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Chris Bailey

Dr

 https://orcid.org/0000-0003-0781-8887

  • 5 WEST 2.49C

Accepting Doctoral Students

19982020

Research output per year

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Research Output

2020

Morphine-induced respiratory depression is independent of β-arrestin2 signalling

Kliewer, A., Gillis, A., Hill, R., Schmidel, F., Bailey, C., Kelly, E., Henderson, G., Christie, M. J. & Schulz, S., 12 Feb 2020, In : British Journal of Pharmacology.

Research output: Contribution to journal › Article

Open Access
7 Citations (Scopus)

Voltage modulates the effect of μ receptor activation in a ligand-dependent manner

Ruland, J. G., Kirchhofer, S. B., Klindert, S., Bailey, C. P. & Bünemann, M., 16 Apr 2020, In : British Journal of Pharmacology.

Research output: Contribution to journal › Article

Open Access
2019

A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain

Conibear, A. E., Asghar, J., Hill, R., Henderson, G., Borbely, E., Tekus, V., Helyes, Z., Palandri, J., Bailey, C. P., Starke, I., von Mentzer, B., Kendall, D. & Kelly, E., 8 Oct 2019, In : Journal of Pharmacology and Experimental Therapeutics.

Research output: Contribution to journal › Article

Open Access
3 Citations (Scopus)

Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine-conditioned place preference and associated changes in AMPA receptor binding

Wright, V. L., Georgiou, P., Bailey, A., Heal, D. J., Bailey, C. P. & Wonnacott, S., 3 Jun 2019, In : Addiction Biology. 24, 4, p. 590-603 14 p.

Research output: Contribution to journal › Article

Open Access
5 Citations (Scopus)
21 Downloads (Pure)

Simultaneous Transdermal Delivery of Buprenorphine Hydrochloride and Naltrexone Hydrochloride by Iontophoresis

Cordery, S., Husbands, S., Bailey, C., Guy, R. & Delgado-Charro, M., 3 Jun 2019, In : Molecular Pharmaceutics. 16, 6, p. 2808-2816 9 p.

Research output: Contribution to journal › Article

Open Access
3 Citations (Scopus)
2018

Antidepressant-like effects of BU10119, a novel buprenorphine analogue with mixed κ/μ receptor antagonist properties, in mice

Almatroudi, A. M. I., Ostovar, M., Bailey, C., Husbands, S. & Bailey, S., 1 Jul 2018, In : British Journal of Pharmacology. 175, 14, p. 2869-2880 12 p.

Research output: Contribution to journal › Article

Open Access
File
12 Citations (Scopus)
49 Downloads (Pure)

Effects of kappa opioid receptor agonists and acute stress on brain regions implicated in the response to stress and drugs of abuse

Ma, Q., Wonnacott, S., Bailey, S. & Bailey, C., 1 Aug 2018, In : Journal of Psychopharmacology . 32, 8 (Supplement), p. A124

Research output: Contribution to journal › Meeting abstract

Emerging areas of opioid pharmacology

Kelly, E., Henderson, G. & Bailey, C. P., 1 Jul 2018, In : British Journal of Pharmacology. 175, 14, p. 2715-2716 2 p.

Research output: Contribution to journal › Editorial

File
170 Downloads (Pure)

Investigating the effects of sex on depression-related behaviour evoked by kappa opioid receptor activation in the forced swim test

Lalji, H., Sadler, A., Bailey, C. & Bailey, S., 1 Aug 2018, In : Journal of Psychopharmacology . 32, 8 (Supplement), p. A123

Research output: Contribution to journal › Meeting abstract

The novel μ-opioid receptor agonist PZM21 depresses respiration and induces tolerance to antinociception

Hill, R., Disney, A., Conibear, A., Sutcliffe, K., Dewey, W., Husbands, S., Bailey, C., Kelly, E. & Henderson, G., 1 Jul 2018, In : British Journal of Pharmacology. 175, 13, p. 2653-2661 9 p.

Research output: Contribution to journal › Article

Open Access
46 Citations (Scopus)
9 Downloads (Pure)
2017

Gender differences in kappa opioid receptor activated brain networks implicated in the response to stress and drugs of abuse

Ma, Q., Wonnacott, S., Bailey, S. & Bailey, C., 1 Aug 2017, (Acceptance date) In : Journal of Psychopharmacology . 31, 8, p. A132

Research output: Contribution to journal › Meeting abstract

Investigating the effects of gender on anxiety related behaviour evoked by kappa opioid receptor activation in the elevated plus maze

Lalji, H., Almatroudi, A. M. I., Bailey, C. & Bailey, S., 1 Aug 2017, (Acceptance date) In : Journal of Psychopharmacology . 31, 8, p. A21

Research output: Contribution to journal › Meeting abstract

2016

Ethanol reversal of tolerance to the respiratory depressant effects of morphine

Hill, R., Lyndon, A., Withey, S., Roberts, J., Kershaw, Y., MacLachlan, J., Lingford-Hughes, A., Kelly, E., Bailey, C., Hickman, M. & Henderson, G., 1 Feb 2016, In : Neuropsychopharmacology. 41, 3, p. 762-773 12 p.

Research output: Contribution to journal › Article

Open Access
29 Citations (Scopus)
42 Downloads (Pure)

Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity

Udakis, M., Wright, V., Wonnacott, S. & Bailey, C. P., 1 Jun 2016, In : Neuropharmacology. 105, p. 618-629 12 p.

Research output: Contribution to journal › Article

Open Access
7 Citations (Scopus)
86 Downloads (Pure)

Investigating the roles of kappa opioid receptors in neurochemical changes caused by stress and drugs of abuse

Ma, Q., Wonnacott, S., Bailey, S. & Bailey, C., 2016, In : pA2Online.

Research output: Contribution to journal › Meeting abstract

File
30 Downloads (Pure)
2015

Combined administration of buprenorphine and naltrexone produces antidepressant-like effects in mice

Almatroudi, A., Husbands, S. M., Bailey, C. P. & Bailey, S. J., 1 Jul 2015, In : Journal of Psychopharmacology . 29, 7, p. 812-821 10 p.

Research output: Contribution to journal › Article

Open Access
File
34 Citations (Scopus)
134 Downloads (Pure)

Functional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental area

Lowe, J. D. & Bailey, C. P., Jan 2015, In : British Journal of Pharmacology. 172, 2, p. 469-481 13 p.

Research output: Contribution to journal › Article

Open Access
12 Citations (Scopus)

Role of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and Internalization

Lowe, J. D., Sanderson, H. S., Cooke, A. E., Ostovar, M., Tsisanova, E., Withey, S. L., Chavkin, C., Husbands, S. M., Kelly, E., Henderson, G. & Bailey, C. P., Aug 2015, In : Molecular Pharmacology. 88, 2, p. 347-356

Research output: Contribution to journal › Article

Open Access
File
33 Citations (Scopus)
94 Downloads (Pure)

The antidepressant-like effects of BU10119, a novel kappa opioid receptor antagonist, in the novelty-induced hypophagia task in mice

Bailey, S., Almatroudi, A. M. I., Bailey, C. & Husbands, S., 2015, Neuroscience Meeting Planner : Society for Neuroscience. 774.09

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2014

A non-rewarding, non-aversive buprenorphine/naltrexone combination attenuates drug-primed reinstatement to cocaine and morphine in rats in a conditioned place preference paradigm

Cordery, S. F., Taverner, A., Ridzwan, I. E., Guy, R. H., Delgado-Charro, M. B., Husbands, S. M. & Bailey, C. P., 1 Jul 2014, In : Addiction Biology. 19, 4, p. 575-586 12 p.

Research output: Contribution to journal › Article

Open Access
File
30 Citations (Scopus)
191 Downloads (Pure)

Combination Treatment With Buprenorphine/Naltrexone, A Functional Kappa Opioid Receptor Antagonist, Produces Antidepressant-Like Effects In Mice

Almatroudi, A., Husbands, S. M., Bailey, C. P. & Bailey, S. J., Aug 2014, In : Journal of Psychopharmacology . 28, 8, p. A101 1 p.

Research output: Contribution to journal › Meeting abstract

Novel approaches for the treatment of psychostimulant and opioid abuse-focus on opioid receptor-based therapies

Bailey, C. P. & Husbands, S. M., Nov 2014, In : Expert Opinion on Drug Discovery. 9, 11, p. 1333-1344 12 p.

Research output: Contribution to journal › Article

Open Access
File
13 Citations (Scopus)
73 Downloads (Pure)

The antidepressant-like effects of combination buprenorphine/naltrexone in the novelty-induced hypophagia task in mice

Bailey, S., Almatroudi, A. M. I., Bailey, C. & Husbands, S., 2014, Neuroscience Meeting Planner: Society for Neuroscience. Online

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2013

Establishing the combination of buprenorphine and naltrexone as a functional kappa opioid receptor antagonist in mice

Almatroudi, A., Husbands, S. M., Bailey, C. P. & Bailey, S. J., 2013, In : Proceedings of the British Pharmacological Society.

Research output: Contribution to journal › Meeting abstract

Ethanol reversal of cellular tolerance to morphine in rat locus coeruleus neurons

Llorente, J., Withey, S., Rivero, G., Cunningham, M., Cooke, A., Saxena, K., McPherson, J., Oldfield, S., Dewey, W. L., Bailey, C. P., Kelly, E. & Henderson, G., Aug 2013, In : Molecular Pharmacology. 84, 2, p. 252-260 9 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Reversal of morphine analgesic tolerance by ethanol in the mouse

Hull, L. C., Gabra, B. H., Bailey, C. P., Henderson, G. & Dewey, W. L., Jun 2013, In : Journal of Pharmacology and Experimental Therapeutics. 345, 3, p. 512-519 8 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)
2012

Endomorphin-2: A biased agonist at the μ-opioid receptor

Rivero, G., Llorente, J., McPherson, J., Cooke, A., Mundell, S. J., McArdle, C. A., Rosethorne, E. M., Charlton, S. J., Krasel, C., Bailey, C. P., Henderson, G. & Kelly, E., 2012, In : Molecular Pharmacology. 82, 2, p. 178-188 11 p.

Research output: Contribution to journal › Article

64 Citations (Scopus)

μ-Opioid receptor desensitization: homologous or heterologous?

Llorente, J., Lowe, J. D., Sanderson, H. S., Tsisanova, E., Kelly, E., Henderson, G. & Bailey, C. P., Dec 2012, In : European Journal of Neuroscience. 36, 12, p. 3636-3642 6 p.

Research output: Contribution to journal › Article

13 Citations (Scopus)
2011

Elucidating agonist-selective mechanisms of G protein-coupled receptor desensitization

Bailey, C. P. & Kelly, E., 4 Aug 2011, Methods for the Discovery and Characterization of G Protein-Coupled Receptors. Stevens, C. W. (ed.). Humana Press, p. 323-346 24 p. (Neuromethods; vol. 60).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Lack of agonist-induced desensitization of mu-opioid receptors located at nerve terminals

Lowe, J. D. & Bailey, C. P., 2011, In : Pharmacological Reports. 63, 1, p. 235 1 p.

Research output: Contribution to journal › Article

Role of group II metabotropic receptors in long-term plasticity of presynaptic vesicular release at glutamatergic synapses

Zhang, X. L., Nicholls, R. E., Bailey, C. P., Upreti, C., Muller, W., Kandel, E. R. & Stanton, P. K., 2011, In : Current Neuropharmacology. 9, Supplement 1, p. 69 1 p.

Research output: Contribution to journal › Article

Transdermal delivery of a buprenorphine/naltrexone combination for the treatment of polydrug abuse

Taverner, A., Cordery, S., Husbands, S. M., Guy, R. H., Delgado-Charro, B. M. & Bailey, C. P., Jan 2011, In : Pharmacological Reports. 63, 1, p. 257 1 p.

Research output: Contribution to journal › Meeting abstract

2010

The effect of protein kinase C and G protein-coupled receptor kinase inhibition on tolerance induced by mu-opioid agonists of different efficacy

Hull, L. C., Llorente, J., Gabra, B. H., Smith, F. L., Kelly, E., Bailey, C., Henderson, G. & Dewey, W. L., 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 3, p. 1127-1135 9 p.

Research output: Contribution to journal › Article

49 Citations (Scopus)

μ-Opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

McPherson, J., Rivero, G., Baptist, M., Llorente, J., Al-Sabah, S., Krasel, C., Dewey, W. L., Bailey, C. P., Rosethorne, E. M., Charlton, S. J., Henderson, G. & Kelly, E., Oct 2010, In : Molecular Pharmacology. 78, 4, p. 756-766 11 p.

Research output: Contribution to journal › Article

163 Citations (Scopus)
2009

Glutamate-induced post-activation inhibition of locus coeruleus neurons is mediated by AMPA/kainate receptors and sodium-dependent potassium currents

Zamalloa, T., Bailey, C. P. & Pineda, J., 2009, In : British Journal of Pharmacology. 156, 4, p. 649-661 13 p.

Research output: Contribution to journal › Article

16 Citations (Scopus)

Involvement of PKCα and G-protein-coupled receptor kinase 2 in agonist-selective desensitization of µ-opioid receptors in mature brain neurons

Bailey, C. P., Oldfield, S., Llorente, J., Caunt, C. J., Teschemacher, AG., Roberts, L., McArdle, CA., Smith, FL., Dewey, WL., Kelly, E. & Henderson, G., Sep 2009, In : British Journal of Pharmacology. 158, 1, p. 157-164 8 p.

Research output: Contribution to journal › Article

65 Citations (Scopus)

Role of protein kinase C and μ-opioid receptor (MOPr) desensitization in tolerance to morphine in rat locus coeruleus neurons

Bailey, C. P., Llorente, J., Gabra, B. H., Smith, F. L., Dewey, W. L., Kelly, E. & Henderson, G., Jan 2009, In : European Journal of Neuroscience. 29, 2, p. 307-318 12 p.

Research output: Contribution to journal › Article

65 Citations (Scopus)
2008

Agonist-selective mechanisms of GPCR desensitization

Kelly, E., Bailey, C. P. & Henderson, G., 2008, In : British Journal of Pharmacology. 153, S1, p. S379-S388

Research output: Contribution to journal › Article

254 Citations (Scopus)

C-terminal splice variants of the μ-opioid receptor: existence, distribution and functional characteristics

Oldfield, S., Braksator, E., Rodriguez-Martin, I., Bailey, C. P., Donaldson, L. F., Henderson, G. & Kelly, E., 2008, In : Journal of Neurochemistry. 104, 4, p. 937-945 9 p.

Research output: Contribution to journal › Article

13 Citations (Scopus)

Does alcohol increase the risk of overdose death: the need for a translational approach

Hickman, M., Lingford-Hughes, A., Bailey, C., Macleod, J., Nutt, D. & Henderson, G., 2008, In : Addiction. 103, 7, p. 1060-1062 3 p.

Research output: Contribution to journal › Article

31 Citations (Scopus)

Functional selectivity in GPCR desensitization

Bailey, C., Henderson, G. & Kelly, E., 2008, In : Fundamental & Clinical Pharmacology. 22, p. 7-7 1 p.

Research output: Contribution to journal › Article

Gαi2 inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses

Bailey, C. P., Nicholls, R. E., Zhang, X. L., Zhou, Z. Y., Muller, W., Kandel, E. R. & Stanton, P. K., 2008, In : Learning and Memory. 15, 4, p. 261-270 10 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

Methadone: Does it really have low efficacy at mu-opioid receptors?

Rodriguez-Martin, I., Braksator, E., Bailey, C. P., Goodchild, S., Marrion, N. V., Kelly, E. & Henderson, G., Mar 2008, In : Neuroreport. 19, 5, p. 589-593 5 p.

Research output: Contribution to journal › Article

15 Citations (Scopus)

Mu-opioid receptor internalisation: Studies using a pHluorin tag

Baptist, M., Braksator, E., Bailey, C., Kelly, E. & Henderson, G., 2008, In : Fundamental & Clinical Pharmacology. 22, p. 60-60 1 p.

Research output: Contribution to journal › Article

Pre-treatment with a PKC or PKA inhibitor prevents the development of morphine tolerance but not physical dependence in mice

Gabra, B. H., Bailey, C. P., Kelly, E., Smith, F. L., Henderson, G. & Dewey, W. L., 27 Jun 2008, In : Brain Research. 1217, p. 70-77 8 p.

Research output: Contribution to journal › Article

26 Citations (Scopus)

Understanding causal pathways: A response to the commentaries

Hickman, M., Lingford-Hughes, A., Bailey, C., Macleod, J., Nutt, D. & Henderson, G., 1 Jul 2008, In : Addiction. 103, 7, p. 1067-1068 2 p.

Research output: Contribution to journal › Comment/debate

1 Citation (Scopus)
2007

Evidence for an important role of protein phosphatases in the mechanism of morphine tolerance

Gabra, B. H., Bailey, C. P., Kelly, E., Sanders, A. V., Henderson, G., Smith, F. L. & Dewey, W. L., 2007, In : Brain Research. 1159, p. 86-93 8 p.

Research output: Contribution to journal › Article

17 Citations (Scopus)

Morphine tolerance: getting hooked

Bailey, C. P., 2007, In : The Biochemist. 29, p. 12-15 4 p.

Research output: Contribution to journal › Article

2006

Agonist-selective mechanisms of μ-opioid receptor desensitization in human embryonic kidney 293 cells

Johnson, E. A., Oldfield, S., Braksator, E., Gonzalez-Cuello, A., Couch, D., Hall, K. J., Mundell, S. J., Bailey, C. P., Kelly, E. & Henderson, G., 2006, In : Molecular Pharmacology. 70, 2, p. 676-685 10 p.

Research output: Contribution to journal › Article

123 Citations (Scopus)

How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance?

Bailey, C. P., Smith, F. L., Kelly, E., Dewey, W. L. & Henderson, G., 2006, In : Trends in Pharmacological Sciences. 27, 11, p. 558-565 8 p.

Research output: Contribution to journal › Article

70 Citations (Scopus)