Centre for Therapeutic Innovation

Research output

Research output per year 1978 2017 2018 2019 2020 2021 2022 2023 2024 2025

• 1692 Article
• 156 Review article
• 119 Poster
• 112 Abstract
• 509 More
  • 98 Chapter in a published conference proceeding
  • 85 Book chapter
  • 78 Paper
  • 48 Meeting abstract
  • 46 Comment/debate
  • 32 Editorial
  • 24 Letter
  • 20 Patent
  • 18 Conference article
  • 14 Other
  • 10 Other contribution
  • 9 Book
  • 6 Commissioned report
  • 5 Entry for encyclopedia/dictionary
  • 4 Other chapter contribution
  • 4 Preprint
  • 3 Book/Film/Article review
  • 2 Foreword/postscript
  • 1 Other report
  • 1 Special issue
  • 1 Working paper

Research output per year

Research output per year

Search results

• 2024

  AB1460 DEVELOPMENT STRATEGIES AND THEORETICAL UNDERPINNINGS OF SMARTPHONE APPS TO SUPPORT SELF-MANAGEMENT OF RHEUMATIC AND MUSCULOSKELETAL DISEASES: A SYSTEMATIC LITERATURE REVIEW

  Barnett, R., Clarke, C., Sengupta, R. & Rouse, P., 10 Jun 2024, p. 2092.1-2092.

  Research output: Contribution to conference › Abstract › peer-review

  • Self-Management 100%
  • Musculoskeletal Disease 100%
  • Healthcare Professional 30%
  • Behavior Change Technique 30%
  • Positive Health 20%

• POS0964 DYNAMIC PREDICTION OF PSORIATIC ARTHRITIS IN A COHORT OF PSORIASIS PATIENTS USING UK PRIMARY CARE ELECTRONIC HEALTH RECORDS.

  Rudge, A., Mchugh, N., Tillett, W. & Smith, T., 10 Jun 2024, p. 699.2-700.

  Research output: Contribution to conference › Abstract

  • Hazard Ratio 100%
  • Psoriasis 100%
  • Psoriatic Arthritis 100%
  • Confidence Interval 50%
  • Covariate 50%
• 2023

  Antibiotic-associated acute kidney injury among older adults: A case-crossover study

  Chinzowu, T. & Nishtala, P., 23 Apr 2023.

  Research output: Contribution to conference › Abstract › peer-review

  • Acute Kidney Failure 100%
  • Confidence Interval 27%
  • Odds Ratio 18%
  • Quinolone Derivative 18%
  • Sulfonamide 18%

• P170 Identifying predictors of axial spondyloarthritis flare onset using daily patient-reported data collected via a smartphone app

  Kypta-Vivanco, A., Barnett, R. & Sengupta, R., 24 Apr 2023, p. ii105. 1 p.

  Research output: Contribution to conference › Abstract

  Open Access

  • Spondylarthritis 100%
  • Rheumatic Disease 100%
  • Spondyloarthritis 100%
  • Behavior (Neuroscience) 100%
  • Anti-Inflammatory 66%
• 2022

  A novel fluorescent probe with high selectivity and sensitivity for quantification and imaging of cytosolic labile iron pool

  Hider, R. C., Reelfs, O., Ma, Y., Cilibrizzi, A. & Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Approximating blood as a shear-thinning Generalized Newtonian Fluid underestimates secondary flow, as quantified by the relative torque, in rotating domains

  Kelly, N., Gill, H. S., Cookson, A. & Fraser, K., 17 Mar 2022, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

• Blade design optimisation for the NeoVAD, a tiny Ventricular Assist Device for babies, using Computational Fluid Dynamics based Machine Learning

  Nissim, L., Karnik, S., Smith, P. A., Wang, Y. & Fraser, K., 17 Mar 2022, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

• Connecting the Intracellular Labile Ironome to Susceptibility of Skin Cells to Sunlight: a Powerful Approach Towards Personalised Sun Protection

  Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Exploiting the UVA-induced iron release for improving the efficiency of indoor and outdoor photodynamic therapy of skin cancer

  Beiki, D., Eggleston, I. & Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Exploiting the UVA-induced labile iron release to improve the efficiency of indoor and outdoor photodynamic therapy of skin cancer

  Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Investigating the therapeutic effects of different antioxidants in Friedreich’s ataxia

  Edzeamy, F. J., Gómez, A. V., Pourzand, C., Hider, R., McCarthy, R. & Anjomani-Virmouni, S., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Mitochondria-targeted iron chelators for prognosis, prevention and the therapy of mitochondrial iron overload disorders

  Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Patient and clinician experiences of remote cardiac rehabilitation during the COVID-19 pandemic: a qualitative study

  Springett, D., Gillison, F., Thompson, D., Augustine, D. X. & Peacock, O., 21 Nov 2022, p. A11-A12.

  Research output: Contribution to conference › Abstract

  • Physical Activity 100%
  • Qualitative Study 100%
  • Heart Rehabilitation 100%
  • Pandemic 100%
  • Open-Ended Question 50%

• POS1077 LARGE JOINT INVOLVEMENT AND SUBSTANTIAL DISEASE BURDEN IN PATIENTS WITH OLIGOARTICULAR AND POLYARTICULAR PSORIATIC ARTHRITIS IN THE MULTINATIONAL UPLIFT SURVEY

  Tillett, W., Ogdie, A., Richette, P., Gottlieb, A., Jardon, S., Richter, S., Flower, A. & Merola, J., 1 Jul 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Targeting iron in psoriatic skin, a new approach for topical therapy of plaque psoriasis

  Pourzand, C., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Targeting iron in psoriatic skin, a novel approach for topical therapy of plaque psoriasis

  Pourzand, C., Wardhani, R. A. P., Zhou, Z., Cilibrizzi, A. & Hider, R., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• THE THERAPEUTIC EFFECTS OF DIFFERENT ANTIOXIDANTS IN FRIEDREICH’S ATAXIA

  Edzeamy, F. J., Gómez, A. V., Pourzand, C., Hider, R., McCarthy, R. & Anjomani-Virmouni, S., 2022.

  Research output: Contribution to conference › Abstract › peer-review

• Towards complete Fluid Structure Interaction simulations for assessment of possible blood damage risk in the Realheart®, a novel Total Artificial Heart

  Bornoff, J., Kelly, N., Najar, A., Cookson, A., Perkins, I. L. & Fraser, K., 17 Mar 2022, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

• Understanding treatment of pain during COVID pandemic - a wastewater-based epidemiology approach

  Ceolotto, N., Xu, L., Jagadeesan, K. K., Barnett, J., Standerwick, R., Barden, R. & Kasprzyk-Hordern, B., 11 Oct 2022.

  Research output: Contribution to conference › Abstract

• Upadacitinib versus adalimumab on routine assessment of patient index data 3 (rapid3) in patients with psoriatic arthritis.

  Coates, L., Kavanaugh, A., Mcdearmon-Blondell, E., Mandelin, A., Gao, T. & Tillett, W., 1 Jul 2022.

  Research output: Contribution to conference › Abstract › peer-review
• 2021

  Development of a finite element model of ankle injury and stability

  Chen, H., Gulati, A., Mangwani, J., Brockett, C. & Pegg, E., 14 Sept 2021.

  Research output: Contribution to conference › Abstract › peer-review

  • Finite Element Modeling 100%
  • Biodynamics 100%
  • Utah 100%
  • Materials Property 66%
  • Biomechanics 33%

• Harnessing the UVA-induced redox active labile iron release to improve the efficiency of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) of skin cancer

  Pourzand, C., 2021.

  Research output: Contribution to conference › Abstract › peer-review

• IMPROVING THE ACCURACY AND EFFICIENCY OF POSITIVE DISPLACEMENT ARTIFICAL HEART SIMULATIONS USING A FLUID-STRUCTURE INTERACTION APPROACH

  Bornoff, J., Nilsson, L., Gill, H. S., Najar, A., Perkins, I. L., Cookson, A. & Fraser, K., 10 Sept 2021.

  Research output: Contribution to conference › Abstract

  • Fluid-Structure Interaction 100%
  • Positive Displacement 100%
  • Artificial Heart 100%
  • Modeling Strategy 66%
  • Computational Fluid Dynamics 33%

• Improving the efficiency of ALA-PDT of skin cells using indoor and outdoor UVA-based light fractionation approach

  Pourzand, C., 2021.

  Research output: Contribution to conference › Abstract › peer-review

• Machine Learning based blade design optimisation of the NeoVAD

  Nissim, L., Karnik, S., Smith, P. A., Wang, Y. & Fraser, K., 22 Oct 2021, (Acceptance date).

  Research output: Contribution to conference › Abstract

  • Design Optimization 100%
  • Surrogate Model 100%
  • Blades Design 100%
  • Learning System 100%
  • Computational Fluid Dynamics 66%

• Peptide-targeted systems for Photodynamic therapy’

  Wang, D., MacRobert, S., Pourzand, C. & Eggleston, I., 2021.

  Research output: Contribution to conference › Abstract › peer-review

• Synthesis and Evaluation of Peptide-Targeted Systems for Photodynamic Therapy (PDT)

  Wang, D., MacRobert, S., Pourzand, C. & Eggleston, I., 2021.

  Research output: Contribution to conference › Abstract › peer-review

• The neuroprotective potential of novel mitochondria-targeted iron chelators against oxidative cell death in a cell model of Parkinson’s disease

  Pourzand, C., Reelfs, O., Chen, Y.-L., Abbate, V. & Hider, R. C., Oct 2021.

  Research output: Contribution to conference › Abstract › peer-review

• Theoretical reduction in the anticholinergic burden in older adults with dementia in New Zealand

  Nishtala, P., 25 Jun 2021.

  Research output: Contribution to conference › Abstract › peer-review

  • Cholinergic Receptor Blocking Agent 100%
  • Comorbidity 100%
  • Prevalence 20%
  • Adverse Outcome 20%

• Towards Accurate and Efficient Simulations of Positive Displacement Artifical Hearts

  Bornoff, J., Singh, N., Carnarius, M., Gill, H. S., Najar, A., Perkins, I. L., Cookson, A. & Fraser, K., 14 Jul 2021.

  Research output: Contribution to conference › Abstract

  • Structure Interaction 100%
  • Computational Fluid Dynamics 100%
  • Driven Flow 100%
  • Computation Time 100%
  • Refined Mesh 100%

• Understanding treatment of pain during COVID pandemic – a wastewater-based epidemiology approach

  Ceolotto, N., Kasprzyk-Hordern, B., Xu, L., Jagadeesan, K. K., Standerwick, R., Barden, R. & Barnett, J., 27 Sept 2021.

  Research output: Contribution to conference › Abstract

  • Cohort Effect 100%
  • Treatment of Pain 100%
  • COVID-19 100%
  • Drug 100%
  • Metabolite 33%

• Wastewater-Based Epidemiology for Monitoring Community Derived Antibiotic and Resistant Genes

  Sims, N., Kannan, A., Holton, E., Jagadeesan, K. K., Barden, R. & Kasprzyk-Hordern, B., 6 May 2021.

  Research output: Contribution to conference › Abstract › peer-review

  • Antimicrobial Resistance 100%
  • Antibiotic Resistance 100%
  • Wastewater-Based Epidemiology 100%
  • Metabolite 100%
  • Antibiotics 80%
• 2020

  AB1241 EVALUATION OF A PATIENT COMPLETED DISEASE FLARE QUESTIONNAIRE IN PSORIATIC DISEASE

  Helliwell, P., Tillett, W., Waxman, R., Coates, L., Fitzgerald, O., Packham, J. & Mchugh, N., 1 May 2020.

  Research output: Contribution to conference › Abstract › peer-review

• Introduction on the role of iron and hepcidin in the process of cells and wound healing

  Pourzand, C., 2020.

  Research output: Contribution to conference › Abstract › peer-review

• Investigating the Impact of Age on Oral Montelukast Pharmacokinetics Using in vitro dissolution and PBPK Modeling

  Guimaraes Sa Correia, M., Somville, P., Vertzoni, M. & Fotaki, N., 2020.

  Research output: Contribution to conference › Abstract › peer-review

• Nose to Brain Drug Delivery of Aerosolized Nanoparticles

  Maaz, A., De Bank, P., Blagbrough, I. & Price, R., 2020.

  Research output: Contribution to conference › Abstract

• TightRight : augmenting screwdrivers to reduce bone stripping rates and optimise tightness when inserting non-locking screws

  Fletcher, J., Neumann, V., Silva-Henao, J., Mys, K., Panagiotopoulou, V., Verschueren, A., Gueorguiev, B., Richards, R. G., Whitehouse, M., Preatoni, E. & Gill, R., Jan 2020, (Acceptance date). 1 p.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

  File

  • Surgeon 100%
  • Implant 100%
  • Artificial Bone 100%
  • Student T Test 33%
  • Orthopedic Surgeon 33%
  45 Downloads (Pure)
• 2019

  A computational model to predict the onset of secondary flows of blood in a cone & plate rheometer

  Kelly, N., Jelliffe, D., Gill, H., Fraser, K. & Cookson, A., 12 Jun 2019, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

• Addressing Human Clinical Inter- and Intra Subject Variability of Lipophilic Compounds Using TIM-1 Dynamic Gastrointestinal Model

  Tomaszewska, I., Smith , K. L., Rahman, S., Sarcevica, I., Wanigaratne , S., Harper , A., Young, S. L., Effinger, A., Fotaki, N., Clear , N., Clayton, N. & McAllister, M., 2019.

  Research output: Contribution to conference › Abstract › peer-review

• Evaluating Food Effects on Oral Drug Absorption in Infants: An Exploratory Study in Healthy Adults.

  Statelova, M., Goumas, K., Fotaki, N., Holm, R., Symillides, M., Reppas, C. & Vertzoni, M., 2019.

  Research output: Contribution to conference › Abstract › peer-review

• EXPERIMENTAL AND NUMERICAL ANALYSIS OF THE PRIMARY-SECONDARY FLOW TRANSITION OF WHOLE BLOOD ANALOGUES IN A ROTATIONAL RHEOMETER

  Kelly, N., Gill, R., Cookson, A. & Fraser, K., 29 Aug 2019.

  Research output: Contribution to conference › Abstract › peer-review

• Investigating the Impact of Crohn's Disease on Oral Budesonide Pharmacokinetics Using In Vitro Dissolution Testing and PBPK Modeling

  Effinger, A., O'Driscoll, C. M., McAllister, M. & Fotaki, N., 2019.

  Research output: Contribution to conference › Abstract › peer-review

• NORMAL FLUID STRESSES IN ROTARY VENTRICULAR ASSIST DEVICES

  Khoo, D. P. Y., Cookson, A., Gill, R. & Fraser, K., 29 Aug 2019.

  Research output: Contribution to conference › Abstract › peer-review

• Prediction of the Effect of Co-administration of Food with Granules in Adults and Infants Based on Biorelevant Dissolution Testing

  Guimaraes Sa Correia, M., Vertzoni, M. & Fotaki, N., 2019.

  Research output: Contribution to conference › Abstract › peer-review

• Radiopaque polyethylenes to aid surgical device positioning and patient follow up

  Hossein Zadeh Zaribaf, F., Gill, R. & Pegg, E., 2019, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

  • High Molecular Weight Polyethylene 100%
  • Radiopaque 100%
  • Polyethylene 100%
  • Ultrahigh Molecular Weight Polyethylenes 100%
  • Anterior Cruciate Ligament 100%

• Real-time multidimensional feedback from wearable physical activity monitors supports positive behaviour change in inactive adults.

  Western, M., Standage, M., Peacock, O. & Thompson, D., 2019, (Unpublished).

  Research output: Contribution to conference › Abstract › peer-review

  • Physical Activity 100%
  • Self-Efficacy 20%
  • Analysis of Covariance 10%
  • Autonomy 10%
  • Semistructured Interview 10%

• Reliability of Three Different Methods for Assessing Amputee Residuum Shape and Volume

  Bilzon, J., Canepa Talamas, D., Young, M., Twiste, M., Dhokia, V. & Seminati, E., Apr 2019, (Acceptance date).

  Research output: Contribution to conference › Abstract › peer-review

• Targeting the UVA-induced labile iron release to improve the effectiveness of topical aminolevulinate-based photodynamic therapy of skin cells

  Beiki, D., Reelfs, O., Eggleston, I. & Pourzand, C., 30 Aug 2019.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access

• The cytoprotection of novel mitochondria-targeted iron chelators against UVA- and hydrogen peroxide-induced oxidative cell death in Friedreich’s ataxia fibroblasts

  Reelfs, O., Abbate, V., Cilibrizzi, A., Hider, R. C. & Pourzand, C., 21 Jun 2019.

  Research output: Contribution to conference › Abstract › peer-review

• The cytoprotective potential of novel mitochondria-targeted iron chelators against sunlight and H2O2-mediated oxidative cell death in Friedreich’s ataxia fibroblasts

  Reelfs, O., Cilibrizzi, A., Abbate, V., Hider, R. C. & Pourzand, C., 30 Aug 2019.

  Research output: Contribution to conference › Abstract › peer-review

  Open Access