Department of Pharmacy & Pharmacology

Research Output 1978 2020

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2019
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(Un)spoken realities of living with axial spondyloarthritis: a qualitative study focused on couple experiences

Raybone, K., Family, H., Sengupta, R. & Jordan, A., 3 Jul 2019, In : BMJ Open. 9, 7, p. 1-8 8 p., e025261.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids

Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.

Research output: Contribution to journalArticle

Open Access

1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues

Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Open Access
Open Access

A Complex Interplay of Anionic Phospholipid Binding Regulates 3′-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation

de Las Heras-Martinez, G., Calleja, V., Bailly, R., Dessolin, J., Larijani, B. & Requejo-Isidro, J., 10 Oct 2019, In : Scientific Reports. 9, 1, p. 1-18 18 p., 14527.

Research output: Contribution to journalArticle

Open Access

Amyloid peptide β 1-42 induces integrin α IIb β 3 activation, platelet adhesion, and thrombus formation in a NADPH Oxidase-Dependent Manner

Abubaker, A. A., Vara, D., Visconte, C., Eggleston, I., Torti, M., Canobbio, I. & Pula, G., 14 Mar 2019, In : Oxidative Medicine and Cellular Longevity. 2019, p. 1-12 12 p., 1050476.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access

A neurotoxin that specifically targets Anopheles mosquitoes

Contreras, E., Masuyer, G., Qureshi, N., Chawla, S., Dhillon, H. S., Lee, H. L., Chen, J., Stenmark, P. & Gill, S. S., 28 Jun 2019, In : Nature Communications. 10, 1, p. 1-10 10 p., 2869.

Research output: Contribution to journalArticle

Open Access

A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain

Conibear, A. E., Asghar, J., Hill, R., Henderson, G., Borbely, E., Tekus, V., Helyes, Z., Palandri, J., Bailey, C. P., Starke, I., von Mentzer, B., Kendall, D. & Kelly, E., 8 Oct 2019, In : Journal of Pharmacology and Experimental Therapeutics.

Research output: Contribution to journalArticle

A qualitative exploration of the experiences of community dwelling older adults with sensory impairment/s receiving polypharmacy on their pharmaceutical care journey

Smith, A., Macaden, L., Kroll, T., Alhusein, N., Taylor, A., Killick, K., Stoddart, K. & Watson, M., 1 Nov 2019, In : Age and Ageing. 48, 6, p. 895-902 8 p.

Research output: Contribution to journalArticle

Open Access

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(III)-based anion receptor

Hewitt, S., Ali, R., Mailhot, R., Antonen, C., Dodson, C. & Butler, S., 28 May 2019, In : Chemical Science. 10, 20, p. 5373-5381 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
6 Downloads (Pure)
Open Access
File

Association of Diverticulitis with Prolonged Spondyloarthritis: An Analysis of the ASAS-COMOSPA International Cohort

BRITSpA and the ASAS-COMOSPA Investigators, 26 Feb 2019, In : Journal of Clinical Medicine. 8, 3, 281.

Research output: Contribution to journalArticle

Open Access

A Threshold of Meaning for Work Disability Improvement in Psoriatic Arthritis Measured by the Work Productivity and Activity Impairment Questionnaire

Tillett, W., Lin, C-Y., Zbrozek, A., Sprabery, A. T. & Birt, J., 1 Sep 2019, In : Rheumatology and therapy. 6, 3, p. 379-391 13 p.

Research output: Contribution to journalArticle

Open Access

Biorelevant release testing of biodegradable microspheres intended for intra-articular administration

Magri, G., Selmin, F., Cilurzo, F. & Fotaki, N., 1 Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 115-122 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

BU10038 as a safe opioid analgesic with fewer side effects after systemic and intrathecal administration in primates

Kiguchi, N., Ding, H., Cami-Kobeci, G., Sukhtankar, D. D., Czoty, P. W., DeLoid, H. B., Hsu, F. -C., Toll, L., Husbands, S. & Ko, M. C., 1 Jun 2019, In : British Journal of Anaesthesia. 122, 6, p. e146-e156

Research output: Contribution to journalArticle

Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment

Monteiro, L. M., Löbenberg, R., Fotaki, N., Barros de Araujo, G. L., Cotrim, P. C. & Bou-Chacra, N. A., 1 Sep 2019, In : Journal of Global Antimicrobial Resistance. 18, p. 279-283 5 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, p. 1-5 5 p., 848.

Research output: Contribution to journalArticle

Open Access

Consumer internet purchasing of medicines using a population sample: A mixed methodology approach

Bowman, C., Family, H., Agius-Muscat, H., Cordina, M. & Sutton, J., 13 Sep 2019, In : Research in Social and Administrative Pharmacy. p. 1-9 9 p.

Research output: Contribution to journalArticle

Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin

Košenina, S., Masuyer, G., Zhang, S., Dong, M. & Stenmark, P., 1 Jun 2019, In : FEBS Letters. 593, 12, p. 1403-1410 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
4 Downloads (Pure)
Open Access
File
Geriatric Assessment
Dementia
Logistic Models
Potentially Inappropriate Medication List
Cholinergic Antagonists

Development of a peptide-based fluorescent probe for biological heme monitoring

Newton, L. D., Pascu, S. I., Tyrrell, R. M. & Eggleston, I. M., 21 Jan 2019, In : Organic and Biomolecular Chemistry. 17, 3, p. 467-471 5 p.

Research output: Contribution to journalArticle

Open Access

Diagnosis and initial management in psoriatic arthritis: a qualitative study with patients

Dures, E., Bowen, C., Brooke, M., Lord, J., Tillett, W., McHugh, N. & Hewlett, S., 26 Aug 2019, In : Rheumatology Advances in Practice. 3, 2, rkz022.

Research output: Contribution to journalArticle

Open Access
12 Downloads (Pure)

Did advice on the prescription of sodium valproate reduce prescriptions to women? An observational study in three European countries between 2007 and 2016

Charlton, R., Damase-Michel, C., Hurault-Delarue, C., Gini, R., Loane, M., Pierini, A., Puccini, A., Neville, A., Snowball, J., Morris, J. & EUROmediSAFE Consortium, O. B. O. T., 1 Nov 2019, In : Pharmacoepidemiology and Drug Safety. 28, 11, p. 1519-1528 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR

Kühn, F. J. P., Watt, J. M., Potter, B. V. L. & Lückhoff, A., 21 Mar 2019, In : Scientific Reports. 9, 1, p. 1-12 12 p., 4985.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
6 Downloads (Pure)

Drug burden index and its association with hip fracture among older adults: a national population-based study

Jamieson, H. A., Nishtala, P. S., Scrase, R., Deely, J. M., Abey-Nesbit, R., Hilmer, S. N., Abernethy, D. R., Berry, S. D., Mor, V., Lacey, C. J. & Schluter, P. J., 31 Jul 2019, In : J Gerontol A Biol Sci Med Sci. 74, 7, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

Open Access
File
Hip Fractures
Pharmaceutical Preparations
Population
Independent Living
Mortality
Open Access
2 Downloads (Pure)

Effect of filgotinib on health-related quality of life in active psoriatic arthritis: a randomized phase 2 trial (EQUATOR)

Orbai, A-M., Ogdie, A., Gossec, L., Tillett, W., Leung, Y. Y., Gao, J., Trivedi, M., Tasset, C., Meuleners, L., Besuyen, R., Hendrikx, T. & Coates, L. C., 18 Oct 2019, In : Rheumatology. kez408.

Research output: Contribution to journalArticle

Open Access
File
4 Downloads (Pure)

Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys

Flynn, S. M., Epperly, P. M., Davenport, A. T., Cami-Kobeci, G., Husbands, S. M., Ko, M. C. & Czoty, P. W., 10 Apr 2019, In : Neuropsychopharmacology. 44, 8, p. 1476-1484 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
11 Downloads (Pure)

Endorsement of the 66/68 joint count for the measurement of musculoskeletal disease activity: OMERACT 2018 Psoriatic Arthritis workshop report

Duarte-García, A., Leung, Y. Y., Coates, L. C., Beaton, D., Christensen, R., Craig, E. T., de Wit, M., Eder, L., Fallon, L., FitzGerald, O., Gladman, D. D., Goel, N., Holland, R., Lindsay, C., Maxwell, L., Mease, P., Orbai, A. M., Shea, B., Strand, V., Veale, D. J. & 2 others, Tillett, W. & Ogdie, A., 1 Aug 2019, In : The Journal of Rheumatology. 46, 8, p. 996-1005 10 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models

Elliott, M., Favre-Guilmard, C., Liu, S. M., Maignel, J., Masuyer, G., Beard, M., Boone, C., Carré, D., Kalinichev, M., Lezmi, S., Mir, I., Nicoleau, C., Palan, S., Perier, C., Raban, E., Zhang, S., Dong, M., Stenmark, P. & Krupp, J., 16 Jan 2019, In : Science Advances. 5, 1, p. 1-13 13 p., eaau7196.

Research output: Contribution to journalArticle

Open Access

EULAR points to consider for the development, evaluation and implementation of mobile health applications aiding self-management in people living with rheumatic and musculoskeletal diseases

Najm, A., Nikiphorou, E., Kostine, M., Richez, C., Pauling, J. D., Finckh, A., Ritschl, V., Prior, Y., Balážová, P., Stones, S., Szekanecz, Z., Iagnocco, A., Ramiro, S., Sivera, F., Dougados, M., Carmona, L., Burmester, G., Wiek, DI., Gossec, L. & Berenbaum, F., 13 Sep 2019, In : RMD Open. 5, 2, p. 1-7 7 p., e001014.

Research output: Contribution to journalArticle

Open Access

Evaluation of the Economic Burden of Psoriatic Arthritis and the Relationship Between Functional Status and Healthcare Costs

McHugh, N., Maguire, Á., Handel, I., Tillett, W., Morris, J., Hawkins, N., Cavill, C., Korendowych, E. & Mughal, F., 31 Aug 2019, In : The Journal of Rheumatology. 46, 8, 190083.

Research output: Contribution to journalArticle

2 Citations (Scopus)
12 Downloads (Pure)
Open Access
File
Raynaud Disease
Systemic Scleroderma
Physicians
Health
Color
12 Downloads (Pure)

Examining the Risks of Major Bleeding Events in Older People Using Antithrombotics

Nishtala, P., 1 Jun 2019, In : Cardiovascular Drugs and Therapy. 33, 3, p. 323-329 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
12 Downloads (Pure)

Expression of Myxovirus-resistance Protein A: A Possible Marker of Muscle Disease Activity and Autoantibody Specificities in Juvenile Dermatomyositis

Soponkanaporn, S., Deakin, C. T., Schutz, P. W., Marshall, L. R., Yasin, S. A., Johnson, C. M., Sag, E., Tansley, S. L., McHugh, N. J., Wedderburn, L. R. & Jacques, T. S., 1 Jun 2019, In : Neuropathology and Applied Neurobiology. 45, 4, p. 410-420 11 p.

Research output: Contribution to journalArticle

Open Access
Myxovirus Resistance Proteins
Staphylococcal Protein A
Autoantibodies
Myositis
Muscles
3 Citations (Scopus)
Open Access
Heroin
Sexually Transmitted Diseases
HIV
Viruses
Publications
3 Citations (Scopus)

Factors influencing Raynaud condition score diary outcomes in systemic sclerosis

Pauling, J. D., Reilly, E., Smith, T. & Frech, T. M., 1 Oct 2019, In : The Journal of Rheumatology. 46, 10, p. 1326-1334 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study

UK Primary Sjögren’s Syndrome registry, 1 Nov 2019, In : Rheumatology International. 39, 11, p. 1867-1873 7 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Myositis Genetics Consortium (MYOGEN), 1 Jul 2019, In : Annals of the Rheumatic Diseases. 78, 7, p. 996-1002 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge, Z., Tansley, S., Shaddick, G., Chinoy, H., Cooper, R. G., New, R. P., Lilleker, J. B., Vencovsky, J., Chazarain, L., Danko, K., Nagy-Vincze, M., Bodoki, L., Dastmalchi, M., Ekholm, L., Lundberg, I. E. & McHugh, N., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

The European Vasculitis Genetics Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 5120.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Higher education outreach: examining key challenges for academics

Johnson, M., Danvers, E., Hinton-Smith, T., Atkinson, K., Bowden, G., Foster, J., Garner, K., Garrud, P., Greaves, S., Harris, P., Hejmadi, M., Hill, D., Hughes, G., Jackson, L., O’Sullivan, A., ÓTuama, S., Perez Brown, P., Philipson, P., Ravenscroft, S., Rhys, M. & 6 others, Ritchie, T., Talbot, J., Walker, D., Watson, J., Williams, M. & Williams, S., 4 Feb 2019, In : British Journal of Educational Studies. 67, 4, p. 469-491 23 p.

Research output: Contribution to journalArticle

Highlights from the 2018 pharm sci AAPS annual meeting in Washington DC

Fotaki, N., Krämer, J. & Diaz, D., 1 Nov 2019, In : Dissolution Technologies. 26, 4, p. 38-45 8 p.

Research output: Contribution to journalArticle