Department of Biology & Biochemistry

Research Output

¿Qué ocurriría en la naturaleza si desaparecieran los insectos?

Reynolds, S., 24 Feb 2019, The Conversation.

Research output: Contribution to specialist publicationArticle

(-)Epicatechin stimulates ERK-dependent cyclic AMP response element activity and up-regulates GluR2 in cortical neurons

Schroeter, H., Bahia, P., Spencer, J. P. E., Sheppard, O., Rattray, M., Cadenas, E., Rice-Evans, C. & Williams, R. J., Jun 2007, In : Journal of Neurochemistry. 101, 6, p. 1596-1606 11 p.

Research output: Contribution to journalArticle

125 Citations (Scopus)

[3H]-methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors

Lind, R. J., Hardick, D. J., Blagbrough, I. S., Potter, B. V. L., Wolstenholme, A. J., Davies, A. R. L., Clough, M. S., Earley, F. G. P., Reynolds, S. E. & Wonnacott, S., 2001, In : Insect Biochemistry and Molecular Biology. 31, 6-7, p. 533-542

Research output: Contribution to journalArticle

22 Citations (Scopus)

[Book Review]: Evolutionary Computation: A Unified Approach

Wolf, J. B., 2007, In : The Quarterly Review of Biology. 82, 1, p. 46 1 p.

Research output: Contribution to journalArticle

10 GHz hybrid modelocking of monolithic InGaAs quantum dot lasers

Thompson, M. G., Marinelli, C., Tan, K. T., Williams, K. A., Penty, R. V., White, I. H., Kaiander, I. N., Sellin, R. L., Bimberg, D., Kang, D. J., Blamire, M. G., Visinka, F., Jochum, S. & Hansmann, S., 24 Jul 2003, In : Electronics Letters. 39, 15, p. 1121-1122 2 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

2-aminoethoxydiphenylborane is an acute inhibitor of directly photosensitive retinal ganglion cell activity in vitro and in vivo

Sekaran, S., Lall, G. S., Ralphs, K. L., Wolstenholme, A. J., Lucas, R. J., Foster, R. G. & Hankins, M. W., 2007, In : Journal of Neuroscience. 27, 15, p. 3981-3986 6 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)

2-Oxoacid dehydrogenase multienzyme complexes in the halophilic Archaea ? Gene sequences and protein structural predictions

Jolley, K. A., Maddocks, D. G., Gyles, S. L., Mullan, Z., Tang, S. L., Dyall-Smith, M. L., Hough, D. W. & Danson, M. J., 2000, In : Microbiology. 146, p. 1061-1069 9 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

3D expression patterns of cell cycle genes in the developing chick wing and comparison with expression patterns of genes implicated in digit specification

Welten, M., Pavlovska, G., Chen, Y., Teruoka, Y., Fisher, M., Bangs, F., Towers, M. & Tickle, C., May 2011, In : Developmental Dynamics. 240, 5, p. 1278-1288 11 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes

Koistinen, H. A., Galuska, D., Chibalin, A. V., Yang, J., Zierath, J. R., Holman, G. D. & Wallberg-Henriksson, H., 2003, In : Diabetes. 52, 5, p. 1066-1072 7 p.

Research output: Contribution to journalArticle

185 Citations (Scopus)

5-Formylcytosine can be a stable DNA modification in mammals

Bachman, M., Uribe-Lewis, S., Yang, X., Burgess, H. E., Iurlaro, M., Reik, W., Murrell, A. & Balasubramanian, S., 13 Aug 2015, In : Nature Chemical Biology. 11, 8, p. 555-557 3 p.

Research output: Contribution to journalArticle

Open Access
File
129 Citations (Scopus)
81 Downloads (Pure)

5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation

Uribe-Lewis, S., Carroll, T., Menon, S., Nicholson, A., Manasterski, P. J., Winton, D. J., Buczacki, S. J. A. & Murrell, A., 17 Jan 2020, In : Scientific Reports. 10, 1, 546.

Research output: Contribution to journalArticle

Open Access

5-Hydroxymethylcytosine is a predominantly stable DNA modification

Bachman, M., Uribe-Lewis, S., Yang, X., Williams, M., Murrell, A. & Balasubramanian, S., 1 Dec 2014, In : Nature Chemistry. 6, 12, p. 1049-1055 7 p.

Research output: Contribution to journalArticle

230 Citations (Scopus)

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

Uribe-lewis, S., Stark, R., Carroll, T., Dunning, M. J., Bachman, M., Ito, Y., Stojic, L., Halim, S., Vowler, S. L., Lynch, A. G., Delatte, B., De Bony, E. J., Colin, L., Defrance, M., Krueger, F., Silva, A., Ten Hoopen, R., Ibrahim, A. E., Fuks, F. & Murrell, A., 1 Apr 2015, In : Genome Biology. 16, 1, p. 1-15 15 p., 69.

Research output: Contribution to journalArticle

Open Access
38 Citations (Scopus)

6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: Synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor

Hodgson, D. M., Maxwell, C. R., Wisedale, R., Matthews, I. R., Carpenter, K. J., Dickenson, A. H. & Wonnacott, S., 2001, In : Journal of the Chemical Society: Perkin Transactions 1. 23, p. 3150-3158 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

A 6.5-Mb yeast artificial chromosome contig incorporating 33 DNA markers on the human X chromosome at Xq22

Vetrie, D., Kendall, E., Coffey, A., Hassock, S., Collins, J., Todd, C., Lehrach, H., Bobrow, M., Bentley, D. R. & Harris, A., 19 Jan 1994, In : Genomics. 19, 1, p. 42-47 6 p.

Research output: Contribution to journalArticle

A baseline estimate of population size for monitoring the Endangered Madagascar giant jumping rat Hypogeomys antimena

Young, R. P., Volahy, A. T., Bourou, R., Lewis, R., Durbin, J., Wright, T. J., Hounsome, T. D. & Fa, J. E., 2008, In : Oryx. 42, 4, p. 584-591 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation

Gebhard, S., 1 Dec 2012, In : Molecular Microbiology. 86, 6, p. 1295-1317

Research output: Contribution to journalArticle

56 Citations (Scopus)

Abdominal B-type Hox gene expression in Xenopus laevis

Lombardo, A. & Slack, J. M. W., 2001, In : Mechanisms of Development. 106, 1-2, p. 191-195 5 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Aberrant metal binding by prion protein in human prion disease

Wong, B. S., Chen, S. G., Colucci, M., Xie, Z. L., Pan, T., Liu, T., Li, R. L., Gambetti, P., Sy, M. S. & Brown, D. R., 2001, In : Journal of Neurochemistry. 78, 6, p. 1400-1408 9 p.

Research output: Contribution to journalArticle

178 Citations (Scopus)

Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

Blanco, S., Dietmann, S., Flores, J. V., Hussain, S., Kutter, C., Humphreys, P., Lukk, M., Lombard, P., Treps, L., Popis, M., Kellner, S., Holter, S. M., Garrett, L., Wurst, W., Becker, L., Klopstock, T., Fuchs, H., Gailus-Durner, V., Hrabe De Angelis, M., Karadottir, R. T. & 5 others, Helm, M., Ule, J., Gleeson, J. G., Odom, D. T. & Frye, M., 17 Sep 2014, In : The EMBO Journal. 33, 18, p. 2020-2039 20 p.

Research output: Contribution to journalArticle

Open Access
177 Citations (Scopus)
44 Downloads (Pure)

A bioimage informatics platform for high-throughput embryo phenotyping

Brown, J. M., Horner, N. R., Lawson, T. N., Fiegel, T., Greenaway, S., Morgan, H., Ring, N., Santos, L., Sneddon, D., Teboul, L., Vibert, J., Yaikhom, G., Westerberg, H. & Mallon, A-M., 1 Jan 2018, In : Briefings in Bioinformatics. 19, 1, p. 41-51 11 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

A boronic acid-based fluorescent hydrogel for monosaccharide detection

Xu, S., Sedgwick, A. C., Elfeky, S. A., Chen, W., Jones, A. S., Williams, G. T., Jenkins, A. T. A., Bull, S. D., Fossey, J. S. & James, T. D., 21 May 2019, In : Frontiers of Chemical Science and Engineering.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Absence of cell surface expression of human ACE leads to perinatal death

Michaud, A., Acharya, K. R., Masuyer, G., Quenech'du, N., Gribouval, O., Morinière, V., Gubler, M-C. & Corvol, P., Mar 2014, In : Human Molecular Genetics. 23, 6, p. 1479-1491 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A caffeine fix for human nuclear transfer?

Perry, A. C. F., Aug 2013, In : Nature Biotechnology. 31, 8, p. 717-719 3 p.

Research output: Contribution to journalArticle

A Cambrian–Ordovician Terrestrialization of Arachnids

Lozano-Fernandez, J., Tanner, A. R., Puttick, M. N., Vinther, J., Edgecombe, G. D. & Pisani, D., 11 Mar 2020, In : Frontiers in Genetics. 11, 182.

Research output: Contribution to journalArticle

Open Access

Acanthamoeba keratitis: The role of domestic tap water contamination in the United Kingdom

Kilvington, S., Gray, T., Dart, J., Morlet, N., Beeching, J. R., Frazer, D. G. & Matheson, M., 2004, In : Investigative Ophthalmology & Visual Science. 45, 1, p. 165-169 5 p.

Research output: Contribution to journalArticle

177 Citations (Scopus)

A cationic diode based on asymmetric nafion film deposits

He, D., Aaronson, B. D. B., Madrid, E., Fan, L., Doughty, J., Mathwig, K., Bond, A. M., Mckeown, N. B. & Marken, F., 29 Mar 2017, In : ACS Applied Materials and Interfaces. 9, 12, p. 11272-11278

Research output: Contribution to journalArticle

20 Citations (Scopus)

Accelerated evolution of nervous system genes in the origin of Homo sapiens

Dorus, S., Vallender, E. J., Evans, P. D., Anderson, J. R., Gilbert, S. L., Mahowald, M., Wyckoff, G. J., Malcom, C. M. & Lahn, B. T., 2004, In : Cell. 119, 7, p. 1027-1040 14 p.

Research output: Contribution to journalArticle

310 Citations (Scopus)

Accelerated molecular evolution of insect orthologues of ERG28/C14orf1: a link with ecdysteroid metabolism?

Veitia, R. A. & Hurst, L. D., 2001, In : Journal of Genetics. 80, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Accessing the mobile metagenome of the human gut microbiota

Jones, B. V. & Marchesi, J. R., Nov 2007, In : Molecular Biosystems. 3, 11, p. 749-758 10 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Accessory gene regulator (Agr) functionality in Staphylococcus aureus derived from lower respiratory tract infections

Gomes-Fernandes, M., Laabei, M., Pagan, N., Hidalgo, J., Molinos, S., Villar Hernandez, R., Domínguez-Villanueva, D., Jenkins, A. T. A., Lacoma, A. & Prat, C., 1 Apr 2017, In : PLoS ONE. 12, 4, e0175552.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Accumulation of eicosapolyenoic acids enhances sensitivity to abscisic acid and mitigates the effects of drought in transgenic arabidopsis thaliana

Yuan, X., Li, Y., Liu, S., Xia, F., Li, X. & Qi, B., 1 Apr 2014, In : Journal of Experimental Botany. 65, 6, p. 1637-1649 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Accumulation of hydroxycoumarins during post-harvest deterioration of tuberousroots of cassava (Manihot esculenta Crantz)

Buschmann, H., Rodriguez, M. X., Tohme, J. & Beeching, J. R., 2000, In : Annals of Botany. 86, 6, p. 1153-1160

Research output: Contribution to journalArticle

59 Citations (Scopus)

ACE-domain selectivity extends beyond direct interacting residues at the active site

Cozier, G., Lubbe, L., Sturrock, E. & Acharya, R., 17 Apr 2020, In : Biochemical Journal. 477, 7, p. 1241-1259 19 p.

Research output: Contribution to journalArticle

Open Access
File
3 Downloads (Pure)

ACE for all - a molecular perspective

Harrison, C. & Acharya, K. R., Sep 2014, In : Journal of Cell Communication and Signaling. 8, 3, p. 195-210

Research output: Contribution to journalArticle

15 Citations (Scopus)

Ace N-domain crystal

Acharya, R. & Sturrock, E. D., 30 Dec 2009, IPC No. A61K, Patent No. ZA200806312 (A)

Research output: Patent

A century of bias in genetics and evolution

Hurst, L., 12 Jun 2019, In : Heredity. 123, 1, p. 33-43 11 p.

Research output: Contribution to journalReview article

Open Access
File
24 Downloads (Pure)
8 Citations (Scopus)

ACE revisited: A new target for structure-based drug design

Acharya, K. R., Sturrock, E. D., Riordan, J. F. & Ehlers, M. R. W., 2003, In : Nature Reviews Drug Discovery. 2, 11, p. 891-902 12 p.

Research output: Contribution to journalArticle

220 Citations (Scopus)

A chromatin-independent role of polycomb-like 1 to stabilize p53 and promote cellular quiescence

Brien, G. L., Healy, E., Jerman, E., Conway, E., Fadda, E., O’Donovan, D., Krivtsov, A. V., Rice, A. M., Kearney, C. J., Flaus, A., McDade, S. S., Martin, S. J., McLysaght, A., O’Connell, D. J., Armstrong, S. A. & Bracken, A. P., 1 Nov 2015, In : Genes and Development. 29, 21, p. 2231-2243 13 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Acid phosphatases of Metarhizium anisopliae during infection of the tobacco hornworm Manduca sexta

Xia, Y. X., Clarkson, J. M. & Charnley, A. K., 2001, In : Archives of Microbiology. 176, 6, p. 427-434 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

A combined kinetic and modeling study of the catalytic center subsites of human angiogenin

Russo, N., Acharya, K. R., Vallee, B. L. & Shapiro, R., 23 Jan 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 2, p. 804-808 5 p.

Research output: Contribution to journalArticle

Open Access
53 Citations (Scopus)

A common trafficking route for GLUT4 in cardiomyocytes in response to insulin, contraction and energy-status signalling

Fazakerley, D. J., Lawrence, S. P., Lizunov, V. A., Cushman, S. W. & Holman, G. D., 1 Mar 2009, In : Journal of Cell Science. 122, 5, p. 727-734 8 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

A comparative bioinformatic analysis of C9orf72

Iyer, S., Acharya, K. R. & Subramanian, V., 19 Feb 2018, In : PeerJ. 6, 2, p. e4391 e4391.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

A comparative genomics study of Staphylococcus epidermidis from orthopedic device-related infections correlated with patient outcome

Post, V., Harris, L. G., Morgenstern, M., Mageiros, L., Hitchings, M. D., Méric, G., Pascoe, B., Sheppard, S. K., Richards, R. G. & Moriarty, T. F., 1 Oct 2017, In : Journal of Clinical Microbiology. 55, 10, p. 3089-3103 00881-17.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
112 Downloads (Pure)

A comparative study of Willaertia magna (free-living amoeba) from different geographic areas using whole-cell and small-subunit rRNA restriction fragment length polymorphisms

Kilvington, S., Stevens, C., Ebert, F., Michel, R. & Beeching, J. R., 1995, In : Journal of Protozoology Research. 5, p. 97-107

Research output: Contribution to journalArticle

A comparative test of a theory for the evolution of anisogamy

Randerson, J. P. & Hurst, L. D., 2001, In : Proceedings of the Royal Society B: Biological Sciences. 268, 1469, p. 879-884 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins

Allen, S. C., Acharya, K. R., Palmer, K. A., Shapiro, R., Vallee, B. L. & Scheraga, H. A., 1 Oct 1994, In : Journal of Protein Chemistry. 13, 7, p. 649-658 10 p.

Research output: Contribution to journalArticle