Department of Biology & Biochemistry

Research Output 1970 2019

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Review article
2019

Being in a loop: how long non-coding RNAs organise genome architecture

Pisignano, G., Pavlaki, I. & Murrell, A., 9 Apr 2019, In : Essays in Biochemistry. 63, 1, p. 177-186 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Medium Chain Carboxylic Acids from Complex Organic Feedstocks by Mixed Culture Fermentation

De Groof, V., Coma, M., Arnot, T., Leak, D. J. & Lanham, A. B., 22 Jan 2019, In : Molecules. 24, 3, 398.

Research output: Contribution to journalReview article

Open Access

Sex ratios and bimaturism differ between temperature-dependent and genetic sex-determination systems in reptiles

Bókony, V., Milne, G., Pipoly, I., Székely, T. & Liker, A., 18 Feb 2019, In : BMC Evolutionary Biology. 19, 1, p. 57 57.

Research output: Contribution to journalReview article

Open Access

Updates on the CDK4/6 Inhibitory Strategy and Combinations in Breast Cancer

Sobhani, N., D'Angelo, A., Pittacolo, M., Roviello, G., Miccoli, A., Corona, S. P., Bernocchi, O., Generali, D. & Otto, T., 6 Apr 2019, In : Stem Cells. 8, 4, 321.

Research output: Contribution to journalReview article

Open Access
2018
2 Citations (Scopus)

Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies

Ermert, D. & Laabei, M., 28 Sep 2018, In : Journal of Innate Immunity. p. 1-10 10 p.

Research output: Contribution to journalReview article

Open Access

Chemical biology probes of mammalian GLUT structure and function

Holman, G. D., 20 Nov 2018, In : The Biochemical journal. 475, 22, p. 3511-3534 24 p.

Research output: Contribution to journalReview article

Open Access

Current status of androgen receptor-splice variant 7 inhibitor niclosamide in castrate-resistant prostate-cancer

Sobhani, N., Generali, D., D'Angelo, A., Aieta, M. & Roviello, G., 31 Dec 2018, In : Investigational New Drugs. 36, 6, p. 1133-1137 5 p.

Research output: Contribution to journalReview article

Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer

Sobhani, N., Ianza, A., D'Angelo, A., Roviello, G., Giudici, F., Bortul, M., Zanconati, F., Bottin, C. & Generali, D., 15 Jul 2018, In : Stem Cells. 7, 7, 76.

Research output: Contribution to journalReview article

Open Access

How a DNA mimic catches and cleaves NF-kB

Acharya, K-R. & Cozier, G., 28 Sep 2018, In : Journal of Biological Chemistry. 293, 39, p. 15330-15331 2 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Metabolic gene clusters in eukaryotes

Nützmann, H. W., Scazzocchio, C. & Osbourn, A., 23 Nov 2018, In : Annual Review of Genetics. 52, p. 159-183 25 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Multifaceted impacts of bacteriophages in the plant microbiome

Koskella, B. & Taylor, T. B., 25 Aug 2018, In : Annual Review of Phytopathology. 56, p. 361-380 20 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring

Hussain, S., 1 Apr 2018, In : Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.

Research output: Contribution to journalReview article

Open Access
File
RNA Sequence Analysis
Transcriptome
RNA
DNA
Chemical analysis
4 Citations (Scopus)

Population genomics of bacterial host adaptation

Sheppard, S. K., Guttman, D. S. & Fitzgerald, J. R., 4 Jul 2018, In : Nature Reviews Genetics. 19, p. 549-565 17 p.

Research output: Contribution to journalReview article

Metagenomics
Bacteria
Food Supply
Livestock
Technology
9 Citations (Scopus)

RNAi as an emerging approach to control Fusarium head blight disease and mycotoxin contamination in cereals

Machado, A. K., Brown, N. A., Urban, M., Kanyuka, K. & Hammond-Kosack, K. E., 1 Apr 2018, In : Pest Management Science. 74, 4, p. 790-799 10 p.

Research output: Contribution to journalReview article

Open Access
Fusarium head blight
gene silencing
RNA interference
mycotoxins
Fusarium graminearum
1 Citation (Scopus)

Ruminant and chicken: Important sources of campylobacteriosis in France despite a variation of source attribution in 2009 and 2015

Thépault, A., Rose, V., Quesne, S., Poezevara, T., Béven, V., Hirchaud, E., Touzain, F., Lucas, P., Méric, G., Mageiros, L., Sheppard, S. K., Chemaly, M. & Rivoal, K., 18 Jun 2018, In : Scientific Reports. 8, 1, 9305.

Research output: Contribution to journalReview article

Open Access
Multilocus Sequence Typing
Ruminants
France
Chickens
Genome

Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.

Davies, J. R., Liu, S. M. & Acharya, K-R., 20 Oct 2018, In : Toxins . 10, 10, 421.

Research output: Contribution to journalReview article

Open Access
2017
16 Citations (Scopus)

Alternative splicing and the evolution of phenotypic novelty

Bush, S. J., Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 5 Feb 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1713, 20150474.

Research output: Contribution to journalReview article

alternative splicing
Alternative Splicing
gene
Genes
Gene Duplication
6 Citations (Scopus)

Bacterial toxins: Offensive, defensive, or something else altogether?

Rudkin, J. K., McLoughlin, R. M., Preston, A. & Massey, R. C., 21 Sep 2017, In : PLoS Pathogens. 13, 9, e1006452.

Research output: Contribution to journalReview article

Open Access
Bacterial Toxins
Bacterial Physiological Phenomena
Aptitude
Life Style
Bacteria
18 Citations (Scopus)

Estimating adult sex ratios in nature

Ancona, S., Dénes, F. V., Krüger, O., Székely, T. & Beissinger, S. R., 19 Sep 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1729, 20160313.

Research output: Contribution to journalReview article

Sex Ratio
sex ratio
Animals
Sex Characteristics
gender differences
6 Citations (Scopus)

Gating modifier toxin interactions with ion channels and lipid bilayers: Is the trimolecular complex real?

Agwa, A. J., Henriques, S. T. & Schroeder, C. I., Dec 2017, In : Neuropharmacology. 127, p. 32-45 14 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Non-Cholera Vibrios: The Microbial Barometer of Climate Change

Baker-Austin, C., Trinanes, J., Gonzalez-Escalona, N. & Martinez-Urtaza, J., 1 Jan 2017, In : Trends in Microbiology. 25, 1, p. 76-84 9 p.

Research output: Contribution to journalReview article

Vibrio
Climate Change
Vibrio vulnificus
Vibrio parahaemolyticus
Bacteria
16 Citations (Scopus)

Sonic hedgehog signaling in limb development

Tickle, C. & Towers, M., 28 Feb 2017, In : Frontiers in Cell and Developmental Biology. 5, FEB, 14.

Research output: Contribution to journalReview article

Open Access
Hedgehogs
Limb Buds
Extremities
Mesoderm
Vertebrates
7 Citations (Scopus)

The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism

Hunt, V. L., Tsai, I. J., Selkirk, M. E. & Viney, M., 1 Mar 2017, In : Parasitology. 144, 3, p. 343-358 16 p.

Research output: Contribution to journalReview article

Open Access

The human gut virome: form and function

Ogilvie, L. A. & Jones, B., 30 Nov 2017, In : Emerging Topics in Life Sciences. 1, 4, p. 351-362 12 p.

Research output: Contribution to journalReview article

Bacteriophages
Microbiota
Ecosystem
Dysbiosis
Viruses
10 Citations (Scopus)

The promise of whole genome pathogen sequencing for the molecular epidemiology of emerging aquaculture pathogens

Bayliss, S. C., Verner-Jeffries, D. W., Bartie, K. L., Aanensen, D. M., Sheppard, S. K., Adams, A. & Feil, E. J., 3 Feb 2017, In : Frontiers in Microbiology. 8, 237708 .

Research output: Contribution to journalReview article

Open Access
Aquaculture
Molecular Epidemiology
Genome
Fast Foods
Bacterial Genomes

The structure of the S-layer of Clostridium difficile

Bradshaw, W. J., Roberts, A. K., Shone, C. C. & Acharya, K. R., 23 Nov 2017, In : Journal of Cell Communication and Signaling. p. 319-331 13 p.

Research output: Contribution to journalReview article

Open Access
Clostridium
Clostridium difficile
Protein Precursors
Pathogens
Bacteria
2016
197 Citations (Scopus)

Alternatives to antibiotics - a pipeline portfolio review

Czaplewski, L., Bax, R., Clokie, M., Dawson, M., Fairhead, H., Fischetti, V. A., Foster, S., Gilmore, B. F., Hancock, R. E. W., Harper, D., Henderson, I. R., Hilpert, K., Jones, B. V., Kadioglu, A., Knowles, D., Ólafsdóttir, S., Payne, D., Projan, S., Shaunak, S., Silverman, J. & 4 othersThomas, C. M., Trust, T. J., Warn, P. & Rex, J. H., 13 Jan 2016, In : The Lancet Infectious Diseases. 16, 2, p. 239-51 13 p.

Research output: Contribution to journalReview article

Anti-Bacterial Agents
Bacteria
Modern 1601-history
Probiotics
Drug Industry
34 Citations (Scopus)

A molecular palaeobiological exploration of arthropod terrestrialization

Lozano-Fernandez, J., Carton, R., Tanner, A. R., Puttick, M. N., Blaxter, M., Vinther, J., Olesen, J., Giribet, G., Edgecombe, G. D. & Pisani, D., 19 Jul 2016, In : Philosophical Transactions of the Royal Society B: Biological Sciences. 371, 1699, 20150133.

Research output: Contribution to journalReview article

Open Access
Arthropods
Biodiversity
Arachnida
arthropod
Myriapoda
6 Citations (Scopus)

Association between heavy precipitation events and waterborne outbreaks in four Nordic countries, 1992-2012

Herrador, B. G., De Blasio, B. F., Carlander, A., Ethelberg, S., Hygen, H. O., Kuusi, M., Lund, V., Löfdahl, M., MacDonald, E., Martinez-Urtaza, J., Nichols, G., Schönning, C., Sudre, B., Trönnberg, L., Vold, L., Semenza, J. C. & Nygård, K., 1 Dec 2016, In : Journal of Water and Health. 14, 6, p. 1019-1027 9 p.

Research output: Contribution to journalReview article

Scandinavian and Nordic Countries
Disease Outbreaks
rainfall
homeowner
logistics
59 Citations (Scopus)

Plant metabolic clusters - from genetics to genomics

Nuetzmann, H-W., Huang, A. & Osbourn, A., 11 Jul 2016, In : New Phytologist. 211, 3, p. 771-89 19 p.

Research output: Contribution to journalReview article

Genomics
Biological Products
genomics
Plant Genome
Multigene Family
7 Citations (Scopus)

Regulatory RNAs in Bacillus subtilis: a Gram-Positive Perspective on Bacterial RNA-Mediated Regulation of Gene Expression

Mars, R. A. T., Nicolas, P., Denham, E. L. & van Dijl, J. M., 26 Oct 2016, In : Microbiology and molecular biology reviews : MMBR. 80, 4, p. 1029-1057 29 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

Brown, N. A. & Goldman, G. H., 1 Mar 2016, In : Journal of Microbiology. 54, 3, p. 243-253 11 p.

Research output: Contribution to journalReview article

Aspergillus fumigatus
Mycoses
Virulence
Aspergillosis
Survival
17 Citations (Scopus)

The influence of historical climate changes on Southern Ocean marine predator populations: A comparative analysis

Younger, J. L., Emmerson, L. M. & Miller, K. J., 1 Feb 2016, In : Global Change Biology. 22, 2, p. 474-493 20 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

The trans-kingdom identification of negative regulators of pathogen hypervirulence

Brown, N. A., Urban, M. & Hammond-Kosack, K. E., 1 Jan 2016, In : FEMS Microbiology Reviews. 40, 1, p. 19-40 22 p.

Research output: Contribution to journalReview article

Open Access
Virulence
Emerging Communicable Diseases
Plant Diseases
Host-Pathogen Interactions
Animal Diseases
8 Citations (Scopus)

Using functional genomics to decipher the complexity of microbial pathogenicity

Laabei, M. & Massey, R., 1 Aug 2016, In : Current Genetics. 62, 3, p. 523-525 3 p.

Research output: Contribution to journalReview article

Open Access
Genomics
Virulence
Bacteria
Infection
Staphylococcus aureus
2015
73 Citations (Scopus)

The human gut virome: a multifaceted majority

Ogilvie, L. A. & Jones, B. V., 11 Sep 2015, In : Frontiers in Microbiology. 6, 918.

Research output: Contribution to journalReview article

Open Access
Microbiota
Bacteriophages
Ecosystem
Technology
Virulence
2014
28 Citations (Scopus)

Engineered botulinum neurotoxins as new therapeutics

Masuyer, G., Chaddock, J. A., Foster, K. A. & Ravi Acharya, K., Jan 2014, In : Annual Review of Pharmacology and Toxicology. 54, p. 27-51 25 p.

Research output: Contribution to journalReview article

Neurotoxins
Therapeutics
Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins
Proteolysis
SNARE Proteins
90 Citations (Scopus)

Gene clustering in plant specialized metabolism

Nuetzmann, H-W. & Osbourn, A., Apr 2014, In : Current Opinion in Biotechnology. 26, p. 91-9 9 p.

Research output: Contribution to journalReview article

Open Access
Multigene Family
Metabolism
Cluster Analysis
Genes
Metabolites
2013
46 Citations (Scopus)

Plectin-intermediate filament partnership in skin, skeletal muscle, and peripheral nerve

Castañón, M. J., Walko, G., Winter, L. & Wiche, G., Jul 2013, In : Histochemistry and Cell Biology. 140, 1, p. 33-53 21 p.

Research output: Contribution to journalReview article

2012

A new role for Grb10 signaling in the pancreas

Ward, A., Dec 2012, In : Diabetes. 61, 12, p. 3066-3067 2 p.

Research output: Contribution to journalReview article

Open Access
File
8 Citations (Scopus)

Evolutionary, ecological and biotechnological perspectives on plasmids resident in the human gut mobile metagenome

Ogilvie, L. A., Firouzmand, S. & Jones, B. V., 1 Jan 2012, In : Bioengineered Bugs. 3, 1, p. 13-31 19 p.

Research output: Contribution to journalReview article

Open Access
Metagenome
Interspersed Repetitive Sequences
Plasmids
Gene Pool
Genes
38 Citations (Scopus)

From genotype to phenotype: can systems biology be used to predict Staphylococcus aureus virulence?

Priest, N. K., Rudkin, J. K., Feil, E. J., Van Den Elsen, J. M. H., Cheung, A., Peacock, S. J., Laabei, M., Lucks, D. A., Recker, M. & Massey, R. C., Nov 2012, In : Nature Reviews Microbiology. 10, 11, p. 791-797 7 p.

Research output: Contribution to journalReview article

Systems Biology
Virulence
Staphylococcus aureus
Genotype
Phenotype
2011

Bacterial bile acid modification and potential pharmaceutical applications

Jones, B. V., 20 Oct 2011, In : Journal of Applied Therapeutic Research. 8, 3, p. 94-100 7 p.

Research output: Contribution to journalReview article

Bile Acids and Salts
choloylglycine hydrolase
Pharmaceutical Preparations
Microbiota
Metabolic Diseases
26 Citations (Scopus)

The human gut mobile metagenome: a metazoan perspective

Jones, B. V., 7 Apr 2011, In : Gut Microbes. 1, 6, p. 415-31 17 p.

Research output: Contribution to journalReview article

Open Access
Metagenome
Antitoxins
Microbiota
Plasmids
Metagenomics
2010
35 Citations (Scopus)

Plectin gene defects lead to various forms of epidermolysis bullosa simplex

Rezniczek, G. A., Walko, G. & Wiche, G., Jan 2010, In : Dermatologic Clinics. 28, 1, p. 33-41 9 p.

Research output: Contribution to journalReview article

59 Citations (Scopus)

The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation

Sherwood, V., Recino, A., Jeffries, A., Ward, A. & Chalmers, A. D., 2010, In : Biochemical Journal. 425, 2, p. 303-311 9 p.

Research output: Contribution to journalReview article

File
Association reactions
Neoplasms
Proteins
Tumors
Protein Domains
34 Citations (Scopus)

The role of scaffold proteins in JNK signalling

Engstrom, W., Ward, A. & Moorwood, K., Feb 2010, In : Cell Proliferation. 43, 1, p. 56-66 11 p.

Research output: Contribution to journalReview article

MAP Kinase Signaling System
Cell Cycle
Proteins
2007
18 Citations (Scopus)

Accessing the mobile metagenome of the human gut microbiota

Jones, B. V. & Marchesi, J. R., Nov 2007, In : Molecular Biosystems. 3, 11, p. 749-758 10 p.

Research output: Contribution to journalReview article

Metagenome
Ecosystem
Maintenance
Gastrointestinal Microbiome
2006
120 Citations (Scopus)

Regulation of growth and metabolism by imprinted genes

Smith, F. M., Garfield, A. S. & Ward, A., 2006, In : Cytogenetic and Genome Research. 113, 1-4, p. 279-291 13 p.

Research output: Contribution to journalReview article

Growth
Genes
Fetal Development
Genomic Imprinting
Alleles
2005
222 Citations (Scopus)

Advances in molecular ecology: Tracking trophic links through predator-prey food-webs

Sheppard, S. K. & Harwood, J. D., 10 Oct 2005, In : Functional Ecology. 19, 5, p. 751-762 12 p.

Research output: Contribution to journalReview article