Personal profile

Research interests

Banafshé Larijani is the Director of the Centre for Therapeutics Innovation (CTI) at the University of Bath. CTI is an Internationally faced research and innovation Centre with the mission to transform innovation, arising from cross-disciplinary research to quantitative diagnostics & medicines-design, leading to precision medicine.
Her laboratory, Cell Biophysics, since 2001 in the UK and Spain has been the core of an international network that spans from the physical sciences, engineering, life sciences to translational science.
Professor Larijani's laboratory is a cutting-edge cross-disciplinary platform, that has drawn upon the physical sciences to develop novel avenues for investigation of biological processes in signalling pathways. Her laboratory has led to paving a unique path by investigating the role of phosphoinositides and their metabolites, both as second messengers and as modulators of membrane morphology, exploiting both marine and mammalian models. The outcomes of her fundamental research, involving the application of quantitative imaging (FRET-FLIM) for investigating molecular mechanisms and dynamics of phosphoinositide-modifying and phosphoinositide-dependant enzymes have resulted in their application to various clinical objectives.
While in the Basque Country (2014-2018), Spain, the cancer diagnostic/prognostic company, she co-founded and directed, FASTBASE SOLUTIONS S.L., won European and French Awards for best “predictive cancer diagnostic test”.
Since 2002, she has trained 19 PhD Students, three of whom were clinicians. As senior author, she has published 100 primary research articles, majority leading to novel concepts in nuclear envelope biogenesis, lipid signalling and cancer biology.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water

Education/Academic qualification

Molecular Biology and Biochemistry , Doctor of Science, University of Massachusetts

Award Date: 4 May 1999

External positions

Co-Founder, Co-Director and Chief Scientific Officer , FASTBASE SOLUTIONS Ltd

1 Nov 201530 Sept 2021

Keywords

  • QC Physics
  • Biophysics
  • QH301 Biology
  • Biochemistry
  • Signal Transduction
  • Membrane Biology
  • Quantitative imaging
  • Lipid signalling

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