Research Output 1970 2020

Article
12 Citations (Scopus)

14-amino, 14-alkylamino, and 14-acylamino analogs of oxymorphindole. Differential effects on opioid receptor binding and functional profiles

Grundt, P., Jales, A. R., Traynor, J. R., Lewis, J. W. & Husbands, S. M., 2003, In : Journal of Medicinal Chemistry. 46, p. 1563-1566 4 p.

Research output: Contribution to journalArticle

14N electric field gradient in trimethylamine complexes as a diagnostic for formation of ion pairs

Domene Nunez, C., Fowler, P. W. & Legon, A. C., 1 Aug 1999, In : Chemical Physics Letters. 309, 5-6, p. 463-470 8 p.

Research output: Contribution to journalArticle

Electric fields
Ions
gradients
electric fields
ions
5 Citations (Scopus)

14β-Arylpropiolylamino-17-cyclopropylmethyl-7,8-dihydronormorphinones and Related Opioids. Further Examples of Pseudoirreversible μ Opioid Receptor Antagonists

Nieland, N. P. R., Rennison, D., Broadbear, J. H., Purington, L., Woods, J. H., Traynor, J. R., Lewis, J. W. & Husbands, S. M., 2009, In : Journal of Medicinal Chemistry. 52, 21, p. 6926-6930 5 p.

Research output: Contribution to journalArticle

Narcotic Antagonists
mu Opioid Receptor
Opioid Analgesics
Ligands
6-codeinone
12 Citations (Scopus)

14β-O-cinnamoylnaltrexone and related dihydrocodeinones are mu opioid receptor partial agonists with predominant antagonist activity

Moynihan, H., Jales, A. R., Greedy, B. M., Rennison, D., Broadbear, J. H., Purington, L., Traynor, J. R., Woods, J. H., Lewis, J. W. & Husbands, S. M., 26 Mar 2009, In : Journal of Medicinal Chemistry. 52, 6, p. 1553-1557 5 p.

Research output: Contribution to journalArticle

Hydrocodone
mu Opioid Receptor
Naltrexone
Opioid Receptors
Esters
95 Citations (Scopus)

17β-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer

Day, J. M., Foster, P. A., Tutill, H. J., Parsons, M. F. C., Newman, S. P., Chander, S. K., Allan, G. M., Lawrence, H. R., Vicker, N., Potter, B. V. L., Reed, M. J. & Purohit, A., 2008, In : International Journal of Cancer. 122, 9, p. 1931-1940

Research output: Contribution to journalArticle

33 Citations (Scopus)

17β-hydroxysteroid dehydrogenase type 1 and type 2: association between mRNA expression and activity in cell lines

Day, J. M., Tutill, H. J., Newman, S. P., Purohit, A., Lawrence, H. R., Vicker, N., Potter, B. V. L. & Reed, M. J., 2006, In : Molecular and Cellular Endocrinology. 248, 1, p. 246-249

Research output: Contribution to journalArticle

3 Citations (Scopus)

19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids

Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

1-Bromopyrene

Taylor, R. E., Raithby, P. R. & Teat, S. J., 2006, In : Acta Crystallographica Section E-Structure Reports Online. 62, p. O1604-O1605

Research output: Contribution to journalArticle

Atoms
Molecules
organic compounds
Organic compounds
atoms
25 Citations (Scopus)

1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxicα,β-unsaturated aldehyde acrolein

Kelleher, M. O., McMahon, M., Eggleston, I. M., Dixon, M. J., Taguchi, K., Yamamoto, M. & Hayes, J. D., 2009, In : Carcinogenesis. 30, 10, p. 1754-1762 9 p.

Research output: Contribution to journalArticle

Acrolein
Aldehydes
NF-E2-Related Factor 2
Genes
Fibroblasts
4 Citations (Scopus)

1-D acoustic cavity in optical fibers using two acoustic Bragg gratings

Diez, A., Kakarantzas, G., Birks, T. A. & Russell, P. S., 2001, In : IEEE Photonics Technology Letters. 13, 9, p. 975-977 3 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
Engines
Exhaust gases
Turbines
Gases
Combustion knock

1-Ethyl-2-benzimidazolinone activates endothelial cell IKCa and smooth muscle hyperpolarization in rat isolated mesenteric artery

Walker, S. D., Dora, K. A., Ings, N. T., Crane, G. J. & Garland, C. J., 2002, In : British Journal of Pharmacology. 135, p. 25P

Research output: Contribution to journalArticle

6 Citations (Scopus)
110 Downloads (Pure)
Open Access
File
19 Citations (Scopus)

1H NMR studies on the reductively triggered release of heterocyclic and steroid drugs from 4,7-dioxoindole-3-methyl prodrugs

Ferrer, S., Naughton, D. P. & Threadgill, M. D., 2003, In : Tetrahedron. 59, 19, p. 3445-3454 10 p.

Research output: Contribution to journalArticle

1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues

Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

2,2'-Bipyridine-5-sulfonic acid

Burrows, A., Harrington, R. W. & Mahon, M., Nov 1999, In : Acta Crystallographica Section C-Crystal Structure Communications. 55, p. 1921-1924

Research output: Contribution to journalArticle

6 Citations (Scopus)

2,5-Bis(trimethylsilylethynyl)thieno[3,2-b]thiophene

Khan, M. S., Al-Naamani, R. S., Ahrens, B. & Raithby, P. R., 2004, In : Acta Crystallographica Section E-Structure Reports Online. 60, p. O1202-O1203

Research output: Contribution to journalArticle

Thiophenes
Thiophene
thiophenes
Polymers
Alkynes
3 Citations (Scopus)

2,6-bis(trimethylsilylethynyl)dithieno[3,2-b : 2 ',3 '-d]thiophene

Khan, M. S., Ahrens, B., Raithby, P. R. & Teat, S. J., 2004, In : Acta Crystallographica Section E-Structure Reports Online. 60, p. O1226-O1228

Research output: Contribution to journalArticle

Thiophenes
Thiophene
thiophenes
Polymers
polymers
2 Citations (Scopus)

2-[(E)-(5-Amino-2,3-diphenylquinoxalin-6-yl)iminomethyl]-4-bromophenol

Fun, H. K., Kia, R. & Raithby, P. R., 2008, In : Acta Crystallographica Section E-Structure Reports Online. 64, p. O1271-U1989

Research output: Contribution to journalArticle

Hydrogen bonds
Schiff Bases
Crystal structure
Ligands
Molecules

2010 Pharmaceutical Sciences World Congress Provides Dissolution Programming with an International Flavor

Martin, G. P., Fotaki, N., Salt, A. D. & Gray, V. A., May 2011, In : Dissolution Technologies. 18, 2, p. 38-42 5 p.

Research output: Contribution to journalArticle

Neurogenesis
Xenopus
Phosphotransferases
Cell Proliferation
Cell Polarity
3 Citations (Scopus)
102 Downloads (Pure)
Open Access
File
Energy harvesting
figure of merit
Ferroelectric materials
Anisotropy
Single crystals
5 Citations (Scopus)
31 Citations (Scopus)

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents

Leese, M. P., Newman, S. P., Purohit, A., Reed, M. J. & Potter, B. V. L., 2004, In : Bioorganic & Medicinal Chemistry Letters. 14, 12, p. 3135-3138 4 p.

Research output: Contribution to journalArticle

Steryl-Sulfatase
Estrone
Tumors
Estradiol
Estrogens
11 Citations (Scopus)

2-Amino-3,4-diethylpyrrole derivatives: New building blocks for coiled structures

Pantos, G. D., Rodriguez-Morgade, M. S., Torres, T., Lynch, V. M. & Sessler, J. L., 28 May 2006, In : Chemical Communications. 20, p. 2132-2134 3 p.

Research output: Contribution to journalArticle

Oligomers
Hydrogen bonds
Derivatives
76 Citations (Scopus)

2-aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo

Sekaran, S., Lall, G. S., Ralphs, K. L., Wolstenholme, A. J., Lucas, R. J., Foster, R. G. & Hankins, M. W., 2007, In : Journal of Neuroscience. 27, 15, p. 3981-3986 6 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Ion Channels
Transient Receptor Potential Channels
Pupil
Reflex
28 Citations (Scopus)

2'-Deoxy clyclic adenosine 5'-diphosphate ribose derivatives: importance of the 2'-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives

Zhang, B., Wagner, G. K., Weber, K., Garnham, C., Morgan, A. J., Galione, A., Guse, A. H. & Potter, B. V. L., 2008, In : Journal of Medicinal Chemistry. 51, 6, p. 1623-1636

Research output: Contribution to journalArticle

34 Citations (Scopus)

2-Difluoromethyloestrone 3-0-sulphamate, a highly potent steroid sulphatase inhibitor

Reed, J. E., Woo, L. W. L., Robinson, J. J., Leblond, B., Leese, M. P., Purohit, A., Reed, M. J. & Potter, B. V. L., 2004, In : Biochemical and Biophysical Research Communications. 317, 1, p. 169-175

Research output: Contribution to journalArticle

16 Citations (Scopus)

2 inhibitors of 11β-hydroxysteroid dehydrogenase type 1

Su, X., Vicker, N. & Potter, B. V. L., 2008, In : Progress in Medicinal Chemistry. 46, p. 29-130

Research output: Contribution to journalArticle

29 Citations (Scopus)

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique

Foster, P. A., Ho, Y. T., Newman, S. P., Kasprzyk, P. G., Leese, M. P., Potter, B. V. L., Reed, M. J. & Purohit, A., 2008, In : Breast Cancer Research and Treatment. 111, 2, p. 251-260

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Heterografts
Apoptosis
Breast Neoplasms
Neoplasms
26 Citations (Scopus)

2-MeOE2bisMATE induces caspase-dependent apoptosis in CAL51 breast cancer cells and overcomes resistance to TRAIL via cooperative activation of caspases

Wood, L., Leese, M. P., Mouzakiti, A., Purohit, A., Potter, B. V. L., Reed, M. J. & Packham, G., 2004, In : Apoptosis. 9, 3, p. 323-332

Research output: Contribution to journalArticle

29 Citations (Scopus)

2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer

Tagg, S. L. C., Foster, P. A., Leese, M. P., Potter, B. V. L., Reed, M. J., Purohit, A. & Newman, S. P., 2008, In : British Journal of Cancer. 99, 11, p. 1842-1848

Research output: Contribution to journalArticle

Deoxyglucose
Prostatic Neoplasms
Breast Neoplasms
Tumor Burden
Heterografts
19 Citations (Scopus)

2-Oxoacid dehydrogenase multienzyme complexes in the halophilic Archaea ? Gene sequences and protein structural predictions

Jolley, K. A., Maddocks, D. G., Gyles, S. L., Mullan, Z., Tang, S. L., Dyall-Smith, M. L., Hough, D. W. & Danson, M. J., 2000, In : Microbiology. 146, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

Multienzyme Complexes
Keto Acids
Dihydrolipoamide Dehydrogenase
Archaea
Pyruvate Dehydrogenase Complex
10 Citations (Scopus)

2-oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2

Domene, C., Abboud, M. I., McAllister, T. E., Leung, I. K. H., Chowdhury, R., Jorgensen, C., Mecinović, J., Lippl, K., Hancock, R. L., Hopkinson, R. J., Kawamura, A., Claridge, T. D. W. & Schofield, C. J., 28 Mar 2018, In : Chemical Communications. 54, 25, p. 3130-3133 4 p.

Research output: Contribution to journalArticle

Open Access
Prolyl Hydroxylases
Hydroxylation
Animals
Enzymes
Degradation
14 Citations (Scopus)

2-Position base-modified analogues of adenophostin A as high-affinity agonists of the D-myo-inositol trisphosphate receptor: in vitro evaluation and molecular modeling

Sureshan, K. M., Trusselle, M., Tovey, S. C., Taylor, C. W. & Potter, B. V. L., 2008, In : Journal of Organic Chemistry. 73, 5, p. 1682-1692

Research output: Contribution to journalArticle

87 Citations (Scopus)

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity

Leese, M. P., Leblond, B., Smith, A., Newman, S. P., Di Fiore, A., De Simone, G., Supuran, C. T., Purohit, A., Reed, M. J. & Potter, B. V. L., 2006, In : Journal of Medicinal Chemistry. 49, 26, p. 7683-7696

Research output: Contribution to journalArticle

21 Citations (Scopus)
128 Downloads (Pure)

2ʹ-Deoxyadenosine 5ʹ-diphosphoribose is an endogenous TRPM2 superagonist

Fliegert, R., Bauche, A., Wolf Pérez, A-M., Watt, J. M., Rozewitz, M. D., Winzer, R., Janus, M., Gu, F., Rosche, A., Harneit, A., Flato, M., Moreau, C., Kirchberger, T., Wolters, V., Potter, B. V. L. & Guse, A. H., 1 Sep 2017, In : Nature Chemical Biology. 13, p. 1036-1044 9 p.

Research output: Contribution to journalArticle

Open Access
File
Nicotinamide-Nucleotide Adenylyltransferase
Nicotinamide Mononucleotide
Adenosine Diphosphate Ribose
Glycoside Hydrolases
NAD
107 Citations (Scopus)

3,6-Disubstituted carbazole-based bisboronic acids with unusual fluorescence transduction as enantioselective fluorescent chemosensors for tartaric acid

Han, F., Chi, L., Liang, X., Ji, S., Liu, S., Zhou, F., Wu, Y., Han, K., Zhao, J. & James, T. D., 6 Feb 2009, In : Journal of Organic Chemistry. 74, 3, p. 1333-1336 4 p.

Research output: Contribution to journalArticle

Fluorescence
Acids
Enantiomers
Fluorophores
Sensors
2 Citations (Scopus)

3-(trimethylsilylethynyl)carbazole

Khan, M. S., Male, L., Raithby, P. R., Teat, S. J. & Bond, A. D., 2003, In : Acta Crystallographica Section E-Structure Reports Online. 59, p. O1342-O1344

Research output: Contribution to journalArticle

Alkynes
carbazoles
alkynes
Platinum
conjugation
13 Citations (Scopus)

3-Alkyl ethers of clocinnamox: Delayed long-term μ-antagonists with variable μ efficacy

Husbands, S. M., Sadd, J., Broadbear, J. H., Woods, J. H., Martin, J., Traynor, J. R., Aceto, M. D., Bowman, E. R., Harris, L. S. & Lewis, J. W., 1 Aug 1998, In : Journal of Medicinal Chemistry. 41, 18, p. 3493-3498 6 p.

Research output: Contribution to journalArticle

368 Citations (Scopus)

3D Computational Imaging with Single-Pixel Detectors

Sun, B., Edgar, M. P., Bowman, R., Vittert, L. E., Welsh, S., Bowman, A. & Padgett, M. J., 17 May 2013, In : Science. 340, 6134, p. 844-847 4 p.

Research output: Contribution to journalArticle

pixels
detectors
projectors
retrieval
illumination
15 Citations (Scopus)

3D cross-correlative matrix temperature detection and non-invasive thermal mapping based on a molecular probe

Guo, Y., Gu, S., Feng, X., Wang, J., Li, H., Han, T., Dong, Y., Jiang, X., James, T. D. & Wang, B., Nov 2014, In : Chemical Science. 5, 11, p. 4388-4393 6 p.

Research output: Contribution to journalArticle

Molecular Probes
Temperature
Fluorescence
Thermometers
Solvation
16 Citations (Scopus)

3-Deoxyclocinnamox: The first high-affinity, nonpeptide μ-opioid antagonist lacking a phenolic hydroxyl group

Derrick, I., Neilan, C. L., Andes, J., Husbands, S. M., Woods, J. H., Traynor, J. R. & Lewis, J. W., 1 Aug 2000, In : Journal of Medicinal Chemistry. 43, 17, p. 3348-3350 3 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

3D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification

Welten, M., Pavlovska, G., Chen, Y., Teruoka, Y., Fisher, M., Bangs, F., Towers, M. & Tickle, C., May 2011, In : Developmental Dynamics. 240, 5, p. 1278-1288 11 p.

Research output: Contribution to journalArticle

cdc Genes
Gene Expression
Genes
Hedgehogs
Optical Tomography
427 Citations (Scopus)
5 Downloads (Pure)

3D-HST+CANDELS: The Evolution of the Galaxy Size-Mass Distribution since z = 3

van der Wel, A., Franx, M., van Dokkum, P. G., Skelton, R. E., Momcheva, I. G., Whitaker, K. E., Brammer, G. B., Bell, E. F., Rix, H-W., Wuyts, S., Ferguson, H. C., Holden, B. P., Barro, G., Koekemoer, A. M., Chang, Y-Y., McGrath, E. J., Häussler, B., Dekel, A., Behroozi, P., Fumagalli, M. & 10 others, Leja, J., Lundgren, B. F., Maseda, M. V., Nelson, E. J., Wake, D. A., Patel, S. G., Labbé, I., Faber, S. M., Grogin, N. A. & Kocevski, D. D., 10 Jun 2014, In : Astrophysical Journal. 788, 1, 19 p.

Research output: Contribution to journalArticle

Open Access
File
mass distribution
galaxies
population type
stellar mass
distribution
283 Citations (Scopus)
80 Downloads (Pure)

3D-HST WFC3-selected Photometric Catalogs in the Five CANDELS/3D-HST Fields: Photometry, Photometric Redshifts, and Stellar Masses

Skelton, R. E., Whitaker, K. E., Momcheva, I. G., Brammer, G. B., van Dokkum, P. G., Labbé, I., Franx, M., van der Wel, A., Bezanson, R., Da Cunha, E., Fumagalli, M., Förster Schreiber, N., Kriek, M., Leja, J., Lundgren, B. F., Magee, D., Marchesini, D., Maseda, M. V., Nelson, E. J., Oesch, P. & 7 others, Pacifici, C., Patel, S. G., Price, S., Rix, H-W., Tal, T., Wake, D. A. & Wuyts, S., 1 Oct 2014, In : Astrophysical Journal Supplement. 214, 2, p. 24 1 p.

Research output: Contribution to journalArticle

Open Access
File
stellar mass
Hubble Space Telescope
catalogs
photometry
spectral energy distribution
1 Citation (Scopus)

3D Li Diffusion in c-LixTiS2 (x = 0.69 and 0.75): A Theoretical Study

Islam, M. M. & Bredow, T., 28 Sep 2015, In : Zeitschrift fur Physikalische Chemie. 229, 9, p. 1265-1274 10 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)

3D printed components with ultrasonically arranged microscale structure

Llewellyn-Jones, T. M., Drinkwater, B. W. & Trask, R. S., 18 Jan 2016, In : Smart Materials and Structures. 25, 2, 02LT01.

Research output: Contribution to journalArticle

microbalances
ultrasonics
Ultrasonics
glass fibers
printing