Department of Pharmacy & Pharmacology

Research Output 1978 2019

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Review article
2019

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review

Loisios-Konstantinidis, I., Paraiso, R. L. M., Fotaki, N., McAllister, M., Cristofoletti, R. & Dressman, J., 1 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 699-723 25 p.

Research output: Contribution to journalReview article

Open Access

Long Non-Coding RNAs and the Innate Immune Response

Hadjicharalambous, M. & Lindsay, M., 19 Apr 2019, In : Non-coding RNA. 5, 2, 34.

Research output: Contribution to journalReview article

Open Access

Non-Radiographic Axial Spondyloarthritis (nr-axSpA): Advances in Classification, Imaging and Therapy

Robinson, P. C., Sengupta, R. & Siebert, S., 20 Feb 2019, In : Rheumatology and therapy. 6, 2, p. 165-177 13 p.

Research output: Contribution to journalReview article

Open Access
2018
7 Citations (Scopus)

A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis: A GRAPPA-OMERACT initiative

Højgaard, P., Klokker, L., Orbai, A-M., Holmsted, K., Bartels, E. M., Leung, Y. Y., Goel, N., de Wit, M., Gladman, D. D., Mease, P. J., Dreyer, L., Kristensen, L. E., Fitzgerald, O., Tillett, W., Gossec, L., Helliwell, P., Strand, V., Ogdie, A., Terwee, C. B. & Christensen, R., 1 Apr 2018, In : Seminars in Arthritis and Rheumatism. 47, 5, p. 654-665 12 p.

Research output: Contribution to journalReview article

Open Access
File
Psoriatic Arthritis
Reproducibility of Results
Social Participation
Patient Reported Outcome Measures
Ankylosing Spondylitis
17 Citations (Scopus)

Autoantibodies in myositis

McHugh, N. J. & Tansley, S. L., 1 May 2018, In : Nature reviews. Rheumatology. 14, 5, p. 290-302 13 p.

Research output: Contribution to journalReview article

Open Access
Myositis
Autoantibodies
Autoantigens
Inborn Genetic Diseases
Disease Management

Chemical approaches for the enhancement of 5-aminolevulinic acid-based photodynamic therapy and photodiagnosis

Tewari, K. M. & Eggleston, I. M., 8 Oct 2018, In : Photochemical and Photobiological Sciences. 17, 11, p. 1553-1572 20 p.

Research output: Contribution to journalReview article

Open Access

Classification and Outcome Measures for Psoriatic Arthritis

Leung, Y. Y., Ogdie, A., Orbai, A-M., Tillett, W., Coates, L. C., Strand, V., Mease, P. & Gladman, D. D., 1 Oct 2018, In : Frontiers in Medicine. 5, 246.

Research output: Contribution to journalReview article

Open Access
File
Psoriatic Arthritis
Outcome Assessment (Health Care)
Psoriasis
Arthritis
Nails
5 Citations (Scopus)
Open Access
File
Microscopic Angioscopy
Systemic Scleroderma
Disease Progression
Ulcer
Calcinosis

Exploring the patient experience of digital ulcers in systemic sclerosis

Hughes, M. & Pauling, J. D., 11 Aug 2018, In : Seminars in Arthritis and Rheumatism.

Research output: Contribution to journalReview article

Systemic Scleroderma
Ulcer
Social Participation
Clinical Trials
Morbidity
6 Citations (Scopus)

Pharmacist services for non-hospitalised patients

de Barra, M., Scott, C. L., Scott, N. W., Johnston, M., de Bruin, M., Nkansah, N., Bond, C. M., Matheson, C. I., Rackow, P., Williams, A. J. & Watson, M. C., 4 Sep 2018, In : Cochrane Database of Systematic Reviews. 2018, 9, 224 p., CD013102.

Research output: Contribution to journalReview article

Pharmacists
Confidence Intervals
Odds Ratio
Meta-Analysis
Glycosylated Hemoglobin A

Systematic review: the consequences of psychosocial effects of inflammatory bowel disease on patients′ reproductive health

Purewal, S., Chapman, S., Czuber-Dochan, W., Selinger, C., Steed, H. & Brookes, M. J., 28 Nov 2018, In : Alimentary Pharmacology and Therapeutics. 48, 11-12, p. 1202-1212 11 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

VEGF (Vascular Endothelial Growth Factor) and Fibrotic Lung Disease

Barratt, S. L., Flower, V. A., Pauling, J. D. & Millar, A. B., 24 Apr 2018, In : International Journal of Molecular Sciences. 19, 5, 1269.

Research output: Contribution to journalReview article

Pulmonary diseases
lungs
Vascular Endothelial Growth Factor A
Lung Diseases
fibrosis
2017
6 Citations (Scopus)

An overview of pharmacodynamic modelling, ligand-binding approach and its application in clinical practice

Salahudeen, M. S. & Nishtala, P. S., 1 Feb 2017, In : Saudi Pharmaceutical Journal. 25, 2, p. 165-175 11 p.

Research output: Contribution to journalReview article

Open Access
Ligands
Pharmaceutical Preparations
Pharmacology
Sigmoid Colon
Binding Sites
1 Citation (Scopus)
Open Access
Raynaud Disease
Meta-Analysis
Peer Review
Psychological Stress
Headache
7 Citations (Scopus)

BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics

Hamilton, L., Barkham, N., Bhalla, A., Brittain, R., Cook, D., Jones, G., Mackay, K., Marshall, D., Marzo-Ortega, H., Murphy, D., Riddell, C., Sengupta, R., Siebert, S., Van Rossen, L., Gaffney, K. & BSR and BHPR Standards, Guidelines and Audit Working Group, Feb 2017, In : Rheumatology. 56, 2, p. 313-316 4 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Biological Products
Sacroiliac Joint
Guidelines
Iritis
7 Citations (Scopus)

Discontinuation of Preventive Medicines in Older People with Limited Life Expectancy: A Systematic Review

Narayan, S. W. & Nishtala, P. S., 1 Oct 2017, In : Drugs and Aging. 34, 10, p. 767-776 10 p.

Research output: Contribution to journalReview article

Preventive Medicine
Life Expectancy
Residential Facilities
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Health
6 Citations (Scopus)

Patient participation in patient-reported outcome instrument development in systemic sclerosis

Pauling, J. D., Frech, T. M., Domsic, R. & Hudson, M., 19 May 2017, In : Clinical and Experimental Rheumatology. 35 Suppl 106, 4, p. S184-S192 9 p.

Research output: Contribution to journalReview article

Open Access
Patient Participation
Systemic Scleroderma
Health Services Needs and Demand
Patient Reported Outcome Measures
Outcome Assessment (Health Care)
5 Citations (Scopus)

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

Leverment, S., Clarke, E., Wadeley, A. & Sengupta, R., Feb 2017, In : Rheumatology International. 37, 2, p. 257-271 15 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Sleep
Research
PubMed
Ethics
3 Citations (Scopus)

Should axial spondyloarthritis without radiographic changes be treated with anti-TNF agents?

Keat, A., Bennett, A. N., Gaffney, K., Marzo-Ortega, H., Sengupta, R. & Everiss, T., Mar 2017, In : Rheumatology International. 37, 3, p. 327-336 10 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Therapeutics
Sacroiliac Joint
Natural History
Consensus
2016
15 Citations (Scopus)

Anticholinergics: theoretical and clinical overview

Nishtala, P. S., Salahudeen, M. S. & Hilmer, S. N., 2 Jun 2016, In : Expert Opinion on Drug Safety. 15, 6, p. 753-768 16 p.

Research output: Contribution to journalReview article

Cholinergic Antagonists
Muscarinic Antagonists
Clinical Medicine
Expert Testimony
Therapeutic Uses

Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis

Grabski, M., Curran, H. V., Nutt, D. J., Husbands, S. M., Freeman, T. P., Fluharty, M. & Munafò, M. R., Dec 2016, In : Addiction. 111, 12, p. 2134-2144 11 p.

Research output: Contribution to journalReview article

Open Access
Smoking Cessation
Meta-Analysis
Confidence Intervals
Smoking
Task Performance and Analysis
27 Citations (Scopus)

Challenges and enablers of deprescribing: A general practitioner perspective

Ailabouni, N. J., Nishtala, P. S., Mangin, D. & Tordoff, J. M., 1 Apr 2016, In : PLoS ONE. 11, 4, 0151066.

Research output: Contribution to journalReview article

Open Access
general practitioners
General Practitioners
Medicine
interviews
Interviews
2015

Credentials for a PharmD graduate: The voyage never ends

Salahudeen, M. S. & Nishtala, P. S., 2015, In : Sage Open. 3, p. 2050312115584228

Research output: Contribution to journalReview article

Open Access
graduate
career advancement
professional career
educational opportunity
geriatrics
2014
14 Citations (Scopus)

Acute regulation of PDK1 by a complex interplay of molecular switches

Calleja, V., Laguerre, M., de Las Heras-Martinez, G., Parker, P. J., Requejo-Isidro, J. & Larijani, B., Oct 2014, In : Biochemical Society Transactions. 42, 5, p. 1435-40 6 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)

Effective use of transdermal drug delivery in children

Delgado-Charro, M. B. & Guy, R. H., 30 Jun 2014, In : Advanced Drug Delivery Reviews. 73, p. 63-82

Research output: Contribution to journalReview article

File
Pediatrics
Pharmaceutical Preparations
Skin
Cutaneous Administration
Transdermal Patch
26 Citations (Scopus)

Impact of anticholinergic discontinuation on cognitive outcomes in older people: A systematic review

Salahudeen, M. S., Duffull, S. B. & Nishtala, P. S., 1 Mar 2014, In : Drugs and Aging. 31, 3, p. 185-192 8 p.

Research output: Contribution to journalReview article

Cholinergic Antagonists
Length of Stay
Cohort Studies
Confusion
Institutionalization
18 Citations (Scopus)

Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Huang, R. M., Chen, Y. N., Zeng, Z., Gao, C. H., Su, X. & Peng, Y., 2 Dec 2014, In : Marine Drugs. 12, 12, p. 5817-5838 22 p.

Research output: Contribution to journalReview article

Open Access
Nucleosides
Nucleotides
Biological Phenomena
RNA
DNA
3 Citations (Scopus)

Principle of duality in phospholipids: regulators of membrane morphology and dynamics

Larijani, B., Hamati, F., Kundu, A., Chung, G. C., Domart, M-C., Collinson, L. & Poccia, D. L., Oct 2014, In : Biochemical Society Transactions. 42, 5, p. 1335-1342 8 p.

Research output: Contribution to journalReview article

2013
57 Citations (Scopus)

A radical sense of direction: signalling and mechanism in cryptochrome magnetoreception

Dodson, C. A., Hore, P. J. & Wallace, M. I., 1 Sep 2013, In : Trends in Biochemical Sciences. 38, 9, p. 435-446

Research output: Contribution to journalReview article

Cryptochromes
Birds
Biophysics
Flavoproteins
Magnetic Fields
11 Citations (Scopus)

Juvenile versus adult-onset ankylosing spondylitis -- clinical, radiographic, and social outcomes. a systematic review

Jadon, D. R., Ramanan, A. V. & Sengupta, R., Nov 2013, In : The Journal of Rheumatology. 40, 11, p. 1797-805 9 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Shoulder Joint
Hip Joint
Age of Onset
Ankle
22 Citations (Scopus)

Magnetic field effects in flavoproteins and related systems

Evans, E., Dodson, C., Maeda, K., Biskup, T., Wedge, C. & Timmel, C., 23 Aug 2013, In : Interface Focus. 3, 5

Research output: Contribution to journalReview article

Magnetic field effects
Flavoproteins
Magnetic Fields
Cryptochromes
Flavins
10 Citations (Scopus)

The structural mechanisms that underpin mitotic kinase activation

Dodson, C. A., Haq, T., Yeoh, S., Fry, A. M. & Bayliss, R., 18 Jul 2013, In : Biochemical Society Transactions. 41, 4, p. 1037-1041

Research output: Contribution to journalReview article

Phosphotransferases
Chemical activation
Phosphorylation
Conformations
Aurora Kinases
2012
26 Citations (Scopus)

Iontophoretic drug delivery across the nail

Delgado-Charro, M. B., Jan 2012, In : Expert Opinion on Drug Delivery. 9, 1, p. 91-103 13 p.

Research output: Contribution to journalReview article

Nails
Iontophoresis
Pharmaceutical Preparations
Onychomycosis
terbinafine
2011
212 Citations (Scopus)

Anticancer activity of metal complexes: involvement of redox processes

Jungwirth, U., Kowol, C. R., Keppler, B. K., Hartinger, C. G., Berger, W. & Heffeter, P., 15 Aug 2011, In : Antioxidants & Redox Signaling. 15, 4, p. 1085-127 43 p.

Research output: Contribution to journalReview article

Coordination Complexes
Oxidation-Reduction
Metals
Homeostasis
Copper
22 Citations (Scopus)

Practice-based pharmaceutical services: A systematic review

Fish, A., Watson, M. C. & Bond, C. M., 21 Feb 2011, In : International Journal of Pharmacy Practice. 10, 4, p. 225-233 9 p.

Research output: Contribution to journalReview article

2010
3 Citations (Scopus)
Raynaud Disease
Systemic Scleroderma
Blood Vessels
1 Citation (Scopus)

Other seronegative spondyloarthropathies

McHugh, N. J., 1 Apr 2010, In : Medicine. 38, 4, p. 190-193 4 p.

Research output: Contribution to journalReview article

Spondylarthropathies
HLA-B27 Antigen
Psoriatic Arthritis
Joints
Sacroiliitis
34 Citations (Scopus)

The role of scaffold proteins in JNK signalling

Engstrom, W., Ward, A. & Moorwood, K., Feb 2010, In : Cell Proliferation. 43, 1, p. 56-66 11 p.

Research output: Contribution to journalReview article

MAP Kinase Signaling System
Cell Cycle
Proteins
2009
12 Citations (Scopus)
Iontophoresis
Pharmaceutical Preparations
Drug Compounding
Skin Temperature
Drug Monitoring
2008
166 Citations (Scopus)

Resistance against novel anticancer metal compounds: differences and similarities

Heffeter, P., Jungwirth, U., Jakupec, M., Hartinger, C., Galanski, M., Elbling, L., Micksche, M., Keppler, B. & Berger, W., 9 Apr 2008, In : Drug Resistance Updates. 11, 1-2, p. 1-16 16 p.

Research output: Contribution to journalReview article

Metals
oxaliplatin
Drug Resistance
Platinum Compounds
Lanthanum
2007
39 Citations (Scopus)

Oral versus intra-vaginal imidazole and triazole anti-fungal treatment of uncomplicated vulvovaginal candidiasis (thrush)

Nurbhai, M., Grimshaw, J., Watson, M., Bond, C. M., Mollison, J. & Ludbrook, A., 17 Oct 2007, In : Cochrane Database of Systematic Reviews. 4, 57 p., CD002845.

Research output: Contribution to journalReview article

34 Citations (Scopus)

The assessment of ankylosing spondylitis in clinical practice

Sengupta, R. & Stone, M. A., Sep 2007, In : Nature Clinical Practice Rheumatology. 3, 9, p. 496-503 8 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Patient Selection
Tumor Necrosis Factor-alpha
Therapeutics
Back Pain
2006
72 Citations (Scopus)

A systematic review of the use of simulated patients and pharmacy practice research

Watson, M. C., Norris, P. & Granås, A. G., 1 Jun 2006, In : International Journal of Pharmacy Practice. 14, 2, p. 83-93 11 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Non-aspirin, non-steroidal anti-inflammatory drugs for treating osteoarthritis of the knee

Watson, M., T. Brookes, S., Faulkner, A. & J. Kirwan, J., 25 Jan 2006, In : The Cochrane Library. 3

Research output: Contribution to journalReview article

1 Citation (Scopus)

Other seronegative spondyloarthropathies

McHugh, N. J., 1 Oct 2006, In : Medicine. 34, 10, p. 401-404 4 p.

Research output: Contribution to journalReview article

Spondylarthropathies
HLA-B27 Antigen
Psoriatic Arthritis
Joints
Sacroiliitis
2 Citations (Scopus)

Recognising polymyalgia rheumatica

Sengupta, R. & Kyle, V., Nov 2006, In : The Practitioner. 250, 1688, p. 40-4, 47

Research output: Contribution to journalReview article

123 Citations (Scopus)

Systematic review of treatments for psoriatic arthritis: An evidence based approach and basis for treatment guidelines

Kavanaugh, A. F., Ritchlin, C. T., Boehncke, W. H., Cassell, S., Gladman, D. D., Gottlieb, A. B., Helliwell, P., Krueger, G., McHugh, N. J., Mease, P. J., Menon, K., Nash, P., Prinz, J., Rzany, B., Siu, K., Soriano, E. R. & Strober, B. E., 1 Jul 2006, In : Journal of Rheumatology. 33, 7, p. 1417-1421 5 p.

Research output: Contribution to journalReview article

Psoriatic Arthritis
Guidelines
Psoriasis
Therapeutics
Nails
2005
83 Citations (Scopus)

Noninvasive and minimally invasive methods for transdermal glucose monitoring

Sieg, A., Guy, R. H. & Delgado-Charro, M. B., 28 Feb 2005, In : Diabetes Technology & Therapeutics. 7, 1, p. 174-197 24 p.

Research output: Contribution to journalReview article