• 7 WEST 2.10

Accepting PhD Students

19952019
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Research Output 1995 2019

2019

Film-forming agents as potential barriers to fungal skin infections

Ho, K. H., Delgado-Charro, B. & Bolhuis, A., 8 Apr 2019, In : Access Microbiology. 1

Research output: Contribution to journalMeeting abstract

Open Access

Inhibition of extracellular proteases improves the production of a xylanase in Parageobacillus thermoglucosidasius

Holland, A. T. N., Danson, M. J. & Bolhuis, A., 20 Mar 2019, In : BMC Biotechnology. 19, 1, 17.

Research output: Contribution to journalArticle

Open Access

Modelling biofilms on infected chronic wounds

Cheng, Y., De Bank, P. & Bolhuis, A., 8 Apr 2019, In : Access Microbiology. 1, 1A

Research output: Contribution to journalMeeting abstract

Open Access
6 Downloads (Pure)
Open Access
File
2018
2 Citations (Scopus)
22 Downloads (Pure)
Open Access
File
Amphotericin B
Bovine Serum Albumin
Critical Illness
Pharmaceutical Preparations
Health Services Needs and Demand
2017
9 Citations (Scopus)

Antibiofilm activity of α-mangostin extracted from Garcinia mangostana L. against Staphylococcus aureus

Nguyen, P. T. M., Quang, N. V., Mai, T. T., Kukukam, C., Reutrakul, V. & Bolhuis, A., Dec 2017, In : Asian Pacific Journal of Tropical Biomedicine. 10, 12, p. 1154-1160

Research output: Contribution to journalArticle

Open Access
Garcinia mangostana
Garcinia
Methicillin
Staphylococcus aureus
Biofilms
5 Citations (Scopus)
129 Downloads (Pure)

Anticaries and antimicrobial activities of methanolic extract from leaves of Cleistocalyx operculatus L.

Nguyen, P. T. M., Schultze, N., Boger, C., Alresley, Z., Bolhuis, A. & Lindequist, U., Jan 2017, In : Asian Pacific Journal of Tropical Biomedicine. 7, 1, p. 43-48

Research output: Contribution to journalArticle

Open Access
File
Syzygium
Bacteria
Streptococcus mutans
Biofilms
Flavonoids

Using a private social media platform with pharmacy students

Brown, K., Letchford, J. & Bolhuis, A., 2017, In : Pharmacy Education. 17, 1, p. 175-176 2 p.

Research output: Contribution to journalMeeting abstract

2016
1 Citation (Scopus)
115 Downloads (Pure)

Development of a filter to prevent infections with spore-forming bacteria in injecting drug users

Alhusein, N., Scott, J., Kasprzyk-Hordern, B. & Bolhuis, A., 1 Dec 2016, In : Harm Reduction Journal. 13, 1, 8 p., 33.

Research output: Contribution to journalArticle

Open Access
File
Heroin
Drug Users
Spores
Bacterial Spores
Bacteria
24 Citations (Scopus)
Zein
Biofilms
Tetracycline
Staphylococcus aureus
Skin

Investigating bottlenecks during protein secretion in Geobacillus thermoglucosidasisius

Holland, A., Danson, M. & Bolhuis, A., Nov 2016.

Research output: Contribution to conferencePoster

2015
8 Citations (Scopus)
105 Downloads (Pure)

Application of fluid dynamic gauging in the characterization and removal of biofouling deposits

Peck, O. P. W., Chew, Y. M. J., Bird, M. R. & Bolhuis, A., 2015, In : Heat Transfer Engineering. 36, 7-8, p. 685-694 10 p.

Research output: Contribution to journalArticle

Open Access
File
Biofouling
biofilms
Gaging
Biofilms
fluid dynamics
24 Citations (Scopus)
111 Downloads (Pure)

Low dietary iron intake restrains the intestinal inflammatory response and pathology of enteric infection by food-borne bacterial pathogens

Kortman, G. A. M., Mulder, M. L. M., Richters, T. J. W., Shanmugam, N. K. N., Trebicka, E., Boekhorst, J., Timmerman, H. M., Roelofs, R., Wiegerinck, E. T., Laarakkers, C. M., Swinkels, D. W., Bolhuis, A., Cherayil, B. J. & Tjalsma, H., Sep 2015, In : European Journal of Immunology. 45, 9, p. 2553-2567 13 p.

Research output: Contribution to journalArticle

File
Dietary Iron
Iron
Pathology
Food
Infection
2014

An assessment of the removal behaviour of biofilms grown under static and flow conditions

Peck, O., Chew, J., Bird, M. & Bolhuis, A., 2014, Fouling and Cleaning in Food Processing 2014: ‘Green Cleaning’.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

19 Citations (Scopus)
106 Downloads (Pure)

DNA as a target for antimicrobials

Bolhuis, A. & Aldrich-Wright, J. R., Aug 2014, In : Bioorganic Chemistry. 55, p. 51-59

Research output: Contribution to journalArticle

File
DNA
Infection
Anti-Bacterial Agents
Delivery of Health Care
39 Citations (Scopus)
61 Downloads (Pure)

The antimicrobial and antibiofilm activities of copper(II) complexes

Beeton, M., Aldrich-Wright, J. R. & Bolhuis, A., 1 Nov 2014, In : Journal of Inorganic Biochemistry. 140, p. 167-172 6 p.

Research output: Contribution to journalArticle

File
Biofilms
Copper
Methicillin
Staphylococcus aureus
Copper compounds
2013

Antibiotic Electrospun Micro/Nanofibrous Wound Dressing Formulations - In Vitro Testing Against Biofilms

Alhusein, N., De Bank, P., Blagbrough, I. & Bolhuis, A., Sep 2013, (Unpublished).

Research output: Contribution to conferencePoster

20 Citations (Scopus)
119 Downloads (Pure)
Open Access
File
Nanofibers
Biofilms
Tetracycline
Bacteria
Anti-Bacterial Agents
2012
15 Citations (Scopus)

Copper(ii) and palladium(ii) complexes with cytotoxic and antibacterial activity

Krause-Heuer, A. M., Leverett, P., Aldrich-Wright, J. R. & Bolhuis, A., 1 Jan 2012, In : Australian Journal of Chemistry. 65, 7, p. 860-873 14 p.

Research output: Contribution to journalArticle

Palladium
Copper
Cells
Cytotoxicity
Methylation
3 Citations (Scopus)
102 Downloads (Pure)

Mutations in the translation initiation region of the pac gene resulting in increased levels of activity of penicillin G acylase

Akkaya, Ö., İşsever Öztürk, S., Bolhuis, A. & Gümüşel, F., 2012, In : World Journal of Microbiology and Biotechnology. 28, 5, p. 2159-2164 6 p.

Research output: Contribution to journalArticle

Open Access
File
Penicillin Amidase
Mutation
Initiator Codon
Genes
Escherichia coli
135 Citations (Scopus)
104 Downloads (Pure)

Optically pure, water-stable metallo-helical ‘flexicate’ assemblies with antibiotic activity

Howson, S. E., Bolhuis, A., Brabec, V., Clarkson, G. J., Malina, J., Rodger, A. & Scott, P., Jan 2012, In : Nature Chemistry. 4, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Open Access
File
Antibiotics
Bacteria
Anti-Bacterial Agents
Methicillin
Enantiomers
2011
77 Citations (Scopus)
112 Downloads (Pure)

Antimicrobial activity of ruthenium-based intercalators

Bolhuis, A., Hand, L., Marshall, J. E., Richards, A. D., Rodger, A. & Aldrich-Wright, J., 18 Mar 2011, In : European Journal of Pharmaceutical Sciences. 42, 4, p. 313-317 5 p.

Research output: Contribution to journalArticle

Open Access
File
Intercalating Agents
Nematode Infections
Escherichia
Ruthenium
Poisons

Development of metal complexes as potential antimicrobials

Bolhuis, A. & Richards, A. D., 2011, Metallointercalators: Synthesis and Techniques to Probe Their Interactions with Biomolecules. Aldrich-Wright, J. (ed.). New York: Springer, p. 373-388 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

antibiotics
bacterium
metal
infectious disease
effect
5 Citations (Scopus)

Functional analysis of the sortase YhcS in Bacillus subtilis

Fasehee, H., Westers, H., Bolhuis, A., Antelmann, H., Hecker, M., Quax, W. J., Mirlohi, A. F., van Dijl, J. M. & Ahmadian, G., 2011, In : Proteomics. 11, 19, p. 3905-3913 9 p.

Research output: Contribution to journalArticle

Functional analysis
Bacilli
Bacillus subtilis
Cell Wall
Cells
97 Citations (Scopus)

Novel clues on the specific association of Streptococcus gallolyticus subsp gallolyticus with colorectal cancer

Boleij, A., Muytjens, C. M. J., Bukhari, S. I., Cayet, N., Glaser, P., Hermans, P. W. M., Swinkels, D. W., Bolhuis, A. & Tjalsma, H., 15 Apr 2011, In : Journal of Infectious Diseases. 203, 8, p. 1101-1109 9 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Biofilms
Bacteria
Collagen
Epithelium
2010
5 Citations (Scopus)

Analysis of the twin-arginine motif of a haloarchaeal Tat substrate

Kwan, D. & Bolhuis, A., Jul 2010, In : FEMS Microbiology Letters. 308, 2, p. 138-143 6 p.

Research output: Contribution to journalArticle

Arginine
Archaea
Consensus Sequence
Protein Sorting Signals
Computational Biology
2009
50 Citations (Scopus)

Antimicrobial activity of an iron triple helicate

Richards, A. D., Rodger, A., Hannon, M. J. & Bolhuis, A., May 2009, In : International Journal of Antimicrobial Agents. 33, 5, p. 469-472 4 p.

Research output: Contribution to journalArticle

Bacillus subtilis
Iron
Bacterial DNA
DNA
Microbial Drug Resistance

Enterococcal surface protein Esp affects antibiotic sensitivity in Enterococcus faecium

Meredith, K., Bolhuis, A. & O’Neill, M. A. A., 2009, In : International Journal of Antimicrobial Agents. 34, 4, p. 392-393 2 p.

Research output: Contribution to journalArticle

2008
8 Citations (Scopus)

Bioenergetic requirements of a Tat-dependent substrate in the halophilic archaeon Haloarcula hispanica

Kwan, D. C., Thomas, J. R. & Bolhuis, A., Dec 2008, In : FEBS Journal. 275, 24, p. 6159-6167 9 p.

Research output: Contribution to journalArticle

Haloarcula
Archaea
energy metabolism
arginine
proteins

Halophilic adaptation of proteins

Bolhuis, A., Kwan, D. & Thomas, J. R., 2008, Protein Adaptation in Extremophiles. Siddiqui, K. S. & Thomas, T. (eds.). New York: Nova Science Publishers, p. 71-104 34 p. (Molecular Anatomy and Physiology of Proteins ).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Halophilic adaptations of proteins

Bolhuis, A., Kwan, D. & Thomas, J. R., 2008, Protein Adaptation in Extremophiles: Design, Selection and Applications. Siddiqui, K. S., Thomas, T. & Uversky, V. (eds.). New York, U. S. A.: Nova Science Publishers, p. 71-104 (Molecular Anatomy and Physiology of Proteins).

Research output: Chapter in Book/Report/Conference proceedingChapter

salts
proteins
amino acid composition
salting
hydrophobicity
2006
21 Citations (Scopus)

The tatC gene cluster is essential for viability in halophilic archaea

Thomas, J. R. & Bolhuis, A., 2006, In : FEMS Microbiology Letters. 256, 1, p. 44-49 6 p.

Research output: Contribution to journalArticle

2005
75 Citations (Scopus)

Characterisation of a highly stable α-amylase from the halophilic archaeon Haloarcula hispanica

Hutcheon, G. W., Vasisht, N. & Bolhuis, A., 2005, In : Extremophiles. 9, p. 487-495 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

The core TatABC complex of the twin-arginine translocase in Escherichia coli : TatC drives assembly whereas TatA is essential for stability

Mangels, D., Mathers, J., Bolhuis, A. & Robinson, C., 2005, In : Journal of Molecular Biology. 345, p. 415-423 9 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

The twin-arginine translocation apparatus incorporates a distinct form of TatABC complex, spectrum of modular TatA complexes and minor TatAB complex

Oates, J., Barrett, C., Barnett, J., Byrne, K., Bolhuis, A. & Robinson, C., 2005, In : Journal of Molecular Biology. 346, 1, p. 295-305 11 p.

Research output: Contribution to journalArticle

Arginine
Gels
Thylakoids
Electrophoresis
Carrier Proteins
2004

Early transport: Protein secretion pathways in Archaea

Bolhuis, A., 2004, In : The Biochemist. 26, 3, p. 16-18 3 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)

Tat-dependent protein targeting in prokaryotes and chloroplasts

Robinson, C. & Bolhuis, A., 2004, In : Biochimica et Biophysica Acta. 1694, p. 135-147 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2003
62 Citations (Scopus)

Quantitative export of a reporter protein, GFP, by the twin-arginine translocation pathway in Escherichia coli

Barrett, C. M. L., Ray, N., Thomas, J. D., Robinson, C. & Bolhuis, A., 2003, In : Biochemical and Biophysical Research Communications. 304, 2, p. 279-284 6 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The archael twin-arginine translocation pathway

Hutcheon, G. W. & Bolhuis, A., 2003, In : Biochemical Society Transactions. 31, 3, p. 686-689 4 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)

YidC is strictly required for membrane insertion of subunits a and c of the F 1 F 0 ATP synthase and SecE of the SecYEG translocase

Yi, L., Jiang, F., Chen, M., Cain, B., Bolhuis, A. & Dalbey, R., 2003, In : Biochemistry. 42, p. 10537-10544 8 p.

Research output: Contribution to journalArticle

2002
66 Citations (Scopus)
67 Citations (Scopus)

The bdbDC operon of bacillus subtilis encodes thiol-disulfide oxidoreductases required for competence development

Meima, R., Eschevins, C., Fillinger, S., Bolhuis, A., Hamoen, L. W., Dorenbos, R., Quax, W. J., van Dijl, J. M., Provvedi, R., Chen, I., Dubnau, D. & Bron, S., 2002, In : Journal of Biological Chemistry. 277, 9, p. 6994-7001 8 p.

Research output: Contribution to journalArticle