Department of Biology & Biochemistry

Research Output

2018

The effects of cannabidiol on impulsivity and memory during abstinence in cigarette dependent smokers

Hindocha, C., Freeman, T. P., Grabski, M., Crudgington, H., Davies, A. C., Stroud, J. B., Das, R. K., Lawn, W., Morgan, C. J. A. & Curran, H. V., 15 May 2018, In : Scientific Reports. 8, 1, p. 1-7 7 p., 7568.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

The importance of cross-disciplinary research to combat antimicrobial resistance: Introducing a new pop-up journal, X-AMR

Knight, G., Lambert, H., Feil, E., Holmes, M. & Lindsay, J., 1 Aug 2018, In : Microbiology (United Kingdom). 4, 7, p. 1-2 2 p., 000684.

Research output: Contribution to journalEditorial

Open Access

The Interrelationships of Land Plants and the Nature of the Ancestral Embryophyte

Puttick, M. N., Morris, J. L., Williams, T. A., Cox, C. J., Edwards, D., Kenrick, P., Pressel, S., Wellman, C. H., Schneider, H., Pisani, D. & Donoghue, P. C. J., 5 Mar 2018, In : Current Biology. 28, 5, p. 733-745.e2 13 p.

Research output: Contribution to journalArticle

Open Access
95 Citations (Scopus)

The long non-coding RNA Paupar promotes KAP1-dependent chromatin changes and regulates olfactory bulb neurogenesis

Pavlaki, I., Alammari, F., Sun, B., Clark, N., Sirey, T., Lee, S., Woodcock, D. J., Ponting, C. P., Szele, F. G. & Vance, K. W., 15 May 2018, In : The EMBO Journal. 37, 10, p. 1-16 16 p., e98219.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

The Potential of Isolation Source to Predict Colonization in Avian Hosts: A Case Study in Campylobacter jejuni Strains From Three Bird Species

Atterby, C., Mourkas, E., Méric, G., Pascoe, B., Wang, H., Waldenström, J., Sheppard, S. K., Olsen, B., Järhult, J. D. & Ellström, P., 29 Mar 2018, In : Frontiers in Microbiology. 9, p. 1-12 12 p., 591.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

The rational design of affinity attenuated OmCI for the purification of Complement C5

Macpherson, A., Liu, X., Dedi, N., Kennedy, J., Carrington, B., Durrant, O., Heywood, S., van den Elsen, J. & Lawson, A. D. G., 7 Sep 2018, In : The Journal of biological chemistry. 293, 36, p. 14112-14121 10 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
52 Downloads (Pure)

The synthesis and kinetic evaluation of aryl α-aminophosphonates as novel inhibitors of T. cruzi trans-sialidase

Chen, Z., Marce Villa, P., Resende, R., Alzari, P. M., Frasch, A. C., Van Den Elsen, J., Crennell, S. & Watts, A., 5 Oct 2018, In : European Journal of Medicinal Chemistry. 158, p. 25-33 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
22 Downloads (Pure)

The timescale of early land plant evolution

Morris, J. L., Puttick, M. N., Clark, J. W., Edwards, D., Kenrick, P., Pressel, S., Wellman, C. H., Yang, Z., Schneider, H. & Donoghue, P. C. J., 6 Mar 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 10, p. E2274-E2283 10 p.

Research output: Contribution to journalArticle

Open Access
136 Citations (Scopus)

Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

Gratte, F. D., Pasic, S., Olynyk, J. K., Yeoh, G. C. T., Tosh, D., Coombe, D. R. & Tirnitz-Parker, J. E. E., 12 Mar 2018, In : Scientific Reports. 8, 1, p. 1-13 13 p., 4385.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Transmembrane but not soluble helices fold inside the ribosome tunnel

Bañó-Polo, M., Baeza-Delgado, C., Tamborero, S., Hazel, A., Grau, B., Nilsson, I. M., Whitley, P., Gumbart, J. C., von Heijne, G. & Mingarro, I., 7 Dec 2018, In : Nature Communications. 9, 1, 5246.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Transposon Insertion Sequencing Elucidates Novel Gene Involvement in Susceptibility and Resistance to Phages T4 and T7 in Escherichia coli O157

Cowley, L., Low, A. S., Pickard, D., Boinett, C. J., Dallman, T. J., Day, M., Perry, N., Gally, D. L., Parkhill, J., Jenkins, C. & Cain, A. K., 24 Jul 2018, In : mBio. 9, 4, p. 1-15 15 p., e00705-18.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Trends in fluoroquinolone resistance in Campylobacter

Sproston, E. L., Wimalarathna, H. M. L. & Sheppard, S. K., 1 Aug 2018, In : Microbial Genomics. 4, 8, p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access
20 Citations (Scopus)

Uncovering the relationship between the change in heat capacity for enzyme catalysis and vibrational frequency through isotope effect studies

Jones, H. B. L., Crean, R. M., Matthews, C., Troya, A. B., Danson, M. J., Bull, S. D., Arcus, V. L., Van Der Kamp, M. W. & Pudney, C. R., 1 Jun 2018, In : ACS Catalysis. 8, 6, p. 5340-5349 10 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
51 Downloads (Pure)

Unlocking Nicotinic Selectivity via Direct C‒H Functionalization of (−)-Cytisine

Rego Campello, H., Del Villar, S. G., Honraedt, A., Minguez, T., Oliviera, A. S., Ranaghan, K. E., Shoemark, D., Bermudez, I., Gotti, C., Sessions, R., Mulholland, A., Wonnacott, S. & Gallagher, T., 12 Jul 2018, In : Chem. 4, 7, p. 1710-1725 16 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Using the Mus musculus hybrid zone to assess covariation and genetic architecture of limb bone lengths

Škrabar, N., Turner, L. M., Pallares, L. F., Harr, B. & Tautz, D., 1 Jul 2018, In : Molecular Ecology Resources. 18, 4, p. 908-921 14 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
28 Downloads (Pure)

Variations in the Botulinum Neurotoxin Binding Domain and the Potential for Novel Therapeutics.

Davies, J. R., Liu, S. M. & Acharya, K-R., 20 Oct 2018, In : Toxins . 10, 10, p. 1-18 18 p., 421.

Research output: Contribution to journalReview article

Open Access
4 Citations (Scopus)

Weak epistasis may drive adaptation in recombining bacteria

Arnold, B. J., Gutmann, M. U., Grad, Y. H., Sheppard, S. K., Corander, J., Lipsitch, M. & Hanage, W. P., 1 Mar 2018, In : Genetics. 208, 3, p. 1247-1260 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Well-annotated microRNAomes do not evidence pervasive miRNA loss

Tarver, J. E., Taylor, R. S., Puttick, M. N., Lloyd, G. T., Pett, W., Fromm, B., Schirrmeister, B. E., Pisani, D., Peterson, K. J. & Donoghue, P. C. J., 1 Jun 2018, In : Genome biology and evolution. 10, 6, p. 1457-1470 14 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

What is a stem cell?

Slack, J. M. W., 1 Sep 2018, In : Wiley Interdisciplinary Reviews: Developmental Biology. 7, 5, p. 1-15 15 p., e323.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
46 Downloads (Pure)

Whole genome sequencing and phylogenetic analysis of strains of the agent of Lyme disease Borrelia burgdorferi from Canadian emergence zones

Tyler, S., Tyson, S., Dibernardo, A., Drebot, M., Feil, E. J., Graham, M., Knox, N. C., Lindsay, L. R., Margos, G., Mechai, S., Van Domselaar, G., Thorpe, H. A. & Ogden, N. H., 12 Jul 2018, In : Scientific Reports. 8, 1, p. 1-12 12 p., 10552.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Within-host Mycobacterium tuberculosis diversity and its utility for inferences of transmission

Martin, M. A., Lee, R. S., Cowley, L., Gardy, J. L. & Hanage, W. P., Oct 2018, In : Microbial Genomics. 4, 10, p. 1-8 8 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

לעצטע מעשׂים־טובֿים פֿון אַ טאָמײטע

Translated title of the contribution: A Tomato's Last Good DeedsShapiro, M. (Translator) & Selikovitch, G., 21 Nov 2018, In : In geveb.

Research output: Contribution to journalArticle

משיח אין אַמעריקע

Translated title of the contribution: Messiah in America [excerpt]: Translation by Michael ShapiroShapiro, M. (Translator) & Nadir, M., 4 Jul 2018, In : In geveb.

Research output: Contribution to journalArticle

Open Access
2017

A cationic diode based on asymmetric nafion film deposits

He, D., Aaronson, B. D. B., Madrid, E., Fan, L., Doughty, J., Mathwig, K., Bond, A. M., Mckeown, N. B. & Marken, F., 29 Mar 2017, In : ACS Applied Materials and Interfaces. 9, 12, p. 11272-11278

Research output: Contribution to journalArticle

20 Citations (Scopus)

Accessory gene regulator (Agr) functionality in Staphylococcus aureus derived from lower respiratory tract infections

Gomes-Fernandes, M., Laabei, M., Pagan, N., Hidalgo, J., Molinos, S., Villar Hernandez, R., Domínguez-Villanueva, D., Jenkins, A. T. A., Lacoma, A. & Prat, C., 1 Apr 2017, In : PLoS ONE. 12, 4, e0175552.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

A comparative genomics study of Staphylococcus epidermidis from orthopedic device-related infections correlated with patient outcome

Post, V., Harris, L. G., Morgenstern, M., Mageiros, L., Hitchings, M. D., Méric, G., Pascoe, B., Sheppard, S. K., Richards, R. G. & Moriarty, T. F., 1 Oct 2017, In : Journal of Clinical Microbiology. 55, 10, p. 3089-3103 00881-17.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
113 Downloads (Pure)

A complete thermodynamic analysis of enzyme turnover links the free energy landscape to enzyme catalysis

Jones, H. B. L., Wells, S. A., Prentice, E. J., Kwok, A., Liang, L. L., Arcus, V. L. & Pudney, C. R., 1 Sep 2017, In : FEBS Journal. 284, 17, p. 2829-2842 14 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Activity-Based Probes for HECT E3 ubiquitin ligases

Byrne, R., Mund, T. & Licchesi, J., 18 Jul 2017, In : ChemBiochem. 18, 14, p. 1415–1427 13 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

A curated genome-scale metabolic model of Bordetella pertussis metabolism

Fyson, N., King, J., Belcher, T., Preston, A. & Colijn, C., 17 Jul 2017, In : Plos Computational Biology. 13, 7, e1005639.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
128 Downloads (Pure)
Open Access
3 Citations (Scopus)

Adult sex ratio and operational sex ratio exhibit different temporal dynamics in the wild

Carmona-Isunza, M. C., Ancona, S., Székely, T., Ramallo-González, A. P., Cruz-López, M., Serrano-Meneses, M. A. & Küpper, C., 1 Apr 2017, In : Behavioral Ecology. 28, 2, p. 523-532 10 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Adult sex ratios and reproductive strategies: A critical re-examination of sex differences in human and animal societies

Schacht, R., Kramer, K. L., Székely, T. & Kappeler, P. M., 19 Sep 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1729, 20160309.

Research output: Contribution to journalEditorial

10 Citations (Scopus)

Adult sex ratios and their implications for cooperative breeding in birds

Komdeur, J., Székely, T., Long, X. & Kingma, S. A., 19 Sep 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1729, 20160322.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A flexible e-learning resource promoting the critical reading of scientific papers for science undergraduates

Letchford, J., Corradi, H. & Day, T., Nov 2017, In : Biochemistry and Molecular Biology Education. 45, 6, p. 483–490 8 p.

Research output: Contribution to journalArticle

Open Access
File
59 Downloads (Pure)

A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells

Walko, G., Woodhouse, S., Pisco, A. O., Rognoni, E., Liakath-Ali, K., Lichtenberger, B. M., Mishra, A., Telerman, S. B., Viswanathan, P., Logtenberg, M., Renz, L. M., Donati, G., Quist, S. R. & Watt, F. M., 23 Mar 2017, In : Nature Communications. 8, p. 1-16 16 p., 14744.

Research output: Contribution to journalArticle

Open Access
31 Citations (Scopus)

Albugo-imposed changes to tryptophan-derived antimicrobial metabolite biosynthesis may contribute to suppression of non-host resistance to Phytophthora infestans in Arabidopsis thaliana

Prince, D. C., Rallapalli, G., Xu, D., Schoonbeek, H. J., Çevik, V., Asai, S., Kemen, E., Cruz-Mireles, N., Kemen, A., Belhaj, K., Schornack, S., Kamoun, S., Holub, E. B., Halkier, B. A. & Jones, J. D. G., 20 Mar 2017, In : BMC Biology. 15, 1, 20.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
Open Access
File
18 Citations (Scopus)
129 Downloads (Pure)

Alpha-synuclein ferrireductase activity is detectible in vivo, is altered in Parkinson's disease and increases the neurotoxicity of DOPAL

McDowall, J. S., Ntai, I., Honeychurch, K. C., Hart, J. P., Colin, P., Schneider, B. L. & Brown, D., 1 Dec 2017, In : Molecular and Cellular Neuroscience. 85, p. 1-11 11 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
125 Downloads (Pure)

Alternative splicing and the evolution of phenotypic novelty

Bush, S. J., Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 5 Feb 2017, In : Proceedings of the Royal Society B: Biological Sciences. 372, 1713, 20150474.

Research output: Contribution to journalReview article

25 Citations (Scopus)

A machine-compiled microbial supertree from figure-mining thousands of papers

Mounce, R., Murray-Rust, P. & Wills, M., 9 May 2017, In : Research Ideas and Outcomes. 3, e13589.

Research output: Contribution to journalArticle

File
139 Downloads (Pure)

A manifesto for reproducible science

Munafò, M. R., Nosek, B. A., Bishop, D. V. M., Button, K. S., Chambers, C. D., Percie Du Sert, N., Simonsohn, U., Wagenmakers, E., Ware, J. J. & Ioannidis, J. P. A., 10 Jan 2017, In : Nature Human Behaviour. 1, 1, p. 0021

Research output: Contribution to journalArticle

Open Access
644 Citations (Scopus)

A modular sensor platform based on a versatile supramolecular multi-enzyme complex directly attached to graphene

Alshammari, A., Posner, M., Upadhyay, A., Bashir, M., Marken, F., Bagby, S. & Ilie, A., 2017.

Research output: Contribution to conferencePoster

An abelisaurid from the latest Cretaceous (late Maastrichtian) of Morocco, North Africa

Longrich, N. R., Pereda-Suberbiola, X., Jalil, N. E., Khaldoune, F. & Jourani, E., 1 Aug 2017, In : Cretaceous Research. 76, p. 40-52 13 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Ancestral ecological reconstructions and evidence of canopy destruction reveal strong ecological selectivity among birds across the K-Pg mass extinction.

Field, D., Bercovici, A., Dunn, R., Fastovsky, D., Berv, J. S. & Gauthier, J., 2017.

Research output: Contribution to conferenceAbstract

Aneurysm Severity is Increased by Combined Mmp-7 Deletion and N-cadherin Mimetic (EC4-Fc) Over-Expression

Lyon, C. A., Williams, H., Bianco, R., Simmonds, S. J., Brown, B. A., Wadey, K. S., Smith, F. C. T., Johnson, J. L. & George, S. J., 11 Dec 2017, In : Scientific Reports. 7, 1, 17432.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

A new basal snake from the mid-Cretaceous of Morocco

Klein, C. G., Longrich, N. R., Ibrahim, N., Zouhri, S. & Martill, D. M., 1 Apr 2017, In : Cretaceous Research. 72, p. 134-141 8 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
157 Downloads (Pure)

An Extracellular Polysaccharide Locus Required for Transmission of Bordetella bronchiseptica

Dewan, K. K., Taylor-Mulneix, D. L., Hilburger, L. J., Rivera, I., Preston, A. & Harvill, E. T., 1 Oct 2017, In : Journal of Infectious Diseases. 216, 7, p. 899-906

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

An historical perspective on the pioneering experiments of John Saunders

Tickle, C., 15 Jun 2017, In : Developmental Biology.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Animal regeneration: Ancestral character or evolutionary novelty?

Slack, J. M. W., 1 Sep 2017, In : EMBO Reports. 18, 9, p. 1497-1508

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
35 Downloads (Pure)

An integrated biorefinery concept for conversion of sugar beet pulp into value-added chemicals and pharmaceutical intermediates

Cárdenas-Fernández, M., Bawn, M., Hamley-Bennett, C., Bharat, P. K. V., Subrizi, F., Suhaili, N., Ward, D. P., Bourdin, S., Dalby, P. A., Hailes, H. C., Hewitson, P., Ignatova, S., Kontoravdi, C., Leak, D. J., Shah, N., Sheppard, T. D., Ward, J. M. & Lye, G. J., 1 Sep 2017, In : Faraday Discussions. 202, p. 415-431

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)