• 5 WEST 2.49C

Accepting PhD Students

19982021

Research output per year

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Research Output

Agonist-selective mechanisms of GPCR desensitization

Kelly, E., Bailey, C. P. & Henderson, G., 2008, In : British Journal of Pharmacology. 153, S1, p. S379-S388

Research output: Contribution to journalArticle

254 Citations (Scopus)

Agonist-selective mechanisms of μ-opioid receptor desensitization in human embryonic kidney 293 cells

Johnson, E. A., Oldfield, S., Braksator, E., Gonzalez-Cuello, A., Couch, D., Hall, K. J., Mundell, S. J., Bailey, C. P., Kelly, E. & Henderson, G., 2006, In : Molecular Pharmacology. 70, 2, p. 676-685 10 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption

Bailey, C. P., O'Callaghan, M. J., Croft, A. P., Manley, S. J. & Little, H. J., 2001, In : Neuropharmacology. 41, p. 989-999 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)
Open Access
File
29 Citations (Scopus)
187 Downloads (Pure)

A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain

Conibear, A. E., Asghar, J., Hill, R., Henderson, G., Borbely, E., Tekus, V., Helyes, Z., Palandri, J., Bailey, C. P., Starke, I., von Mentzer, B., Kendall, D. & Kelly, E., 8 Oct 2019, In : Journal of Pharmacology and Experimental Therapeutics.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Antidepressant-like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice

Almatroudi, A. M. I., Ostovar, M., Bailey, C., Husbands, S. & Bailey, S., 1 Jul 2018, In : British Journal of Pharmacology. 175, 14, p. 2869-2880 12 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
48 Downloads (Pure)

Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability

Bailey, C. P., Manley, S. J., Watson, W. P., Wonnacott, S., Molleman, A. & Little, H. J., 24 Aug 1998, In : Brain Research. 803, 1-2, p. 144-152 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice

Almatroudi, A., Husbands, S. M., Bailey, C. P. & Bailey, S. J., 1 Jul 2015, In : Journal of Psychopharmacology . 29, 7, p. 812-821 10 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
131 Downloads (Pure)

Comparison of the effects of drugs on hyperexcitability induced in hippocampal slices by withdrawal from chronic ethanol consumption

Bailey, C. P., Molleman, A. & Little, H. J., 28 Jan 1998, In : British Journal of Pharmacology. 123, 2, p. 215-222 8 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

C-terminal splice variants of the μ-opioid receptor: existence, distribution and functional characteristics

Oldfield, S., Braksator, E., Rodriguez-Martin, I., Bailey, C. P., Donaldson, L. F., Henderson, G. & Kelly, E., 2008, In : Journal of Neurochemistry. 104, 4, p. 937-945 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Does alcohol increase the risk of overdose death: the need for a translational approach

Hickman, M., Lingford-Hughes, A., Bailey, C., Macleod, J., Nutt, D. & Henderson, G., 2008, In : Addiction. 103, 7, p. 1060-1062 3 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Elucidating agonist-selective mechanisms of G protein-coupled receptor desensitization

Bailey, C. P. & Kelly, E., 4 Aug 2011, Methods for the Discovery and Characterization of G Protein-Coupled Receptors. Stevens, C. W. (ed.). Humana Press, p. 323-346 24 p. (Neuromethods; vol. 60).

Research output: Chapter in Book/Report/Conference proceedingChapter

Emerging areas of opioid pharmacology

Kelly, E., Henderson, G. & Bailey, C. P., 1 Jul 2018, In : British Journal of Pharmacology. 175, 14, p. 2715-2716 2 p.

Research output: Contribution to journalEditorial

File
170 Downloads (Pure)

Endomorphin-2: A biased agonist at the μ-opioid receptor

Rivero, G., Llorente, J., McPherson, J., Cooke, A., Mundell, S. J., McArdle, C. A., Rosethorne, E. M., Charlton, S. J., Krasel, C., Bailey, C. P., Henderson, G. & Kelly, E., 2012, In : Molecular Pharmacology. 82, 2, p. 178-188 11 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons

Llorente, J., Withey, S., Rivero, G., Cunningham, M., Cooke, A., Saxena, K., McPherson, J., Oldfield, S., Dewey, W. L., Bailey, C. P., Kelly, E. & Henderson, G., Aug 2013, In : Molecular Pharmacology. 84, 2, p. 252-260 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Ethanol reversal of tolerance to the respiratory depressant effects of morphine

Hill, R., Lyndon, A., Withey, S., Roberts, J., Kershaw, Y., MacLachlan, J., Lingford-Hughes, A., Kelly, E., Bailey, C., Hickman, M. & Henderson, G., 1 Feb 2016, In : Neuropsychopharmacology. 41, 3, p. 762-773 12 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
42 Downloads (Pure)

Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance

Gabra, B. H., Bailey, C. P., Kelly, E., Sanders, A. V., Henderson, G., Smith, F. L. & Dewey, W. L., 2007, In : Brain Research. 1159, p. 86-93 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
Open Access
12 Citations (Scopus)

Functional selectivity in GPCR desensitization

Bailey, C., Henderson, G. & Kelly, E., 2008, In : Fundamental & Clinical Pharmacology. 22, p. 7-7 1 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

i2 inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses

Bailey, C. P., Nicholls, R. E., Zhang, X. L., Zhou, Z. Y., Muller, W., Kandel, E. R. & Stanton, P. K., 2008, In : Learning and Memory. 15, 4, p. 261-270 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance?

Bailey, C. P., Smith, F. L., Kelly, E., Dewey, W. L. & Henderson, G., 2006, In : Trends in Pharmacological Sciences. 27, 11, p. 558-565 8 p.

Research output: Contribution to journalArticle

70 Citations (Scopus)
Open Access
3 Citations (Scopus)
21 Downloads (Pure)
Open Access
7 Citations (Scopus)
86 Downloads (Pure)

Investigating the effects of gender on anxiety related behaviour evoked by kappa opioid receptor activation in the elevated plus maze

Lalji, H., Almatroudi, A. M. I., Bailey, C. & Bailey, S., 1 Aug 2017, (Accepted/In press) In : Journal of Psychopharmacology . 31, 8, p. A21

Research output: Contribution to journalMeeting abstract

File
30 Downloads (Pure)

Involvement of PKCα and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of µ-opioid receptors in mature brain neurons

Bailey, C. P., Oldfield, S., Llorente, J., Caunt, C. J., Teschemacher, AG., Roberts, L., McArdle, CA., Smith, FL., Dewey, WL., Kelly, E. & Henderson, G., Sep 2009, In : British Journal of Pharmacology. 158, 1, p. 157-164 8 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Lack of agonist-induced desensitization of mu-opioid receptors located at nerve terminals

Lowe, J. D. & Bailey, C. P., 2011, In : Pharmacological Reports. 63, 1, p. 235 1 p.

Research output: Contribution to journalArticle

Long-term depression of presynaptic release from the readily releasable vesicle pool induced by NMDA receptor-dependent retrograde nitric oxide

Stanton, P. K., Winterer, J., Bailey, C. P., Kyrozis, A., Raginov, I., Laube, G., Veh, R. W., Nguyen, C. Q. & Müller, W., 2003, In : Journal of Neuroscience. 23, 13, p. 5936-5944 9 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Methadone: Does it really have low efficacy at mu-opioid receptors?

Rodriguez-Martin, I., Braksator, E., Bailey, C. P., Goodchild, S., Marrion, N. V., Kelly, E. & Henderson, G., Mar 2008, In : Neuroreport. 19, 5, p. 589-593 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

MGluR2 acts through inhibitory Gα subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses

Nicholls, R. E., Zhang, X. L., Bailey, C. P., Conklin, B. R., Kandel, E. R. & Stanton, P. K., 2006, In : Proceedings of the National Academy of Sciences of the United States of America (PNAS). 103, 16, p. 6380-6385 6 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Morphine-induced respiratory depression is independent of β-arrestin2 signalling

Kliewer, A., Gillis, A., Hill, R., Schmidel, F., Bailey, C., Kelly, E., Henderson, G., Christie, M. J. & Schulz, S., 12 Feb 2020, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Morphine tolerance: getting hooked

Bailey, C. P., 2007, In : The Biochemist. 29, p. 12-15 4 p.

Research output: Contribution to journalArticle

Mu-opioid receptor internalisation: Studies using a pHluorin tag

Baptist, M., Braksator, E., Bailey, C., Kelly, E. & Henderson, G., 2008, In : Fundamental & Clinical Pharmacology. 22, p. 60-60 1 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)
Open Access
File
13 Citations (Scopus)
70 Downloads (Pure)

Opioids: cellular mechanisms of tolerance and physical dependence

Bailey, C. P. & Connor, M., 2005, In : Current Opinion in Pharmacology. 5, 1, p. 60-68 9 p.

Research output: Contribution to journalArticle

203 Citations (Scopus)
16 Citations (Scopus)

Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice

Gabra, B. H., Bailey, C. P., Kelly, E., Smith, F. L., Henderson, G. & Dewey, W. L., 27 Jun 2008, In : Brain Research. 1217, p. 70-77 8 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Prolonged changes in neurochemistry of dopamine neurones after chronic ethanol consumption

Bailey, C. P., Andrews, N., McKnight, A. T., Hughes, J. & Little, H. J., 1 May 2000, In : Pharmacology Biochemistry and Behavior. 66, 1, p. 153-161 9 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Protein kinase C activation enhances morphine-induced rapid desensitization of μ-opioid receptors in mature rat locus ceruleus neurons

Bailey, C. P., Kelly, E. & Henderson, G., 2004, In : Molecular Pharmacology. 66, 6, p. 1592-1598 7 p.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Reversal of morphine analgesic tolerance by ethanol in the mouse

Hull, L. C., Gabra, B. H., Bailey, C. P., Henderson, G. & Dewey, W. L., Jun 2013, In : Journal of Pharmacology and Experimental Therapeutics. 345, 3, p. 512-519 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization

Lowe, J. D., Sanderson, H. S., Cooke, A. E., Ostovar, M., Tsisanova, E., Withey, S. L., Chavkin, C., Husbands, S. M., Kelly, E., Henderson, G. & Bailey, C. P., Aug 2015, In : Molecular Pharmacology. 88, 2, p. 347-356

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
92 Downloads (Pure)

Role of group II metabotropic receptors in long-term plasticity of presynaptic vesicular release at glutamatergic synapses

Zhang, X. L., Nicholls, R. E., Bailey, C. P., Upreti, C., Muller, W., Kandel, E. R. & Stanton, P. K., 2011, In : Current Neuropharmacology. 9, Supplement 1, p. 69 1 p.

Research output: Contribution to journalArticle

Role of protein kinase C and μ-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons

Bailey, C. P., Llorente, J., Gabra, B. H., Smith, F. L., Dewey, W. L., Kelly, E. & Henderson, G., Jan 2009, In : European Journal of Neuroscience. 29, 2, p. 307-318 12 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)