Projects per year
Personal profile
Research interests
Research Interests
My research interests are in medication utilisation and medication safety in vulnerable populations, especially those not usually included in phase III clinical trials. I also undertake research into epidemiology of autoimmune diseases and occurrence of serious outcomes. I am a statistician and develop statistical models for these research projects. Most of the research that I do uses anonymised primary care records from the Clinical Practice Research Datalink (CPRD).
Medication use and safety in pregnancy
This research group has considerable experience in carrying out medication utilisation and safety studies in pregnant women using CPRD data. We have our own algorithm to identify pregnancies and outcomes that has been developed and refined over many years. We have used this to evaluate the prescribing and safety of medications for epilepsy, diabetes, high cholesterol, depression and asthma during pregnancy.
Medication use and safety in older people
Older people, especially those with many comorbidities, do not participate in clinical trials therefore being able to use the CPRD to investigate disease occurrence, prescribing and medication safety gives considerable insight into the health of these populations especially very frail or the oldest patients. Areas of interest include dementia, rheumatoid diseases, cerebrovascular disease and diabetes.
Epidemiology of autoimmune diseases
Current work includes evaluating incidence, prevalence and outcomes associated with systemic sclerosis to try to better understand prognosis of this disease and its effects. As a rare disease, work is being undertaken to evaluate different statistical models to use in evaluating time to event models that incorporate both incident and prevalent cases of disease and outcomes.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Pharmacy research priorities in the South-West: engaging and involving patients, the public and healthcare professionals
Jones, M. (PI), Jones, S. (CoI), McGrogan, A. (CoI), Rennie, T. (CoI), Slatter, M. (CoI) & Mitchell, A. (CoI)
1/02/24 → …
Project: Research-related funding
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Using big data to investigate foetal and child outcomes following exposure to antiepileptics in pregnancy
McGrogan, A. (PI), Charlton, R. (Researcher) & Ehrhardt, B. (Researcher)
1/10/23 → 31/03/26
Project: UK charity
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SLE and pregnancy
McGrogan, A. (PI) & Charlton, R. (Researcher)
Bath Institute For Rheumatic Diseases
1/08/25 → 30/09/26
Project: UK charity
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Validity of the Myositis Muscle Dysfunction Scale (MMDS) in adult patients with Polymyositis and Dermatomyositis
McGrogan, A. (CoI), Lange, E. (PI) & McHugh, N. (CoI)
Project: UK charity
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Dementia and serious health outcomes: a cohort and case control study investigating psychological distress as a risk factor
McGrogan, A. (PI), Welsh, T. J. (CoI) & Jarvis, A. (Researcher)
Project: Other
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Cardiovascular and venous thromboembolic events in systemic sclerosis: Epidemiological analysis of the Clinical Practice Research Datalink
Pauling, J., Charlton, R., Ross, L., McHugh, N. & McGrogan, A., 30 May 2025, In: Rheumatology.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Diagnostic delay and less intensive therapy for people with psoriatic arthritis compared with rheumatoid arthritis: a study nested within an English and Welsh audit data set
Charlton, R., Gates, E., Coates, L., Galloway, J., McHugh, N., McGrogan, A., Hackett, S., Brooke, M., Cavill, C. & Tillett, W., 29 Mar 2025, (E-pub ahead of print) In: Annals of the Rheumatic Diseases.Research output: Contribution to journal › Article › peer-review
Open Access -
Identifying and Predicting Risk for Hospital Admission among Patients with Parkinsonism
Tenison, E., McGrogan, A., Ben-Shlomo, Y. & Henderson, E., 31 Jan 2025, In: Movement Disorders Clinical Practice. 12, 1, p. 43-56 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Safety and effectiveness of anticoagulation therapy in older people with atrial fibrillation during exposed and unexposed treatment periods
Mitchell, A., Welsh, T. J., Watson, M. C. & McGrogan, A., 17 Feb 2025, (E-pub ahead of print) In: Heart.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (SciVal) -
Systemic sclerosis and cancer in the UK: An epidemiological analysis using the Clinical Practice Research Datalink
Pauling, J. D., McHugh, N. & McGrogan, A., 30 Apr 2025, In: Rheumatology. 64, 4, p. 1959–1965 7 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Dataset for "User-testing guidelines to improve the safety of intravenous medicines administration: a randomised in-situ simulation study"
Jones, M. (Creator), McGrogan, A. (Creator), Raynor, D. K. (Creator), Watson, M. (Creator) & Franklin, B. D. (Creator), University of Bath, 3 Jun 2020
DOI: 10.15125/BATH-00751
Dataset
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Dataset for "Temporal and geographical variation in low carbon inhaler dispensing in England, 2016 to 2021: an ecological study"
Tian, J. (Creator), McGrogan, A. (Creator) & Jones, M. (Creator), University of Bath, 16 Nov 2022
DOI: 10.15125/BATH-01142
Dataset
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Primary Care Data for Health Research
McGrogan, A. (Speaker)
3 Oct 2024Activity: Public, Community and School Engagement › Public talk, lecture, debate, seminar, workshop
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Member of Digital and Data Science Ethics Committee (Event)
McGrogan, A. (No value)
1 Apr 2023 → 1 Sept 2024Activity: Other contribution to the discipline › Role on a committee, board or panel
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Epilepsy Research Institute UK (External organisation)
McGrogan, A. (No value)
1 Nov 2023Activity: Other contribution to the discipline › Role on a committee, board or panel