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Barry Potter

Prof

1979 …2018
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Steryl-Sulfatase Medicine & Life Sciences
Derivatives Chemical Compounds
Sulfatases Medicine & Life Sciences
Aromatase Medicine & Life Sciences
Aromatase Inhibitors Medicine & Life Sciences
Cyclic ADP-Ribose Medicine & Life Sciences
Inositol Phosphates Chemical Compounds
Breast Neoplasms Medicine & Life Sciences

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Projects 2007 2018

Chemical Biology of Cellular Signalling using Polyphosphate Messengers

Potter, B.

1/01/14 → 31/12/18

Project: UK charity

A 500 MHz NMR Spectrometer to Underpin Biological and Medicinal Chemistry Research in the Department of Pharmacy and Pharmacology

Woodman, T. & Potter, B.

1/06/09 → 31/05/14

Project: UK charity

Cyclic Adenosine Diphosphoribose (cADPR) and Adenosine (ADPR) analogues in human T-lymphocyte chemical biology

Potter, B.

1/11/08 → 31/12/13

Project: UK charity

CHEMICAL BIOLOGY, INOSITOL PHOSPHATES AND CELL SIGNALLING

Potter, B. & Riley, A.

1/08/07 → 30/06/14

Project: UK charity

Research Output 1979 2018

A Fluorescent Probe Identifies Active Site Ligands of Inositol Pentakisphosphate 2-Kinase

Potter, B. & Godage, H., 30 Aug 2018, In : Journal of Medicinal Chemistry.

Research output: Contribution to journal › Article

Inositol Phosphates
Fluorescent Dyes
Catalytic Domain
Ligands
Phosphotransferases

Quinazolinone-based Anticancer Agents: Synthesis, Anti-proliferative SAR, Anti-tubulin Activity and Tubulin Co-crystal Structure

Dohle, W., Jourdan, F., Menchon, G., Prota, A., Foster, P. A., Mannion, P., Hamel, E., Thomas, M., Kasprzyk, P. G., Ferrandis, E., Steinmetz, M. O., Leese, M. & Potter, B., 2018, (Unpublished) In : Journal of Medicinal Chemistry. 49 p.

Research output: Contribution to journal › Article

Quinazolinones
Tubulin
Steryl-Sulfatase
Antineoplastic Agents
Colchicine

Small Molecule Antagonists of NAADP-Induced Ca2+ Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease

Potter, B., Watt, J. M., Zhang, B. & Mahon, M., 28 Oct 2018, (Accepted/In press) In : Scientific Reports.

Research output: Contribution to journal › Article

Synthetic cADPR analogues may form only one of two possible conformational diastereoisomers

Potter, B., Thomas, M. & Watt, J. M., 27 Sep 2018, (Accepted/In press) In : Scientific Reports.

Research output: Contribution to journal › Article

Ribose
Diphosphates
Adenosine
Cyclization
Adenine
7 Citations

2ʹ-Deoxyadenosine 5ʹ-diphosphoribose is an endogenous TRPM2 superagonist

Fliegert, R., Bauche, A., Wolf Pérez, A-M., Watt, J. M., Rozewitz, M. D., Winzer, R., Janus, M., Gu, F., Rosche, A., Harneit, A., Flato, M., Moreau, C., Kirchberger, T., Wolters, V., Potter, B. V. L. & Guse, A. H., 2017, In : Nature Chemical Biology. 13, p. 1036-1044

Research output: Contribution to journal › Article

Open Access
File
Nicotinamide-Nucleotide Adenylyltransferase
Nicotinamide Mononucleotide
Adenosine Diphosphate Ribose
Glycoside Hydrolases
NAD