Andrew Chalmers

Dr

  • 4 SOUTH 0.44

Accepting PhD Students

19982018
If you made any changes in Pure these will be visible here soon.

Research Output 1998 2018

Filter
Article
2017
4 Citations (Scopus)
21 Downloads (Pure)

A subset of high Gleason grade prostate carcinomas contain a large burden of prostate cancer syndecan-1 positive stromal cells

Sharpe, B., Alghezi, D. A., Cattermole, C., Beresford, M., Bowen, R., Mitchard, J. & Chalmers, A. D., 15 Sep 2017, In : Prostate. 77, 13, p. 1312-1324 13 p., 23391.

Research output: Contribution to journalArticle

Open Access
File
Syndecan-1
Stromal Cells
Prostate
Prostatic Neoplasms
Carcinoma
5 Citations (Scopus)

Cell surface dynamics and cellular distribution of endogenous FcRn

D'Hooghe, L., D Chalmers, A., Heywood, S. & Whitley, P., 17 Aug 2017, In : PLoS ONE. 12, 8, e0182695.

Research output: Contribution to journalArticle

Open Access
Immunoglobulin G
Endocytosis
endocytosis
recycling
albumins
2016
1 Citation (Scopus)
57 Downloads (Pure)

Truncated RASSF7 promotes centrosomal defects and cell death

Gulsen, T., Hadjicosti, I., Li, Y., Zhang, X., Whitley, P. R. & Chalmers, A. D., 15 Jan 2016, In : Developmental Biology. 409, 2, p. 502-517 16 p.

Research output: Contribution to journalArticle

Open Access
File
Centrosome
Cell Death
Proteins
Tubulin
Oncogenes
2015
262 Citations (Scopus)

Reproducibility: Standardize antibodies used in research

Chalmers, A. & Bradbury, A., Feb 2015, In : Nature. 518, 7537, p. 27 - 29 3 p.

Research output: Contribution to journalArticle

2014
11 Citations (Scopus)
86 Downloads (Pure)

CiteAb: A searchable antibody database that ranks antibodies by the number of times they have been cited

Helsby, M. A., Leader, P. M., Fenn, J. R., Gulsen, T., Bryant, C., Doughton, G., Sharpe, B., Whitley, P., Caunt, C. J., James, K., Pope, A. D., Kelly, D. H. & Chalmers, A. D., 14 Feb 2014, In : BMC Cell Biology. 15, 1, 6.

Research output: Contribution to journalArticle

Open Access
File
Databases
Antibodies
Publications
Research Personnel
Research
6 Citations (Scopus)
36 Downloads (Pure)

Formation of a polarised primitive endoderm layer in embryoid bodies requires Fgfr/Erk signalling

Doughton, G., Wei, J., Tapon, N., Welham, M. J. & Chalmers, A. D., 2014, In : PLoS ONE. 9, 4, e95434.

Research output: Contribution to journalArticle

Open Access
File
Embryoid Bodies
Endoderm
Polarization
cells
receptors
4 Citations (Scopus)
63 Downloads (Pure)

The F1000Research Antibody Validation Article Collection

Helsby, M. A., Leung, M. Y. & Chalmers, A. D., 11 Nov 2014, In : F1000 Research. 3, 241

Research output: Contribution to journalArticle

Open Access
File
Antibodies
Validation Studies
Biological Science Disciplines
Research Personnel
2013
15 Citations (Scopus)
19 Downloads (Pure)

A dual role for the βPS integrin myospheroid in mediating Drosophila embryonic macrophage migration

Comber, K., Huelsmann, S., Evans, I., Sánchez-Sánchez, B. J., Chalmers, A., Reuter, R., Wood, W. & Martín-Bermudo, M. D., 1 Aug 2013, In : Journal of Cell Science. 126, 15, p. 3475-3484 10 p.

Research output: Contribution to journalArticle

Open Access
File
Hemocytes
Integrins
Drosophila
Macrophages
Embryonic Structures
17 Citations (Scopus)
58 Downloads (Pure)

Reporting research antibody use: How to increase experimental reproducibility

Helsby, M., Fenn, J. & Chalmers, A., 2013, In : F1000 Research. 2, 153 v2.

Research output: Contribution to journalArticle

Open Access
File
Antibodies
Research
Publications
Research Personnel
Biological Science Disciplines
33 Citations (Scopus)
83 Downloads (Pure)

Searching for prostate cancer stem cells: markers and methods

Sharpe, B., Beresford, M., Bowen, R., Mitchard, J. & Chalmers, A. D., Oct 2013, In : Stem Cell Reviews and Reports. 9, 5, p. 721-730

Research output: Contribution to journalArticle

Open Access
File
Neoplastic Stem Cells
Prostatic Neoplasms
Colony-Forming Units Assay
Neoplasms
Transgenic Mice
2012
15 Citations (Scopus)
66 Downloads (Pure)

Continuous endocytic recycling of tight junction proteins: how and why?

Chalmers, A. & Whitley, P., 2012, In : Essays in Biochemistry. 53, p. 41-54 14 p.

Research output: Contribution to journalArticle

Open Access
File
Tight Junction Proteins
Tight Junctions
Recycling
Protein Transport
Endocytosis
28 Citations (Scopus)
49 Downloads (Pure)
Open Access
File
Claudin-2
Zonula Occludens-1 Protein
Claudin-1
Tight Junction Proteins
Madin Darby Canine Kidney Cells
2011
38 Citations (Scopus)

Epigenetic inactivation of the RASSF10 candidate tumor suppressor gene is a frequent and an early event in gliomagenesis

Hill, V. K., Underhill-Day, N., Krex, D., Robel, K., Sangan, C. B., Summersgill, H. R., Morris, M., Gentle, D., Chalmers, A. D., Maher, E. R. & Latif, F., Feb 2011, In : Oncogene. 30, 8, p. 978-989 12 p.

Research output: Contribution to journalArticle

Astrocytoma
Tumor Suppressor Genes
Epigenomics
Glioma
Glioblastoma
37 Citations (Scopus)
72 Downloads (Pure)

Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells

Dukes, J. D., Fish, L., Richardson, J. D., Blaikley, E., Burns, S., Caunt, C. J., Chalmers, A. D. & Whitley, P., 1 Sep 2011, In : Molecular Biology of the Cell. 22, 17, p. 3192-3205 14 p.

Research output: Contribution to journalArticle

File
Endosomal Sorting Complexes Required for Transport
Claudin-1
Recycling
Vertebrates
Epithelial Cells
92 Citations (Scopus)
50 Downloads (Pure)

The MDCK variety pack: choosing the right strain

Dukes, J. D., Whitley, P. & Chalmers, A. D., 7 Oct 2011, In : BMC Cell Biology. 12, 43.

Research output: Contribution to journalArticle

Open Access
File
Madin Darby Canine Kidney Cells
Research Personnel
Adherens Junctions
Directories
Desmosomes
2010
21 Citations (Scopus)
59 Downloads (Pure)

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

Recino, A., Sherwood, V., Flaxman, A., Cooper, WN., Latif, F., Ward, A. & Chalmers, A. D., 1 Sep 2010, In : Biochemical Journal. 430, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cytoskeleton
Mitosis
Microtubules
Chemical activation
Cells

RASSF7: a new possible therapeutic cancer target?

Recino, A., Flaxman, A., Sherwood, V., Cooper, W., Ward, A., Latif, F. & Chalmers, A. D., Feb 2010, In : Genetics Research. 92, 1, p. 71-72 2 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-κB signaling pathways

Lock, F. E., Underhill-Day, N., Dunwell, T., Matallanas, D., Cooper, W., Hesson, L., Recino, A., Ward, A., Pavlova, T., Zabarovsky, E., Grant, M. M., Maher, E. R., Chalmers, A. D., Kolch, W. & Latif, F., 2010, In : Oncogene. 29, 30, p. 4307-4316 10 p.

Research output: Contribution to journalArticle

Wnt Proteins
beta Catenin
Adherens Junctions
Growth
Cadherins
2009
Neurogenesis
Xenopus
Phosphotransferases
Cell Proliferation
Cell Polarity

Bmp4 promotes differentiation of the first vertebrate epithelium

Wei, J., Sanchez Ripoll, Y., Welham, M. & Chalmers, A. D., 2009, In : Mechanisms of Development. 126, Suppl S, p. S271

Research output: Contribution to journalArticle

Vertebrates
Epithelium
Epithelial Cells
Xenopus
Embryonic Structures
37 Citations (Scopus)

The apicobasal polarity kinase aPKC functions as a nuclear determinant and regulates cell proliferation and fate during Xenopus primary neurogenesis

Sabherwal, N., Tsutsui, A., Hodge, S., Wei, J., Chalmers, A. D. & Papalopulu, N., 15 Aug 2009, In : Development. 136, 16, p. 2767-2777 11 p.

Research output: Contribution to journalArticle

Neurogenesis
Xenopus
Phosphotransferases
Cell Proliferation
Cell Polarity
76 Citations (Scopus)
52 Downloads (Pure)

The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias

Hesson, L. B., Dunwell, T. L., Cooper, W. N., Catchpoole, D., Brini, A. T., Chiaramonte, R., Griffiths, M., Chalmers, A. D., Maher, E. R. & Latif, F., 1 Jul 2009, In : Molecular Cancer. 8, 42

Research output: Contribution to journalArticle

File
Tumor Suppressor Genes
Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma
B-Cell Leukemia
Methylation
2008
47 Citations (Scopus)
63 Downloads (Pure)

RASSF7 is a member of a new family of RAS association domain- containing proteins and is required for completing mitosis

Sherwood, V., Manbodh, R., Sheppard, C. & Chalmers, A. D., 1 Apr 2008, In : Molecular Biology of the Cell. 19, 4, p. 1772-1782 11 p.

Research output: Contribution to journalArticle

File
Mitosis
Neural Tube
Centrosome
Proteins
Spindle Apparatus
2006
39 Citations (Scopus)
67 Downloads (Pure)

Grainyhead-like 3, a transcription factor identified in a microarray screen, promotes the specification of the superficial layer of the embryonic epidermis

Chalmers, A., Lachani, K., Shin, Y., Sherwood, V., Cho, K. & Papalopulu, N., Sep 2006, In : Mechanisms of Development. 123, 9, p. 702-718 17 p.

Research output: Contribution to journalArticle

File
Transcription Factor 3
Epidermis
Ectoderm
Gastrula
Genes
2005
100 Citations (Scopus)

aPKC, Crumbs3 and Lgl2 control apicobasal polarity in early vertebrate development

Chalmers, A. D., Pambos, M., Mason, J., Lang, S., Wylie, C. & Papalopulu, N., 2005, In : Development. 132, 5, p. 977-986 10 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

A Xenopus tropicalis oligonucleotide microarray works across species using RNA from Xenopus laevis

Chalmers, A. D., Goldstone, K., Smith, J. C., Gilchrist, M., Amaya, E. & Papalopulu, N., 2005, In : Mechanisms of Development. 122, 3, p. 355-363 9 p.

Research output: Contribution to journalArticle

166 Citations (Scopus)

Downregulation of Par3 and aPKC function directs cells towards the ICM in the preimplantation mouse embryo

Plusa, B., Frankenberg, S., Chalmers, A., Hadjantonakis, A. K., Moore, C. A., Papalopulu, N., Papaioannou, V. E., Glover, D. M. & Zernicka-Goetz, M., 2005, In : Journal of Cell Science. 118, 3, p. 505-515 11 p.

Research output: Contribution to journalArticle

2003
89 Citations (Scopus)

Oriented cell divisions asymmetrically segregate aPKC and generate cell fate diversity in the early Xenopus embryo

Chalmers, A. D., Strauss, B. & Papalopulu, N., 2003, In : Development. 130, 12, p. 2657-2668 12 p.

Research output: Contribution to journalArticle

2002
73 Citations (Scopus)

Intrinsic differences between the superficial and deep layers of the Xenopus ectoderm control primary neuronal differentiation

Chalmers, A. D., Welchman, D. & Papalopulu, N., 2002, In : Developmental Cell. 2, 2, p. 171-182 12 p.

Research output: Contribution to journalArticle

2001

Primary neuronal differentiation and orientated cell division in Xenopus

Chalmers, A. D., Strauss, B. & Papalopulu, N., 2001, In : Developmental Biology. 235, 1, p. 216-216 1 p.

Research output: Contribution to journalArticle

2000
60 Citations (Scopus)

FGF-8 stimulates neuronal differentiation through FGFR-4a and interferes with mesoderm induction in Xenopus embryos

Hardcastle, Z., Chalmers, A. & Papalopulu, N., Nov 2000, In : Current Biology. 10, 23, p. 1511-1514 4 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Regional gene expression in the epithelia of the Xenopus tadpole gut

Chalmers, A., Slack, J. & Beck, C., Aug 2000, In : Mechanisms of Development. 96, 1, p. 125-128 4 p.

Research output: Contribution to journalArticle

Xenopus
Larva
Epithelium
Homeobox Genes
Gene Expression
99 Citations (Scopus)

The Xenopus Tadpole gut: fate maps and morphogenetic movements

Chalmers, A. & Slack, J., 15 Jan 2000, In : Development. 127, p. 381-392 12 p.

Research output: Contribution to journalArticle

Endoderm
Xenopus
Gastrula
Larva
Smooth Muscle
1998
78 Citations (Scopus)

Development of the gut in Xenopus laevis.

Chalmers, A. & Slack, J., Dec 1998, In : Developmental Dynamics. 212, 4, p. 509-521 13 p.

Research output: Contribution to journalArticle