Department of Biology & Biochemistry

Research Output 1970 2019

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Review article
2019

A century of bias in genetics and evolution

Hurst, L., 12 Jun 2019, In : Heredity. 123, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Being in a loop: how long non-coding RNAs organise genome architecture

Pisignano, G., Pavlaki, I. & Murrell, A., 9 Apr 2019, In : Essays in Biochemistry. 63, 1, p. 177-186 10 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
14 Downloads (Pure)

Cooking up the perfect insect: Aristotle's transformational idea about the complete metamorphosis of insects

Reynolds, S., 23 Aug 2019, In : Philosophical transactions B: Biological Sciences. 374, 1783, p. 1-16 16 p., 20190074.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)

Medium Chain Carboxylic Acids from Complex Organic Feedstocks by Mixed Culture Fermentation

De Groof, V., Coma, M., Arnot, T., Leak, D. J. & Lanham, A. B., 22 Jan 2019, In : Molecules. 24, 3, p. 1-32 32 p., 398.

Research output: Contribution to journalReview article

Open Access

Novel Agents in Heavily Pretreated Metastatic Gastric Cancer: More Shadows Than Lights

Roviello, G., D'Angelo, A., Roudi, R., Petrioli, R. & Mini, E., 4 Jul 2019, In : Journal of oncology. 2019, 9 p., 5692317.

Research output: Contribution to journalReview article

Open Access

Sex ratios and bimaturism differ between temperature-dependent and genetic sex-determination systems in reptiles

Bókony, V., Milne, G., Pipoly, I., Székely, T. & Liker, A., 18 Feb 2019, In : BMC Evolutionary Biology. 19, 1, p. 57 57.

Research output: Contribution to journalReview article

Open Access

The emperor penguin - Vulnerable to projected rates of warming and sea ice loss

Trathan, P. N., Wienecke, B., Barbraud, C., Jenouvrier, S., Kooyman, G., Le Bohec, C., Ainley, D. G., Ancel, A., Zitterbart, D. P., Chown, S. L., Larue, M., Cristofari, R., Younger, J., Clucas, G., Bost, C., Brown, J. A., Gillett, H. J. & Fretwell, P. T., 8 Oct 2019, In : Biological Conservation. 108216.

Research output: Contribution to journalReview article

Open Access

The hijackers guide to escaping complement: Lessons learned from pathogens

Ermert, D., Ram, S. & Laabei, M., 1 Oct 2019, In : Molecular Immunology. 114, p. 49-61 13 p.

Research output: Contribution to journalReview article

The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin

Rognoni, E. & Walko, G., 3 May 2019, In : Stem Cells. 8, 5, 411.

Research output: Contribution to journalReview article

Open Access

Updates on the CDK4/6 Inhibitory Strategy and Combinations in Breast Cancer

Sobhani, N., D'Angelo, A., Pittacolo, M., Roviello, G., Miccoli, A., Corona, S. P., Bernocchi, O., Generali, D. & Otto, T., 6 Apr 2019, In : Stem Cells. 8, 4, 321.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Why study plovers? The significance of non-model organisms in avian ecology, behaviour and evolution

Székely, T., 1 Jul 2019, In : Journal of Ornithology. 160, 3, p. 923-933 11 p.

Research output: Contribution to journalReview article

Open Access
2018
6 Citations (Scopus)

Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies

Ermert, D. & Laabei, M., 1 Dec 2018, In : Journal of Innate Immunity. 11, 1, p. 3-12 10 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Chemical biology probes of mammalian GLUT structure and function

Holman, G. D., 20 Nov 2018, In : The Biochemical journal. 475, 22, p. 3511-3534 24 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
3 Downloads (Pure)

Current status of androgen receptor-splice variant 7 inhibitor niclosamide in castrate-resistant prostate-cancer

Sobhani, N., Generali, D., D'Angelo, A., Aieta, M. & Roviello, G., 31 Dec 2018, In : Investigational New Drugs. 36, 6, p. 1133-1137 5 p.

Research output: Contribution to journalReview article

Open Access
File

Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer

Sobhani, N., Ianza, A., D'Angelo, A., Roviello, G., Giudici, F., Bortul, M., Zanconati, F., Bottin, C. & Generali, D., 15 Jul 2018, In : Stem Cells. 7, 7, 76.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)
92 Downloads (Pure)

Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

Brown, N., Schrevens, S., van Dijck, P. & Goldman, G., 1 Apr 2018, In : Nature Microbiology. 3, p. 402–414 13 p.

Research output: Contribution to journalReview article

Open Access
File
Fungal Proteins
G-Protein-Coupled Receptors
GTP-Binding Proteins
Virulence
Fungi

How a DNA mimic catches and cleaves NF-kB

Acharya, K-R. & Cozier, G., 28 Sep 2018, In : Journal of Biological Chemistry. 293, 39, p. 15330-15331 2 p.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Metabolic gene clusters in eukaryotes

Nützmann, H. W., Scazzocchio, C. & Osbourn, A., 23 Nov 2018, In : Annual Review of Genetics. 52, p. 159-183 25 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Multifaceted impacts of bacteriophages in the plant microbiome

Koskella, B. & Taylor, T. B., 25 Aug 2018, In : Annual Review of Phytopathology. 56, p. 361-380 20 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)
8 Downloads (Pure)

Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring

Hussain, S., 1 Apr 2018, In : Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.

Research output: Contribution to journalReview article

Open Access
File
RNA Sequence Analysis
Transcriptome
RNA
DNA
Chemical analysis
11 Citations (Scopus)

Population genomics of bacterial host adaptation

Sheppard, S. K., Guttman, D. S. & Fitzgerald, J. R., 4 Jul 2018, In : Nature Reviews Genetics. 19, p. 549-565 17 p.

Research output: Contribution to journalReview article

Metagenomics
Bacteria
Food Supply
Livestock
Technology
11 Citations (Scopus)

RNAi as an emerging approach to control Fusarium head blight disease and mycotoxin contamination in cereals

Machado, A. K., Brown, N. A., Urban, M., Kanyuka, K. & Hammond-Kosack, K. E., 1 Apr 2018, In : Pest Management Science. 74, 4, p. 790-799 10 p.

Research output: Contribution to journalReview article

Open Access
Fusarium head blight
gene silencing
RNA interference
mycotoxins
Fusarium graminearum
2 Citations (Scopus)

Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.

Davies, J. R., Liu, S. M. & Acharya, K-R., 20 Oct 2018, In : Toxins . 10, 10, p. 1-18 18 p., 421.

Research output: Contribution to journalReview article

Open Access
2017
20 Citations (Scopus)

Alternative splicing and the evolution of phenotypic novelty

Bush, S. J., Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 5 Feb 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1713, 20150474.

Research output: Contribution to journalReview article

alternative splicing
Alternative Splicing
gene
Genes
Gene Duplication
8 Citations (Scopus)

Bacterial toxins: Offensive, defensive, or something else altogether?

Rudkin, J. K., McLoughlin, R. M., Preston, A. & Massey, R. C., 21 Sep 2017, In : PLoS Pathogens. 13, 9, e1006452.

Research output: Contribution to journalReview article

Open Access
Bacterial Toxins
Bacterial Physiological Phenomena
Aptitude
Life Style
Bacteria
12 Citations (Scopus)

Ca2+-permeable AMPA receptor: A new perspective on amyloid-beta mediated pathophysiology of Alzheimer's disease

Whitehead, G., Regan, P., Whitcomb, D. J. & Cho, K., 1 Jan 2017, In : Neuropharmacology. 112, Pt A, p. 221-227 7 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Dosage-sensitive genes in evolution and disease

Rice, A. M. & McLysaght, A., 1 Sep 2017, In : BMC Biology. 15, 1, p. 1-10 10 p., 78.

Research output: Contribution to journalReview article

Open Access
20 Citations (Scopus)

Estimating adult sex ratios in nature

Ancona, S., Dénes, F. V., Krüger, O., Székely, T. & Beissinger, S. R., 19 Sep 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1729, 20160313.

Research output: Contribution to journalReview article

Sex Ratio
sex ratio
Animals
Sex Characteristics
gender differences
6 Citations (Scopus)

Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Agwa, A. J., Henriques, S. T. & Schroeder, C. I., Dec 2017, In : Neuropharmacology. 127, p. 32-45 14 p.

Research output: Contribution to journalReview article

40 Citations (Scopus)

Non-Cholera Vibrios: The Microbial Barometer of Climate Change

Baker-Austin, C., Trinanes, J., Gonzalez-Escalona, N. & Martinez-Urtaza, J., 1 Jan 2017, In : Trends in Microbiology. 25, 1, p. 76-84 9 p.

Research output: Contribution to journalReview article

Vibrio
Climate Change
Vibrio vulnificus
Vibrio parahaemolyticus
Bacteria
16 Citations (Scopus)

Physiological and Pathophysiological Implications of Synaptic Tau

Regan, P., Whitcomb, D. J. & Cho, K., 1 Apr 2017, In : The Neuroscientist. 23, 2, p. 137-151 15 p.

Research output: Contribution to journalReview article

21 Citations (Scopus)

Sonic hedgehog signaling in limb development

Tickle, C. & Towers, M., 28 Feb 2017, In : Frontiers in Cell and Developmental Biology. 5, FEB, 14.

Research output: Contribution to journalReview article

Open Access
Hedgehogs
Limb Buds
Extremities
Mesoderm
Vertebrates
7 Citations (Scopus)

The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism

Hunt, V. L., Tsai, I. J., Selkirk, M. E. & Viney, M., 1 Mar 2017, In : Parasitology. 144, 3, p. 343-358 16 p.

Research output: Contribution to journalReview article

Open Access

The human gut virome: form and function

Ogilvie, L. A. & Jones, B., 30 Nov 2017, In : Emerging Topics in Life Sciences. 1, 4, p. 351-362 12 p.

Research output: Contribution to journalReview article

Bacteriophages
Microbiota
Ecosystem
Dysbiosis
Viruses
12 Citations (Scopus)

The promise of whole genome pathogen sequencing for the molecular epidemiology of emerging aquaculture pathogens

Bayliss, S. C., Verner-Jeffries, D. W., Bartie, K. L., Aanensen, D. M., Sheppard, S. K., Adams, A. & Feil, E. J., 3 Feb 2017, In : Frontiers in Microbiology. 8, 237708 .

Research output: Contribution to journalReview article

Open Access
Aquaculture
Molecular Epidemiology
Genome
Fast Foods
Bacterial Genomes
2 Citations (Scopus)

The structure of the S-layer of Clostridium difficile

Bradshaw, W. J., Roberts, A. K., Shone, C. C. & Acharya, K. R., 23 Nov 2017, In : Journal of Cell Communication and Signaling. p. 319-331 13 p.

Research output: Contribution to journalReview article

Open Access
Clostridium
Clostridium difficile
Protein Precursors
Pathogens
Bacteria
2016
236 Citations (Scopus)

Alternatives to antibiotics - a pipeline portfolio review

Czaplewski, L., Bax, R., Clokie, M., Dawson, M., Fairhead, H., Fischetti, V. A., Foster, S., Gilmore, B. F., Hancock, R. E. W., Harper, D., Henderson, I. R., Hilpert, K., Jones, B. V., Kadioglu, A., Knowles, D., Ólafsdóttir, S., Payne, D., Projan, S., Shaunak, S., Silverman, J. & 4 others, Thomas, C. M., Trust, T. J., Warn, P. & Rex, J. H., 13 Jan 2016, In : The Lancet Infectious Diseases. 16, 2, p. 239-51 13 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Bacteria
Modern 1601-history
Probiotics
Drug Industry
41 Citations (Scopus)

A molecular palaeobiological exploration of arthropod terrestrialization

Lozano-Fernandez, J., Carton, R., Tanner, A. R., Puttick, M. N., Blaxter, M., Vinther, J., Olesen, J., Giribet, G., Edgecombe, G. D. & Pisani, D., 19 Jul 2016, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 371, 1699, 20150133.

Research output: Contribution to journalReview article

Open Access
Arthropods
Biodiversity
Arachnida
arthropod
Myriapoda
6 Citations (Scopus)

Association between heavy precipitation events and waterborne outbreaks in four Nordic countries, 1992-2012

Herrador, B. G., De Blasio, B. F., Carlander, A., Ethelberg, S., Hygen, H. O., Kuusi, M., Lund, V., Löfdahl, M., MacDonald, E., Martinez-Urtaza, J., Nichols, G., Schönning, C., Sudre, B., Trönnberg, L., Vold, L., Semenza, J. C. & Nygård, K., 1 Dec 2016, In : Journal of Water and Health. 14, 6, p. 1019-1027 9 p.

Research output: Contribution to journalReview article

Scandinavian and Nordic Countries
Disease Outbreaks
rainfall
homeowner
logistics
66 Citations (Scopus)

Plant metabolic clusters - from genetics to genomics

Nuetzmann, H-W., Huang, A. & Osbourn, A., 11 Jul 2016, In : New Phytologist. 211, 3, p. 771-89 19 p.

Research output: Contribution to journalReview article

Genomics
Biological Products
genomics
Plant Genome
Multigene Family
8 Citations (Scopus)

Regulatory RNAs in Bacillus subtilis: a Gram-Positive Perspective on Bacterial RNA-Mediated Regulation of Gene Expression

Mars, R. A. T., Nicolas, P., Denham, E. L. & van Dijl, J. M., 26 Oct 2016, In : Microbiology and molecular biology reviews : MMBR. 80, 4, p. 1029-1057 29 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

Brown, N. A. & Goldman, G. H., 1 Mar 2016, In : Journal of Microbiology. 54, 3, p. 243-253 11 p.

Research output: Contribution to journalReview article

Aspergillus fumigatus
Mycoses
Virulence
Aspergillosis
Survival
21 Citations (Scopus)
1 Downloads (Pure)

The influence of historical climate changes on Southern Ocean marine predator populations: A comparative analysis

Younger, J. L., Emmerson, L. M. & Miller, K. J., 1 Feb 2016, In : Global Change Biology. 22, 2, p. 474-493 20 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)

The trans-kingdom identification of negative regulators of pathogen hypervirulence

Brown, N. A., Urban, M. & Hammond-Kosack, K. E., 1 Jan 2016, In : FEMS Microbiology Reviews. 40, 1, p. 19-40 22 p.

Research output: Contribution to journalReview article

Open Access
Virulence
Emerging Communicable Diseases
Plant Diseases
Host-Pathogen Interactions
Animal Diseases
9 Citations (Scopus)

Using functional genomics to decipher the complexity of microbial pathogenicity

Laabei, M. & Massey, R., 1 Aug 2016, In : Current Genetics. 62, 3, p. 523-525 3 p.

Research output: Contribution to journalReview article

Open Access
Genomics
Virulence
Bacteria
Infection
Staphylococcus aureus
2015
82 Citations (Scopus)

The human gut virome: a multifaceted majority

Ogilvie, L. A. & Jones, B. V., 11 Sep 2015, In : Frontiers in Microbiology. 6, 918.

Research output: Contribution to journalReview article

Open Access
Microbiota
Bacteriophages
Ecosystem
Technology
Virulence
2014
28 Citations (Scopus)

Engineered botulinum neurotoxins as new therapeutics

Masuyer, G., Chaddock, J. A., Foster, K. A. & Ravi Acharya, K., Jan 2014, In : Annual Review of Pharmacology and Toxicology. 54, p. 27-51 25 p.

Research output: Contribution to journalReview article

Neurotoxins
Therapeutics
Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
Proteolysis
SNARE Proteins
93 Citations (Scopus)

Gene clustering in plant specialized metabolism

Nuetzmann, H-W. & Osbourn, A., Apr 2014, In : Current Opinion in Biotechnology. 26, p. 91-9 9 p.

Research output: Contribution to journalReview article

Open Access
Multigene Family
Metabolism
Cluster Analysis
Genes
Metabolites
2013
55 Citations (Scopus)

Plectin-intermediate filament partnership in skin, skeletal muscle, and peripheral nerve

Castañón, M. J., Walko, G., Winter, L. & Wiche, G., Jul 2013, In : Histochemistry and Cell Biology. 140, 1, p. 33-53 21 p.

Research output: Contribution to journalReview article