• 4 SOUTH 0.44

Accepting Doctoral Students

19982018

Research output per year

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Personal profile

Research interests

Our research focuses on understanding the behaviour of epithelial cells in normal tissues and during tumour formation, with recent work focusing on examining the expression of stem cell regulators in prostate cancer.

I also have a strong interest in improving the use and reliability of research antibodies. I founded and am the Chief Scientific Officer of the spin out company CiteAb (www.citeab.com). CiteAb runs a citation based antibody search engine which aims to provide a better way for researchers to find antibodies which are suitable for their experiments. I have also contributed to a number of initiatives aimed at improving antibody validation, for example I am a founding guest editor of the F1000Research Antibody Validation Channel, which hosts a collection of primary papers, reviews and comment articles which focus on antibody validation.

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Projects

Research Output

Expression of SALL4 in prostate cancer

Chalmers, A. & Alghezi, D., 31 Jul 2018, In : Cancer Research. 78, 13 Supplement, 1 p., 2637.

Research output: Contribution to journalMeeting abstract

A subset of high Gleason grade prostate carcinomas contain a large burden of prostate cancer syndecan-1 positive stromal cells

Sharpe, B., Alghezi, D. A., Cattermole, C., Beresford, M., Bowen, R., Mitchard, J. & Chalmers, A. D., 15 Sep 2017, In : Prostate. 77, 13, p. 1312-1324 13 p., 23391.

Research output: Contribution to journalArticle

Open Access
File
  • 7 Citations (Scopus)
    35 Downloads (Pure)

    Cell surface dynamics and cellular distribution of endogenous FcRn

    D'Hooghe, L., D Chalmers, A., Heywood, S. & Whitley, P., 17 Aug 2017, In : PLoS ONE. 12, 8, e0182695.

    Research output: Contribution to journalArticle

    Open Access
  • 7 Citations (Scopus)

    Truncated RASSF7 promotes centrosomal defects and cell death

    Gulsen, T., Hadjicosti, I., Li, Y., Zhang, X., Whitley, P. R. & Chalmers, A. D., 15 Jan 2016, In : Developmental Biology. 409, 2, p. 502-517 16 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 2 Citations (Scopus)
    117 Downloads (Pure)

    Reproducibility: Standardize antibodies used in research

    Chalmers, A. & Bradbury, A., Feb 2015, In : Nature. 518, 7537, p. 27 - 29 3 p.

    Research output: Contribution to journalArticle

    295 Citations (Scopus)

    Thesis

    Cell fate specification and polarisation in mouse preimplantation epithelia

    Author: Doughton, G., 24 Jun 2014

    Supervisor: Chalmers, A. (Supervisor) & Welham, M. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File

    Characterisation of the imprinted genes in mouse: Grb10 and Dlk1

    Author: Madon, M., 30 Mar 2012

    Supervisor: Ward, A. (Supervisor) & Chalmers, A. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File

    Development of the first vertebrate epithelium

    Author: Wei, J., 1 Feb 2011

    Supervisor: Chalmers, A. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File

    Identifying potential new stem cell biomarkers for prostate cancer

    Author: Alghezi, D., 19 Jun 2019

    Supervisor: Chalmers, A. (Supervisor), Whitley, P. (Supervisor), Beresford, M. (External person) (Advisor), Bowen, R. (External person) (Advisor) & Mitchard, J. (External person) (Advisor)

    Student thesis: Doctoral ThesisPhD

    File

    Investigating the Role of the Mammalian RAS-Association Domain Family Member 7 (RASSF7)

    Author: Recino Scerif, A., 1 Feb 2011

    Supervisor: Chalmers, A. (Supervisor) & Ward, A. (Supervisor)

    Student thesis: Doctoral ThesisPhD

    File