Department of Pharmacy & Pharmacology

Research Output 1978 2020

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Review article
2019

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review

Loisios-Konstantinidis, I., Paraiso, R. L. M., Fotaki, N., McAllister, M., Cristofoletti, R. & Dressman, J., 1 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 699-723 25 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
16 Downloads (Pure)
Open Access
File
Assisted Reproductive Techniques
Meta-Analysis
Life Style
Body Mass Index
Alcohol Drinking
Open Access
5 Citations (Scopus)
12 Downloads (Pure)

Botulinum and tetanus neurotoxins

Dong, M., Masuyer, G. & Stenmark, P., 20 Jun 2019, In : Annual Review of Biochemistry. 88, p. 811-837 27 p.

Research output: Contribution to journalReview article

Open Access
File
4 Downloads (Pure)

Effects of medicines used to treat gastrointestinal diseases on the pharmacokinetics of coadministered drugs: A PEARRL Review

Litou, C., Effinger, A., Kostewicz, E. S., Box, K. J., Fotaki, N. & Dressman, J. B., 1 Apr 2019, In : Pharmacy and Pharmacology Communications. 71, 4, p. 643-673 31 p.

Research output: Contribution to journalReview article

Open Access
File
Gastrointestinal Diseases
Pharmacokinetics
Pharmaceutical Preparations
Microbiota
Treatment Failure
2 Citations (Scopus)
3 Downloads (Pure)

Exploring the patient experience of digital ulcers in systemic sclerosis

Hughes, M. & Pauling, J. D., 1 Apr 2019, In : Seminars in Arthritis and Rheumatism. 48, 5, p. 888-894 7 p.

Research output: Contribution to journalReview article

Open Access
File
Systemic Scleroderma
Ulcer
Social Participation
Clinical Trials
Morbidity
4 Citations (Scopus)

Impact of Gastrointestinal Disease States on Oral Drug Absorption – implications for formulation design – a PEARRL review

Effinger, A., O'Driscoll, C. M., McAllister, M. & Fotaki, N., 1 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 674-698 25 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)

Long Non-Coding RNAs and the Innate Immune Response

Hadjicharalambous, M. & Lindsay, M., 19 Apr 2019, In : Non-coding RNA. 5, 2, 34.

Research output: Contribution to journalReview article

Open Access

Non-Radiographic Axial Spondyloarthritis (nr-axSpA): Advances in Classification, Imaging and Therapy

Robinson, P. C., Sengupta, R. & Siebert, S., 30 Jun 2019, In : Rheumatology and therapy. 6, 2, p. 165-177 13 p.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)
9 Citations (Scopus)
13 Downloads (Pure)

The patient experience of Raynaud's phenomenon in systemic sclerosis

Pauling, J. D., Saketkoo, L. A., Matucci-Cerinic, M., Ingegnoli, F. & Khanna, D., 1 Jan 2019, In : Rheumatology. 58, 1, p. 18-26 9 p., key026.

Research output: Contribution to journalReview article

Open Access
File
Raynaud Disease
Systemic Scleroderma
Social Participation
Body Image
Practice Management
43 Downloads (Pure)

The Role of Vascular Endothelial Growth Factor in Systemic Sclerosis

Flower, V. A., Barratt, S. L., Ward, S. & Pauling, J. D., 2019, In : Current Rheumatology Reviews. 15, 2, p. 99-109 11 p.

Research output: Contribution to journalReview article

Open Access
File
Systemic Scleroderma
Vascular Endothelial Growth Factor A
Protein Isoforms
Precision Medicine
Disease Management
2018
3 Citations (Scopus)

A scoping review of the pharmaceutical care needs of people with sensory loss

Killick, K., McAden, L., Smith, A., Kroll, T., Stoddart, K. & Watson, M., 1 Oct 2018, In : International Journal of Pharmacy Practice. 26, 5, p. 380-386 7 p.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)
20 Downloads (Pure)

A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis: A GRAPPA-OMERACT initiative

Højgaard, P., Klokker, L., Orbai, A-M., Holmsted, K., Bartels, E. M., Leung, Y. Y., Goel, N., de Wit, M., Gladman, D. D., Mease, P. J., Dreyer, L., Kristensen, L. E., Fitzgerald, O., Tillett, W., Gossec, L., Helliwell, P., Strand, V., Ogdie, A., Terwee, C. B. & Christensen, R., 1 Apr 2018, In : Seminars in Arthritis and Rheumatism. 47, 5, p. 654-665 12 p.

Research output: Contribution to journalReview article

Open Access
File
Psoriatic Arthritis
Reproducibility of Results
Social Participation
Patient Reported Outcome Measures
Ankylosing Spondylitis
28 Citations (Scopus)

Autoantibodies in myositis

McHugh, N. J. & Tansley, S. L., 1 May 2018, In : Nature reviews. Rheumatology. 14, 5, p. 290-302 13 p.

Research output: Contribution to journalReview article

Open Access
Myositis
Autoantibodies
Autoantigens
Inborn Genetic Diseases
Disease Management

Biologics for treating axial spondyloarthritis

Jones, A., Ciurtin, C., Ismajli, M., Leandro, M., Sengupta, R. & Machado, P. M., 2018, In : Expert Opinion on Biological Therapy. 18, 6, p. 641-652 12 p.

Research output: Contribution to journalReview article

Biosimilar Pharmaceuticals
Interleukin-17
Biological Products
Tumor Necrosis Factor-alpha
Janus Kinases
4 Citations (Scopus)

Chemical approaches for the enhancement of 5-aminolevulinic acid-based photodynamic therapy and photodiagnosis

Tewari, K. M. & Eggleston, I. M., 1 Nov 2018, In : Photochemical and Photobiological Sciences. 17, 11, p. 1553-1572 20 p.

Research output: Contribution to journalReview article

Open Access
8 Downloads (Pure)

Classification and Outcome Measures for Psoriatic Arthritis

Leung, Y. Y., Ogdie, A., Orbai, A-M., Tillett, W., Coates, L. C., Strand, V., Mease, P. & Gladman, D. D., 1 Oct 2018, In : Frontiers in Medicine. 5, 246.

Research output: Contribution to journalReview article

Open Access
File
Psoriatic Arthritis
Outcome Assessment (Health Care)
Psoriasis
Arthritis
Nails
10 Citations (Scopus)
8 Downloads (Pure)

Pharmacist services for non-hospitalised patients

de Barra, M., Scott, C. L., Scott, N. W., Johnston, M., de Bruin, M., Nkansah, N., Bond, C. M., Matheson, C. I., Rackow, P., Williams, A. J. & Watson, M. C., 4 Sep 2018, In : Cochrane Database of Systematic Reviews. 2018, 9, 224 p., CD013102.

Research output: Contribution to journalReview article

Open Access
File
Pharmacists
Confidence Intervals
Odds Ratio
Meta-Analysis
Glycosylated Hemoglobin A
11 Citations (Scopus)
1 Citation (Scopus)

Systematic review: the consequences of psychosocial effects of inflammatory bowel disease on patients′ reproductive health

Purewal, S., Chapman, S., Czuber-Dochan, W., Selinger, C., Steed, H. & Brookes, M. J., 28 Nov 2018, In : Alimentary Pharmacology and Therapeutics. 48, 11-12, p. 1202-1212 11 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
8 Downloads (Pure)
Open Access
File
Skin Manifestations
Systemic Scleroderma
Blood Vessels
Clinical Trials
Practice Guidelines
6 Citations (Scopus)

VEGF (Vascular Endothelial Growth Factor) and Fibrotic Lung Disease

Barratt, S. L., Flower, V. A., Pauling, J. D. & Millar, A. B., 24 Apr 2018, In : International Journal of Molecular Sciences. 19, 5, p. 1-17 17 p., 1269.

Research output: Contribution to journalReview article

Open Access
Pulmonary diseases
lungs
Vascular Endothelial Growth Factor A
Lung Diseases
fibrosis
2017
8 Citations (Scopus)

An overview of pharmacodynamic modelling, ligand-binding approach and its application in clinical practice

Salahudeen, M. S. & Nishtala, P. S., 1 Feb 2017, In : Saudi Pharmaceutical Journal. 25, 2, p. 165-175 11 p.

Research output: Contribution to journalReview article

Open Access
Ligands
Pharmaceutical Preparations
Pharmacology
Sigmoid Colon
Binding Sites
1 Citation (Scopus)
Open Access
Raynaud Disease
Meta-Analysis
Peer Review
Psychological Stress
Headache
7 Citations (Scopus)

BSR and BHPR guideline for the treatment of axial spondyloarthritis (including ankylosing spondylitis) with biologics

Hamilton, L., Barkham, N., Bhalla, A., Brittain, R., Cook, D., Jones, G., Mackay, K., Marshall, D., Marzo-Ortega, H., Murphy, D., Riddell, C., Sengupta, R., Siebert, S., Van Rossen, L., Gaffney, K. & BSR and BHPR Standards, Guidelines and Audit Working Group, Feb 2017, In : Rheumatology. 56, 2, p. 313-316 4 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Biological Products
Sacroiliac Joint
Guidelines
Iritis
9 Citations (Scopus)

Discontinuation of Preventive Medicines in Older People with Limited Life Expectancy: A Systematic Review

Narayan, S. W. & Nishtala, P. S., 1 Oct 2017, In : Drugs and Aging. 34, 10, p. 767-776 10 p.

Research output: Contribution to journalReview article

Preventive Medicine
Life Expectancy
Residential Facilities
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Health
7 Citations (Scopus)

Patient participation in patient-reported outcome instrument development in systemic sclerosis

Pauling, J. D., Frech, T. M., Domsic, R. & Hudson, M., 19 May 2017, In : Clinical and Experimental Rheumatology. 35 Suppl 106, 4, p. S184-S192 9 p.

Research output: Contribution to journalReview article

Open Access
Patient Participation
Systemic Scleroderma
Health Services Needs and Demand
Patient Reported Outcome Measures
Outcome Assessment (Health Care)
6 Citations (Scopus)

Prevalence and factors associated with disturbed sleep in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a systematic review

Leverment, S., Clarke, E., Wadeley, A. & Sengupta, R., Feb 2017, In : Rheumatology International. 37, 2, p. 257-271 15 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Sleep
Research
PubMed
Ethics
5 Citations (Scopus)

Should axial spondyloarthritis without radiographic changes be treated with anti-TNF agents?

Keat, A., Bennett, A. N., Gaffney, K., Marzo-Ortega, H., Sengupta, R. & Everiss, T., Mar 2017, In : Rheumatology International. 37, 3, p. 327-336 10 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Therapeutics
Sacroiliac Joint
Natural History
Consensus
2016
20 Citations (Scopus)

Anticholinergics: theoretical and clinical overview

Nishtala, P. S., Salahudeen, M. S. & Hilmer, S. N., 2 Jun 2016, In : Expert Opinion on Drug Safety. 15, 6, p. 753-768 16 p.

Research output: Contribution to journalReview article

Cholinergic Antagonists
Muscarinic Antagonists
Clinical Medicine
Expert Testimony
Therapeutic Uses

Behavioural tasks sensitive to acute abstinence and predictive of smoking cessation success: a systematic review and meta-analysis

Grabski, M., Curran, H. V., Nutt, D. J., Husbands, S. M., Freeman, T. P., Fluharty, M. & Munafò, M. R., Dec 2016, In : Addiction. 111, 12, p. 2134-2144 11 p.

Research output: Contribution to journalReview article

Open Access
Smoking Cessation
Meta-Analysis
Confidence Intervals
Smoking
Task Performance and Analysis
34 Citations (Scopus)

Challenges and enablers of deprescribing: A general practitioner perspective

Ailabouni, N. J., Nishtala, P. S., Mangin, D. & Tordoff, J. M., 1 Apr 2016, In : PLoS ONE. 11, 4, 0151066.

Research output: Contribution to journalReview article

Open Access
general practitioners
General Practitioners
Medicine
interviews
Interviews
2015

Credentials for a PharmD graduate: The voyage never ends

Salahudeen, M. S. & Nishtala, P. S., 2015, In : Sage Open. 3, p. 2050312115584228

Research output: Contribution to journalReview article

Open Access
graduate
career advancement
professional career
educational opportunity
geriatrics
26 Citations (Scopus)

Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Womens Health

Thomas, M. P. & Potter, B. V. L., 8 Oct 2015, In : Journal of Medicinal Chemistry. 58, 19, p. 7634-7658 25 p.

Research output: Contribution to journalReview article

2014
15 Citations (Scopus)

Acute regulation of PDK1 by a complex interplay of molecular switches

Calleja, V., Laguerre, M., de Las Heras-Martinez, G., Parker, P. J., Requejo-Isidro, J. & Larijani, B., Oct 2014, In : Biochemical Society Transactions. 42, 5, p. 1435-40 6 p.

Research output: Contribution to journalReview article

42 Citations (Scopus)
116 Downloads (Pure)

Effective use of transdermal drug delivery in children

Delgado-Charro, M. B. & Guy, R. H., 30 Jun 2014, In : Advanced Drug Delivery Reviews. 73, p. 63-82

Research output: Contribution to journalReview article

File
Pediatrics
Pharmaceutical Preparations
Skin
Cutaneous Administration
Transdermal Patch
27 Citations (Scopus)

Impact of anticholinergic discontinuation on cognitive outcomes in older people: A systematic review

Salahudeen, M. S., Duffull, S. B. & Nishtala, P. S., 1 Mar 2014, In : Drugs and Aging. 31, 3, p. 185-192 8 p.

Research output: Contribution to journalReview article

Cholinergic Antagonists
Length of Stay
Cohort Studies
Confusion
Institutionalization
18 Citations (Scopus)

Marine nucleosides: Structure, bioactivity, synthesis and biosynthesis

Huang, R. M., Chen, Y. N., Zeng, Z., Gao, C. H., Su, X. & Peng, Y., 2 Dec 2014, In : Marine Drugs. 12, 12, p. 5817-5838 22 p.

Research output: Contribution to journalReview article

Open Access
Nucleosides
Nucleotides
Biological Phenomena
RNA
DNA
3 Citations (Scopus)

Principle of duality in phospholipids: regulators of membrane morphology and dynamics

Larijani, B., Hamati, F., Kundu, A., Chung, G. C., Domart, M-C., Collinson, L. & Poccia, D. L., Oct 2014, In : Biochemical Society Transactions. 42, 5, p. 1335-1342 8 p.

Research output: Contribution to journalReview article

2013
64 Citations (Scopus)

A radical sense of direction: signalling and mechanism in cryptochrome magnetoreception

Dodson, C. A., Hore, P. J. & Wallace, M. I., 1 Sep 2013, In : Trends in Biochemical Sciences. 38, 9, p. 435-446

Research output: Contribution to journalReview article

Cryptochromes
Birds
Biophysics
Flavoproteins
Magnetic Fields
12 Citations (Scopus)

Juvenile versus adult-onset ankylosing spondylitis -- clinical, radiographic, and social outcomes. a systematic review

Jadon, D. R., Ramanan, A. V. & Sengupta, R., Nov 2013, In : The Journal of Rheumatology. 40, 11, p. 1797-805 9 p.

Research output: Contribution to journalReview article

Ankylosing Spondylitis
Shoulder Joint
Hip Joint
Age of Onset
Ankle
24 Citations (Scopus)

Magnetic field effects in flavoproteins and related systems

Evans, E., Dodson, C., Maeda, K., Biskup, T., Wedge, C. & Timmel, C., 23 Aug 2013, In : Interface Focus. 3, 5

Research output: Contribution to journalReview article

Magnetic field effects
Flavoproteins
Magnetic Fields
Cryptochromes
Flavins
11 Citations (Scopus)

The structural mechanisms that underpin mitotic kinase activation

Dodson, C. A., Haq, T., Yeoh, S., Fry, A. M. & Bayliss, R., 18 Jul 2013, In : Biochemical Society Transactions. 41, 4, p. 1037-1041

Research output: Contribution to journalReview article

Phosphotransferases
Chemical activation
Phosphorylation
Conformations
Aurora Kinases
2012
26 Citations (Scopus)

Iontophoretic drug delivery across the nail

Delgado-Charro, M. B., Jan 2012, In : Expert Opinion on Drug Delivery. 9, 1, p. 91-103 13 p.

Research output: Contribution to journalReview article

Nails
Iontophoresis
Pharmaceutical Preparations
Onychomycosis
terbinafine
2011
234 Citations (Scopus)

Anticancer activity of metal complexes: involvement of redox processes

Jungwirth, U., Kowol, C. R., Keppler, B. K., Hartinger, C. G., Berger, W. & Heffeter, P., 15 Aug 2011, In : Antioxidants & Redox Signaling. 15, 4, p. 1085-127 43 p.

Research output: Contribution to journalReview article

Coordination Complexes
Oxidation-Reduction
Metals
Homeostasis
Copper
22 Citations (Scopus)

Practice-based pharmaceutical services: A systematic review

Fish, A., Watson, M. C. & Bond, C. M., 21 Feb 2011, In : International Journal of Pharmacy Practice. 10, 4, p. 225-233 9 p.

Research output: Contribution to journalReview article

2010
3 Citations (Scopus)
Raynaud Disease
Systemic Scleroderma
Blood Vessels