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Research Output 2001 2019

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Article
2019

Conditional expression explains molecular evolution of social genes in a microbe

de Oliveira, J. L., Morales, A. C., Stewart, B., Gruenheit, N., Engelmoer, J., Brown, S. B., de Brito, R. A., Hurst, L. D., Urrutia, A. O., Thompson, C. R. L. & Wolf, J. B., 23 Jul 2019, In : Nature Communications. 10, 1, p. 1-12 12 p., 3284.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Conserved transcriptomic profiles underpin monogamy across vertebrates

Young, R. L., Ferkin, M. H., Ockendon-Powell, N. F., Orr, V. N., Phelps, S. M., Pogány, Á., Richards-Zawacki, C. L., Summers, K., Székely, T., Trainor, B. C., Urrutia, A. O., Zachar, G., O’Connell, L. A. & Hofmann, H. A., 22 Jan 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 4, p. 1331-1336 6 p.

Research output: Contribution to journalArticle

Postmitotic cell longevity–associated genes: a transcriptional signature of postmitotic maintenance in neural tissues

Castillo-Morales, A., Monzón-Sandoval, J., Urrutia, A. O. & Gutiérrez, H., 1 Feb 2019, In : Neurobiology of Aging. 74, p. 147-160 14 p.

Research output: Contribution to journalArticle

2017
1 Citation (Scopus)
developmental biology
Developmental Biology
evolutionary biology
Genomics
genomics
2016
1 Citation (Scopus)
85 Downloads (Pure)

Modular reorganization of the global network of gene regulatory interactions during perinatal human brain development

Monzón Sandoval, J., Castillo Morales, A., Urrutia, A. & Gutierrez, H., 12 May 2016, In : BMC Developmental Biology. 16, 13.

Research output: Contribution to journalArticle

Open Access
File
Gene Regulatory Networks
Human Development
Transcriptome
Brain
Parturition

Neocortex expansion is linked to size variations in gene families with chemotaxis, cell-cell signalling and immune response functions in mammals

Castillo-Morales, A., Monzón-Sandoval, J., de Sousa, A. A., Urrutia, A. O. & Gutierrez, H., 2016, In : Open Biology. 6, 10, 3489039.

Research output: Contribution to journalArticle

Open Access
Cell signaling
Mammals
Neocortex
Chemotaxis
Genes
10 Citations (Scopus)

Optimization of next-generation sequencing transcriptome annotation for species lacking sequenced genomes

Ockendon, N. F., O'Connell, L. A., Bush, S. J., Monzón Sandoval, J., Barnes, H., Szekely, T., Hofmann, H. A., Dorus, S. & Urrutia, A. O., Mar 2016, In : Molecular Ecology Resources. 16, 2, p. 446-458

Research output: Contribution to journalArticle

Open Access
2015
6 Citations (Scopus)

Alternative splice in alternative lice

Tovar-Corona, J. M., Castillo-Morales, A., Chen, L., Olds, B. P., Clark, J. M., Reynolds, S. E., Pittendrigh, B. R., Feil, E. J. & Urrutia, A. O., 1 Oct 2015, In : Molecular Biology and Evolution. 32, 10, p. 2749-2759 11 p.

Research output: Contribution to journalArticle

Open Access
Pediculus humanus
Pediculus humanus capitis
Pediculus
Phthiraptera
louse
4 Citations (Scopus)
exons
Exons
gene
genomics
substitution
107 Citations (Scopus)
89 Downloads (Pure)

YAP is essential for tissue tension to ensure vertebrate 3D body shape

Porazinski, S., Wang, H., Asaoka, Y., Behrndt, M., Miyamoto, T., Morita, H., Hata, S., Sasaki, T., Krens, S. F. G., Osada, Y., Asaka, S., Momoi, A., Linton, S., Miesfeld, J. B., Link, B. A., Senga, T., Castillo-Morales, A., Urrutia, A. O., Shimizu, N., Nagase, H. & 6 others, Matsuura, S., Bagby, S., Kondoh, H., Nishina, H., Heisenberg, C. P. & Furutani-Seiki, M., 14 May 2015, In : Nature. 521, 7551, p. 217-221 5 p.

Research output: Contribution to journalArticle

Open Access
File
Vertebrates
Gravitation
Oryzias
Embryonic Structures
Actomyosin
2014
51 Citations (Scopus)
50 Downloads (Pure)

Correcting for differential transcript coverage reveals a strong relationship between alternative splicing and organism complexity

Chen, L., Bush, S. J., Tovar-Corona, J. M., Castillo Morales, A. & Urrutia, A. O., 1 Jun 2014, In : Molecular Biology and Evolution. 31, 6, p. 1402-1413 12 p.

Research output: Contribution to journalArticle

Open Access
alternative splicing
Alternative Splicing
organisms
genomics
genome
17 Citations (Scopus)
92 Downloads (Pure)
Open Access
File
genomics
gene
Genes
genes
exons
2013
5 Citations (Scopus)
87 Downloads (Pure)

Evidence for deep phylogenetic conservation of exonic splice-related constraints: Splice-related skews at exonic ends in the brown alga Ectocarpus are common and resemble those seen in humans

Wu, X., Tronholm, A., Fernandez Cáceres, E., Tovar-Corona, J. M., Chen, L., Urrutia, A. O. & Hurst, L. D., 2013, In : Genome biology and evolution. 5, 9, p. 1731-1745 15 p.

Research output: Contribution to journalArticle

Open Access
File
Phaeophyta
Phaeophyceae
brown alga
codons
Codon
50 Citations (Scopus)
X Chromosome Inactivation
inactivation
X-Linked Genes
gene
Genes
7 Citations (Scopus)
85 Downloads (Pure)
Open Access
File
Cell signaling
chemotaxis
Mammals
Chemotaxis
brain
2012
67 Downloads (Pure)

Alternative splicing: Α potential source of functional innovation in the eukaryotic genome

Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 2012, In : International Journal of Evolutionary Biology. 2012, 10 p., 596274.

Research output: Contribution to journalArticle

Open Access
File
Alternative Splicing
Genome
Genes
Human Genome
Proteins
2011
18 Citations (Scopus)
82 Downloads (Pure)

Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts

Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 15 Nov 2011, In : Human Molecular Genetics. 20, 22, p. 4422-4429 8 p.

Research output: Contribution to journalArticle

File
Oncogenes
Nonsense Codon
Alternative Splicing
Neoplasms
Tumor Suppressor Genes
4 Citations (Scopus)
75 Downloads (Pure)

Protein amino acid composition: a genomic signature of encephalization in mammals

Gutierrez, H., Castillo Morales, A., Monzon, J. & Urrutia, A. O., 23 Nov 2011, In : PLoS ONE. 6, 11, 5 p., e27261.

Research output: Contribution to journalArticle

File
Mammals
amino acid composition
Brain
Genes
mammals
2008
17 Citations (Scopus)
61 Downloads (Pure)

Do Alu repeats drive the evolution of the primate transcriptome?

Urrutia, A. O., Ocana, L. B. & Hurst, L. D., 1 Feb 2008, In : Genome Biology. 9, 2, 16 p., R25.

Research output: Contribution to journalArticle

File
Transcriptome
transcriptome
primate
Primates
gene
2007
63 Citations (Scopus)

Chromatin remodelling is a major source of coexpression of linked genes in yeast

Batada, N. N., Urrutia, A. O. & Hurst, L. D., 2007, In : Trends in Genetics. 23, 10, p. 480-484 5 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Yeasts
Genes
Gene Order
Genetic Therapy
66 Citations (Scopus)

Splicing and the evolution of proteins in mammals

Parmley, J. L., Urrutia, A. O., Potrzebowski, L., Kaessmann, H. & Hurst, L. D., 2007, In : PLoS Biology. 5, 2, e14.

Research output: Contribution to journalArticle

Protein Splicing
Mammals
Introns
introns
exons
2003
94 Citations (Scopus)

A unification of mosaic structures in the human genome

Lercher, M. J., Urrutia, A. O., Pavlicek, A. & Hurst, L. D., 2003, In : Human Molecular Genetics. 12, 19, p. 2411-2415 5 p.

Research output: Contribution to journalArticle

Base Composition
Human Genome
Isochores
Chromosome Structures
Essential Genes
77 Citations (Scopus)

Evidence that the human X chromosome is enriched for male-specific but not female-specific genes

Lercher, M. J., Urrutia, A. O. & Hurst, L. D., 7 Jul 2003, In : Molecular Biology and Evolution. 20, 7, p. 1113-1116 4 p.

Research output: Contribution to journalArticle

Chromosomes, Human, X
X chromosome
chromosome
gene
Genes
178 Citations (Scopus)

The signature of selection mediated by expression on human genes

Urrutia, A. O. & Hurst, L. D., 2003, In : Genome Research. 13, 10, p. 2260-2264 5 p.

Research output: Contribution to journalArticle

Genes
Population Density
Codon
Amino Acids
Genetic Selection
2002
412 Citations (Scopus)

Clustering of housekeeping genes provides a unified model of gene order in the human genome

Lercher, M. J., Urrutia, A. O. & Hurst, L. D., 2002, In : Nature Genetics. 31, 2, p. 180-183 4 p.

Research output: Contribution to journalArticle

Gene Order
Essential Genes
Human Genome
Cluster Analysis
Genes
2001
108 Citations (Scopus)
Codon
Nucleotides
Genes
Artifacts
Drosophila