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Personal profile

Research interests

My research sits at the intersection of chemistry and biology, focusing on the creation of novel chemistries to help understand biological processes and exploit the potential of biological molecules for societal benefit, in particular the development of novel biological therapeutics.

Research projects in our group include:

  • Small molecule covalent inhibitors of enzymes involved in disease.
  • Mono-alkylating bioconjugation chemistries for development of antibody-drug conjugates.
  • Methodologies to expand bioconjugate modalities.
  • Controlling effector function of monoclonal antibodies through chemical modification.
  • Disulphide re-bridging strategies for creation of bi-specific and tri-specific antibody conjugates
  • Targeted delivery of RNA-based therapeutics

 

 

Other responsibilities

Director of Knowledge Exchange, Faculty of Science.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Organic Chemistry, Doctor of Philosophy, The University of Western Australia

Award Date: 1 Apr 2001

Organic Chemistry, Bachelor of Science, The University of Western Australia

Award Date: 1 Nov 1996

External positions

Post-Doctoral Research Fellow, University of British Columbia

20022004

Keywords

  • Chemical Biology
  • Bioconjugation
  • Therapeutic Antibodies
  • Protein Conjugates
  • Chemical Immunology

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