 Sep 2014, (Unpublished).

Research output: Contribution to conferencePoster

Fine-tuning of ferrocene redox potentials towards multiplex DNA detection

Marsh, B. J., Hampton, L., Goggins, S. & Frost, C. G., 1 Nov 2014, In : New Journal of Chemistry. 38, 11, p. 5260-5263 4 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
131 Downloads (Pure)

Robust and reusable supported palladium catalysts for cross-coupling reactions in flow

Reynolds, W., Plucinski, P. & Frost, C. G., 1 Apr 2014, In : Catalysis Science and Technology. 4, 4, p. 948-954 7 p.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
8 Downloads (Pure)

Silyl-protected dioxaborinanes: Application in the Suzuki cross-coupling reaction

Goggins, S., Rosevere, E., Bellini, C., Allen, J. C., Marsh, B. J., Mahon, M. F. & Frost, C. G., 7 Jan 2014, In : Organic and Biomolecular Chemistry. 12, 1, p. 47-52

Research output: Contribution to journalArticle

File
4 Citations (Scopus)
133 Downloads (Pure)
2013

Coupling Reactions in Continuous-Flow Systems

Reynolds, W. & Frost, C., 2 Apr 2013, Palladium-Catalysed Coupling Reactions: Practical Aspects and Future Developments. Molnar, A. (ed.). Weinheim: Wiley-VCH, p. 409-440 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Citations (Scopus)

Ruthenium-catalyzed C-H functionalization of arylpyrazoles: Regioselective acylation with acid chlorides

Liu, P. M. & Frost, C. G., 15 Nov 2013, In : Organic Letters. 15, 22, p. 5862-5865 4 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Sequential chelation-assisted aromatic C–H functionalisation via catalytic meta sulfonation

Reynolds, W. R., Liu, P. M., Kociok-Kohn, G. & Frost, C. G., 17 Dec 2013, In : Synlett. 24, 20, p. 2687-2690 4 p., ST-2013-D0836-L.

Research output: Contribution to journalLetter

24 Citations (Scopus)

Synthesis of fluorescent alanines by a rhodium-catalysed conjugate addition of arylboronic acids to dehydroalanine derivatives

Ferreira, P. M. T., Monteiro, L. S., Pereira, G., Castanheira, E. M. S. & Frost, C. G., Jan 2013, In : European Journal of Organic Chemistry. 2013, 3, p. 550-556 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2012

A simple and effective colorimetric technique for the detection of boronic acids and their derivatives

Lawrence, K., Flower, S. E., Kociok-Kohn, G., Frost, C. G. & James, T. D., 2012, In : Analytical Methods. 4, 8, p. 2215-2217 3 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Novel Ferrocene Labels For Electrochemical Assay and Their Use in Analytical Methods

Flower, S., Frost, C., Marsh, B. & Sharp, J., 28 Jun 2012, IPC No. C07F 17/02(2006.01), Patent No. WO 2012/085591 A1

Research output: Patent

Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones

Allen, J. C., Kociok-Kohn, G. & Frost, C. G., 2012, In : Organic and Biomolecular Chemistry. 10, 1, p. 32-35 4 p.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
106 Downloads (Pure)
2011

Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines

Saidi, O., Marafie, J., Ledger, A. E. W., Liu, P. M., Mahon, M. F., Kociok-Kohn, G., Whittlesey, M. K. & Frost, C. G., 7 Dec 2011, In : Journal of the American Chemical Society. 133, 48, p. 19298-19301 4 p.

Research output: Contribution to journalArticle

Open Access
File
309 Citations (Scopus)
174 Downloads (Pure)