Department of Pharmacy & Pharmacology

Research Output 1978 2020

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2019
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(Un)spoken realities of living with axial spondyloarthritis: a qualitative study focused on couple experiences

Raybone, K., Family, H., Sengupta, R. & Jordan, A., 3 Jul 2019, In : BMJ Open. 9, 7, e025261.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids

Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 1 May 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.

Research output: Contribution to journalArticle

Open Access

1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues

Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Open Access

Amyloid peptide β 1-42 induces integrin α IIb β 3 activation, platelet adhesion, and thrombus formation in a NADPH Oxidase-Dependent Manner

Abubaker, A. A., Vara, D., Visconte, C., Eggleston, I., Torti, M., Canobbio, I. & Pula, G., 14 Mar 2019, In : Oxidative Medicine and Cellular Longevity. 2019, 12 p., 1050476.

Research output: Contribution to journalArticle

Open Access
Open Access

A neurotoxin that specifically targets Anopheles mosquitoes

Contreras, E., Masuyer, G., Qureshi, N., Chawla, S., Dhillon, H. S., Lee, H. L., Chen, J., Stenmark, P. & Gill, S. S., 28 Jun 2019, In : Nature Communications. 10, 1, p. 1-10 10 p., 2869.

Research output: Contribution to journalArticle

Open Access

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(III)-based anion receptor

Hewitt, S., Ali, R., Mailhot, R., Antonen, C., Dodson, C. & Butler, S., 28 May 2019, In : Chemical Science. 10, 20, p. 5373-5381 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
1 Downloads (Pure)
Open Access
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Association of Diverticulitis with Prolonged Spondyloarthritis: An Analysis of the ASAS-COMOSPA International Cohort

BRITSpA and the ASAS-COMOSPA Investigators, 26 Feb 2019, In : Journal of Clinical Medicine. 8, 3, 281.

Research output: Contribution to journalArticle

Open Access

A Threshold of Meaning for Work Disability Improvement in Psoriatic Arthritis Measured by the Work Productivity and Activity Impairment Questionnaire

Tillett, W., Lin, C-Y., Zbrozek, A., Sprabery, A. T. & Birt, J., 1 Jun 2019, In : Rheumatology and therapy. p. 1-13

Research output: Contribution to journalArticle

Open Access

Biorelevant release testing of biodegradable microspheres intended for intra-articular administration

Magri, G., Selmin, F., Cilurzo, F. & Fotaki, N., 1 Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 115-122 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

BU10038 as a safe opioid analgesic with fewer side effects after systemic and intrathecal administration in primates

Kiguchi, N., Ding, H., Cami-Kobeci, G., Sukhtankar, D. D., Czoty, P. W., DeLoid, H. B., Hsu, F. -C., Toll, L., Husbands, S. & Ko, M. C., 1 Mar 2019, In : British Journal of Anaesthesia.

Research output: Contribution to journalArticle

Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment

Monteiro, L. M., Löbenberg, R., Fotaki, N., Barros de Araujo, G. L., Cotrim, P. C. & Bou-Chacra, N. A., 1 Sep 2019, In : Journal of Global Antimicrobial Resistance. 18, p. 279-283 5 p.

Research output: Contribution to journalArticle

Community pharmacists' role in preventing Opioid Substitution Therapy-related deaths: a qualitative investigation into current UK practice

Scott, J., Yadav, R., Taylor, D. & Taylor, G., 15 Feb 2019, In : International Journal of Clinical Pharmacy. 41, 2, p. 470-477 8 p., IJCP-D-17-00681R4.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, 848.

Research output: Contribution to journalArticle

Open Access

Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin

Košenina, S., Masuyer, G., Zhang, S., Dong, M. & Stenmark, P., 1 Jun 2019, In : FEBS Letters. 593, 12, p. 1403-1410 8 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Development of a peptide-based fluorescent probe for biological heme monitoring

Newton, L. D., Pascu, S. I., Tyrrell, R. M. & Eggleston, I. M., 21 Jan 2019, In : Organic and Biomolecular Chemistry. 17, 3, p. 467-471 5 p.

Research output: Contribution to journalArticle

Open Access

Diagnosis and initial management in psoriatic arthritis: a qualitative study with patients

Dures, E., Bowen, C., Brooke, M., Lord, J., Tillett, W., McHugh, N. & Hewlett, S., 26 Aug 2019, In : Rheumatology Advances in Practice. 3, 2, rkz022.

Research output: Contribution to journalArticle

Open Access
7 Downloads (Pure)

Did advice on the prescription of sodium valproate reduce prescriptions to women? An observational study in three European countries between 2007 and 2016

Charlton, R., Damase-Michel, C., Hurault-Delarue, C., Gini, R., Loane, M., Pierini, A., Puccini, A., Neville, A., Snowball, J., Morris, J. & EUROmediSAFE Consortium, O. B. O. T., 26 Aug 2019, In : Pharmacoepidemiology and Drug Safety.

Research output: Contribution to journalArticle

Open Access
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1 Citation (Scopus)

Different substrate specificities of the two ADPR binding sites in TRPM2 channels of Nematostella vectensis and the role of IDPR

Kühn, F. J. P., Watt, J. M., Potter, B. V. L. & Lückhoff, A., 21 Mar 2019, In : Scientific Reports. 9, 1, 4985.

Research output: Contribution to journalArticle

Open Access
2 Downloads (Pure)

Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys

Flynn, S. M., Epperly, P. M., Davenport, A. T., Cami-Kobeci, G., Husbands, S. M., Ko, M. C. & Czoty, P. W., 10 Apr 2019, In : Neuropsychopharmacology. 2019, 9 p.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
6 Downloads (Pure)

Endorsement of the 66/68 joint count for the measurement of musculoskeletal disease activity: OMERACT 2018 Psoriatic Arthritis workshop report

Duarte-García, A., Leung, Y. Y., Coates, L. C., Beaton, D., Christensen, R., Craig, E. T., de Wit, M., Eder, L., Fallon, L., FitzGerald, O., Gladman, D. D., Goel, N., Holland, R., Lindsay, C., Maxwell, L., Mease, P., Orbai, A. M., Shea, B., Strand, V., Veale, D. J. & 2 others, Tillett, W. & Ogdie, A., 15 Feb 2019, In : The Journal of Rheumatology.

Research output: Contribution to journalArticle

Open Access
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Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models

Elliott, M., Favre-Guilmard, C., Liu, S. M., Maignel, J., Masuyer, G., Beard, M., Boone, C., Carré, D., Kalinichev, M., Lezmi, S., Mir, I., Nicoleau, C., Palan, S., Perier, C., Raban, E., Zhang, S., Dong, M., Stenmark, P. & Krupp, J., 16 Jan 2019, In : Science Advances. 5, 1, p. 1-13 13 p., eaau7196.

Research output: Contribution to journalArticle

Open Access

Evaluation of the Economic Burden of Psoriatic Arthritis and the Relationship Between Functional Status and Healthcare Costs

McHugh, N., Maguire, Á., Handel, I., Tillett, W., Morris, J., Hawkins, N., Cavill, C., Korendowych, E. & Mughal, F., 31 Aug 2019, In : The Journal of Rheumatology. 46, 8, 190083.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1 Downloads (Pure)
Open Access
File
Raynaud Disease
Systemic Scleroderma
Physicians
Health
Color
12 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
11 Downloads (Pure)

Expression of Myxovirus-resistance Protein A: A Possible Marker of Muscle Disease Activity and Autoantibody Specificities in Juvenile Dermatomyositis

Soponkanaporn, S., Deakin, C. T., Schutz, P. W., Marshall, L. R., Yasin, S. A., Johnson, C. M., Sag, E., Tansley, S. L., McHugh, N. J., Wedderburn, L. R. & Jacques, T. S., 30 Jun 2019, In : Neuropathology and Applied Neurobiology. 45, 4, p. 410-420

Research output: Contribution to journalArticle

Open Access
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Myxovirus Resistance Proteins
Staphylococcal Protein A
Autoantibodies
Myositis
Muscles
2 Citations (Scopus)
Open Access
Heroin
Sexually Transmitted Diseases
HIV
Viruses
Publications

Factors influencing Raynaud’s condition score diary outcomes in systemic sclerosis.

Pauling, J. D., Reilly, E., Smith, T. & Frech, T. M., 1 Sep 2019, In : The Journal of Rheumatology. 46, 9, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study

UK Primary Sjögren’s Syndrome registry, 27 Jun 2019, In : Rheumatology International. p. 1-7 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Myositis Genetics Consortium (MYOGEN), 1 Jul 2019, In : Annals of the Rheumatic Diseases. 78, 7, p. 996-1002 7 p.

Research output: Contribution to journalArticle

Open Access

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge, Z., Tansley, S., Shaddick, G., Chinoy, H., Cooper, R. G., New, R. P., Lilleker, J. B., Vencovsky, J., Chazarain, L., Danko, K., Nagy-Vincze, M., Bodoki, L., Dastmalchi, M., Ekholm, L., Lundberg, I. E. & McHugh, N., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Higher education outreach: examining key challenges for academics

Johnson, M., Danvers, E., Hinton-Smith, T., Atkinson, K., Bowden, G., Foster, J., Garner, K., Garrud, P., Greaves, S., Harris, P., Hejmadi, M., Hill, D., Hughes, G., Jackson, L., O’Sullivan, A., ÓTuama, S., Perez Brown, P., Philipson, P., Ravenscroft, S., Rhys, M. & 6 others, Ritchie, T., Talbot, J., Walker, D., Watson, J., Williams, M. & Williams, S., 4 Feb 2019, In : British Journal of Educational Studies.

Research output: Contribution to journalArticle

Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling

de Cássia Zaghi Compri, J., Andres Felli, V. M., Lourenço, F. R., Takatsuka, T., Fotaki, N., Löbenberg, R., Bou-Chacra, N. A. & Barros de Araujo, G. L., 1 May 2019, In : Journal of Pharmaceutical Sciences. p. 1848-1856

Research output: Contribution to journalArticle

How does the public conceptualise the quality of care and its measurement in community pharmacies in the UK: A qualitative interview study

Watson, M., Silver, K. & Watkins, R., 1 Mar 2019, In : BMJ Open. 9, 3, p. 1-7 7 p., e027198.

Research output: Contribution to journalArticle

Open Access

Identification of novel small-molecule inhibitors of α-methylacyl-CoA racemase (AMACR; P504S) and structure-activity relationships

Petrova, Y., Wadda, K., Nathubhai, A., Jevglevskis, M., Mitchell, P., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 7 Sep 2019, In : Bioorganic Chemistry. 92, 103264.

Research output: Contribution to journalArticle

Increased Risk of Hypertension Associated with Spondyloarthritis Disease Duration: Results from the ASAS-COMOSPA Study

BRITSpA and COMOSPA Investigators, 31 Jan 2019, In : The Journal of Rheumatology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Influence of Aromatic Structure on the Thermal Behaviour of Lignin

Rowlandson, J. L., Woodman, T. J., Tennison, S. R., Edler, K. J. & P. Ting, V., 16 Jan 2019, In : Waste and Biomass Valorization.

Research output: Contribution to journalArticle

2 Citations (Scopus)
21 Downloads (Pure)
Open Access
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AMPA Receptors
Nicotinic Receptors
Morphine
Hippocampus
Recurrence

Inhibition of extracellular proteases improves the production of a xylanase in Parageobacillus thermoglucosidasius

Holland, A. T. N., Danson, M. J. & Bolhuis, A., 20 Mar 2019, In : BMC Biotechnology. 19, 1, 17.

Research output: Contribution to journalArticle

Open Access

In vitro–in vivo correlations based on in vitro dissolution of parent drug diltiazem and pharmacokinetics of its metabolite

Mircioiu, C., Anuta, V., Mircioiu, I., Nicolescu, A. & Fotaki, N., 16 Jul 2019, In : Pharmaceutics. 11, 7, 344.

Research output: Contribution to journalArticle

Open Access

Ketamine increases proliferation of human iPSC-derived neuronal progenitor cells via insulin-like growth factor 2 and independent of the NMDA receptor

Grossert, A., Mehrjardi, N. Z., Bailey, S., Lindsay, M., Hescheler, J., Saric, T. & Teusch, N., 24 Sep 2019, In : Cells. 8, 10, 1139.

Research output: Contribution to journalArticle

Open Access
16 Downloads (Pure)

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation

Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In : Chemical Science. 10, 14, p. 4069-4076 8 p.

Research output: Contribution to journalArticle

Open Access