Research Output 1994 2020

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2020

A randomized controlled trial to reduce sedentary time in rheumatoid arthritis: Protocol and rationale of the Take a STAND for Health study

Pinto, A. J., Peçanha, T., Meireles, K., Benatti, F. B., Bonfiglioli, K., Lúcia de Sá Pinto, A., Lima, F. R., Pereira, R. M. R., Irigoyen, M. C. C., Turner, J., Kirwan, J. P., Owen, N., Dunstan, D. W., Roschel, H. & Gualano, B., 21 Jan 2020, (Accepted/In press) In : Trials.

Research output: Contribution to journalArticle

On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory Study Highlighting the Importance of Infant Food

Statelova, M., Goumas, K., Fotaki, N., Holm, R., Symillides, M., Reppas, C. & Vertzoni, M., 1 Jan 2020, In : AAPS Journal. 22, 1, 6.

Research output: Contribution to journalArticle

2019
2 Citations (Scopus)

19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids

Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.

Research output: Contribution to journalArticle

Open Access

1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues

Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Open Access
27 Downloads (Pure)
Open Access
File

Alpha-Synuclein Structure and Parkinson's Disease – Lessons and Emerging Principles

Meade, R., Fairlie, D. P. & Mason, J., 22 Jul 2019, In : Molecular Neurodegeneration. 14, 1, p. 1-14 14 p., 29.

Research output: Contribution to journalArticle

Open Access

Amyloid peptide β 1-42 induces integrin α IIb β 3 activation, platelet adhesion, and thrombus formation in a NADPH Oxidase-Dependent Manner

Abubaker, A. A., Vara, D., Visconte, C., Eggleston, I., Torti, M., Canobbio, I. & Pula, G., 14 Mar 2019, In : Oxidative Medicine and Cellular Longevity. 2019, p. 1-12 12 p., 1050476.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
2 Citations (Scopus)
24 Downloads (Pure)

A PNA-based Lab-on-PCB diagnostic platform for rapid and high sensitivity DNA quantification

Jolly, P., Rainbow, J., Regoutz, A., Estrela, P. & Moschou, D., 1 Jan 2019, In : Biosensors and Bioelectronics. 123, p. 244-250 7 p.

Research output: Contribution to journalArticle

Open Access
File
Peptide Nucleic Acids
Polychlorinated Biphenyls
Polychlorinated biphenyls
DNA
Biosensing Techniques
1 Citation (Scopus)

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(III)-based anion receptor

Hewitt, S., Ali, R., Mailhot, R., Antonen, C., Dodson, C. & Butler, S., 28 May 2019, In : Chemical Science. 10, 20, p. 5373-5381 9 p.

Research output: Contribution to journalArticle

Open Access

Biorelevant release testing of biodegradable microspheres intended for intra-articular administration

Magri, G., Selmin, F., Cilurzo, F. & Fotaki, N., 1 Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 115-122 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment

Monteiro, L. M., Löbenberg, R., Fotaki, N., Barros de Araujo, G. L., Cotrim, P. C. & Bou-Chacra, N. A., 1 Sep 2019, In : Journal of Global Antimicrobial Resistance. 18, p. 279-283 5 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
23 Downloads (Pure)
Open Access
File
5 Citations (Scopus)

Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, p. 1-5 5 p., 848.

Research output: Contribution to journalArticle

Open Access
4 Downloads (Pure)
Open Access
File
9 Citations (Scopus)
67 Downloads (Pure)
Open Access
File
Glutamate Dehydrogenase
Biosensing Techniques
Plasmodium falciparum
Field effect transistors
Biosensors

Development of a peptide-based fluorescent probe for biological heme monitoring

Newton, L. D., Pascu, S. I., Tyrrell, R. M. & Eggleston, I. M., 21 Jan 2019, In : Organic and Biomolecular Chemistry. 17, 3, p. 467-471 5 p.

Research output: Contribution to journalArticle

Open Access

Diagnosis and initial management in psoriatic arthritis: a qualitative study with patients

Dures, E., Bowen, C., Brooke, M., Lord, J., Tillett, W., McHugh, N. & Hewlett, S., 26 Aug 2019, In : Rheumatology Advances in Practice. 3, 2, rkz022.

Research output: Contribution to journalArticle

Open Access
Open Access
6 Downloads (Pure)

Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys

Flynn, S. M., Epperly, P. M., Davenport, A. T., Cami-Kobeci, G., Husbands, S. M., Ko, M. C. & Czoty, P. W., 10 Apr 2019, In : Neuropsychopharmacology. 44, 8, p. 1476-1484 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
12 Downloads (Pure)

Electrochemical Aptasensor using Optimized Surface Chemistry for the Detection of Mycobacterium tuberculosis Secreted Protein MPT64 in Human Serum

Sypabekova, M., Jolly, P., Estrela, P. & Kanayeva, D., 1 Jan 2019, In : Biosensors and Bioelectronics. 123, p. 141-151 11 p.

Research output: Contribution to journalArticle

Open Access
File
Surface chemistry
Adsorbents
Tuberculosis
Artificial Receptors
Proteins

Evaluation of the Economic Burden of Psoriatic Arthritis and the Relationship Between Functional Status and Healthcare Costs

McHugh, N., Maguire, Á., Handel, I., Tillett, W., Morris, J., Hawkins, N., Cavill, C., Korendowych, E. & Mughal, F., 31 Aug 2019, In : The Journal of Rheumatology. 46, 8, 190083.

Research output: Contribution to journalArticle

1 Citation (Scopus)
34 Downloads (Pure)

Excitation-energy-dependent molecular beacon detects early stage neurotoxic aβ aggregates in the presence of cortical neurons

Gulácsy, C. E., Meade, R., Catici, D. A. M., Soeller, C., Pantos, G. D., Jones, D. D., Alibhai, D., Jepson, M., Valev, V. K., Mason, J. M., Williams, R. J. & Pudney, C. R., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1240-1250 11 p.

Research output: Contribution to journalArticle

Open Access
File
19 Downloads (Pure)

Exposing the Interplay Between Enzyme Turnover, Protein Dynamics and the Membrane Environment in Monoamine Oxidase B

Jones, H. B. L., Crean, R. M., Mullen, A., Kendrick, E., Bull, S. D., Wells, S. A., Carbery, D. R., MacMillan, F., van der Kamp, M. W. & Pudney, C. R., 7 May 2019, In : Biochemistry. 58, 18, p. 2362-2372 11 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
12 Downloads (Pure)

Expression of Myxovirus-resistance Protein A: A Possible Marker of Muscle Disease Activity and Autoantibody Specificities in Juvenile Dermatomyositis

Soponkanaporn, S., Deakin, C. T., Schutz, P. W., Marshall, L. R., Yasin, S. A., Johnson, C. M., Sag, E., Tansley, S. L., McHugh, N. J., Wedderburn, L. R. & Jacques, T. S., 1 Jun 2019, In : Neuropathology and Applied Neurobiology. 45, 4, p. 410-420 11 p.

Research output: Contribution to journalArticle

Open Access
Myxovirus Resistance Proteins
Staphylococcal Protein A
Autoantibodies
Myositis
Muscles
2 Citations (Scopus)
26 Downloads (Pure)

Extracellular Electrophysiology in the Prostate Cancer Cell Model PC-3

Cabello, M., Ge, H., Aracil, C., Moschou, D., Estrela, P., Quero, J. M., Pascu, S. & Rocha, P., 1 Jan 2019, In : Sensors. 19, 1, 11 p., 139.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)

Fatigue in primary Sjögren’s syndrome (pSS) is associated with lower levels of proinflammatory cytokines: a validation study

UK Primary Sjögren’s Syndrome registry, 1 Nov 2019, In : Rheumatology International. 39, 11, p. 1867-1873 7 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups

Myositis Genetics Consortium (MYOGEN), 1 Jul 2019, In : Annals of the Rheumatic Diseases. 78, 7, p. 996-1002 7 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Frequency, mutual exclusivity and clinical associations of myositis autoantibodies in a combined European cohort of idiopathic inflammatory myopathy patients

Betteridge, Z., Tansley, S., Shaddick, G., Chinoy, H., Cooper, R. G., New, R. P., Lilleker, J. B., Vencovsky, J., Chazarain, L., Danko, K., Nagy-Vincze, M., Bodoki, L., Dastmalchi, M., Ekholm, L., Lundberg, I. E. & McHugh, N., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 48-55 8 p.

Research output: Contribution to journalArticle

Open Access

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

The European Vasculitis Genetics Consortium, 1 Dec 2019, In : Nature Communications. 10, 1, 5120.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Gold interdigitated triple-microelectrodes for label-free prognosticative aptasensing of prostate cancer biomarker in serum

Ibau, C., Md Arshad, K., Gopinath, S., Nuzaihan, M., Fathil, M. & Estrela, P., 1 Jul 2019, In : Biosensors and Bioelectronics. 136, p. 118-127 10 p.

Research output: Contribution to journalArticle

Highlights from the 2018 pharm sci AAPS annual meeting in Washington DC

Fotaki, N., Krämer, J. & Diaz, D., 1 Nov 2019, In : Dissolution Technologies. 26, 4, p. 38-45 8 p.

Research output: Contribution to journalArticle

4 Downloads (Pure)

Highly Water-Soluble Orotic Acid Nanocrystals Produced by High-Energy Milling

de Cássia Zaghi Compri, J., Andres Felli, V. M., Lourenço, F. R., Takatsuka, T., Fotaki, N., Löbenberg, R., Bou-Chacra, N. A. & Barros de Araujo, G. L., 1 May 2019, In : Journal of Pharmaceutical Sciences. 108, 5, p. 1848-1856 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)

Histological heterogeneity in a large clinical cohort of juvenile idiopathic inflammatory myopathy: analysis by myositis autoantibody and pathological features

UK Juvenile Dermatomyositis Research Group (UK-Ireland), 1 Aug 2019, In : Neuropathology and Applied Neurobiology. 45, 5, p. 495-512 18 p.

Research output: Contribution to journalArticle

Open Access

Identification of a novel autoantigen eukaryotic initiation factor 3 associated with polymyositis

Betteridge, Z., Chinoy, H., Vencovsky, J., Winer, J., Putchakayala, K., Ho, P., Lundberg, I., Danko, K., Cooper, R. & McHugh, N., 19 Aug 2019, (Accepted/In press) In : Rheumatology (Oxford, England).

Research output: Contribution to journalArticle

In-situ synthesis of 3D ultra-small gold augmented graphene hybrid for highly sensitive electrochemical binding capability

Taj, A., Shaheen, A., Xu, J., Estrela, P., Mujahid, A., Asim, T., Iqbal, Z., Khan, W. & Bajwa, S., 1 Oct 2019, In : Journal of Colloid and Interface Science. 553, p. 289-297 9 p.

Research output: Contribution to journalArticle

Label-Free Electrochemical Detection of S. Mutans Exploiting Commercially Fabricated Printed Circuit Board Sensing Electrodes

Dutta, G., Jallow, A., Paul, D. & Moschou, D., 30 Aug 2019, In : Micromachines. 10, 9, p. 1-9 9 p., 575.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
16 Downloads (Pure)

Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation

Gilburt, J., Girvan, P., Blagg, J., Ying, L. & Dodson, C., 14 Apr 2019, In : Chemical Science. 10, 14, p. 4069-4076 8 p.

Research output: Contribution to journalArticle

Open Access

Lipid metabolism links nutrient-exercise timing to insulin sensitivity in men classified as overweight or obese. Breakfast, exercise and metabolic health

Edinburgh, R., Bradley, H., Abdullah, N-F., Robinson, S., Chrzanowski-Smith, O., Walhin, J-P., Joanisse, S., Manolopoulos, K., Philp, A., Hengist, A., Chabowski, A., Brodsky, F., Koumanov, F., Betts, J., Thompson, D., Wallis, G. & Gonzalez, J., 19 Oct 2019, In : Journal of Clinical Endocrinology & Metabolism. p. 1-47 47 p., dgz104.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access
3 Citations (Scopus)

Long-lasting effects of methocinnamox on opioid self-administration in rhesus monkeys

Maguire, D. R., Gerak, L. R., Woods, J. H., Husbands, S., Disney, A. & France, C. P., 1 Jan 2019, In : Journal of Pharmacology and Experimental Therapeutics. 368, 1, p. 88-99 12 p., 252353.

Research output: Contribution to journalArticle

Open Access
File

Mechanism of human nail poration by high-repetition-rate, femtosecond laser ablation

Vanstone, S., Stone, J., Gordeev, S. & Guy, R., 1 Oct 2019, In : Drug Delivery and Translational Research. 9, 5, p. 956–967 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation

van Weverwijk, A., Koundouros, N., Iravani, M., Ashenden, M., Gao, Q., Poulogiannis, G., Jungwirth, U. & Isacke, C. M., 20 Jun 2019, In : Nature Communications. 10, 1, 2698.

Research output: Contribution to journalArticle

Open Access

Methocinnamox Produces Long-Lasting Antagonism of the Behavioral Effects of µ-Opioid Receptor Agonists but Not Prolonged Precipitated Withdrawal in Rats

Gerak, L. R., Minervini, V., Latham, E., Ghodrati, S., Lillis, K. V., Wooden, J., Disney, A., Husbands, S. M. & France, C. P., 1 Nov 2019, In : The Journal of pharmacology and experimental therapeutics. 371, 2, p. 507-516 10 p.

Research output: Contribution to journalArticle