Centre for Therapeutic Innovation

Projects

Projects per year 1997 2017 2018 2022 2024 2027

• 6 Not started
• 21 Active
• 107 Finished

Projects per year

Search results

• Active

  Bath Beacon for Managing Antimicrobial Resistance in a Changing World

  Byrnes, N. (Researcher), Silvester, R. (CoI), Cross, G. (CoI), Weightman, A. J. (CoI), Kasprzyk-Hordern, B. (PI) & Jones, D. L. (PI)

  5/12/24 → 28/02/26

  Project: Research-related funding

  • Antibiotic Resistance 100%
  • Antimicrobial Resistance 100%

• EPSRC IAA Open Call: Bridging the Gap in Realising the Biomedical Impact of NIR Emitting Chemicals

  Pascu, S. (PI) & Green, M. (Researcher)

  Engineering and Physical Sciences Research Council

  15/08/24 → 31/03/25

  Project: Research council

• Augmenting Follow-up of Joint Replacement Patients

  Pegg, E. (CoI), Şimşek, Ö. (CoI) & Gill, R. (PI)

  1/08/24 → 31/05/25

  Project: Research-related funding

  • Joint Replacement 100%

• Transforming the use of Ansys simulation software within engineering curricula at the University of Bath

  Pegg, E. (PI), Fraser, K. (CoPI), Chen, Y. (CoI), Mohammadi, A. (CoI), Pigeon, M. (CoI), Williams, D. (CoI) & Cayzer, S. (CoI)

  20/06/24 → 1/10/25

  Project: UK industry

  • Simulation Software 100%
  • Engineering 100%
  • Engineering Curriculum 100%
  • Engineering Analysis 100%
  • Engineering Problem 100%

• Trueview system for safer spinal surgery

  Gill, R. (PI)

  Innovate UK, Innovate UK Business Connect

  1/06/24 → 28/02/26

  Project: Central government, health and local authorities

• Do lipid droplets promote aggressive medulloblastoma tumour growth and if, so, can we do anything about it?

  Niklison Chirou, M. (PI)

  The Academy of Medical Sciences

  15/04/24 → 14/04/26

  Project: UK charity

• Entrepreneur in Residence

  Ward, S. (PI), Eccleston, C. (CoI), Gill, R. (CoI) & Larijani, B. (CoI)

  The Royal Society

  8/01/24 → 8/01/26

  Project: Research council

• Dementia and serious outcomes: top up funding for HES and SES data

  McGrogan, A. (PI)

  1/11/23 → 31/03/25

  Project: Other

• Developing Artificial Intelligence Solutions to Improve Diagnosis and Risk Stratification in Acute Pulmonary Embolism and Chronic Thrombo-Embolic Pulmonary Hypertension

  Cookson, A. (PI) & Gillison, F. (CoI)

  National Institute for Health Research

  1/07/23 → 31/12/25

  Project: Central government, health and local authorities

  • Acute Pulmonary Embolism 100%
  • Chronic Thromboembolic Pulmonary Hypertension 100%
  • Risk Stratification 100%
  • Pulmonary Embolism 86%
  • Cost-Effectiveness Analysis 34%

• Functional roles of presynaptic opioid receptors

  Bailey, C. (PI), Sambrook, M. (Researcher) & Williams, R. (CoI)

  1/10/22 → 30/09/26

  Project: Research council

  • Opiate Receptor 100%

• GW4-MRC DTP project collaboration

  Jungwirth, U. (PI)

  1/10/22 → 30/09/26

  Project: UK industry

• How fibroblasts and azathioprine prepare the soil for cutaneous squamous cell carcinoma

  Jungwirth, U. (PI)

  1/07/22 → 30/06/25

  Project: UK charity

• 'Opioid overdose deaths: Understanding the lethal interactions between benzodiazepines and opioids to develop new harm reduction strategies’

  Bailey, C. (PI)

  1/07/22 → 30/06/25

  Project: Research council

  • Medical Research 100%
  • Research Councils 100%
  • Benzodiazepine Derivative 100%
  • Harm Reduction 100%
  • Opioid Overdose 100%

• High impact chronic pain and UK biobank: presentation, transitions and targets for intervention

  van den Windt, D. (PI), Fisher, E. (CoI), Eccleston, C. (CoI), Keogh, E. (CoI) & Ehrhardt, B. (Researcher)

  1/06/22 → 2/06/25

  Project: Research-related funding

  • UK Biobank 100%
  • Chronic Pain 100%
  • Medical Research 100%

• Lipid metabolism a new target for medulloblastoma tumours?

  Niklison Chirou, M. (PI)

  Children's Cancer and Leukaemia Group

  10/01/22 → 9/01/26

  Project: UK charity

• Novel biomarkers in Juvenile Dermatomyositis

  Tansley, S. (PI) & McHugh, N. (CoI)

  1/01/22 → 31/03/25

  Project: Other

• ARUK Centre Renewal

  Bilzon, J. (PI), McKay, C. (CoI), Stokes, K. (CoI) & Thompson, D. (CoI)

  Versus Arthritis

  7/01/18 → 6/04/25

  Project: UK charity

  • Quality of Life 100%
  • Systematic Review 100%
  • Meta-Analysis 100%
  • Life Satisfaction 100%
  • Lifespan 100%

• Establishment of an animal-free three dimensional model to investigate key signaling pathways

  Munoz-Descalzo, S. (PI) & Tosh, D. (CoI)

  13/07/16 → …

  Project: Research-related funding

  • Triage 100%
  • Doctor of Philosophy 100%
  • Cell Signaling Pathway 100%
  • Signaling Pathway 100%
  • Dimensional Model 100%

• Myocardial Infarction Project

  Gill, R. (PI), Fraser, K. (CoI) & Cookson, A. (CoI)

  1/12/15 → …

  Project: Research-related funding

  • Heart Infarction 100%
  • Pig 46%
  • Heart Muscle Injury 33%
  • Heart Ventricle Remodeling 33%
  • Congestive Heart Failure 33%

• The Assessment of Structural Damage in Psoriatic Arthritis

  Tillett, W. (PI)

  1/05/14 → …

  Project: Central government, health and local authorities

  • Psoriatic Arthritis 100%
  • Tumor Necrosis 33%
  • Observational Study 33%
  • Disease Modifying Antirheumatic Drug 33%
  • Tumor Necrosis Factor 33%

• Synthesis of novel beta-turn mimics

  Eggleston, I. (PI)

  1/10/97 → …

  Project: Other

  • Beta Turn 100%
• Not started

  AMS - TRPV1 and cancer pain

  Carter, E. (PI)

  The Academy of Medical Sciences

  1/06/25 → 31/05/27

  Project: UK charity

• Phase 4

  Hattam, L. (Researcher), Georgiou, F. (Researcher), Pryer, T. (PI) & Nunes, M. (PI)

  Project: University consultancy

• The Impact of Biologic and Targeted Synthetic Disease Modifying Drugs in Psoriatic Arthritis

  Tillett, W. (PI)

  Project: UK industry

  • Psoriatic Arthritis 100%
  • Placebo 34%
  • Disease Activity 29%
  • Guselkumab 23%
  • Psoriasis 21%

• Dementia and serious health outcomes: a cohort and case control study investigating psychological distress as a risk factor

  McGrogan, A. (PI), Welsh, T. J. (CoI) & Jarvis, A. (Researcher)

  Project: Other

  • Health Outcomes 100%
  • Case-Control Study 100%

• Harnessing CRISPR/Cas9 technology to develop new models of Alzheimer's disease

  Subramanian, V. (PI)

  Project: Research-related funding

  • Alzheimer's Disease 100%

• MITIGATE: HUMAN INNERVATED, VASCULARIZED, AND IMMUNIZED TUMOURS-ON-CHIP AS SURROGATES FOR ANIMAL TESTING

  Larijani, B. (CoPI), Carter, E. (CoPI), Estrela, P. (CoPI) & Ferrer, A. (PI)

  Project: EU Commission

  • Animal Testing 100%
  • Neoplasm 100%
  • Malignant Neoplasm 100%
  • Wellbeing 100%
  • Immunocompetent Cell 100%
• Finished

  X-ray diffraction for lattice strain mapping of auxetic structure fillet radii

  Lunt, A. (PI), Rogers, B. (CoI), Dhokia, V. (CoI), Pegg, E. (CoI), Vo, N. (CoI) & Kalaiselvan, T. (CoI)

  14/02/25 → 18/02/25

  Project: Research-related funding

• An interpretable, reliable machine learning solution to classify single molecule fluorescence traces

  Dodson, C. (PI) & Walker, B. (PI)

  1/08/24 → 15/11/24

  Project: Research-related funding

• Phase 3

  Hattam, L. (Researcher), Georgiou, F. (Researcher), Pryer, T. (PI) & Nunes, M. (PI)

  3/06/24 → 3/09/24

  Project: University consultancy

• EPSRC IAA Alex Simmons: Validation of Modular Toolkits for Parallel Cancer Biomarker Detection in Prostate Cancer: Approaching Enhanced Clinical Diagnostics

  Simmons, A. (PI) & Pascu, S. (CoI)

  Engineering and Physical Sciences Research Council

  1/06/24 → 7/03/25

  Project: Research council

• Evaluating the quality, safety and effectiveness of switching patients from pMDI to DPI inhalers for the treatment of asthma and COPD

  Jones, M. (PI), McGrogan, A. (CoPI), Boardman, P. (Researcher) & Zhou, N. (Researcher)

  7/05/24 → 31/08/24

  Project: Other

• Additively manufactured moisture wicking structures for breathable prosthesis liners

  Seminati, E. (CoI), Pegg, E. (CoI) & Dhokia, V. (PI)

  1/05/24 → 31/07/24

  Project: Research-related funding

  • Prosthesis 100%

• Development of Pharmacy Practice Research Capacity by enhancing engagement with clinical practice collaborators

  McGrogan, A. (PI), Mitchell, A. (CoI), Jones, S. (CoI), Jones, M. (CoI) & Rennie, T. (CoI)

  1/04/24 → 30/06/24

  Project: Research-related funding

• NextGen-O2k all-in-one Oroboros O2k Modular system for High-Resolution Respirometry

  Koumanov, F. (PI), Thompson, D. (CoI), Gonzalez, J. (CoI), Betts, J. (CoI), Walhin, J.-P. (CoI), Maher, J. (CoI), Perkin, O. (CoI), Ward, A. (CoI), Whitley, P. (CoI), Gurevich, D. (CoI), Tosh, D. (CoI) & Cevik, V. (CoI)

  1/01/24 → 31/12/24

  Project: Research-related funding

  • Respirometry 100%
  • Mitochondrial Respiration 100%
  • Mitochondrial Disorder 50%
  • Adenosine Triphosphate 50%
  • Mitochondrion 50%

• ICure: ICURE Discovery - PROTEOCARE

  Nogaret, A. (PI)

  1/10/23 → 30/11/23

  Project: Research council

  File

  • Conducting Interview 100%
  • Market Study 100%
  • ECR 100%

• Teaching development fund: Portfolio package to enable scaleable delivery and dissemination of classroom based virtual drug discovery exercises within Bath and beyond

  Flower, S. (PI) & Dodson, C. (PI)

  1/10/23 → 1/10/24

  Project: Other

• Phase 2

  Hattam, L. (Researcher), Georgiou, F. (Researcher), Pryer, T. (PI) & Nunes, M. (PI)

  1/09/23 → 1/12/23

  Project: University consultancy

• NERC GW4+: Leveraging Deep Learning to Uncover Hidden Patterns of Adverse Events in FAERS Data

  Nishtala, P. (PI) & Babbar, R. (PI)

  1/07/23 → 31/08/23

  Project: Research council

  • Deep Learning Method 100%
  • Adverse Event 100%
  • FDA Adverse Event Reporting System 100%
  • Food and Drug Administration 100%
  • Large Language Model 50%

• Spinout company formation for PHAST

  Cookson, A. (PI)

  Innovate UK, Innovate UK Business Connect

  1/03/23 → 31/12/24

  Project: Central government, health and local authorities

• HSS-GCF: Revealing insulin-sensitive glucose uptake at single molecule resolution using cryo-EM.

  Koumanov, F. (PI) & Whitley, P. (CoI)

  1/03/23 → 1/07/23

  Project: Research-related funding

  • Glucose Uptake 100%
  • Electron Microscope 100%
  • Adipose Tissue 50%
  • Maturity Onset Diabetes of the Young 50%
  • Pilot Study 50%

• A sense-act digital technology for the home-based care of diabetic foot ulcers

  Preatoni, E. (PI), Cioroianu, I. (CoI), Ehrhardt, B. (CoI), Gurevich, D. (CoI), Kreusser, L. (CoI), Lazarus, J. (CoI), Metcalfe, B. (CoI), Nishtala, P. (CoI), Sharp, T. (CoI) & Carter, J. (Researcher)

  25/02/23 → 31/07/23

  Project: Research-related funding

  • Diabetic Foot Ulcer 100%
  • Health Technology 60%
  • Digital Health 60%
  • Learning System 50%
  • Joints (Structural Components) 50%

• IAA - Delivering a commercial answer to the problem of ‘Spice’ entering UK prisons

  Pudney, C. (PI), Freeman, T. (CoI), Husbands, S. (CoI) & Cozier, G. (Researcher)

  Engineering and Physical Sciences Research Council

  1/11/22 → 31/10/24

  Project: Research council

  File

  • Cannabinoid Receptor Agonist 100%
  • Side Effect 50%
  • Indoleacetic Acid 50%
  • Cerebrovascular Accident 50%
  • Synthetic Cannabinoid 50%

• Development of a digital therapeutic intervention to improve the quality of life and reduce the healthcare costs of those living with chronic diseases

  Preatoni, E. (PI), Cioroianu, I. (PI), Ehrhardt, B. (PI), Gurevich, D. (PI), Kreusser, L. (PI), Lazarus, J. (PI), Metcalfe, B. (PI), Nishtala, P. (PI) & Sharp, T. (PI)

  1/09/22 → 28/02/23

  Project: Research-related funding

  • Diabetic Foot Ulcer 100%
  • Health Technology 100%
  • Digital Health 100%
  • Infection 11%
  • Patient Satisfaction 11%

• Multi User High-Content Confocal Microscope

  Sero, J. (PI), Cevik, V. (CoI), Gurevich, D. (CoI), Jungwirth, U. (CoI), Kelsh, R. (CoI), Koumanov, F. (CoI), Kyprianou, A. (CoI), Laabei, M. (CoI), Licchesi, J. (CoI), Murrell, A. (CoI), Pascu, S. (CoI), Turner, L. (CoI), Walko, G. (CoI), Ward, A. (CoI), Ward, S. (CoI), Williams, R. (CoI) & Zachariadis, M. (CoI)

  Biotechnology and Biological Sciences Research Council

  1/08/22 → 31/07/23

  Project: Research council

  • Confocal Microscope 100%
  • Multiuser 100%
  • Image Analysis 100%
  • Confocal Microscopy 100%
  • Fluorescence Microscope 100%

• The influence of pumping parameters on haemolysis produced by positive displacement artificial hearts: a combined experimental and numerical study

  Bornoff, J. (CoPI), Zaman, F. (CoPI), Perkins, I. L. (CoI), Cookson, A. (CoI) & Fraser, K. (CoI)

  1/07/22 → 31/07/22

  Project: Research-related funding

• GW4 Epilepsy Community

  Nogaret, A. (CoI) & Hodge, J. (PI)

  1/06/22 → 31/03/23

  Project: UK charity

  • Reflex Epilepsy 100%
  • Ion Channel 100%
  • Diseases 100%
  • Computational Method 100%

• Transdermal Diagnostics: non-invasive, affordable, continuous glucose monitoring for diabetes management and prevention

  Ilie, A. (PI) & Golbabaee, M. (CoI)

  2/05/22 → 1/05/23

  Project: Research council

• STFC CDN+ Biosensing and NIR Imaging of New Biomarkers for Prostate Cancer

  Pascu, S. (PI) & Exner, R. (Researcher)

  Science and Technology Facilities Council

  1/05/22 → 5/09/23

  Project: Research council

• An open source finite element ankle model for in-silico assessment of ankle treatment

  Pegg, E. (PI) & Gill, R. (CoI)

  Orthopaedic Research Uk

  1/04/22 → 31/12/24

  Project: UK charity

  • Joints (Structural Components) 100%
  • Finite Element Analysis 100%
  • Source Model 50%
  • Fem Model 50%
  • Rigor 33%