Department of Biology & Biochemistry

Research Output

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Review article
2020

An overview of the clinical use of cabozantinib in the treatment of advanced non-clear-cell renal cell carcinoma (NCCRCC)

D'Angelo, A., Bagby, S., Di Pierro, G., Chirra, M., Nobili, S., Mini, E., Villari, D. & Roviello, G., May 2020, In : Critical Reviews in Oncology/Hematology. 149, 102921.

Research output: Contribution to journalReview article

File

A systematic review of intervention studies demonstrates the need to develop a minimum set of indicators to report the presence of burn wound infection

Davies, A., Spickett-Jones, F., Jenkins, A. T. A. & Young, A. E., 24 Apr 2020, In : Burns.

Research output: Contribution to journalReview article

Cabozantinib as a second-line treatment option in hepatocellular carcinoma

D’Angelo, A., Sobhani, N., Bagby, S., Casadei-Gardini, A. & Roviello, G., 12 May 2020, In : Expert Review of Clinical Pharmacology.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer

Roviello, G., D'Angelo, A., Petrioli, R., Roviello, F., Cianchi, F., Nobili, S., Mini, E. & Lavacchi, D., 26 May 2020, In : Translational Oncology. 13, 9, 100795.

Research output: Contribution to journalReview article

Open Access

Enzyme evolution and the temperature dependence of enzyme catalysis

Arcus, V. L., van der Kamp, M. W., Pudney, C. R. & Mulholland, A. J., 11 Jul 2020, In : Current Opinion in Structural Biology. 65, p. 96-101 6 p.

Research output: Contribution to journalReview article

Evaluation of targetable biomarkers for chimeric antigen receptor T-cell (CAR-T) in the treatment of pancreatic cancer: a systematic review and meta-analysis of preclinical studies

Sahlolbei, M., Dehghani, M., Kheiri Yeghane Azar, B., Vafaei, S., Roviello, G., D'Angelo, A., Madjd, Z. & Kiani, J., 16 Jun 2020, In : Exercise Immunology Review. p. 1-10 10 p.

Research output: Contribution to journalReview article

High Aspect Ratio-Nanostructured Surfaces as Biological Metamaterials

Higgins, S., Becce, M., Belessiotis-Richards, A., Seong, H., Sero, J. & Stevens, M., 5 Mar 2020, In : Advanced Materials. 32, 9, 1903862.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Integrating transposable elements in the 3D genome

Bousios, A., Nützmann, H. W., Buck, D. & Michieletto, D., 4 Feb 2020, In : Mobile DNA. 11, 1, 8.

Research output: Contribution to journalReview article

Open Access
File
17 Downloads (Pure)

MSI and EBV Positive Gastric Cancer's Subgroups and Their Link With Novel Immunotherapy

Rodriquenz, M. G., Roviello, G., D'Angelo, A., Lavacchi, D., Roviello, F. & Polom, K., 11 May 2020, In : Journal of Clinical Medicine. 9, 5, 1427.

Research output: Contribution to journalReview article

Open Access
File

Mutant p53 as an Antigen in Cancer Immunotherapy

Sobhani, N., D'Angelo, A., Wang, X., Young, K. H., Generali, D. & Li, Y., 8 Jun 2020, In : International Journal of Molecular Sciences. 21, 11, p. 1-21 21 p., 4087.

Research output: Contribution to journalReview article

Open Access
File

On a new proposed mechanism of 5-fluorouracil-mediated cytotoxicity

Hussain, S., 1 May 2020, In : Trends in Cancer. 6, 5, p. 365-368 4 p.

Research output: Contribution to journalReview article

Role of novel hormonal therapies in the management of non-metastatic castration-resistant prostate cancer: a literature-based meta-analysis of randomized trials

Roviello, G., Gatta Michelet, M. R., D'Angelo, A., Nobili, S. & Mini, E., 31 Jul 2020, In : Clinical and Translational Oncology . 22, p. 1033-1039 7 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
24 Downloads (Pure)

Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery

Madden, S. K. & Itzhaki, L. S., 1 Jul 2020, In : Biochimica Et Biophysica Acta-Proteins and Proteomics. 1868, 7, 140405.

Research output: Contribution to journalReview article

The emperor penguin - Vulnerable to projected rates of warming and sea ice loss

Trathan, P. N., Wienecke, B., Barbraud, C., Jenouvrier, S., Kooyman, G., Le Bohec, C., Ainley, D. G., Ancel, A., Zitterbart, D. P., Chown, S. L., Larue, M., Cristofari, R., Younger, J., Clucas, G., Bost, C., Brown, J. A., Gillett, H. J. & Fretwell, P. T., 31 Jan 2020, In : Biological Conservation. 241, 108216.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

The role of stereochemistry of antibiotic agents in the development of antibiotic resistance in the environment

Elder, F. C. T., Feil, E. J., Snape, J. N., Gaze, W. H. & Kasprzyk-Hordern, B. A., 30 Jun 2020, In : Environment International. 139, 105681.

Research output: Contribution to journalReview article

Open Access

TRK fusion positive cancers: From first clinical data of a TRK inhibitor to future directions

Roviello, G., D'Angelo, A., Sciortino, M., Mini, E., Nobili, S., De Logu, F. & Massi, D., 31 May 2020, In : Critical Reviews in Oncology/Hematology. 152, 103011.

Research output: Contribution to journalReview article

Tumor-Agnostic Treatment for Cancer: When How is Better than Where

Lavacchi, D., Roviello, G. & D'Angelo, A., Jun 2020, In : Clinical Drug Investigation. 40, 6, p. 519-527

Research output: Contribution to journalReview article

Open Access
File
2 Citations (Scopus)
6 Downloads (Pure)
2019

A century of bias in genetics and evolution

Hurst, L., 12 Jun 2019, In : Heredity. 123, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

Open Access
File
72 Downloads (Pure)

Being in a loop: how long non-coding RNAs organise genome architecture

Pisignano, G., Pavlaki, I. & Murrell, A., 9 Apr 2019, In : Essays in Biochemistry. 63, 1, p. 177-186 10 p.

Research output: Contribution to journalReview article

Open Access
File
3 Citations (Scopus)
8 Downloads (Pure)

Borrelia bavariensis: Vector Switch, Niche Invasion, and Geographical Spread of a Tick-Borne Bacterial Parasite

Margos, G., Fingerle, V. & Reynolds, S., 23 Oct 2019, In : Frontiers in Ecology and Evolution. 7, p. 1-20 20 p., 401.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Cooking up the perfect insect: Aristotle's transformational idea about the complete metamorphosis of insects

Reynolds, S., 23 Aug 2019, In : Philosophical transactions B: Biological Sciences. 374, 1783, p. 1-16 16 p., 20190074.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
44 Downloads (Pure)

Corticosteroid switch after progression on abiraterone acetate plus prednisone

Roviello, G., Sobhani, N., Corona, S. P. & D'Angelo, A., 8 Nov 2019, In : International Journal of Clinical Oncology. 7 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Medium Chain Carboxylic Acids from Complex Organic Feedstocks by Mixed Culture Fermentation

De Groof, V., Coma, M., Arnot, T., Leak, D. J. & Lanham, A. B., 22 Jan 2019, In : Molecules. 24, 3, p. 1-32 32 p., 398.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)

Microbial fuel cells: An overview of current technology

Slate, A. J., Whitehead, K. A., Brownson, D. A. C. & Banks, C. E., 1 Mar 2019, In : Renewable and Sustainable Energy Reviews. 101, p. 60-81 22 p.

Research output: Contribution to journalReview article

81 Citations (Scopus)

Microglia and the aging brain: are senescent microglia the key to neurodegeneration?

Angelova, D. M. & Brown, D. R., 1 Dec 2019, In : Journal of Neurochemistry. 151, 6, p. 676-688 13 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Novel Agents in Heavily Pretreated Metastatic Gastric Cancer: More Shadows Than Lights

Roviello, G., D'Angelo, A., Roudi, R., Petrioli, R. & Mini, E., 4 Jul 2019, In : Journal of oncology. 2019, 9 p., 5692317.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)

Sex ratios and bimaturism differ between temperature-dependent and genetic sex-determination systems in reptiles

Bókony, V., Milne, G., Pipoly, I., Székely, T. & Liker, A., 18 Feb 2019, In : BMC Evolutionary Biology. 19, 1, p. 57 57.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

The hijackers guide to escaping complement: Lessons learned from pathogens

Ermert, D., Ram, S. & Laabei, M., 1 Oct 2019, In : Molecular Immunology. 114, p. 49-61 13 p.

Research output: Contribution to journalReview article

Open Access
File
6 Citations (Scopus)
2 Downloads (Pure)

The Roles of YAP/TAZ and the Hippo Pathway in Healthy and Diseased Skin

Rognoni, E. & Walko, G., 3 May 2019, In : Stem Cells. 8, 5, 411.

Research output: Contribution to journalReview article

Open Access

Updates on the CDK4/6 Inhibitory Strategy and Combinations in Breast Cancer

Sobhani, N., D'Angelo, A., Pittacolo, M., Roviello, G., Miccoli, A., Corona, S. P., Bernocchi, O., Generali, D. & Otto, T., 6 Apr 2019, In : Stem Cells. 8, 4, 321.

Research output: Contribution to journalReview article

Open Access

Why study plovers? The significance of non-model organisms in avian ecology, behaviour and evolution

Székely, T., 1 Jul 2019, In : Journal of Ornithology. 160, 3, p. 923-933 11 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2018

Catch Me if You Can: Streptococcus pyogenes Complement Evasion Strategies

Ermert, D. & Laabei, M., 1 Dec 2018, In : Journal of Innate Immunity. 11, 1, p. 3-12 10 p.

Research output: Contribution to journalReview article

Open Access
13 Citations (Scopus)

Chemical biology probes of mammalian GLUT structure and function

Holman, G. D., 20 Nov 2018, In : The Biochemical journal. 475, 22, p. 3511-3534 24 p.

Research output: Contribution to journalReview article

Open Access
12 Citations (Scopus)

Current status of androgen receptor-splice variant 7 inhibitor niclosamide in castrate-resistant prostate-cancer

Sobhani, N., Generali, D., D'Angelo, A., Aieta, M. & Roviello, G., 31 Dec 2018, In : Investigational New Drugs. 36, 6, p. 1133-1137 5 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
45 Downloads (Pure)

Current Status of Fibroblast Growth Factor Receptor-Targeted Therapies in Breast Cancer

Sobhani, N., Ianza, A., D'Angelo, A., Roviello, G., Giudici, F., Bortul, M., Zanconati, F., Bottin, C. & Generali, D., 15 Jul 2018, In : Stem Cells. 7, 7, 76.

Research output: Contribution to journalReview article

Open Access

Fungal G-protein-coupled receptors: mediators of pathogenesis and targets for disease control

Brown, N., Schrevens, S., van Dijck, P. & Goldman, G., 1 Apr 2018, In : Nature Microbiology. 3, p. 402–414 13 p.

Research output: Contribution to journalReview article

Open Access
File
15 Citations (Scopus)
163 Downloads (Pure)

How a DNA mimic catches and cleaves NF-kB

Acharya, K-R. & Cozier, G., 28 Sep 2018, In : Journal of Biological Chemistry. 293, 39, p. 15330-15331 2 p.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Metabolic gene clusters in eukaryotes

Nützmann, H. W., Scazzocchio, C. & Osbourn, A., 23 Nov 2018, In : Annual Review of Genetics. 52, p. 159-183 25 p.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Multifaceted impacts of bacteriophages in the plant microbiome

Koskella, B. & Taylor, T. B., 25 Aug 2018, In : Annual Review of Phytopathology. 56, p. 361-380 20 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Native RNA-Sequencing Throws its Hat into the Transcriptomics Ring

Hussain, S., 1 Apr 2018, In : Trends in Biochemical Sciences. 43, 4, p. 225-227 3 p.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
27 Downloads (Pure)

Population genomics of bacterial host adaptation

Sheppard, S. K., Guttman, D. S. & Fitzgerald, J. R., 4 Jul 2018, In : Nature Reviews Genetics. 19, p. 549-565 17 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

RNAi as an emerging approach to control Fusarium head blight disease and mycotoxin contamination in cereals

Machado, A. K., Brown, N. A., Urban, M., Kanyuka, K. & Hammond-Kosack, K. E., 1 Apr 2018, In : Pest Management Science. 74, 4, p. 790-799 10 p.

Research output: Contribution to journalReview article

Open Access
32 Citations (Scopus)

Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.

Davies, J. R., Liu, S. M. & Acharya, K-R., 20 Oct 2018, In : Toxins . 10, 10, p. 1-18 18 p., 421.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)
2017

Alternative splicing and the evolution of phenotypic novelty

Bush, S. J., Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 5 Feb 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1713, 20150474.

Research output: Contribution to journalReview article

30 Citations (Scopus)

Bacterial toxins: Offensive, defensive, or something else altogether?

Rudkin, J. K., McLoughlin, R. M., Preston, A. & Massey, R. C., 30 Sep 2017, In : PLoS Pathogens. 13, 9, e1006452.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)

Ca2+-permeable AMPA receptor: A new perspective on amyloid-beta mediated pathophysiology of Alzheimer's disease

Whitehead, G., Regan, P., Whitcomb, D. J. & Cho, K., 1 Jan 2017, In : Neuropharmacology. 112, Pt A, p. 221-227 7 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

Dosage-sensitive genes in evolution and disease

Rice, A. M. & McLysaght, A., 1 Sep 2017, In : BMC Biology. 15, 1, p. 1-10 10 p., 78.

Research output: Contribution to journalReview article

Open Access
16 Citations (Scopus)

Estimating adult sex ratios in nature

Ancona, S., Dénes, F. V., Krüger, O., Székely, T. & Beissinger, S. R., 19 Sep 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1729, 20160313.

Research output: Contribution to journalReview article

30 Citations (Scopus)