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20132020
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Personal profile

Research interests

Banafshé Larijani is the Director of the Centre for Therapeutic Innovation (CTI). Her laboratory, Cell Biophysics, is currently bridged between the Department of Pharmacy and Pharmacology at University of Bath and The Biophysics Institute (Instituto Biofisika) at the University of the Basque Country, Spain.  Since 2002 she was Head of Cell Biophysics Laboratory at Cancer Research UK, was appointed Senior Scientist in 2012 and in 2014 was awarded an Ikerbasque Research Professorship where she moved her laboratory to the Biophysics Institute and the Research Centre for Experimental Marine Biology and Biotechnology (PiE) Bilbao, Spain. She holds adjunct professorships with Stony Brooks University NY and University of Massachusetts, Amherst MA, (USA).

Professor Larijani's laboratory is a cutting edge cross-disciplinary platform, which draws upon the physical sciences to develop novel avenues for investigation of biological processes in signalling. Her laboratory has led to paving a unique path by investigating the role of phosphoinositides and their metabolites, both as second messengers and as modulators of membrane morphology. The outcomes of her fundamental research involving the application of quantitative imaging (FRET-FLIM) for investigating molecular mechanisms of phosphoinositide-modifying and phosphoinositide-dependant enzymes have resulted in their application to various clinical objectives.

While in the  Basque Country (2014) her laboratory and her new cancer diagnostic/prognostic company, FASTBASE SOLUTIONS Ltd, have been awarded 6 peer-reviewed grants. Prior to that all laboratory funding was based on core-funding at Cancer Research UK. Since 2002 she has more than published 90 primary research articles in the area of nuclear envelope biogenesis, lipid signalling and cancer biology and has over 2600 citations.

Education/Academic qualification

Molecular Biology and Biochemistry , Doctor of Science, University of Massachusetts

External positions

Chief Scientific Officer , FASTBASE SOLUTIONS Ltd

1 Nov 2015 → …

Keywords

  • QC Physics
  • Biophysics
  • QH301 Biology
  • Biochemistry
  • Signal Transduction
  • Membrane Biology
  • Quantitative imaging
  • Lipid signalling

Fingerprint Dive into the research topics where Banafshe Larijani is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2019 2020

MRC P2D - Showcase Event (2)

Larijani, B.

25/02/1930/06/20

Project: Research council

Research Output 2013 2018

Acute depletion of diacylglycerol from the cis-Golgi affects localized nuclear envelope morphology during mitosis

Chung, G. H. C., Domart, M-C., Peddie, C., Mantell, J., Mclaverty, K., Arabiotorre, A., Hodgson, L., Byrne, R. D., Verkade, P., Arkill, K., Collinson, L. M. & Larijani, B., 1 Aug 2018, In : Journal of Lipid Research. 59, 8, p. 1402-1413 12 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Polarized two-photon photoselection in EGFP: Theory and experiment

Masters, T. A., Marsh, R. J., Blacker, T. S., Armoogum, D. A., Larijani, B. & Bain, A. J., 6 Apr 2018, In : Journal of Chemical Physics. 148, 13, 134311.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Quantifying intracellular equilibrium dissociation constants using single-channel time-resolved FRET

de Las Heras-Martínez, G., Andrieu, J., Larijani, B. & Requejo-Isidro, J., Jan 2018, In : Journal of Biophotonics. 11, 1, 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Time-resolved stimulated emission depletion and energy transfer dynamics in two-photon excited EGFP

Masters, T. A., Robinson, N. A., Marsh, R. J., Blacker, T. S., Armoogum, D. A., Larijani, B. & Bain, A. J., 6 Apr 2018, In : Journal of Chemical Physics. 148, 13, 134312.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo

Peddie, C. J., Domart, M-C., Snetkov, X., O'Toole, P., Larijani, B., Way, M., Cox, S. & Collinson, L. M., Aug 2017, In : Journal of Structural Biology. 199, 2, p. 120-131 12 p.

Research output: Contribution to journalArticle

Open Access