Research Output

2020

Accelerating the development of novel technologies and tools for the subcutaneous delivery of biotherapeutics

Collins, D. S., Sanchez-Felix, M., Badkar, A. V. & Mrsny, R., 24 Feb 2020, In : Journal of Controlled Release.

Research output: Contribution to journalArticle

Open Access

A randomized controlled trial to reduce sedentary time in rheumatoid arthritis: Protocol and rationale of the Take a STAND for Health study

Pinto, A. J., Peçanha, T., Meireles, K., Benatti, F. B., Bonfiglioli, K., Lúcia de Sá Pinto, A., Lima, F. R., Pereira, R. M. R., Irigoyen, M. C. C., Turner, J., Kirwan, J. P., Owen, N., Dunstan, D. W., Roschel, H. & Gualano, B., 12 Feb 2020, In : Trials. 21, 1, 171.

Research output: Contribution to journalArticle

Open Access

Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Hypromellose (HPMC)

Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 2020, In : AAPS Journal. 22, 49.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Biopharmaceutical understanding of excipient variability on drug apparent solubility based on drug physicochemical properties. Case study: Superdisintegrants

Zarmpi, P., Flanagan, T., Meehan, E., Mann, J. & Fotaki, N., 11 Feb 2020, In : AAPS Journal. 22, 2, 46.

Research output: Contribution to journalArticle

Open Access

Cholix Protein Domain I Functions as a Carrier Element for Efficient Apical to Basal Epithelial Transcytosis

Taverner, A., Mackay, J., Laurent, F., Hunter, T., Liu, K., Mangat, K., Song, L., Seto, E., Postlethwaite, S., Alam, A., Chandalia, A., Seung, M., Saberi, M., Feng, W. & Mrsny, R., 13 Jan 2020, In : Tissue Barriers. 1710429.

Research output: Contribution to journalArticle

Open Access

Coupling Computational and Intracellular Screening and Selection Towards Co-compatible cJun and cFos Antagonists

Lathbridge, A., Michalowska, A. & Mason, J., 4 Feb 2020, In : Biochemistry. 59, 4, p. 530-540

Research output: Contribution to journalArticle

Open Access
File
9 Downloads (Pure)

Development of an Aerosol Dose Collection Apparatus for In Vitro Dissolution Measurements of Orally Inhaled Drug Products

Price, R., Shur, J., Ganley, W., Farias, G., Fotaki, N., Conti, D. S., Delvadia, R., Absar, M., Saluja, B. & Lee, S., 1 Mar 2020, In : AAPS Journal. 22, 2, 47.

Research output: Contribution to journalArticle

Open Access
2 Downloads (Pure)

Investigation of drug partition kinetics to fat in simulated fed state gastric conditions based on drug properties

Baxevanis, F., Zarmpi, P., Kuiper, J. & Fotaki, N., 12 Feb 2020, In : European Journal of Pharmaceutical Sciences. 105263.

Research output: Contribution to journalArticle

Lymphocytopenia

Brown, F. & Turner, J., 1 Jan 2020, Encyclopedia of Behavioral Medicine. Springer

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Lymphocytosis

Brown, F. & Turner, J., 21 Jan 2020, Encyclopedia of Behavioural Medicine. Springer, 1 p.

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Minimising Tibial Fracture after Unicompartmental Knee Replacement: A Probabilistic Finite Element Study

Pegg, E., Walter, J., D'Lima, D. D., Fregly, B. J., Gill, R. & Murray, D. W., 1 Mar 2020, In : Clinical Biomechanics. 73, p. 46-54 9 p.

Research output: Contribution to journalArticle

On the Design of Food Effect Studies in Adults for Extrapolating Oral Drug Absorption Data to Infants: an Exploratory Study Highlighting the Importance of Infant Food

Statelova, M., Goumas, K., Fotaki, N., Holm, R., Symillides, M., Reppas, C. & Vertzoni, M., 1 Jan 2020, In : AAPS Journal. 22, 1, 6.

Research output: Contribution to journalArticle

OREX-1019: a novel treatment for opioid use disorder and relapse prevention

Maguire, D., Gerak, L., Cami-Kobeci, G., Husbands, S., France, C., Belli, B. & Flynn, P., 1 Feb 2020, In : Journal of Pharmacology and Experimental Therapeutics. 372, 2, p. 205-215

Research output: Contribution to journalArticle

Patient views of the role of wearable technology to enhance cardiac rehabilitation

Lauber, K., Wort, G., Gillison, F., Thompson, D., Augustine, D. & Peacock, O., 16 Jan 2020.

Research output: Contribution to conferencePoster

Peptide cargo tunes a network of correlated motions in human leukocyte antigens

Hopkins, J. R., Crean, R. M., Catici, D. A. M., Sewell, A. K., Arcus, V. L., Van der Kamp, M. W., Cole, D. K. & Pudney, C. R., 5 Mar 2020, In : FEBS Journal.

Research output: Contribution to journalArticle

Rapid and on-site simultaneous electrochemical detection of copper, lead and mercury in the Amazon river

Bernalte, E., Arévalo, S., Pérez-Taborda, J., Wenk, J., Estrela, P., Avila, A. & Di Lorenzo, M., 15 Mar 2020, In : Sensors and Actuators B: Chemical. 307, 127620.

Research output: Contribution to journalArticle

Open Access
2 Downloads (Pure)

TightRight : augmenting screwdrivers to reduce bone stripping rates and optimise tightness when inserting non-locking screws

Fletcher, J., Neumann, V., Silva-Henao, J., Mys, K., Panagiotopoulou, V., Verschueren, A., Gueorguiev, B., Richards, R. G., Whitehouse, M., Preatoni, E. & Gill, R., Jan 2020, (Accepted/In press). 1 p.

Research output: Contribution to conferenceAbstract

Open Access
File
3 Downloads (Pure)
2019

19F and 1H quantitative-NMR spectroscopic analysis of fluorinated third-generation synthetic cannabinoids

Naqi, H., Woodman, T., Husbands, S. & Blagbrough, I., 28 Jun 2019, In : Analytical Methods. 11, 24, p. 3090-3100 11 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

1H quantitative NMR and UHPLC-MS analysis of seized MDMA/NPS mixtures and tablets from night-club venues

Naqi, H., Husbands, S. & Blagbrough, I., 7 Oct 2019, In : Analytical Methods. 11, 37, p. 4795-4807 13 p.

Research output: Contribution to journalArticle

Open Access
Open Access
2 Citations (Scopus)
31 Downloads (Pure)

Alpha-Synuclein Structure and Parkinson's Disease – Lessons and Emerging Principles

Meade, R., Fairlie, D. P. & Mason, J., 22 Jul 2019, In : Molecular Neurodegeneration. 14, 1, p. 1-14 14 p., 29.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
1 Citation (Scopus)

Amyloid peptide β 1-42 induces integrin α IIb β 3 activation, platelet adhesion, and thrombus formation in a NADPH Oxidase-Dependent Manner

Abubaker, A. A., Vara, D., Visconte, C., Eggleston, I., Torti, M., Canobbio, I. & Pula, G., 14 Mar 2019, In : Oxidative Medicine and Cellular Longevity. 2019, p. 1-12 12 p., 1050476.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
1 Citation (Scopus)

A PNA-based Lab-on-PCB diagnostic platform for rapid and high sensitivity DNA quantification

Jolly, P., Rainbow, J., Regoutz, A., Estrela, P. & Moschou, D., 1 Jan 2019, In : Biosensors and Bioelectronics. 123, p. 244-250 7 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
34 Downloads (Pure)

Application of the relationship between pharmacokinetics and pharmacodynamics in drug development and therapeutic equivalence: a PEARRL review

Loisios-Konstantinidis, I., Paraiso, R. L. M., Fotaki, N., McAllister, M., Cristofoletti, R. & Dressman, J., 1 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 699-723 25 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
1 Downloads (Pure)

A simple, robust, universal assay for real-time enzyme monitoring by signalling changes in nucleoside phosphate anion concentration using a europium(III)-based anion receptor

Hewitt, S., Ali, R., Mailhot, R., Antonen, C., Dodson, C. & Butler, S., 28 May 2019, In : Chemical Science. 10, 20, p. 5373-5381 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Autoantibodies in connective tissuedisease

Mulhearn, B., Tansley, S. L. & McHugh, N. J., 14 Dec 2019, In : Best Practice and Research Clinical Rheumatology . 101462.

Research output: Contribution to journalReview article

Autophagy: Multiple Mechanisms to Protect Skin from Ultraviolet Radiation-Driven Photoaging

Mei, W., Pourzand, C., Xia, L. & Zhong, J. L., 13 Dec 2019, In : Oxidative Medicine and Cellular Longevity. 2019, 14 p., 8135985.

Research output: Contribution to journalReview article

Open Access

Biopharmaceutical considerations in paediatrics with a view to the evaluation of orally administered drug products – a PEARRL review.

Guimarães, M., Statelova, M., Holm, R., Reppas, C., Symilllides, M., Vertzoni, M. & Fotaki, N., 30 Apr 2019, In : Journal of Pharmacy and Pharmacology. 71, 4, p. 603-642 40 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
2 Downloads (Pure)

Biorelevant release testing of biodegradable microspheres intended for intra-articular administration

Magri, G., Selmin, F., Cilurzo, F. & Fotaki, N., 1 Jun 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 139, p. 115-122 8 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
3 Citations (Scopus)

Challenges in the Design of Lab-on-PCB Platforms

Moschou, D., 16 Jan 2019.

Research output: Contribution to conferencePaper

Co-delivery of buparvaquone and polymyxin B in a nanostructured lipid carrier for leishmaniasis treatment

Monteiro, L. M., Löbenberg, R., Fotaki, N., Barros de Araujo, G. L., Cotrim, P. C. & Bou-Chacra, N. A., 1 Sep 2019, In : Journal of Global Antimicrobial Resistance. 18, p. 279-283 5 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
30 Downloads (Pure)

Comparison of Three Immunoassays for the Detection of Myositis Specific Antibodies

Mahler, M., Betteridge, Z., Bentow, C., Richards, M., Seaman, A., Chinoy, H. & McHugh, N., 30 Apr 2019, In : Frontiers in Immunology. 10, p. 1-5 5 p., 848.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Correction to: Important Treatment Outcomes for Patients with Psoriatic Arthritis: A Multisite Qualitative Study

PROMPT Study Group, 1 Aug 2019, In : The patient. 12, 4, p. 437 1 p.

Research output: Contribution to journalComment/debate

Open Access

Cytomegalovirus

Turner, J., 13 Dec 2019, Encyclopedia of Behavioral Medicine. New York, U. S. A.: Springer

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Open Access
File
11 Citations (Scopus)
77 Downloads (Pure)

Development of a peptide-based fluorescent probe for biological heme monitoring

Newton, L. D., Pascu, S. I., Tyrrell, R. M. & Eggleston, I. M., 21 Jan 2019, In : Organic and Biomolecular Chemistry. 17, 3, p. 467-471 5 p.

Research output: Contribution to journalArticle

Open Access

Diagnosis and initial management in psoriatic arthritis: a qualitative study with patients

Dures, E., Bowen, C., Brooke, M., Lord, J., Tillett, W., McHugh, N. & Hewlett, S., 26 Aug 2019, In : Rheumatology Advances in Practice. 3, 2, rkz022.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access